SE8902608D0 - Pyrrolidinone and piperidinone compounds and pharmaceutical compositions containing same - Google Patents
Pyrrolidinone and piperidinone compounds and pharmaceutical compositions containing sameInfo
- Publication number
- SE8902608D0 SE8902608D0 SE8902608A SE8902608A SE8902608D0 SE 8902608 D0 SE8902608 D0 SE 8902608D0 SE 8902608 A SE8902608 A SE 8902608A SE 8902608 A SE8902608 A SE 8902608A SE 8902608 D0 SE8902608 D0 SE 8902608D0
- Authority
- SE
- Sweden
- Prior art keywords
- compounds
- pyrrolidinone
- pharmaceutical compositions
- compositions containing
- containing same
- Prior art date
Links
- XUWHAWMETYGRKB-UHFFFAOYSA-N piperidin-2-one Chemical class O=C1CCCCN1 XUWHAWMETYGRKB-UHFFFAOYSA-N 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- HNJBEVLQSNELDL-UHFFFAOYSA-N pyrrolidin-2-one Chemical compound O=C1CCCN1 HNJBEVLQSNELDL-UHFFFAOYSA-N 0.000 title 1
- 230000000202 analgesic effect Effects 0.000 abstract 1
- 230000003110 anti-inflammatory effect Effects 0.000 abstract 1
- 230000001754 anti-pyretic effect Effects 0.000 abstract 1
- 206010003246 arthritis Diseases 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 238000009472 formulation Methods 0.000 abstract 1
- 230000002519 immonomodulatory effect Effects 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 229910052757 nitrogen Inorganic materials 0.000 abstract 1
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 1
- 239000000546 pharmaceutical excipient Substances 0.000 abstract 1
- HNJBEVLQSNELDL-YZRHJBSPSA-N pyrrolidin-2-one Chemical class O=C1CC[14CH2]N1 HNJBEVLQSNELDL-YZRHJBSPSA-N 0.000 abstract 1
- 125000000026 trimethylsilyl group Chemical group [H]C([H])([H])[Si]([*])(C([H])([H])[H])C([H])([H])[H] 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/24—Oxygen or sulfur atoms
- C07D207/26—2-Pyrrolidones
- C07D207/263—2-Pyrrolidones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms
- C07D207/27—2-Pyrrolidones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms with substituted hydrocarbon radicals directly attached to the ring nitrogen atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D211/72—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D211/74—Oxygen atoms
- C07D211/76—Oxygen atoms attached in position 2 or 6
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/0803—Compounds with Si-C or Si-Si linkages
- C07F7/081—Compounds with Si-C or Si-Si linkages comprising at least one atom selected from the elements N, O, halogen, S, Se or Te
- C07F7/0812—Compounds with Si-C or Si-Si linkages comprising at least one atom selected from the elements N, O, halogen, S, Se or Te comprising a heterocyclic ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pain & Pain Management (AREA)
- Immunology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyrrole Compounds (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US07/248,942 US4959482A (en) | 1988-09-26 | 1988-09-26 | Pyrrolidinone compounds and pharamaceutical compositions containing same |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| SE8902608D0 true SE8902608D0 (sv) | 1989-07-27 |
| SE8902608L SE8902608L (sv) | 1990-03-27 |
| SE500670C2 SE500670C2 (sv) | 1994-08-08 |
Family
ID=22941364
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SE8902608A SE500670C2 (sv) | 1988-09-26 | 1989-07-27 | Pyrrolidin- och piperidonföreningar och farmaceutiska kompositioner innehållande dessa |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US4959482A (sv) |
| JP (1) | JPH02129167A (sv) |
| AU (1) | AU3893289A (sv) |
| BE (1) | BE1003692A4 (sv) |
| DE (1) | DE3932068A1 (sv) |
| FR (1) | FR2636947B1 (sv) |
| GB (1) | GB2223014B (sv) |
| SE (1) | SE500670C2 (sv) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5128330A (en) * | 1991-02-19 | 1992-07-07 | Biofor, Ltd. | Oxazinone substituted phosphines |
| US5256091A (en) * | 1991-11-06 | 1993-10-26 | Outboard Marine Corporation | Shift interlock system |
| EP0570563A1 (en) * | 1991-11-15 | 1993-11-24 | Cytec Technology Corp. | A process for preparing a triazine tris-lactam crosslinking agent and curable compositions containing the same |
| KR20090035695A (ko) * | 2006-08-09 | 2009-04-10 | 스미스클라인 비참 코포레이션 | 프로게스테론 수용체 조정인자로서의 피롤리디논 아닐린 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE754141A (fr) * | 1969-08-04 | 1971-02-01 | Pfizer | Esters d'alpha-carboxyarylmethyl penicillines |
| US3717659A (en) * | 1970-06-09 | 1973-02-20 | Merck & Co Inc | Heterocyclic salicylic acid derivatives |
| US3718743A (en) * | 1970-11-19 | 1973-02-27 | Merck & Co Inc | 5-phenyl-2-piperidones and 5-phenyl-2-thiopiperidones in compositions and methods for treating pain, fever and inflammation |
| US3790597A (en) * | 1971-04-12 | 1974-02-05 | Ciba Geigy Corp | Sulfur derivatives of alkylhydroxyphenyl maleimides and compositions thereof |
| US3906002A (en) * | 1973-12-28 | 1975-09-16 | John F Stephen | Hindered phenolic norbornane-2,3-dicarboximides |
| US4124725A (en) * | 1977-05-16 | 1978-11-07 | Riker Laboratories, Inc. | Anti-inflammatory method |
| US4172082A (en) * | 1977-05-16 | 1979-10-23 | Riker Laboratories, Inc. | Substituted thiophenes |
| US4636516A (en) * | 1981-02-19 | 1987-01-13 | Yamanouchi Pharmaceutical Co., Ltd. | 3,5-di-tert-butyl-4-hydroxyphenyl-substituted heterocyclic compounds |
| US4357345A (en) * | 1981-11-23 | 1982-11-02 | Riker Laboratories, Inc. | Substituted furans |
| DK399083A (da) * | 1982-09-02 | 1984-03-03 | Wellcome Found | Fremgangsmaade til fremstilling af benzo- eller pyridin-derivater |
| US4743606A (en) * | 1986-03-25 | 1988-05-10 | Boehringer Ingelheim Pharmaceuticals, Inc. | 3-[2-(3',5'-di-t-butyl-4'-hydroxyphenyl)ethenyl]pyridine having anti-inflammatory and anti-arthritic properties |
-
1988
- 1988-09-26 US US07/248,942 patent/US4959482A/en not_active Expired - Fee Related
-
1989
- 1989-07-25 AU AU38932/89A patent/AU3893289A/en not_active Abandoned
- 1989-07-27 SE SE8902608A patent/SE500670C2/sv unknown
- 1989-08-30 FR FR8911400A patent/FR2636947B1/fr not_active Expired - Fee Related
- 1989-09-05 BE BE8900947A patent/BE1003692A4/fr not_active IP Right Cessation
- 1989-09-07 GB GB8920270A patent/GB2223014B/en not_active Expired - Fee Related
- 1989-09-26 JP JP1248226A patent/JPH02129167A/ja active Pending
- 1989-09-26 DE DE3932068A patent/DE3932068A1/de not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| DE3932068A1 (de) | 1990-03-29 |
| SE500670C2 (sv) | 1994-08-08 |
| US4959482A (en) | 1990-09-25 |
| GB8920270D0 (en) | 1989-10-18 |
| JPH02129167A (ja) | 1990-05-17 |
| AU3893289A (en) | 1990-03-29 |
| GB2223014A (en) | 1990-03-28 |
| GB2223014B (en) | 1992-03-18 |
| BE1003692A4 (fr) | 1992-05-26 |
| FR2636947A1 (fr) | 1990-03-30 |
| SE8902608L (sv) | 1990-03-27 |
| FR2636947B1 (fr) | 1994-10-28 |
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