FR2621821A1 - Produits biologiques, procede pour leur preparation et pour leur utilisation en therapeutique - Google Patents

Produits biologiques, procede pour leur preparation et pour leur utilisation en therapeutique Download PDF

Info

Publication number
FR2621821A1
FR2621821A1 FR8811256A FR8811256A FR2621821A1 FR 2621821 A1 FR2621821 A1 FR 2621821A1 FR 8811256 A FR8811256 A FR 8811256A FR 8811256 A FR8811256 A FR 8811256A FR 2621821 A1 FR2621821 A1 FR 2621821A1
Authority
FR
France
Prior art keywords
inhibitor
assay
activity
cells
protein
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
FR8811256A
Other languages
English (en)
French (fr)
Inventor
Jean-Michel Dayer
Philippe Seckinger
Gonzalo Jose Mazzei
Alan Reed Shaw
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Biogen Inc
Original Assignee
Biogen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22218720&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=FR2621821(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Biogen Inc filed Critical Biogen Inc
Publication of FR2621821A1 publication Critical patent/FR2621821A1/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4702Regulators; Modulating activity
    • C07K14/4703Inhibitors; Suppressors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Veterinary Medicine (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pyridine Compounds (AREA)
FR8811256A 1987-08-26 1988-08-26 Produits biologiques, procede pour leur preparation et pour leur utilisation en therapeutique Withdrawn FR2621821A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US8963287A 1987-08-26 1987-08-26

Publications (1)

Publication Number Publication Date
FR2621821A1 true FR2621821A1 (fr) 1989-04-21

Family

ID=22218720

Family Applications (1)

Application Number Title Priority Date Filing Date
FR8811256A Withdrawn FR2621821A1 (fr) 1987-08-26 1988-08-26 Produits biologiques, procede pour leur preparation et pour leur utilisation en therapeutique

Country Status (20)

Country Link
EP (1) EP0341273B1 (ja)
JP (2) JP3014099B2 (ja)
KR (2) KR0138919B1 (ja)
AT (1) ATE147408T1 (ja)
AU (1) AU633471B2 (ja)
BE (1) BE1002375A3 (ja)
CA (1) CA1341026C (ja)
DE (1) DE3855747T2 (ja)
DK (1) DK175837B1 (ja)
ES (3) ES2015348A6 (ja)
FR (1) FR2621821A1 (ja)
GB (1) GB2220662A (ja)
HK (1) HK1007748A1 (ja)
IL (1) IL87543A0 (ja)
IT (1) IT1226855B (ja)
NL (1) NL8820676A (ja)
NZ (1) NZ225940A (ja)
SE (1) SE8901342D0 (ja)
WO (1) WO1989001946A1 (ja)
ZA (1) ZA886251B (ja)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5075222A (en) * 1988-05-27 1991-12-24 Synergen, Inc. Interleukin-1 inhibitors
US6159460A (en) * 1988-05-27 2000-12-12 Amgen Inc. Method for treating interleukin-1 mediated diseases
KR0148009B1 (ko) * 1988-05-27 1998-08-01 그래고리 비. 아보트 인터루킨-1 억제제
JP3192651B2 (ja) * 1988-05-27 2001-07-30 アムジェン,インコーポレーテッド インターロイキン―1インヒビター
US6858409B1 (en) 1988-05-27 2005-02-22 Amgen Inc. Nucleic acids encoding interleukin-1 inhibitors and processes for preparing interleukin-1 inhibitors
AU651955B2 (en) * 1989-11-29 1994-08-11 Amgen, Inc. Production of recombinant human interleukin-1 inhibitor
US5714140A (en) * 1989-12-13 1998-02-03 Otsuka Pharmaceutical Co., Ltd. Method for inhibiting the production of bioactive IL-1 by administering M-CSF
US6552170B1 (en) 1990-04-06 2003-04-22 Amgen Inc. PEGylation reagents and compounds formed therewith
WO1991017184A1 (en) * 1990-04-27 1991-11-14 The Upjohn Company Modified interleukin-1 inhibitors
WO1991017249A1 (en) * 1990-05-01 1991-11-14 Cetus Corporation Interleukin-1 antagonist and uses thereof
WO1997009984A1 (en) * 1995-09-13 1997-03-20 Takeda Chemical Industries, Ltd. Immunosuppressant
US6294170B1 (en) 1997-08-08 2001-09-25 Amgen Inc. Composition and method for treating inflammatory diseases

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4992367A (en) * 1986-05-12 1991-02-12 Hoffmann-La Roche Inc. Enhanced expression of human interleukin-2 in mammalian cells

Also Published As

Publication number Publication date
IT8821743A0 (it) 1988-08-25
DE3855747D1 (de) 1997-02-20
NL8820676A (nl) 1989-07-03
IL87543A0 (en) 1989-01-31
NZ225940A (en) 1992-06-25
EP0341273B1 (en) 1997-01-08
JP3217752B2 (ja) 2001-10-15
KR0138919B1 (ko) 1998-04-30
DK203189A (da) 1989-04-26
JPH10327862A (ja) 1998-12-15
SE8901342L (sv) 1989-04-13
ATE147408T1 (de) 1997-01-15
JP3014099B2 (ja) 2000-02-28
AU2427288A (en) 1989-03-31
ZA886251B (en) 1990-04-25
KR890701629A (ko) 1989-12-21
JPH02500643A (ja) 1990-03-08
HK1007748A1 (en) 1999-04-23
ES2017275A6 (es) 1991-01-16
KR0138654B1 (ko) 1998-04-30
EP0341273A4 (en) 1990-09-19
DK203189D0 (da) 1989-04-26
DK175837B1 (da) 2005-03-21
IT1226855B (it) 1991-02-19
DE3855747T2 (de) 1997-06-12
WO1989001946A1 (en) 1989-03-09
BE1002375A3 (fr) 1991-01-22
GB2220662A (en) 1990-01-17
GB8912533D0 (en) 1989-08-02
EP0341273A1 (en) 1989-11-15
ES2015348A6 (es) 1990-08-16
AU633471B2 (en) 1993-02-04
CA1341026C (en) 2000-06-13
ES2017274A6 (es) 1991-01-16
SE8901342D0 (sv) 1989-04-13

Similar Documents

Publication Publication Date Title
Dinarello Overview of the IL‐1 family in innate inflammation and acquired immunity
US5359032A (en) Interkeukin-1 inhibitor
Huang et al. Molecular and biological characterization of the murine leukotriene B4 receptor expressed on eosinophils
Standiford et al. IL-4 inhibits the expression of IL-8 from stimulated human monocytes.
Cariuk et al. Induction of cachexia in mice by a product isolated from the urine of cachectic cancer patients
Desreumaux et al. Synthesis of interleukin-5 by activated eosinophils in patients with eosinophilic heart diseases
Dinarello Modalities for reducing interleukin 1 activity in disease
JP2002517977A (ja) Tnfリガンドファミリーのntn−2メンバー
KR19980064719A (ko) 인터로이킨-18-수용체 단백질
FR2621821A1 (fr) Produits biologiques, procede pour leur preparation et pour leur utilisation en therapeutique
JP2006182783A (ja) リンパ球化学誘引因子およびその用途
KR19980079551A (ko) 폴리펩티드
Pereira Cytokine production in patients on dialysis
EP0504257A1 (en) [Ala IL-8] 77 AS A LEUKOCYTE ADHESION INHIBITOR
KR100237936B1 (ko) 인터루킨-1 길항제
JPH10500850A (ja) インターロイキン−6 スプライス変異体
US20090305985A1 (en) Immunomodulatory Agents For Treatment of Inflammatory Diseases
Schmidt et al. Species-dependent stereospecific serum protein binding of the oral anticoagulant drug phenprocoumon
JPH10506538A (ja) Gp130に全く結合することができないヒトインターロイキン−6の拮抗薬、および医薬化合物の製造におけるそれらの使用
JP4360902B2 (ja) 融合タンパク質
Colotta et al. Interleukin 1
AU2002319524A1 (en) A fusion protein
A. Dinarello IL‐1 Superfamily and Inflammasome
EP0368711A1 (fr) Procédé d'isolement d'interleukine-2 glycosylée et interleukine-2 glycosylée
DK175969B1 (da) Fremgangsmåde til oprensning af interleukin 1 inhibitorer

Legal Events

Date Code Title Description
ST Notification of lapse