FR2533210B1 - - Google Patents

Info

Publication number
FR2533210B1
FR2533210B1 FR8215832A FR8215832A FR2533210B1 FR 2533210 B1 FR2533210 B1 FR 2533210B1 FR 8215832 A FR8215832 A FR 8215832A FR 8215832 A FR8215832 A FR 8215832A FR 2533210 B1 FR2533210 B1 FR 2533210B1
Authority
FR
France
Prior art keywords
group
lone
carbon atoms
electron pair
pair donor
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
FR8215832A
Other languages
English (en)
French (fr)
Other versions
FR2533210A1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Universite Claude Bernard Lyon 1
Original Assignee
Universite Claude Bernard Lyon 1
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Universite Claude Bernard Lyon 1 filed Critical Universite Claude Bernard Lyon 1
Priority to FR8215832A priority Critical patent/FR2533210A1/fr
Priority to JP58170541A priority patent/JPS5973559A/ja
Priority to GR72445A priority patent/GR81273B/el
Priority to DE8383420149T priority patent/DE3362324D1/de
Priority to US06/532,499 priority patent/US4645678A/en
Priority to AU19165/83A priority patent/AU562104B2/en
Priority to IL69733A priority patent/IL69733A0/xx
Priority to AT83420149T priority patent/ATE18236T1/de
Priority to EP83420149A priority patent/EP0107597B1/fr
Priority to PT77351A priority patent/PT77351B/pt
Priority to ES525680A priority patent/ES525680A0/es
Priority to ZA836892A priority patent/ZA836892B/xx
Priority to NO833338A priority patent/NO158418C/no
Priority to CA000436906A priority patent/CA1244007A/fr
Priority to NZ205616A priority patent/NZ205616A/en
Priority to DK424783A priority patent/DK424783A/da
Publication of FR2533210A1 publication Critical patent/FR2533210A1/fr
Application granted granted Critical
Publication of FR2533210B1 publication Critical patent/FR2533210B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06104—Dipeptides with the first amino acid being acidic
    • C07K5/06113—Asp- or Asn-amino acid
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L27/00—Spices; Flavouring agents or condiments; Artificial sweetening agents; Table salts; Dietetic salt substitutes; Preparation or treatment thereof
    • A23L27/30—Artificial sweetening agents
    • A23L27/31—Artificial sweetening agents containing amino acids, nucleotides, peptides or derivatives
    • A23L27/32—Artificial sweetening agents containing amino acids, nucleotides, peptides or derivatives containing dipeptides or derivatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06104—Dipeptides with the first amino acid being acidic
    • C07K5/06113—Asp- or Asn-amino acid
    • C07K5/06121—Asp- or Asn-amino acid the second amino acid being aromatic or cycloaliphatic
    • C07K5/0613—Aspartame

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Engineering & Computer Science (AREA)
  • Nutrition Science (AREA)
  • Seasonings (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Tea And Coffee (AREA)
  • Indole Compounds (AREA)
  • Ultra Sonic Daignosis Equipment (AREA)
  • Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)
  • Oscillators With Electromechanical Resonators (AREA)
  • Jellies, Jams, And Syrups (AREA)
  • General Preparation And Processing Of Foods (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrrole Compounds (AREA)
FR8215832A 1982-09-17 1982-09-17 Edulcorants de synthese Granted FR2533210A1 (fr)

Priority Applications (16)

Application Number Priority Date Filing Date Title
FR8215832A FR2533210A1 (fr) 1982-09-17 1982-09-17 Edulcorants de synthese
JP58170541A JPS5973559A (ja) 1982-09-17 1983-09-14 合成甘味物質
DE8383420149T DE3362324D1 (en) 1982-09-17 1983-09-15 Chemical compounds and their use as sweetening agents
US06/532,499 US4645678A (en) 1982-09-17 1983-09-15 Sweetening agents
AU19165/83A AU562104B2 (en) 1982-09-17 1983-09-15 Substituted ureas and thioureas as sweeteners
IL69733A IL69733A0 (en) 1982-09-17 1983-09-15 Phenylurea derivatives and their use as sweetening agents
AT83420149T ATE18236T1 (de) 1982-09-17 1983-09-15 Chemische verbindungen und verwendung als suessstoff.
EP83420149A EP0107597B1 (fr) 1982-09-17 1983-09-15 Composés chimiques et utilisation comme édulcorants
GR72445A GR81273B (enExample) 1982-09-17 1983-09-15
ES525680A ES525680A0 (es) 1982-09-17 1983-09-16 Procedimiento para la preparacion de derivados de amino acidos, de efecto edulcorante
PT77351A PT77351B (fr) 1982-09-17 1983-09-16 Procede pour la preparation de derives d'aminoacides ayant un effet edulcorant
ZA836892A ZA836892B (en) 1982-09-17 1983-09-16 Synthetic sweeteners
NO833338A NO158418C (no) 1982-09-17 1983-09-16 Soetningsmidler.
CA000436906A CA1244007A (fr) 1982-09-17 1983-09-16 Procede pour la preparation d'edulcorants de preparation synthese, les edulcorants ainsi obtenus ainsi que leurs applications a la preparation de substances consommables sucrees
NZ205616A NZ205616A (en) 1982-09-17 1983-09-16 Synthetic sweetening compounds and compositions
DK424783A DK424783A (da) 1982-09-17 1983-09-16 Soedemidler

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8215832A FR2533210A1 (fr) 1982-09-17 1982-09-17 Edulcorants de synthese

Publications (2)

Publication Number Publication Date
FR2533210A1 FR2533210A1 (fr) 1984-03-23
FR2533210B1 true FR2533210B1 (enExample) 1984-11-23

Family

ID=9277590

Family Applications (1)

Application Number Title Priority Date Filing Date
FR8215832A Granted FR2533210A1 (fr) 1982-09-17 1982-09-17 Edulcorants de synthese

Country Status (16)

Country Link
US (1) US4645678A (enExample)
EP (1) EP0107597B1 (enExample)
JP (1) JPS5973559A (enExample)
AT (1) ATE18236T1 (enExample)
AU (1) AU562104B2 (enExample)
CA (1) CA1244007A (enExample)
DE (1) DE3362324D1 (enExample)
DK (1) DK424783A (enExample)
ES (1) ES525680A0 (enExample)
FR (1) FR2533210A1 (enExample)
GR (1) GR81273B (enExample)
IL (1) IL69733A0 (enExample)
NO (1) NO158418C (enExample)
NZ (1) NZ205616A (enExample)
PT (1) PT77351B (enExample)
ZA (1) ZA836892B (enExample)

Families Citing this family (59)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2575163B1 (fr) * 1984-12-20 1987-03-20 Sanofi Sa Tri- et tetrapeptides reduits inhibiteurs de la secretion gastrique, procede d'obtention et compositions pharmaceutiques les contenant
US4833128A (en) * 1984-12-28 1989-05-23 Neil Solomon Dietary supplement
FR2579201B1 (fr) * 1985-03-19 1987-05-07 Bernard Lyon I Universite Clau Composes chimiques perfectionnes, utilisation comme agents edulcorants et compositions contenant de tels agents
FR2579202B1 (fr) * 1985-03-19 1988-04-29 Univ Claude Bernard Lyon Nouveaux composes chimiques, utilisation comme agents edulcorants et compositions contenant de tels agents
US4921939A (en) * 1985-03-19 1990-05-01 Universite Claude Bernard -Lyon 1 Sweetening agents
FR2606404B2 (fr) * 1986-04-10 1991-11-22 Univ Claude Bernard Lyon Nouveaux composes chimiques derivant de l'acide phenylguanidinoacetique et leur utilisation comme agents edulcorants
FR2608379B1 (fr) * 1986-12-23 1989-03-24 Univ Claude Bernard Lyon Agents edulcorants derives des acides n-phenylguanidinoacetique et n-phenylethanamidinoacetique, procede pour edulcorer des produits divers, et compositions contenant de tels agents edulcorants
JPS61260052A (ja) * 1985-05-14 1986-11-18 Ajinomoto Co Inc 新規アミノ酸誘導体および甘味剤
KR870008526A (ko) * 1986-03-13 1987-10-19 원본미기재 감미료 및 그 제조방법
US4818899A (en) * 1986-12-03 1989-04-04 Minnesota Mining And Manufacturing Company Second harmonic generation by carbamic acid derivatives
FR2609603B1 (fr) * 1987-01-15 1989-03-24 Univ Claude Bernard Lyon Agents edulcorants derives des acides guanidinoacetique et ethanamidinoacetique, procede pour edulcorer des produits divers, et compositions contenant de tels agents edulcorants
WO1989000563A1 (en) * 1987-07-17 1989-01-26 The Nutrasweet Company High potency sweetening agents
US4900740A (en) * 1987-10-02 1990-02-13 The Nutrasweet Company N,N'-disubstituted guanidines containing a carboxyl or a tetrazolyl moiety
FR2624699B1 (fr) * 1987-12-18 1990-04-13 Bernard Lyon I Universite Clau Derives heterocycliques de n-carbamoyl-, n-thiocarbamoyl- ou n-amidino-glycine ou beta-alanine utiles comme agents edulcorants
FR2624698A1 (fr) * 1987-12-18 1989-06-23 Bernard Lyon I Universite Clau Derives heterocycliques de n-carbamoyl-, n-thiocarbamoyl- ou n-amidino-aminomalonyl ou aminosuccinyl amides utiles comme agents edulcorants
FR2630304B1 (fr) * 1988-04-22 1990-08-31 Bernard Lyon I Universite Clau Derives n-hydrocarbones des acides aspartique et glutamique alpha-monoamides utiles comme agents edulcorants
JP2791156B2 (ja) * 1988-08-23 1998-08-27 ザ ヌトラスウィート カンパニー 強力甘味料としての置換アリール尿素
US4994490A (en) * 1989-04-03 1991-02-19 The Nutrasweet Company Novel N-(sulfomethyl)-N'-arylureas
US5266717A (en) * 1989-04-03 1993-11-30 Glenn Roy N-(sulfomethyl)-N'arylureas
FR2653303B1 (fr) * 1989-10-24 1992-09-18 Noffre Claude Agents edulcorants de grande stabilite derivant des acides l-aspartique et l-glutamique n-hydrocarbones 1-oxo-2-ramifies.
KR927003625A (ko) * 1990-02-09 1992-12-18 미셀 모르뱅 N-페닐-n-아세트아미도 글리신아미드, 제조방법 및 이들을 함유하는 약물
FR2697844B1 (fr) * 1992-11-12 1995-01-27 Claude Nofre Nouveaux composés dérivés de dipeptides ou d'analogues dipeptidiques utiles comme agents édulcorants, leur procédé de préparation.
FR2719590B1 (fr) * 1994-05-09 1996-07-26 Claude Nofre Procédé perfectionné de préparation d'un composé dérivé de l'aspartame utile comme agent édulcorant.
EP0985660A1 (en) * 1995-03-14 2000-03-15 Daiichi Pharmaceutical Co., Ltd. Aminophenol derivatives
AR018177A1 (es) * 1998-04-08 2001-10-31 Smithkline Beecham Corp Compuestos calciliticos, una composicion farmaceutica que los comprende y el uso de los mismos para la manufactura de un medicamento.
ES2299252T3 (es) * 1998-04-09 2008-05-16 Ajinomoto Co., Inc. Derivados del ester del dipeptido de aspartilo y edulcorantes.
US6692778B2 (en) * 1998-06-05 2004-02-17 Wm. Wrigley Jr. Company Method of controlling release of N-substituted derivatives of aspartame in chewing gum
BR9815887A (pt) * 1998-06-05 2001-10-23 Wrigley W M Jun Co Método de controle de liberação de derivados de aspartame n-substituìdos em goma de mascar e goma assim produzida
KR100631306B1 (ko) * 1998-06-26 2006-10-09 아지노모토 가부시키가이샤 아스파르틸 디펩타이드 에스테르 유도체 및 이를 함유하는 감미제
CA2344314A1 (en) * 1998-09-18 2000-03-30 Ajinomoto Co., Inc. N-alkylaspartyl dipeptide ester derivative and sweetening agent
AR030684A1 (es) * 2000-01-24 2003-09-03 Smithkline Beecham Corp Compuestos calciliticos, uso de dichos compuestos en la manufactura de medicamentos, e intermediarios utiles en la preparacion de dichos compuestos
US20030018203A1 (en) * 2002-07-17 2003-01-23 Largo Maria Amparo Calcilytic compounds
CA2900181C (en) * 2003-08-06 2019-01-29 Catherine Tachdjian Novel flavors, flavor modifiers, tastants, taste enhancers, umami or sweet tastants, and/or enhancers and use thereof
US20060045953A1 (en) * 2004-08-06 2006-03-02 Catherine Tachdjian Aromatic amides and ureas and their uses as sweet and/or umami flavor modifiers, tastants and taste enhancers
US8968708B2 (en) 2005-02-04 2015-03-03 Senomyx, Inc. Compounds comprising linked heteroaryl moieties and their use as novel umami flavor modifiers, tastants and taste enhancers for comestible compositions
US20060257543A1 (en) * 2005-02-04 2006-11-16 Catherine Tachdjian Molecules comprising linked organic moieties as flavor modifiers for comestible compositions
AR055329A1 (es) * 2005-06-15 2007-08-15 Senomyx Inc Amidas bis-aromaticas y sus usos como modificadores de sabor dulce, saborizantes, y realzadores de sabor
US8367138B2 (en) * 2005-11-23 2013-02-05 The Coca-Cola Company Dairy composition with high-potency sweetener
US8377491B2 (en) * 2005-11-23 2013-02-19 The Coca-Cola Company High-potency sweetener composition with vitamin and compositions sweetened therewith
US8524304B2 (en) * 2005-11-23 2013-09-03 The Coca-Cola Company High-potency sweetener composition with probiotics/prebiotics and compositions sweetened therewith
US8524303B2 (en) * 2005-11-23 2013-09-03 The Coca-Cola Company High-potency sweetener composition with phytosterol and compositions sweetened therewith
US8945652B2 (en) * 2005-11-23 2015-02-03 The Coca-Cola Company High-potency sweetener for weight management and compositions sweetened therewith
US8940351B2 (en) * 2005-11-23 2015-01-27 The Coca-Cola Company Baked goods comprising high-potency sweetener
MX2008006583A (es) * 2005-11-23 2008-05-31 Coca Cola Co Composiciones de edulcorante natural de alta potencia, con perfil de sabor y/o perfil temporal mejorado, metodos para su formulacion, y usos
US8512789B2 (en) * 2005-11-23 2013-08-20 The Coca-Cola Company High-potency sweetener composition with dietary fiber and compositions sweetened therewith
US20070116800A1 (en) * 2005-11-23 2007-05-24 The Coca-Cola Company Chewing Gum with High-Potency Sweetener
US20070116833A1 (en) * 2005-11-23 2007-05-24 The Coca-Cola Company High-Potency Sweetener Composition with Calcium and Compositions Sweetened Therewith
US8435588B2 (en) * 2005-11-23 2013-05-07 The Coca-Cola Company High-potency sweetener composition with an anti-inflammatory agent and compositions sweetened therewith
US20070116839A1 (en) * 2005-11-23 2007-05-24 The Coca-Cola Company High-Potency Sweetener Composition With C-Reactive Protein Reducing Substance and Compositions Sweetened Therewith
US9101160B2 (en) * 2005-11-23 2015-08-11 The Coca-Cola Company Condiments with high-potency sweetener
US8940350B2 (en) * 2005-11-23 2015-01-27 The Coca-Cola Company Cereal compositions comprising high-potency sweeteners
US8435587B2 (en) * 2005-11-23 2013-05-07 The Coca-Cola Company High-potency sweetener composition with long-chain primary aliphatic saturated alcohol and compositions sweetened therewith
US20070116829A1 (en) * 2005-11-23 2007-05-24 The Coca-Cola Company Pharmaceutical Composition with High-Potency Sweetener
EP3235811B1 (en) 2006-04-21 2018-07-25 Senomyx, Inc. Process of preparing oxalamides
US8017168B2 (en) * 2006-11-02 2011-09-13 The Coca-Cola Company High-potency sweetener composition with rubisco protein, rubiscolin, rubiscolin derivatives, ace inhibitory peptides, and combinations thereof, and compositions sweetened therewith
JP5647790B2 (ja) 2007-11-16 2015-01-07 株式会社カネカ Ｎ−カルバモイル−ｔｅｒｔ−ロイシンの製造法
PH12019500171B1 (en) 2011-10-26 2022-08-12 Allergan Inc Amide derivatives of n-urea substituted amino acids as formyl peptide receptor like-1 (fprl-1) receptor modulators
CA2917811C (en) 2013-07-16 2021-08-31 Allergan, Inc. Derivatives of n-urea substituted amino acids as formyl peptide receptor modulators
US10301269B2 (en) 2014-05-21 2019-05-28 Allergan, Inc. Imidazole derivatives as formyl peptide receptor modulators

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3492131A (en) * 1966-04-18 1970-01-27 Searle & Co Peptide sweetening agents
US3800046A (en) * 1967-04-17 1974-03-26 Searle & Co Artificially sweetened consumable products
GB1258248A (enExample) * 1968-07-17 1971-12-22
US3642491A (en) * 1970-01-12 1972-02-15 Searle & Co Artificially sweetened consumable products
CA1027113A (en) * 1973-04-02 1978-02-28 General Foods Corporation Sweetener solution containing saccharin and aspartane
NL8005006A (nl) * 1980-09-04 1982-04-01 Stamicarbon Dipeptide-zoetstof.

Also Published As

Publication number Publication date
NO158418C (no) 1988-09-07
NO833338L (no) 1984-03-19
DE3362324D1 (en) 1986-04-03
US4645678A (en) 1987-02-24
CA1244007A (fr) 1988-11-01
ES8406423A1 (es) 1984-07-01
FR2533210A1 (fr) 1984-03-23
EP0107597A1 (fr) 1984-05-02
NO158418B (no) 1988-05-30
PT77351B (fr) 1986-03-18
AU1916583A (en) 1984-03-22
ZA836892B (en) 1984-05-30
NZ205616A (en) 1986-03-14
ATE18236T1 (de) 1986-03-15
AU562104B2 (en) 1987-05-28
GR81273B (enExample) 1984-12-11
DK424783A (da) 1984-03-18
ES525680A0 (es) 1984-07-01
EP0107597B1 (fr) 1986-02-26
JPS5973559A (ja) 1984-04-25
IL69733A0 (en) 1983-12-30
PT77351A (fr) 1983-10-01
DK424783D0 (da) 1983-09-16

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Legal Events

Date Code Title Description
EM Correction of a material error concerning inscription in the national patent register
TP Transmission of property
ST Notification of lapse