FR2655340B1 - Procede de preparation de produits intermediaires pour la preparation de diltiazem. - Google Patents

Procede de preparation de produits intermediaires pour la preparation de diltiazem.

Info

Publication number
FR2655340B1
FR2655340B1 FR909014781A FR9014781A FR2655340B1 FR 2655340 B1 FR2655340 B1 FR 2655340B1 FR 909014781 A FR909014781 A FR 909014781A FR 9014781 A FR9014781 A FR 9014781A FR 2655340 B1 FR2655340 B1 FR 2655340B1
Authority
FR
France
Prior art keywords
preparation
diltiazem
intermediate products
products
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
FR909014781A
Other languages
English (en)
Other versions
FR2655340A1 (fr
Inventor
Claudio Giordano
Roberto Casagrande
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Zambon Group SpA
Zambon SpA
Original Assignee
Zambon Group SpA
Zambon SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zambon Group SpA, Zambon SpA filed Critical Zambon Group SpA
Publication of FR2655340A1 publication Critical patent/FR2655340A1/fr
Application granted granted Critical
Publication of FR2655340B1 publication Critical patent/FR2655340B1/fr
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D281/00—Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one sulfur atom as the only ring hetero atoms
    • C07D281/02—Seven-membered rings
    • C07D281/04—Seven-membered rings having the hetero atoms in positions 1 and 4
    • C07D281/08—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D281/10—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems condensed with one six-membered ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FR909014781A 1989-12-06 1990-11-27 Procede de preparation de produits intermediaires pour la preparation de diltiazem. Expired - Lifetime FR2655340B1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT02263789A IT1237526B (it) 1989-12-06 1989-12-06 Processo di preparazione di un intermedio per il diltiazem

Publications (2)

Publication Number Publication Date
FR2655340A1 FR2655340A1 (fr) 1991-06-07
FR2655340B1 true FR2655340B1 (fr) 1994-10-14

Family

ID=11198703

Family Applications (1)

Application Number Title Priority Date Filing Date
FR909014781A Expired - Lifetime FR2655340B1 (fr) 1989-12-06 1990-11-27 Procede de preparation de produits intermediaires pour la preparation de diltiazem.

Country Status (13)

Country Link
US (1) US5102999A (fr)
JP (1) JP2987714B2 (fr)
AT (1) AT401650B (fr)
BE (1) BE1003317A3 (fr)
CA (1) CA2030866C (fr)
CH (1) CH680443A5 (fr)
DE (1) DE4038676C2 (fr)
ES (1) ES2023774A6 (fr)
FR (1) FR2655340B1 (fr)
GB (1) GB2239014B (fr)
IT (1) IT1237526B (fr)
NL (1) NL194204C (fr)
SE (1) SE509634C2 (fr)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH09501178A (ja) * 1993-08-06 1997-02-04 スミスクライン・ビーチャム・コーポレイション エンドセリン受容体アンタゴニスト
EP0723449A1 (fr) * 1993-08-06 1996-07-31 Smithkline Beecham Corporation Antagonistes du recepteur de l'endotheline
IL121525A0 (en) * 1996-08-26 1998-02-08 Tanabe Seiyaku Co Process for preparing optically active benzothiazepine compound and intermediate therefor
IT1295376B1 (it) * 1997-10-22 1999-05-12 Zambon Spa Processo per il riciclo di un sottoprodotto della sintesi del diltiazem
CN100364540C (zh) * 2006-03-14 2008-01-30 北京大学 (2s-顺)-(+)-2,3-二氢-3-羟基-2-(4-甲氧苯基)-1,5-苯并硫氮杂䓬-4(5h)-酮在制备治疗肝炎的药物中的用途
CN100463904C (zh) * 2006-08-15 2009-02-25 宁波工程学院 地尔硫卓中间体的制备方法
CN103755663B (zh) * 2014-01-26 2016-02-24 武汉工程大学 地尔硫卓中间体副产物L-cis-内酰胺的回收工艺
CN110284181A (zh) * 2019-08-07 2019-09-27 山东新华制药股份有限公司 地尔硫卓ab异构体的单晶制备方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3562257A (en) * 1967-10-28 1971-02-09 Tanabe Seiyaku Co Benzothiazepine derivatives
EP0059335B1 (fr) * 1981-02-27 1985-05-15 Tanabe Seiyaku Co., Ltd. Procédé pour la préparation des esters de l'acide thréo-hydroxy-2 (méthoxy-4 phényl)-3 (nitro-2 phénylthio)-3 propionique
SE449611B (sv) * 1982-07-09 1987-05-11 Tanabe Seiyaku Co Sett att framstella 1,5-bensotiazepinderivat
JPS5920273A (ja) * 1982-07-27 1984-02-01 Tanabe Seiyaku Co Ltd ベンゾチアゼピン誘導体の新規製造法
IT1152721B (it) * 1982-10-15 1987-01-07 Luso Farmaco Inst Risoluzione ottica dell'acido dl-alfa-2-idrossi-3-(4-metossifenil)-3-(2-amminofeniltio)propionico
JPS6025982A (ja) * 1983-07-22 1985-02-08 Tanabe Seiyaku Co Ltd ベンゾチアゼピン誘導体の製法
JPS6032779A (ja) * 1983-08-01 1985-02-19 Hamari Yakuhin Kogyo Kk ベンゾチアゼピン誘導体の新規製造法

Also Published As

Publication number Publication date
GB2239014A (en) 1991-06-19
BE1003317A3 (fr) 1992-02-25
ATA240890A (de) 1996-03-15
CA2030866C (fr) 2001-03-13
IT8922637A1 (it) 1991-06-06
ES2023774A6 (es) 1992-02-01
FR2655340A1 (fr) 1991-06-07
US5102999A (en) 1992-04-07
GB9025887D0 (en) 1991-01-09
CH680443A5 (fr) 1992-08-31
NL9002529A (nl) 1991-07-01
AT401650B (de) 1996-10-25
DE4038676C2 (de) 1999-06-02
SE9003860D0 (sv) 1990-12-05
GB2239014B (en) 1993-09-22
SE509634C2 (sv) 1999-02-15
NL194204B (nl) 2001-05-01
NL194204C (nl) 2001-09-04
DE4038676A1 (de) 1991-06-13
JP2987714B2 (ja) 1999-12-06
JPH03193770A (ja) 1991-08-23
IT8922637A0 (it) 1989-12-06
SE9003860L (sv) 1991-06-07
IT1237526B (it) 1993-06-08
CA2030866A1 (fr) 1991-06-07

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Legal Events

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TP Transmission of property