FR2636947B1 - Composes de pyrrolidinone et de piperidinone et compositions pharmaceutiques les contenant - Google Patents

Composes de pyrrolidinone et de piperidinone et compositions pharmaceutiques les contenant

Info

Publication number
FR2636947B1
FR2636947B1 FR8911400A FR8911400A FR2636947B1 FR 2636947 B1 FR2636947 B1 FR 2636947B1 FR 8911400 A FR8911400 A FR 8911400A FR 8911400 A FR8911400 A FR 8911400A FR 2636947 B1 FR2636947 B1 FR 2636947B1
Authority
FR
France
Prior art keywords
pyrrolidinone
pharmaceutical compositions
compositions containing
piperidinone compounds
piperidinone
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR8911400A
Other languages
English (en)
Other versions
FR2636947A1 (fr
Inventor
Sung J Lee
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Biofor Ltd
Original Assignee
Biofor Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biofor Ltd filed Critical Biofor Ltd
Publication of FR2636947A1 publication Critical patent/FR2636947A1/fr
Application granted granted Critical
Publication of FR2636947B1 publication Critical patent/FR2636947B1/fr
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24—Oxygen or sulfur atoms
    • C07D207/26—2-Pyrrolidones
    • C07D207/263—2-Pyrrolidones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms
    • C07D207/27—2-Pyrrolidones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms with substituted hydrocarbon radicals directly attached to the ring nitrogen atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D211/72—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D211/74—Oxygen atoms
    • C07D211/76—Oxygen atoms attached in position 2 or 6
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/0803—Compounds with Si-C or Si-Si linkages
    • C07F7/081—Compounds with Si-C or Si-Si linkages comprising at least one atom selected from the elements N, O, halogen, S, Se or Te
    • C07F7/0812—Compounds with Si-C or Si-Si linkages comprising at least one atom selected from the elements N, O, halogen, S, Se or Te comprising a heterocyclic ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Immunology (AREA)
  • Rheumatology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
FR8911400A 1988-09-26 1989-08-30 Composes de pyrrolidinone et de piperidinone et compositions pharmaceutiques les contenant Expired - Fee Related FR2636947B1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/248,942 US4959482A (en) 1988-09-26 1988-09-26 Pyrrolidinone compounds and pharamaceutical compositions containing same

Publications (2)

Publication Number Publication Date
FR2636947A1 FR2636947A1 (fr) 1990-03-30
FR2636947B1 true FR2636947B1 (fr) 1994-10-28

Family

ID=22941364

Family Applications (1)

Application Number Title Priority Date Filing Date
FR8911400A Expired - Fee Related FR2636947B1 (fr) 1988-09-26 1989-08-30 Composes de pyrrolidinone et de piperidinone et compositions pharmaceutiques les contenant

Country Status (8)

Country Link
US (1) US4959482A (fr)
JP (1) JPH02129167A (fr)
AU (1) AU3893289A (fr)
BE (1) BE1003692A4 (fr)
DE (1) DE3932068A1 (fr)
FR (1) FR2636947B1 (fr)
GB (1) GB2223014B (fr)
SE (1) SE500670C2 (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5128330A (en) * 1991-02-19 1992-07-07 Biofor, Ltd. Oxazinone substituted phosphines
US5256091A (en) * 1991-11-06 1993-10-26 Outboard Marine Corporation Shift interlock system
WO1993010117A1 (fr) * 1991-11-15 1993-05-27 American Cyanamid Company Procede de preparation d'un agent de reticulation triazine tris-lactame, et compositions durcissables contenant cet agent
ES2393632T3 (es) * 2006-08-09 2012-12-26 Glaxosmithkline Llc Pirrolidinona anilinas como moduladores de los receptores de progesterona

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE754141A (fr) * 1969-08-04 1971-02-01 Pfizer Esters d'alpha-carboxyarylmethyl penicillines
US3717659A (en) * 1970-06-09 1973-02-20 Merck & Co Inc Heterocyclic salicylic acid derivatives
US3718743A (en) * 1970-11-19 1973-02-27 Merck & Co Inc 5-phenyl-2-piperidones and 5-phenyl-2-thiopiperidones in compositions and methods for treating pain, fever and inflammation
US3790597A (en) * 1971-04-12 1974-02-05 Ciba Geigy Corp Sulfur derivatives of alkylhydroxyphenyl maleimides and compositions thereof
US3906002A (en) * 1973-12-28 1975-09-16 John F Stephen Hindered phenolic norbornane-2,3-dicarboximides
US4124725A (en) * 1977-05-16 1978-11-07 Riker Laboratories, Inc. Anti-inflammatory method
US4172082A (en) * 1977-05-16 1979-10-23 Riker Laboratories, Inc. Substituted thiophenes
US4636516A (en) * 1981-02-19 1987-01-13 Yamanouchi Pharmaceutical Co., Ltd. 3,5-di-tert-butyl-4-hydroxyphenyl-substituted heterocyclic compounds
US4357345A (en) * 1981-11-23 1982-11-02 Riker Laboratories, Inc. Substituted furans
EP0106988A1 (fr) * 1982-09-02 1984-05-02 The Wellcome Foundation Limited Dérivés de lactame ayant des propriétés pharmaceutiques
US4743606A (en) * 1986-03-25 1988-05-10 Boehringer Ingelheim Pharmaceuticals, Inc. 3-[2-(3',5'-di-t-butyl-4'-hydroxyphenyl)ethenyl]pyridine having anti-inflammatory and anti-arthritic properties

Also Published As

Publication number Publication date
AU3893289A (en) 1990-03-29
SE8902608L (sv) 1990-03-27
US4959482A (en) 1990-09-25
GB2223014A (en) 1990-03-28
GB2223014B (en) 1992-03-18
SE500670C2 (sv) 1994-08-08
GB8920270D0 (en) 1989-10-18
FR2636947A1 (fr) 1990-03-30
DE3932068A1 (de) 1990-03-29
JPH02129167A (ja) 1990-05-17
BE1003692A4 (fr) 1992-05-26
SE8902608D0 (sv) 1989-07-27

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Legal Events

Date Code Title Description
TP Transmission of property
ST Notification of lapse