FR2533210B1 - - Google Patents

Info

Publication number
FR2533210B1
FR2533210B1 FR8215832A FR8215832A FR2533210B1 FR 2533210 B1 FR2533210 B1 FR 2533210B1 FR 8215832 A FR8215832 A FR 8215832A FR 8215832 A FR8215832 A FR 8215832A FR 2533210 B1 FR2533210 B1 FR 2533210B1
Authority
FR
France
Prior art keywords
group
lone
carbon atoms
electron pair
pair donor
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
FR8215832A
Other languages
English (en)
French (fr)
Other versions
FR2533210A1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Universite Claude Bernard Lyon 1
Original Assignee
Universite Claude Bernard Lyon 1
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Universite Claude Bernard Lyon 1 filed Critical Universite Claude Bernard Lyon 1
Priority to FR8215832A priority Critical patent/FR2533210A1/fr
Priority to JP58170541A priority patent/JPS5973559A/ja
Priority to GR72445A priority patent/GR81273B/el
Priority to DE8383420149T priority patent/DE3362324D1/de
Priority to AU19165/83A priority patent/AU562104B2/en
Priority to IL69733A priority patent/IL69733A0/xx
Priority to EP83420149A priority patent/EP0107597B1/fr
Priority to AT83420149T priority patent/ATE18236T1/de
Priority to US06/532,499 priority patent/US4645678A/en
Priority to PT77351A priority patent/PT77351B/pt
Priority to NO833338A priority patent/NO158418C/no
Priority to DK424783A priority patent/DK424783A/da
Priority to CA000436906A priority patent/CA1244007A/fr
Priority to ES525680A priority patent/ES525680A0/es
Priority to ZA836892A priority patent/ZA836892B/xx
Priority to NZ205616A priority patent/NZ205616A/en
Publication of FR2533210A1 publication Critical patent/FR2533210A1/fr
Application granted granted Critical
Publication of FR2533210B1 publication Critical patent/FR2533210B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06104—Dipeptides with the first amino acid being acidic
    • C07K5/06113—Asp- or Asn-amino acid
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L27/00—Spices; Flavouring agents or condiments; Artificial sweetening agents; Table salts; Dietetic salt substitutes; Preparation or treatment thereof
    • A23L27/30—Artificial sweetening agents
    • A23L27/31—Artificial sweetening agents containing amino acids, nucleotides, peptides or derivatives
    • A23L27/32—Artificial sweetening agents containing amino acids, nucleotides, peptides or derivatives containing dipeptides or derivatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06104—Dipeptides with the first amino acid being acidic
    • C07K5/06113—Asp- or Asn-amino acid
    • C07K5/06121—Asp- or Asn-amino acid the second amino acid being aromatic or cycloaliphatic
    • C07K5/0613—Aspartame

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Nutrition Science (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Seasonings (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)
  • Oscillators With Electromechanical Resonators (AREA)
  • Ultra Sonic Daignosis Equipment (AREA)
  • Tea And Coffee (AREA)
  • Indole Compounds (AREA)
  • General Preparation And Processing Of Foods (AREA)
  • Jellies, Jams, And Syrups (AREA)
  • Pyrrole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
FR8215832A 1982-09-17 1982-09-17 Edulcorants de synthese Granted FR2533210A1 (fr)

Priority Applications (16)

Application Number Priority Date Filing Date Title
FR8215832A FR2533210A1 (fr) 1982-09-17 1982-09-17 Edulcorants de synthese
JP58170541A JPS5973559A (ja) 1982-09-17 1983-09-14 合成甘味物質
DE8383420149T DE3362324D1 (en) 1982-09-17 1983-09-15 Chemical compounds and their use as sweetening agents
AU19165/83A AU562104B2 (en) 1982-09-17 1983-09-15 Substituted ureas and thioureas as sweeteners
IL69733A IL69733A0 (en) 1982-09-17 1983-09-15 Phenylurea derivatives and their use as sweetening agents
EP83420149A EP0107597B1 (fr) 1982-09-17 1983-09-15 Composés chimiques et utilisation comme édulcorants
AT83420149T ATE18236T1 (de) 1982-09-17 1983-09-15 Chemische verbindungen und verwendung als suessstoff.
US06/532,499 US4645678A (en) 1982-09-17 1983-09-15 Sweetening agents
GR72445A GR81273B (enExample) 1982-09-17 1983-09-15
NO833338A NO158418C (no) 1982-09-17 1983-09-16 Soetningsmidler.
PT77351A PT77351B (fr) 1982-09-17 1983-09-16 Procede pour la preparation de derives d'aminoacides ayant un effet edulcorant
DK424783A DK424783A (da) 1982-09-17 1983-09-16 Soedemidler
CA000436906A CA1244007A (fr) 1982-09-17 1983-09-16 Procede pour la preparation d'edulcorants de preparation synthese, les edulcorants ainsi obtenus ainsi que leurs applications a la preparation de substances consommables sucrees
ES525680A ES525680A0 (es) 1982-09-17 1983-09-16 Procedimiento para la preparacion de derivados de amino acidos, de efecto edulcorante
ZA836892A ZA836892B (en) 1982-09-17 1983-09-16 Synthetic sweeteners
NZ205616A NZ205616A (en) 1982-09-17 1983-09-16 Synthetic sweetening compounds and compositions

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8215832A FR2533210A1 (fr) 1982-09-17 1982-09-17 Edulcorants de synthese

Publications (2)

Publication Number Publication Date
FR2533210A1 FR2533210A1 (fr) 1984-03-23
FR2533210B1 true FR2533210B1 (enExample) 1984-11-23

Family

ID=9277590

Family Applications (1)

Application Number Title Priority Date Filing Date
FR8215832A Granted FR2533210A1 (fr) 1982-09-17 1982-09-17 Edulcorants de synthese

Country Status (16)

Country Link
US (1) US4645678A (enExample)
EP (1) EP0107597B1 (enExample)
JP (1) JPS5973559A (enExample)
AT (1) ATE18236T1 (enExample)
AU (1) AU562104B2 (enExample)
CA (1) CA1244007A (enExample)
DE (1) DE3362324D1 (enExample)
DK (1) DK424783A (enExample)
ES (1) ES525680A0 (enExample)
FR (1) FR2533210A1 (enExample)
GR (1) GR81273B (enExample)
IL (1) IL69733A0 (enExample)
NO (1) NO158418C (enExample)
NZ (1) NZ205616A (enExample)
PT (1) PT77351B (enExample)
ZA (1) ZA836892B (enExample)

Families Citing this family (59)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2575163B1 (fr) * 1984-12-20 1987-03-20 Sanofi Sa Tri- et tetrapeptides reduits inhibiteurs de la secretion gastrique, procede d'obtention et compositions pharmaceutiques les contenant
US4833128A (en) * 1984-12-28 1989-05-23 Neil Solomon Dietary supplement
US4921939A (en) * 1985-03-19 1990-05-01 Universite Claude Bernard -Lyon 1 Sweetening agents
FR2606404B2 (fr) * 1986-04-10 1991-11-22 Univ Claude Bernard Lyon Nouveaux composes chimiques derivant de l'acide phenylguanidinoacetique et leur utilisation comme agents edulcorants
FR2579201B1 (fr) * 1985-03-19 1987-05-07 Bernard Lyon I Universite Clau Composes chimiques perfectionnes, utilisation comme agents edulcorants et compositions contenant de tels agents
FR2579202B1 (fr) * 1985-03-19 1988-04-29 Univ Claude Bernard Lyon Nouveaux composes chimiques, utilisation comme agents edulcorants et compositions contenant de tels agents
FR2608379B1 (fr) * 1986-12-23 1989-03-24 Univ Claude Bernard Lyon Agents edulcorants derives des acides n-phenylguanidinoacetique et n-phenylethanamidinoacetique, procede pour edulcorer des produits divers, et compositions contenant de tels agents edulcorants
JPS61260052A (ja) * 1985-05-14 1986-11-18 Ajinomoto Co Inc 新規アミノ酸誘導体および甘味剤
KR870008526A (ko) * 1986-03-13 1987-10-19 원본미기재 감미료 및 그 제조방법
US4818899A (en) * 1986-12-03 1989-04-04 Minnesota Mining And Manufacturing Company Second harmonic generation by carbamic acid derivatives
FR2609603B1 (fr) * 1987-01-15 1989-03-24 Univ Claude Bernard Lyon Agents edulcorants derives des acides guanidinoacetique et ethanamidinoacetique, procede pour edulcorer des produits divers, et compositions contenant de tels agents edulcorants
JPH0655730B2 (ja) * 1987-07-17 1994-07-27 ザ ヌトラスウィート カンパニー 強力甘味剤
US4900740A (en) * 1987-10-02 1990-02-13 The Nutrasweet Company N,N'-disubstituted guanidines containing a carboxyl or a tetrazolyl moiety
FR2624698A1 (fr) * 1987-12-18 1989-06-23 Bernard Lyon I Universite Clau Derives heterocycliques de n-carbamoyl-, n-thiocarbamoyl- ou n-amidino-aminomalonyl ou aminosuccinyl amides utiles comme agents edulcorants
FR2624699B1 (fr) * 1987-12-18 1990-04-13 Bernard Lyon I Universite Clau Derives heterocycliques de n-carbamoyl-, n-thiocarbamoyl- ou n-amidino-glycine ou beta-alanine utiles comme agents edulcorants
FR2630304B1 (fr) * 1988-04-22 1990-08-31 Bernard Lyon I Universite Clau Derives n-hydrocarbones des acides aspartique et glutamique alpha-monoamides utiles comme agents edulcorants
JP2791156B2 (ja) * 1988-08-23 1998-08-27 ザ ヌトラスウィート カンパニー 強力甘味料としての置換アリール尿素
US5266717A (en) * 1989-04-03 1993-11-30 Glenn Roy N-(sulfomethyl)-N'arylureas
US4994490A (en) * 1989-04-03 1991-02-19 The Nutrasweet Company Novel N-(sulfomethyl)-N'-arylureas
FR2653303B1 (fr) * 1989-10-24 1992-09-18 Noffre Claude Agents edulcorants de grande stabilite derivant des acides l-aspartique et l-glutamique n-hydrocarbones 1-oxo-2-ramifies.
KR927003625A (ko) * 1990-02-09 1992-12-18 미셀 모르뱅 N-페닐-n-아세트아미도 글리신아미드, 제조방법 및 이들을 함유하는 약물
FR2697844B1 (fr) * 1992-11-12 1995-01-27 Claude Nofre Nouveaux composés dérivés de dipeptides ou d'analogues dipeptidiques utiles comme agents édulcorants, leur procédé de préparation.
FR2719590B1 (fr) * 1994-05-09 1996-07-26 Claude Nofre Procédé perfectionné de préparation d'un composé dérivé de l'aspartame utile comme agent édulcorant.
AU4891396A (en) * 1995-03-14 1996-10-02 Daiichi Pharmaceutical Co., Ltd. Aminophenol derivatives
PE20000415A1 (es) * 1998-04-08 2000-05-21 Smithkline Beecham Corp Compuestos calciliticos
RU2179979C1 (ru) * 1998-04-09 2002-02-27 Адзиномото Ко., Инк. Сложноэфирные производные аспартилдипептидов и подслащивающие вещества
PL194958B1 (pl) * 1998-06-05 2007-07-31 Wrigley W M Jun Co Sposób wytwarzania gumy do żucia zawierającej fizycznie zmodyfikowaną N-podstawioną pochodną aspartamu o kontrolowanej szybkości uwalniania
US6692778B2 (en) * 1998-06-05 2004-02-17 Wm. Wrigley Jr. Company Method of controlling release of N-substituted derivatives of aspartame in chewing gum
OA11695A (en) * 1998-06-26 2005-01-13 Ajinomoto Kk Novel aspartyl dipeptide ester derivatives and sweeteners.
OA11654A (en) 1998-09-18 2004-12-08 Ajinomoto Kk N-alkylaspartyldipeptide ester derivatives and sweeteners.
US20030018203A1 (en) * 2002-07-17 2003-01-23 Largo Maria Amparo Calcilytic compounds
AR030684A1 (es) * 2000-01-24 2003-09-03 Smithkline Beecham Corp Compuestos calciliticos, uso de dichos compuestos en la manufactura de medicamentos, e intermediarios utiles en la preparacion de dichos compuestos
AR046078A1 (es) 2003-08-06 2005-11-23 Senomyx Inc Nuevos sabores, modificadores de sabores, sustancias gustativas, mejoradores de gusto, sustancias gustativas y/o mejoradoras del gusto umani o dulce y uso de los mismos.
US20060045953A1 (en) * 2004-08-06 2006-03-02 Catherine Tachdjian Aromatic amides and ureas and their uses as sweet and/or umami flavor modifiers, tastants and taste enhancers
EP1855548A2 (en) * 2005-02-04 2007-11-21 Senomyx, Inc. Molecules comprising linked organic moieties as flavor modifiers for comestibles compositions
JP4734346B2 (ja) * 2005-02-04 2011-07-27 セノミックス インコーポレイテッド 連結ヘテロアリール部分を含む化合物、ならびに食用組成物のための新規なうまみフレーバー改変剤、味物質および味覚増強剤としての使用
TW200715993A (en) * 2005-06-15 2007-05-01 Senomyx Inc Bis-aromatic amides and their uses as sweet flavor modifiers, tastants, and taste enhancers
US8435587B2 (en) * 2005-11-23 2013-05-07 The Coca-Cola Company High-potency sweetener composition with long-chain primary aliphatic saturated alcohol and compositions sweetened therewith
US20070116839A1 (en) * 2005-11-23 2007-05-24 The Coca-Cola Company High-Potency Sweetener Composition With C-Reactive Protein Reducing Substance and Compositions Sweetened Therewith
US9101160B2 (en) * 2005-11-23 2015-08-11 The Coca-Cola Company Condiments with high-potency sweetener
US8367138B2 (en) * 2005-11-23 2013-02-05 The Coca-Cola Company Dairy composition with high-potency sweetener
US8940350B2 (en) * 2005-11-23 2015-01-27 The Coca-Cola Company Cereal compositions comprising high-potency sweeteners
US20070116800A1 (en) * 2005-11-23 2007-05-24 The Coca-Cola Company Chewing Gum with High-Potency Sweetener
US8940351B2 (en) * 2005-11-23 2015-01-27 The Coca-Cola Company Baked goods comprising high-potency sweetener
EP1971228A1 (en) * 2005-11-23 2008-09-24 The Coca-Cola Company Natural high-potency sweetener compositions with improved temporal profile and/or flavor profile, methods for their formulation, and uses
US20070116829A1 (en) * 2005-11-23 2007-05-24 The Coca-Cola Company Pharmaceutical Composition with High-Potency Sweetener
US8945652B2 (en) * 2005-11-23 2015-02-03 The Coca-Cola Company High-potency sweetener for weight management and compositions sweetened therewith
US20070116833A1 (en) * 2005-11-23 2007-05-24 The Coca-Cola Company High-Potency Sweetener Composition with Calcium and Compositions Sweetened Therewith
US8435588B2 (en) * 2005-11-23 2013-05-07 The Coca-Cola Company High-potency sweetener composition with an anti-inflammatory agent and compositions sweetened therewith
US8512789B2 (en) * 2005-11-23 2013-08-20 The Coca-Cola Company High-potency sweetener composition with dietary fiber and compositions sweetened therewith
US8524303B2 (en) * 2005-11-23 2013-09-03 The Coca-Cola Company High-potency sweetener composition with phytosterol and compositions sweetened therewith
US8524304B2 (en) * 2005-11-23 2013-09-03 The Coca-Cola Company High-potency sweetener composition with probiotics/prebiotics and compositions sweetened therewith
US8377491B2 (en) * 2005-11-23 2013-02-19 The Coca-Cola Company High-potency sweetener composition with vitamin and compositions sweetened therewith
ES2640453T3 (es) 2006-04-21 2017-11-03 Senomyx, Inc. Procesos para preparar composiciones saborizantes sólidas
US8017168B2 (en) * 2006-11-02 2011-09-13 The Coca-Cola Company High-potency sweetener composition with rubisco protein, rubiscolin, rubiscolin derivatives, ace inhibitory peptides, and combinations thereof, and compositions sweetened therewith
WO2009063804A1 (ja) 2007-11-16 2009-05-22 Kaneka Corporation Ｎ－カルバモイル－ｔｅｒｔ－ロイシンの製造法
CN106518742B (zh) 2011-10-26 2020-01-21 阿勒根公司 作为甲酰肽受体样-1(fprl-1)受体调节剂的n-脲取代的氨基酸的酰胺衍生物
WO2015009545A1 (en) 2013-07-16 2015-01-22 Allergan, Inc. Derivatives of n-urea substituted amino acids as formyl peptide receptor modulators
CA2948876A1 (en) 2014-05-21 2015-11-26 Allergan, Inc. Imidazole derivatives as formyl peptide receptor modulators

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3492131A (en) * 1966-04-18 1970-01-27 Searle & Co Peptide sweetening agents
US3800046A (en) * 1967-04-17 1974-03-26 Searle & Co Artificially sweetened consumable products
GB1258248A (enExample) * 1968-07-17 1971-12-22
US3642491A (en) * 1970-01-12 1972-02-15 Searle & Co Artificially sweetened consumable products
CA1027113A (en) * 1973-04-02 1978-02-28 General Foods Corporation Sweetener solution containing saccharin and aspartane
NL8005006A (nl) * 1980-09-04 1982-04-01 Stamicarbon Dipeptide-zoetstof.

Also Published As

Publication number Publication date
PT77351A (fr) 1983-10-01
ZA836892B (en) 1984-05-30
US4645678A (en) 1987-02-24
EP0107597B1 (fr) 1986-02-26
IL69733A0 (en) 1983-12-30
ATE18236T1 (de) 1986-03-15
DK424783A (da) 1984-03-18
AU1916583A (en) 1984-03-22
AU562104B2 (en) 1987-05-28
CA1244007A (fr) 1988-11-01
ES8406423A1 (es) 1984-07-01
DE3362324D1 (en) 1986-04-03
EP0107597A1 (fr) 1984-05-02
NO158418C (no) 1988-09-07
NZ205616A (en) 1986-03-14
PT77351B (fr) 1986-03-18
JPS5973559A (ja) 1984-04-25
NO833338L (no) 1984-03-19
GR81273B (enExample) 1984-12-11
ES525680A0 (es) 1984-07-01
NO158418B (no) 1988-05-30
FR2533210A1 (fr) 1984-03-23
DK424783D0 (da) 1983-09-16

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Legal Events

Date Code Title Description
EM Correction of a material error concerning inscription in the national patent register
TP Transmission of property
ST Notification of lapse