FR2567123B1 - Nouveaux composes polycycliques heterocycliques derives du benzimidazole, du benzoxazole ou du benzothiazole, procede et intermediaire pour leur preparation ainsi que leur utilisation pharmaceutique, en particulier pour le traitement d'affections gastriques - Google Patents
Nouveaux composes polycycliques heterocycliques derives du benzimidazole, du benzoxazole ou du benzothiazole, procede et intermediaire pour leur preparation ainsi que leur utilisation pharmaceutique, en particulier pour le traitement d'affections gastriquesInfo
- Publication number
- FR2567123B1 FR2567123B1 FR858510337A FR8510337A FR2567123B1 FR 2567123 B1 FR2567123 B1 FR 2567123B1 FR 858510337 A FR858510337 A FR 858510337A FR 8510337 A FR8510337 A FR 8510337A FR 2567123 B1 FR2567123 B1 FR 2567123B1
- Authority
- FR
- France
- Prior art keywords
- benzoxazole
- benzothiazole
- benzimidazole
- preparation
- treatment
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/74—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C65/00—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C65/21—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing ether groups, groups, groups, or groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/89—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members with hetero atoms directly attached to the ring nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/04—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to the ring carbon atoms
- C07D215/06—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to the ring carbon atoms having only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached to the ring nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/12—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/12—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D215/14—Radicals substituted by oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
- C07D235/28—Sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
- C07D263/08—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D263/10—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
- C07D263/08—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D263/10—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D263/14—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with radicals substituted by oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
- C07D277/62—Benzothiazoles
- C07D277/68—Benzothiazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
- C07D277/70—Sulfur atoms
- C07D277/74—Sulfur atoms substituted by carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (9)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB848417271A GB8417271D0 (en) | 1984-07-06 | 1984-07-06 | Biologically active nitrogen heterocycles |
GB848417272A GB8417272D0 (en) | 1984-07-06 | 1984-07-06 | Biologically active nitrogen heterocycles |
GB848419738A GB8419738D0 (en) | 1984-08-02 | 1984-08-02 | Nitrogen heterocycles |
GB848424346A GB8424346D0 (en) | 1984-09-26 | 1984-09-26 | Nitrogen heterocycles |
GB848424351A GB8424351D0 (en) | 1984-09-26 | 1984-09-26 | Nitrogen heterocycles |
GB848424347A GB8424347D0 (en) | 1984-09-26 | 1984-09-26 | Nitrogen heterocycles |
GB848424350A GB8424350D0 (en) | 1984-09-26 | 1984-09-26 | Nitrogen heterocycles |
GB848430163A GB8430163D0 (en) | 1984-11-29 | 1984-11-29 | Biologically active nitrogen heterocycles |
GB858509406A GB8509406D0 (en) | 1985-04-12 | 1985-04-12 | Nitrogen heterocycles |
Publications (2)
Publication Number | Publication Date |
---|---|
FR2567123A1 FR2567123A1 (fr) | 1986-01-10 |
FR2567123B1 true FR2567123B1 (fr) | 1991-05-31 |
Family
ID=27576300
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR858510337A Expired - Lifetime FR2567123B1 (fr) | 1984-07-06 | 1985-07-05 | Nouveaux composes polycycliques heterocycliques derives du benzimidazole, du benzoxazole ou du benzothiazole, procede et intermediaire pour leur preparation ainsi que leur utilisation pharmaceutique, en particulier pour le traitement d'affections gastriques |
Country Status (15)
Country | Link |
---|---|
EP (1) | EP0174717B1 (fr) |
AU (1) | AU580607B2 (fr) |
CA (1) | CA1341314C (fr) |
CH (1) | CH666265A5 (fr) |
DE (1) | DE3585252D1 (fr) |
DK (1) | DK174021B1 (fr) |
FI (1) | FI89046C (fr) |
FR (1) | FR2567123B1 (fr) |
GR (1) | GR851618B (fr) |
HK (1) | HK60194A (fr) |
IL (1) | IL75687A (fr) |
LU (1) | LU85989A1 (fr) |
NO (1) | NO168355C (fr) |
NZ (1) | NZ212664A (fr) |
PT (1) | PT80783B (fr) |
Families Citing this family (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU4640985A (en) * | 1984-08-31 | 1986-03-06 | Nippon Chemiphar Co. Ltd. | Benzimidazole derivatives |
JO1406B1 (en) * | 1984-11-02 | 1986-11-30 | سميث كلاين اند فرينش لابوراتوريز ليمتد | Chemical compounds |
DK8600939A (fr) * | 1985-03-05 | 1986-09-06 | ||
EP0232399A1 (fr) * | 1985-08-21 | 1987-08-19 | Byk Gulden Lomberg Chemische Fabrik GmbH | Nouvelles amines, leur procede de fabrication, leur utilisation, et medicaments les contenant |
AR243167A1 (es) | 1985-08-24 | 1993-07-30 | Hoechst Ag | Procedimiento para la preparacion de toluidinas sustituidas. |
JPS62246587A (ja) * | 1986-03-17 | 1987-10-27 | ピ−ピ−ジ− インダストリイズ,インコ−ポレイテツド | 除草活性を有する置換ベンゾオキサゾロン(またはベンゾチアゾロン)化合物 |
ES2038612T3 (es) * | 1986-03-28 | 1993-08-01 | Otsuka Pharmaceutical Co., Ltd. | Compuestos de hidroquinolina, composiciones que los contienen y procedimientos para prepararlas. |
AU619444B2 (en) * | 1986-06-02 | 1992-01-30 | Nippon Chemiphar Co. Ltd. | 2-(2-aminobenzylsulfinyl)- benzimidazole derivatives |
EP0251536A1 (fr) * | 1986-06-24 | 1988-01-07 | FISONS plc | Benzimidazoles, leur préparation, formulation et utilisation comme inhibiteurs de sécrétion d'acide gastrique |
WO1988002367A1 (fr) * | 1986-09-27 | 1988-04-07 | Fisons Plc | Composes |
SE8604566D0 (sv) * | 1986-10-27 | 1986-10-27 | Haessle Ab | Novel compunds |
FI91754C (fi) * | 1986-12-02 | 1994-08-10 | Tanabe Seiyaku Co | Analogiamenetelmä lääkeaineena käyttökelpoisen imidatsolijohdannaisen valmistamiseksi |
AU597628B2 (en) * | 1987-03-30 | 1990-06-07 | Higuchi, Yoshinari | Hydroquinoline compounds, compositions containing same and process for preparing same |
US4942245A (en) * | 1987-04-20 | 1990-07-17 | Kyorin Pharmaceutical Co., Ltd. | Benzimidazole Derivatives |
IT1216522B (it) * | 1988-03-25 | 1990-03-08 | Dompe Farmaceutici Spa | Derivati alchiltiobenzimidazolici attivi farmacologicamente eprocedimento per la loro preparazione. |
US5294629A (en) * | 1988-11-22 | 1994-03-15 | Meiji Seika Kaisha, Ltd. | Benzothiazole and benzimidazole derivatives and antiulcer agent containing the same |
EP0370436A3 (fr) * | 1988-11-22 | 1990-10-31 | Meiji Seika Kaisha Ltd. | Benzothiazoles et benzimidazole et compositions anti-ulcère les contenant |
JP2933739B2 (ja) * | 1990-04-09 | 1999-08-16 | 明治製菓株式会社 | チアゾールまたはイミダゾール誘導体および抗潰瘍剤 |
EP2022789A1 (fr) * | 2007-08-06 | 2009-02-11 | Farmaprojects, S.A. | Procédé pour la préparation d'un inhibiteur de la sécrétion d'acide gastrique |
CL2017001982A1 (es) * | 2017-08-03 | 2018-04-20 | Neuroinnovation Ltda | Nuevos compuestos derivados de piridinmetilsulfinilbenzoxazoles y piridinmetilsulfinibenzotiazoles, marcados radiactivamente o con fluorescencia y sus composiciones, como biomarcadores especificos para el diagnostico de enfermedades neurodegenerativas y patologías involucradas con la proteína tau. |
Family Cites Families (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR1003821A (fr) | 1947-02-28 | 1952-03-26 | Francolor Sa | Procédé d'obtention d'un produit organique contenant du soufre et de l'oxygène, et son application comme accélérateur de vulcanisation |
US2585155A (en) | 1949-10-29 | 1952-02-12 | Francolor Sa | Benzothiazole-2-dimethylsulfinamide and process for preparing the same |
US3541060A (en) | 1967-06-01 | 1970-11-17 | Monsanto Chemicals | Accelerating vulcanization with benzothiazole-2-sulfinamides |
BE738304A (fr) | 1968-10-02 | 1970-03-02 | ||
FR2037001A1 (fr) | 1969-04-30 | 1970-12-31 | Ugine Kuhlmann | Nouveaux dérivés du mercaptobenzothiazole |
BE788805A (fr) * | 1971-09-22 | 1973-01-02 | Lafon Victor | Nouveaux derives antalgiques de la serie des arylamines soufrees |
SE416649B (sv) | 1974-05-16 | 1981-01-26 | Haessle Ab | Forfarande for framstellning av foreningar som paverkar magsyrasekretionen |
IN148930B (fr) * | 1977-09-19 | 1981-07-25 | Hoffmann La Roche | |
SE7804231L (sv) | 1978-04-14 | 1979-10-15 | Haessle Ab | Magsyrasekretionsmedel |
US4359465A (en) * | 1980-07-28 | 1982-11-16 | The Upjohn Company | Methods for treating gastrointestinal inflammation |
US4472409A (en) * | 1981-11-05 | 1984-09-18 | Byk Gulden Lomberg Chemische Fabrik Gesellschaft Mit Beschrankter Haftung | 2-Pyridylmethyl thio(sulfinyl)benzimidazoles with gastric acid secretion inhibiting effects |
SE8300736D0 (sv) | 1983-02-11 | 1983-02-11 | Haessle Ab | Novel pharmacologically active compounds |
GR81595B (fr) | 1983-06-18 | 1984-12-11 | Wyeth John & Brother Ltd | |
CA1259070A (fr) | 1983-07-01 | 1989-09-05 | Upjohn Company (The) | Derives de substitution de 2-¬noyaux condenses (3,4- 4,5-, 5,6-)-pyridylalcoylenesulfinyl|- benzimidazoles |
GB8417171D0 (en) | 1984-07-05 | 1984-08-08 | Beecham Group Plc | Compounds |
SE8404065D0 (sv) | 1984-08-10 | 1984-08-10 | Haessle Ab | Novel biologically active compounds |
JPS6150978A (ja) | 1984-08-16 | 1986-03-13 | Takeda Chem Ind Ltd | ピリジン誘導体およびその製造法 |
AU4640985A (en) | 1984-08-31 | 1986-03-06 | Nippon Chemiphar Co. Ltd. | Benzimidazole derivatives |
EP0178438A1 (fr) | 1984-09-19 | 1986-04-23 | Beecham Group Plc | Composés |
JO1406B1 (en) * | 1984-11-02 | 1986-11-30 | سميث كلاين اند فرينش لابوراتوريز ليمتد | Chemical compounds |
US4738709A (en) * | 1985-01-10 | 1988-04-19 | Ppg Industries, Inc. | Herbicidally active substituted benzisoxazoles |
DK8600939A (fr) * | 1985-03-05 | 1986-09-06 |
-
1985
- 1985-06-28 DE DE8585304626T patent/DE3585252D1/de not_active Expired - Lifetime
- 1985-06-28 CA CA000485915A patent/CA1341314C/fr not_active Expired - Fee Related
- 1985-06-28 EP EP85304626A patent/EP0174717B1/fr not_active Expired - Lifetime
- 1985-07-01 IL IL75687A patent/IL75687A/xx not_active IP Right Cessation
- 1985-07-01 AU AU44441/85A patent/AU580607B2/en not_active Expired
- 1985-07-02 GR GR851618A patent/GR851618B/el unknown
- 1985-07-02 DK DK198503018A patent/DK174021B1/da not_active IP Right Cessation
- 1985-07-03 FI FI852622A patent/FI89046C/fi not_active IP Right Cessation
- 1985-07-04 CH CH2873/85A patent/CH666265A5/fr not_active IP Right Cessation
- 1985-07-05 NO NO852729A patent/NO168355C/no not_active IP Right Cessation
- 1985-07-05 LU LU85989A patent/LU85989A1/fr unknown
- 1985-07-05 PT PT80783A patent/PT80783B/pt unknown
- 1985-07-05 FR FR858510337A patent/FR2567123B1/fr not_active Expired - Lifetime
- 1985-07-05 NZ NZ212664A patent/NZ212664A/xx unknown
-
1994
- 1994-06-23 HK HK60194A patent/HK60194A/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
FI89046C (fi) | 1993-08-10 |
FR2567123A1 (fr) | 1986-01-10 |
DK301885A (da) | 1986-01-07 |
FI852622L (fi) | 1986-01-07 |
EP0174717A1 (fr) | 1986-03-19 |
IL75687A (en) | 1990-03-19 |
EP0174717B1 (fr) | 1992-01-22 |
FI852622A0 (fi) | 1985-07-03 |
GR851618B (fr) | 1985-11-26 |
CA1341314C (fr) | 2001-11-06 |
DK174021B1 (da) | 2002-04-22 |
NZ212664A (en) | 1989-04-26 |
AU4444185A (en) | 1986-01-09 |
PT80783A (en) | 1985-08-01 |
AU580607B2 (en) | 1989-01-19 |
NO168355B (no) | 1991-11-04 |
CH666265A5 (fr) | 1988-07-15 |
DK301885D0 (da) | 1985-07-02 |
NO852729L (no) | 1986-01-07 |
LU85989A1 (fr) | 1986-02-12 |
NO168355C (no) | 1992-02-12 |
HK60194A (en) | 1994-07-08 |
PT80783B (pt) | 1989-10-04 |
DE3585252D1 (de) | 1992-03-05 |
FI89046B (fi) | 1993-04-30 |
IL75687A0 (en) | 1985-11-29 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
FR2567123B1 (fr) | Nouveaux composes polycycliques heterocycliques derives du benzimidazole, du benzoxazole ou du benzothiazole, procede et intermediaire pour leur preparation ainsi que leur utilisation pharmaceutique, en particulier pour le traitement d'affections gastriques | |
ES510042A0 (es) | "un procedimiento de preparacion de nuevas carboxamidas heterociclicas". | |
FR2540490B1 (fr) | Procede de resolution d'isomeres optiques, les isomeres ainsi produits et leur application pharmaceutique | |
LU81297A1 (fr) | Procede enzymatique microbiologique pour la production d'aminoacides optiquement actifs en partant d'hydantoines et/ou de derives carbamoyle racemiques | |
FR2397403A1 (fr) | Nouveaux derives de 1-acyl 2-cyano-aziridine, procede pour leur preparation et compositions pharmaceutiques contenant ces composes | |
MY106038A (en) | 4-quinoline carboxylic acid derivatives useful as immunosuppressive agents. | |
FR2504127B1 (fr) | Nouveaux derives d'acides phenyl aliphatique carboxyliques, procede pour leur preparation et leur application comme medicaments | |
BE893492A (fr) | Procede de preparation d'esters d'acides apovincaminiques, esters ainsi obtenus et compositions pharmaceutiques prepares avec ces esters | |
FR2565105B1 (fr) | Composition pharmaceutique stable pour le traitement de la cetose et procede pour la preparer | |
PT85278A (fr) | Procede de preparation d:une fraction immunogene active a liegard des bilharzioses et de compositions immunisantes la contenant | |
BE894228A (fr) | Composition pharmaceutique pour le traitement de l'atherosclerose | |
FR2603285B1 (fr) | Procede de silylation d'imides aromatiques et silylimides ainsi prepares | |
FR2640140B1 (fr) | Compositions pour le traitement de phlebectasies et leur procede de preparation | |
FR2620931B1 (fr) | Dispositif et procede pour le traitement d'affections des gencives | |
FR2566408B1 (fr) | Nouveaux pro-medicaments heterocycliques d'oxicams anti-inflammatoires et leur procede de preparation | |
FR2562798B1 (fr) | Agent pharmaceutique pour le traitement du psoriasis | |
FR2585020B1 (fr) | Nouvelle substance biologiquement active, appelee girolline, extraite de l'eponge pseudaxinyssa cantharella, son procede de preparation et les compositions pharmaceutiques qui la contiennent | |
OA08609A (fr) | Composition pharmaceutique pour le traitement des infections bactériennes. | |
FR2533917B1 (fr) | Derives 15-cycloaliphatiques de 13,14-bisdeshydro-carboprostacyclines et procede pour leur preparation | |
BE894154A (fr) | Procede de preparation d'esters des acides alkoxyvincaminiques et alkoxyapovincaminiques | |
FR2615852B1 (fr) | Procede pour la preparation et l'isolement de nitriles aromatiques | |
FR2619489B1 (fr) | Electroplasmolyseur pour le traitement de matieres vegetales | |
FR2518995B1 (fr) | Procede de preparation de derives heterocycliques d'acide acetique et derives ainsi obtenus | |
FR2518998B1 (fr) | Nouveaux derives heterocycliques d'acide acetique et procede pour leur preparation | |
BE883791A (fr) | Amides d'acides pyrrolidine-(2)-one(1)-yle-alcoylcarboxyliques, leur preparation et leur utilisation pour le traitement de troubles de l'irrigation cerebrale |