FR2547594B1 - Nouveaux complexes antitumoraux antibiotiques et leur procede de production par culture d'une souche d'actinomadura verrucosospora - Google Patents

Nouveaux complexes antitumoraux antibiotiques et leur procede de production par culture d'une souche d'actinomadura verrucosospora

Info

Publication number
FR2547594B1
FR2547594B1 FR8407477A FR8407477A FR2547594B1 FR 2547594 B1 FR2547594 B1 FR 2547594B1 FR 8407477 A FR8407477 A FR 8407477A FR 8407477 A FR8407477 A FR 8407477A FR 2547594 B1 FR2547594 B1 FR 2547594B1
Authority
FR
France
Prior art keywords
culture
strain
production
novel antibiotic
actinomadura verrucosospora
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
FR8407477A
Other languages
English (en)
French (fr)
Other versions
FR2547594A1 (fr
Inventor
Masataka Konishi
Kyoichiro Saitoh
Hiroaki Ohkuma
Hiroshi Kawaguchi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bristol Myers Co
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of FR2547594A1 publication Critical patent/FR2547594A1/fr
Application granted granted Critical
Publication of FR2547594B1 publication Critical patent/FR2547594B1/fr
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P1/00—Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes
    • C12P1/02—Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes by using fungi
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
    • C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
    • C07H13/08—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals directly attached to carbocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H11/00—Compounds containing saccharide radicals esterified by inorganic acids; Metal salts thereof
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P1/00—Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes
    • C12P1/06—Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes by using actinomycetales

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Mycology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FR8407477A 1983-05-16 1984-05-15 Nouveaux complexes antitumoraux antibiotiques et leur procede de production par culture d'une souche d'actinomadura verrucosospora Expired FR2547594B1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US49523183A 1983-05-16 1983-05-16

Publications (2)

Publication Number Publication Date
FR2547594A1 FR2547594A1 (fr) 1984-12-21
FR2547594B1 true FR2547594B1 (fr) 1988-03-25

Family

ID=23967812

Family Applications (1)

Application Number Title Priority Date Filing Date
FR8407477A Expired FR2547594B1 (fr) 1983-05-16 1984-05-15 Nouveaux complexes antitumoraux antibiotiques et leur procede de production par culture d'une souche d'actinomadura verrucosospora

Country Status (28)

Country Link
JP (2) JPS59232094A (pt)
KR (2) KR840008817A (pt)
AT (1) AT393691B (pt)
AU (1) AU569294B2 (pt)
BE (1) BE899667A (pt)
CA (1) CA1241282A (pt)
CY (1) CY1465A (pt)
DE (1) DE3418023A1 (pt)
DK (1) DK163127C (pt)
ES (1) ES8700267A1 (pt)
FI (1) FI81114C (pt)
FR (1) FR2547594B1 (pt)
GB (1) GB2141425B (pt)
GR (1) GR81581B (pt)
HK (1) HK9889A (pt)
HU (1) HU193928B (pt)
IE (1) IE57444B1 (pt)
IL (1) IL71824A (pt)
IT (1) IT1175498B (pt)
KE (1) KE3846A (pt)
LU (1) LU85362A1 (pt)
NL (1) NL8401572A (pt)
NZ (1) NZ208013A (pt)
PT (1) PT78590A (pt)
SE (1) SE460364B (pt)
SU (1) SU1344249A3 (pt)
YU (1) YU43846B (pt)
ZA (1) ZA843591B (pt)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GR78648B (pt) * 1982-07-26 1984-09-27 Bristol Myers Co
IL79519A0 (en) * 1985-08-27 1986-10-31 Bristol Myers Co Bbm-1675c and d antitumor antibiotics
US4837206A (en) * 1987-04-29 1989-06-06 Bristol-Myers Company Esperamicin derivatives
US4996305A (en) * 1988-02-29 1991-02-26 American Cyanamid Company Process for producing the antibiotic and antitumor agents LL-E33288.epsilon.ε-Br
CA2027601A1 (en) * 1989-11-06 1991-05-07 Koko Sugawara Antitumor antibiotic bu-3983t
CN115380211A (zh) * 2021-03-17 2022-11-22 日本水产株式会社 精制的方法和经精制的产品

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4195079A (en) * 1979-01-31 1980-03-25 Pfizer Inc. New polycyclic ether antibiotic
JPS56113791A (en) * 1980-02-15 1981-09-07 Kaken Pharmaceut Co Ltd Novel antibiotic and its preparation
GR78648B (pt) * 1982-07-26 1984-09-27 Bristol Myers Co
US4539203A (en) * 1984-11-13 1985-09-03 Warner-Lambert Company CL-1577D And CL-1577E antibiotic/antitumor compounds, their production and use

Also Published As

Publication number Publication date
LU85362A1 (fr) 1985-03-21
IT8420928A1 (it) 1985-11-15
DK163127C (da) 1992-06-09
IE57444B1 (en) 1992-09-09
ZA843591B (en) 1985-02-27
GR81581B (pt) 1984-12-11
ATA160984A (de) 1991-05-15
YU43846B (en) 1989-12-31
IT8420928A0 (it) 1984-05-15
HK9889A (en) 1989-02-10
ES532476A0 (es) 1986-09-16
FI841906A0 (fi) 1984-05-11
DE3418023C2 (pt) 1988-08-18
NZ208013A (en) 1987-07-31
GB2141425A (en) 1984-12-19
SE8402619L (sv) 1984-11-17
DK163127B (da) 1992-01-20
BE899667A (fr) 1984-11-16
PT78590A (en) 1984-06-01
AU2779184A (en) 1984-11-22
KR900019562A (ko) 1990-12-24
FI81114B (fi) 1990-05-31
ES8700267A1 (es) 1986-09-16
KR840008817A (ko) 1984-12-19
SU1344249A3 (ru) 1987-10-07
GB2141425B (en) 1986-12-03
IL71824A0 (en) 1984-09-30
NL8401572A (nl) 1984-12-17
KE3846A (en) 1989-04-07
SE8402619D0 (sv) 1984-05-15
AU569294B2 (en) 1988-01-28
SE460364B (sv) 1989-10-02
JPH0229079B2 (pt) 1990-06-27
DK239784A (da) 1984-11-17
IE841200L (en) 1984-11-16
DE3418023A1 (de) 1984-11-22
FR2547594A1 (fr) 1984-12-21
HU193928B (en) 1987-12-28
FI81114C (fi) 1990-09-10
AT393691B (de) 1991-11-25
CY1465A (en) 1989-07-21
YU84984A (en) 1988-04-30
GB8412368D0 (en) 1984-06-20
JPH0555111B2 (pt) 1993-08-16
JPS59232094A (ja) 1984-12-26
CA1241282A (en) 1988-08-30
IT1175498B (it) 1987-07-01
FI841906A (fi) 1984-11-17
HUT37168A (en) 1985-11-28
DK239784D0 (da) 1984-05-15
JPH02128693A (ja) 1990-05-17
KR920001366B1 (ko) 1992-02-11
IL71824A (en) 1988-09-30

Similar Documents

Publication Publication Date Title
FR2501207B1 (fr) Composes quinazoliniques antitumoraux et leur procede de production
FR2582294B1 (fr) Procede de production d'alumine-beta
EP0166368A3 (en) Process for production of high to ultra-high molecular weight linear polyarylenesulfides
FR2593513B1 (fr) Procede de production d'essence
FR2558156B1 (fr) Procede de produ
BE878902A (fr) Procede de production d'alkylene-glycols
FR2616793B1 (fr) Procede de production de noir de carbone
FR2564101B1 (fr) Procede perfectionne d'esterification de la colophane par le pentaerythritol
FR2555603B1 (fr) Procede de production d'enzymes cellulolytiques
FR2527650B1 (fr) Procede de production par voie solide d'articles multiples a structure monocristalline
FR2573431B1 (fr) Procede de production d'un polymere
BE879401A (fr) Nouveaux antibiotiques peptidiques et leur procede de production
BE893913A (fr) Procede de production de polymeres d'alphaolefines
FR2547594B1 (fr) Nouveaux complexes antitumoraux antibiotiques et leur procede de production par culture d'une souche d'actinomadura verrucosospora
PT81493A (en) Process for producing antitumor antibiotics (ll-e 33288 complex)
FR2527448B1 (fr) Procede de production d'interferon
FR2504131B1 (fr) Procede de production de dithioacides organiques et leur application
FR2637913B1 (fr) Procede de production de polysaccharides par fermentation d'une source hydrocarbonee a l'aide de microorganismes
BE888562A (fr) Procede de production d'une preparation enzymatique de fructosyl-transferase,
BE881609A (fr) Procede de production et d'isolement de methyltertiobutylether
FR2573771B1 (fr) Procede de production de peroxydase
FR2517697B1 (fr) Nouveaux aminoglycosides antibiotiques appeles saccharocines et leur production
MA20567A1 (fr) Nouveaux derives de la thierropyridine ainsi qu'un procede pour leur preparation
FR2460328B1 (fr) Procede de production de creatinase et culture du microorganisme producteur
FR2623511B1 (fr) Procede de production de polymeres d'organophosphazene