FR2801386A1 - Dispositif de test pour l'analyse de faibles volumes d'echantillons par des methodes immunochromatographiques - Google Patents
Dispositif de test pour l'analyse de faibles volumes d'echantillons par des methodes immunochromatographiques Download PDFInfo
- Publication number
- FR2801386A1 FR2801386A1 FR9914688A FR9914688A FR2801386A1 FR 2801386 A1 FR2801386 A1 FR 2801386A1 FR 9914688 A FR9914688 A FR 9914688A FR 9914688 A FR9914688 A FR 9914688A FR 2801386 A1 FR2801386 A1 FR 2801386A1
- Authority
- FR
- France
- Prior art keywords
- analysis
- test device
- sample
- volume
- test
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 238000012360 testing method Methods 0.000 title claims abstract description 87
- 238000004458 analytical method Methods 0.000 title claims abstract description 70
- 238000000034 method Methods 0.000 title claims abstract description 34
- 238000001727 in vivo Methods 0.000 claims abstract description 13
- 239000003153 chemical reaction reagent Substances 0.000 claims description 37
- 238000006243 chemical reaction Methods 0.000 claims description 16
- 239000000126 substance Substances 0.000 claims description 12
- PCHJSUWPFVWCPO-UHFFFAOYSA-N gold Chemical compound [Au] PCHJSUWPFVWCPO-UHFFFAOYSA-N 0.000 claims description 9
- 102000004190 Enzymes Human genes 0.000 claims description 8
- 108090000790 Enzymes Proteins 0.000 claims description 8
- 239000011324 bead Substances 0.000 claims description 6
- 239000000203 mixture Substances 0.000 claims description 6
- 238000005070 sampling Methods 0.000 claims description 6
- 238000012800 visualization Methods 0.000 claims description 6
- 239000004816 latex Chemical class 0.000 claims description 5
- 229920000126 latex Chemical class 0.000 claims description 5
- 230000001419 dependent effect Effects 0.000 claims description 3
- 239000000758 substrate Substances 0.000 claims description 3
- 238000004519 manufacturing process Methods 0.000 claims 2
- 229910052751 metal Inorganic materials 0.000 claims 1
- 239000002184 metal Substances 0.000 claims 1
- 150000002739 metals Chemical class 0.000 claims 1
- 239000013558 reference substance Substances 0.000 claims 1
- 150000003839 salts Chemical class 0.000 claims 1
- 238000001514 detection method Methods 0.000 abstract description 19
- 239000007788 liquid Substances 0.000 abstract description 4
- 238000004445 quantitative analysis Methods 0.000 abstract description 2
- 230000028327 secretion Effects 0.000 abstract description 2
- 210000004243 sweat Anatomy 0.000 abstract description 2
- 238000003149 assay kit Methods 0.000 abstract 1
- 239000012472 biological sample Substances 0.000 abstract 1
- 239000000523 sample Substances 0.000 abstract 1
- 239000012491 analyte Substances 0.000 description 34
- 238000011161 development Methods 0.000 description 22
- 239000003446 ligand Substances 0.000 description 20
- 239000012528 membrane Substances 0.000 description 19
- 230000035945 sensitivity Effects 0.000 description 13
- 239000000427 antigen Substances 0.000 description 10
- 102000036639 antigens Human genes 0.000 description 10
- 108091007433 antigens Proteins 0.000 description 10
- 238000003317 immunochromatography Methods 0.000 description 9
- 239000000463 material Substances 0.000 description 8
- 229920002678 cellulose Polymers 0.000 description 7
- 239000001913 cellulose Substances 0.000 description 7
- 238000013508 migration Methods 0.000 description 7
- 230000005012 migration Effects 0.000 description 7
- 239000000243 solution Substances 0.000 description 7
- 238000009792 diffusion process Methods 0.000 description 6
- 239000010931 gold Substances 0.000 description 6
- 229910052737 gold Inorganic materials 0.000 description 6
- 239000004677 Nylon Substances 0.000 description 5
- 239000000084 colloidal system Substances 0.000 description 5
- 230000002255 enzymatic effect Effects 0.000 description 5
- 239000012530 fluid Substances 0.000 description 5
- 229920001778 nylon Polymers 0.000 description 5
- PXFBZOLANLWPMH-UHFFFAOYSA-N 16-Epiaffinine Natural products C1C(C2=CC=CC=C2N2)=C2C(=O)CC2C(=CC)CN(C)C1C2CO PXFBZOLANLWPMH-UHFFFAOYSA-N 0.000 description 4
- 241001465754 Metazoa Species 0.000 description 4
- 239000002250 absorbent Substances 0.000 description 4
- 230000002745 absorbent Effects 0.000 description 4
- 239000000835 fiber Substances 0.000 description 4
- 238000001914 filtration Methods 0.000 description 4
- 238000003018 immunoassay Methods 0.000 description 4
- 239000003550 marker Substances 0.000 description 4
- 229920000642 polymer Polymers 0.000 description 4
- 210000001519 tissue Anatomy 0.000 description 4
- 230000000007 visual effect Effects 0.000 description 4
- 238000003745 diagnosis Methods 0.000 description 3
- 230000001900 immune effect Effects 0.000 description 3
- 238000000338 in vitro Methods 0.000 description 3
- 229910052500 inorganic mineral Inorganic materials 0.000 description 3
- 239000011707 mineral Substances 0.000 description 3
- 238000012986 modification Methods 0.000 description 3
- 230000004048 modification Effects 0.000 description 3
- 230000007170 pathology Effects 0.000 description 3
- 239000004033 plastic Substances 0.000 description 3
- 229920003023 plastic Polymers 0.000 description 3
- 229920000728 polyester Polymers 0.000 description 3
- 239000000843 powder Substances 0.000 description 3
- 230000009467 reduction Effects 0.000 description 3
- 239000007787 solid Substances 0.000 description 3
- 108060003951 Immunoglobulin Proteins 0.000 description 2
- 239000000090 biomarker Substances 0.000 description 2
- 238000004587 chromatography analysis Methods 0.000 description 2
- 238000004040 coloring Methods 0.000 description 2
- 150000001875 compounds Chemical class 0.000 description 2
- 230000008021 deposition Effects 0.000 description 2
- 238000010790 dilution Methods 0.000 description 2
- 239000012895 dilution Substances 0.000 description 2
- 102000018358 immunoglobulin Human genes 0.000 description 2
- 229940072221 immunoglobulins Drugs 0.000 description 2
- 230000003993 interaction Effects 0.000 description 2
- 244000005700 microbiome Species 0.000 description 2
- 230000003287 optical effect Effects 0.000 description 2
- 239000002245 particle Substances 0.000 description 2
- 239000000047 product Substances 0.000 description 2
- 238000007670 refining Methods 0.000 description 2
- 210000003296 saliva Anatomy 0.000 description 2
- 238000001179 sorption measurement Methods 0.000 description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 2
- 102000009027 Albumins Human genes 0.000 description 1
- 108010088751 Albumins Proteins 0.000 description 1
- 241000606161 Chlamydia Species 0.000 description 1
- 238000002965 ELISA Methods 0.000 description 1
- 239000000020 Nitrocellulose Substances 0.000 description 1
- 239000004793 Polystyrene Substances 0.000 description 1
- 206010039085 Rhinitis allergic Diseases 0.000 description 1
- 102000007562 Serum Albumin Human genes 0.000 description 1
- 108010071390 Serum Albumin Proteins 0.000 description 1
- 208000033809 Suppuration Diseases 0.000 description 1
- 206010052428 Wound Diseases 0.000 description 1
- 208000027418 Wounds and injury Diseases 0.000 description 1
- 230000002159 abnormal effect Effects 0.000 description 1
- 206010000269 abscess Diseases 0.000 description 1
- 238000010521 absorption reaction Methods 0.000 description 1
- 201000010105 allergic rhinitis Diseases 0.000 description 1
- 238000013459 approach Methods 0.000 description 1
- 238000003556 assay Methods 0.000 description 1
- 239000013060 biological fluid Substances 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 210000001124 body fluid Anatomy 0.000 description 1
- 239000010839 body fluid Substances 0.000 description 1
- 238000012512 characterization method Methods 0.000 description 1
- 239000007795 chemical reaction product Substances 0.000 description 1
- 230000002860 competitive effect Effects 0.000 description 1
- 230000000295 complement effect Effects 0.000 description 1
- 238000011109 contamination Methods 0.000 description 1
- 230000007423 decrease Effects 0.000 description 1
- 238000002405 diagnostic procedure Methods 0.000 description 1
- 239000000975 dye Substances 0.000 description 1
- 238000010828 elution Methods 0.000 description 1
- 230000002550 fecal effect Effects 0.000 description 1
- 235000013305 food Nutrition 0.000 description 1
- 239000011521 glass Substances 0.000 description 1
- 239000003365 glass fiber Substances 0.000 description 1
- 230000036541 health Effects 0.000 description 1
- 230000002209 hydrophobic effect Effects 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 238000011534 incubation Methods 0.000 description 1
- 238000009776 industrial production Methods 0.000 description 1
- 208000015181 infectious disease Diseases 0.000 description 1
- 230000002458 infectious effect Effects 0.000 description 1
- 239000002085 irritant Substances 0.000 description 1
- 231100000021 irritant Toxicity 0.000 description 1
- BWHLPLXXIDYSNW-UHFFFAOYSA-N ketorolac tromethamine Chemical compound OCC(N)(CO)CO.OC(=O)C1CCN2C1=CC=C2C(=O)C1=CC=CC=C1 BWHLPLXXIDYSNW-UHFFFAOYSA-N 0.000 description 1
- 238000002372 labelling Methods 0.000 description 1
- 235000013372 meat Nutrition 0.000 description 1
- 230000004060 metabolic process Effects 0.000 description 1
- 239000002207 metabolite Substances 0.000 description 1
- MYWUZJCMWCOHBA-VIFPVBQESA-N methamphetamine Chemical compound CN[C@@H](C)CC1=CC=CC=C1 MYWUZJCMWCOHBA-VIFPVBQESA-N 0.000 description 1
- 238000002156 mixing Methods 0.000 description 1
- 238000012544 monitoring process Methods 0.000 description 1
- 230000036651 mood Effects 0.000 description 1
- 210000004877 mucosa Anatomy 0.000 description 1
- 210000003097 mucus Anatomy 0.000 description 1
- 229920001220 nitrocellulos Polymers 0.000 description 1
- 239000012466 permeate Substances 0.000 description 1
- 229920002223 polystyrene Polymers 0.000 description 1
- 239000002243 precursor Substances 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 238000012545 processing Methods 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 238000011002 quantification Methods 0.000 description 1
- 230000002285 radioactive effect Effects 0.000 description 1
- 239000000941 radioactive substance Substances 0.000 description 1
- 230000036632 reaction speed Effects 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 210000002966 serum Anatomy 0.000 description 1
- 230000004936 stimulating effect Effects 0.000 description 1
- 235000019722 synbiotics Nutrition 0.000 description 1
- 210000001138 tear Anatomy 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- 230000001988 toxicity Effects 0.000 description 1
- 231100000419 toxicity Toxicity 0.000 description 1
- 238000005406 washing Methods 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Physics & Mathematics (AREA)
- Heart & Thoracic Surgery (AREA)
- Molecular Biology (AREA)
- Pathology (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Optics & Photonics (AREA)
- Medical Informatics (AREA)
- Biophysics (AREA)
- Surgery (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Priority Applications (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9914688A FR2801386A1 (fr) | 1999-11-19 | 1999-11-19 | Dispositif de test pour l'analyse de faibles volumes d'echantillons par des methodes immunochromatographiques |
| PCT/FR2000/003219 WO2001036964A2 (fr) | 1999-11-19 | 2000-11-20 | Dispositif de test pour des echantillons de petits volumes (1 a 100 microlitres) |
| EP00981444A EP1305629A2 (fr) | 1999-11-19 | 2000-11-20 | Dispositif de test pour des echantillons de petits volumes (1 a 100 microlitres) |
| KR1020027006706A KR20030031878A (ko) | 1999-11-19 | 2000-11-20 | 적은 부피 (1 내지 100 ㎕)의 시료를 위한 시험 장치 |
| JP2001538801A JP4470354B2 (ja) | 1999-11-19 | 2000-11-20 | １〜１００ｕｌの試料のためのインビボ検査装置 |
| AU18691/01A AU1869101A (en) | 1999-11-19 | 2000-11-20 | Device for testing in vivo samples between 1 to 100 mul |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9914688A FR2801386A1 (fr) | 1999-11-19 | 1999-11-19 | Dispositif de test pour l'analyse de faibles volumes d'echantillons par des methodes immunochromatographiques |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| FR2801386A1 true FR2801386A1 (fr) | 2001-05-25 |
Family
ID=9552408
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR9914688A Withdrawn FR2801386A1 (fr) | 1999-11-19 | 1999-11-19 | Dispositif de test pour l'analyse de faibles volumes d'echantillons par des methodes immunochromatographiques |
Country Status (6)
| Country | Link |
|---|---|
| EP (1) | EP1305629A2 (enExample) |
| JP (1) | JP4470354B2 (enExample) |
| KR (1) | KR20030031878A (enExample) |
| AU (1) | AU1869101A (enExample) |
| FR (1) | FR2801386A1 (enExample) |
| WO (1) | WO2001036964A2 (enExample) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7066623B2 (en) * | 2003-12-19 | 2006-06-27 | Soo Ghee Lee | Method and apparatus for producing untainted white light using off-white light emitting diodes |
| DE602005016527D1 (de) * | 2004-02-09 | 2009-10-22 | Rapid Pathogen Screening Inc | Verfahren zur schnelldiagnose von zielen in menschlichen körperflüssigkeiten |
| US8445293B2 (en) | 2005-02-09 | 2013-05-21 | Rapid Pathogen Screening, Inc. | Method to increase specificity and/or accuracy of lateral flow immunoassays |
| ES2582784T3 (es) * | 2009-04-09 | 2016-09-15 | Hitachi Chemical Company, Ltd. | Detector y método de detección |
Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0362809A1 (en) * | 1988-10-06 | 1990-04-11 | BOEHRINGER BIOCHEMIA ROBIN S.p.A. | Device and method for the detection of an analyte |
| WO1994006012A1 (en) * | 1992-09-03 | 1994-03-17 | Boehringer Mannheim Corporation | Analytical test apparatus with on board negative and positive control |
| WO1995027205A1 (en) * | 1994-03-30 | 1995-10-12 | Epitope, Inc. | Saliva assay method and device |
| WO1995035502A1 (en) * | 1994-06-17 | 1995-12-28 | Trinity Biotech Inc. | Device for detecting polyvalent substances |
| US5648274A (en) * | 1991-05-29 | 1997-07-15 | Smithkline Diagnostics, Inc. | Competitive immunoassay device |
| EP0806666A2 (en) * | 1996-05-09 | 1997-11-12 | Syntron Bioresearch, Inc. | Method and apparatus for single step assays of whole blood |
-
1999
- 1999-11-19 FR FR9914688A patent/FR2801386A1/fr not_active Withdrawn
-
2000
- 2000-11-20 EP EP00981444A patent/EP1305629A2/fr not_active Withdrawn
- 2000-11-20 WO PCT/FR2000/003219 patent/WO2001036964A2/fr not_active Ceased
- 2000-11-20 JP JP2001538801A patent/JP4470354B2/ja not_active Expired - Lifetime
- 2000-11-20 KR KR1020027006706A patent/KR20030031878A/ko not_active Ceased
- 2000-11-20 AU AU18691/01A patent/AU1869101A/en not_active Abandoned
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0362809A1 (en) * | 1988-10-06 | 1990-04-11 | BOEHRINGER BIOCHEMIA ROBIN S.p.A. | Device and method for the detection of an analyte |
| US5648274A (en) * | 1991-05-29 | 1997-07-15 | Smithkline Diagnostics, Inc. | Competitive immunoassay device |
| WO1994006012A1 (en) * | 1992-09-03 | 1994-03-17 | Boehringer Mannheim Corporation | Analytical test apparatus with on board negative and positive control |
| WO1995027205A1 (en) * | 1994-03-30 | 1995-10-12 | Epitope, Inc. | Saliva assay method and device |
| WO1995035502A1 (en) * | 1994-06-17 | 1995-12-28 | Trinity Biotech Inc. | Device for detecting polyvalent substances |
| EP0806666A2 (en) * | 1996-05-09 | 1997-11-12 | Syntron Bioresearch, Inc. | Method and apparatus for single step assays of whole blood |
Also Published As
| Publication number | Publication date |
|---|---|
| WO2001036964A3 (fr) | 2001-11-22 |
| AU1869101A (en) | 2001-05-30 |
| JP2005529305A (ja) | 2005-09-29 |
| EP1305629A2 (fr) | 2003-05-02 |
| WO2001036964B1 (fr) | 2002-07-25 |
| JP4470354B2 (ja) | 2010-06-02 |
| KR20030031878A (ko) | 2003-04-23 |
| WO2001036964A2 (fr) | 2001-05-25 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| Kroll et al. | Interference with clinical laboratory analyses | |
| EP0410998B1 (fr) | Dispositif et procede pour la determination qualitative et quantitative rapide de la presence d'un ligand reactif dans un fluide | |
| US4624929A (en) | Sample collector and assay device and method for its use | |
| US4849340A (en) | Reaction system element and method for performing prothrombin time assay | |
| JP4672263B2 (ja) | 簡便な検出法、検出装置及び検出キットとその製法 | |
| US20030045001A1 (en) | Immunochromatographic test strip with arcuate sample application zone for ease-of-use in the field | |
| JPH11503025A (ja) | 現在のグルコースレベルおよび中期間または長期間の血糖症制御のための組み合わせアッセイ | |
| EP0334947B1 (fr) | Dispositif de detection immunoenzymatique | |
| FR2514511A1 (fr) | Dispositif et procede pour determiner la presence d'antigenes | |
| CN110412265A (zh) | 使用反应时间的校准分析 | |
| JP3757171B2 (ja) | 微生物抗原の抽出方法 | |
| KR20190058357A (ko) | 고농도 검체 내 표적물질 정량화가 가능한 광범위 체외 진단 키트 | |
| JPWO2009136476A1 (ja) | バイオセンサの製造方法およびバイオセンサ | |
| Gomes et al. | Low-cost, disposable biosensor for detection of the brain-derived neurotrophic factor biomarker in noninvasively collected saliva toward diagnosis of mental disorders | |
| FR2976505A1 (fr) | Dispositif et procede pour immunoessais | |
| JP2001502052A (ja) | 液体移動および干渉に対する抵抗を改良した診断用検査デバイス | |
| JP2015087293A (ja) | グリコアルブミンの測定キットおよび測定方法 | |
| EP1305629A2 (fr) | Dispositif de test pour des echantillons de petits volumes (1 a 100 microlitres) | |
| US20100176279A1 (en) | Methods and materials for detecting light released from a labeling material | |
| WO2000043786A1 (fr) | Dispositif de test et procede immunochromatographiques | |
| JPS63210772A (ja) | 乾燥試験片及びそれを用いた被検流体中の分析成分の検出方法 | |
| WO1996010179A1 (fr) | Diagnostic direct d'haptenes | |
| NZ526754A (en) | Test device | |
| US20080014657A1 (en) | Use of Albumin, Bovine, P-Aminophenyl N-Acetyl B-D Glucosaminide as a Control Line for an Immunoassay Device | |
| JP2007139658A (ja) | アレルゲン検出方法及びアレルゲン検出装置 |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ST | Notification of lapse |
Effective date: 20070731 |