FR2519023B1 - Procede microbiologique pour preparer de la nebramycine-2, de la nebramycine-5' et de la nebramycine-4 - Google Patents

Procede microbiologique pour preparer de la nebramycine-2, de la nebramycine-5' et de la nebramycine-4

Info

Publication number
FR2519023B1
FR2519023B1 FR8221803A FR8221803A FR2519023B1 FR 2519023 B1 FR2519023 B1 FR 2519023B1 FR 8221803 A FR8221803 A FR 8221803A FR 8221803 A FR8221803 A FR 8221803A FR 2519023 B1 FR2519023 B1 FR 2519023B1
Authority
FR
France
Prior art keywords
nebramycin
preparation
microbiological process
microbiological
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
FR8221803A
Other languages
English (en)
French (fr)
Other versions
FR2519023A1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Teva Pharmaceutical Works PLC
Original Assignee
Biogal Gyogyszergyar Rt
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biogal Gyogyszergyar Rt filed Critical Biogal Gyogyszergyar Rt
Publication of FR2519023A1 publication Critical patent/FR2519023A1/fr
Application granted granted Critical
Publication of FR2519023B1 publication Critical patent/FR2519023B1/fr
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00Preparation of compounds containing saccharide radicals
    • C12P19/44Preparation of O-glycosides, e.g. glucosides
    • C12P19/46Preparation of O-glycosides, e.g. glucosides having an oxygen atom of the saccharide radical bound to a cyclohexyl radical, e.g. kasugamycin
    • C12P19/48Preparation of O-glycosides, e.g. glucosides having an oxygen atom of the saccharide radical bound to a cyclohexyl radical, e.g. kasugamycin the cyclohexyl radical being substituted by two or more nitrogen atoms, e.g. destomycin, neamin
    • C12P19/485Having two saccharide radicals bound through only oxygen to non-adjacent ring carbons of the cyclohexyl radical, e.g. gentamycin, kanamycin, sisomycin, verdamycin, mutamycin, tobramycin, nebramycin, antibiotics 66-40B, 66-40D, XK-62-2, 66-40, G-418, G-52
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20Bacteria; Culture media therefor
    • C12N1/205Bacterial isolates
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00Preparation of compounds containing saccharide radicals
    • C12P19/44Preparation of O-glycosides, e.g. glucosides
    • C12P19/46Preparation of O-glycosides, e.g. glucosides having an oxygen atom of the saccharide radical bound to a cyclohexyl radical, e.g. kasugamycin
    • C12P19/48Preparation of O-glycosides, e.g. glucosides having an oxygen atom of the saccharide radical bound to a cyclohexyl radical, e.g. kasugamycin the cyclohexyl radical being substituted by two or more nitrogen atoms, e.g. destomycin, neamin
    • C12P19/50Preparation of O-glycosides, e.g. glucosides having an oxygen atom of the saccharide radical bound to a cyclohexyl radical, e.g. kasugamycin the cyclohexyl radical being substituted by two or more nitrogen atoms, e.g. destomycin, neamin having two saccharide radicals bound through only oxygen to adjacent ring carbon atoms of the cyclohexyl radical, e.g. ambutyrosin, ribostamycin
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12RINDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00Microorganisms ; Processes using microorganisms
    • C12R2001/01Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/465Streptomyces

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Medicinal Chemistry (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
FR8221803A 1981-12-28 1982-12-27 Procede microbiologique pour preparer de la nebramycine-2, de la nebramycine-5' et de la nebramycine-4 Expired FR2519023B1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU813954A HU190680B (en) 1981-12-28 1981-12-28 Process for preparing 6''-0-carbamoyl-tobramycin microbiologically

Publications (2)

Publication Number Publication Date
FR2519023A1 FR2519023A1 (fr) 1983-07-01
FR2519023B1 true FR2519023B1 (fr) 1985-10-25

Family

ID=10966213

Family Applications (1)

Application Number Title Priority Date Filing Date
FR8221803A Expired FR2519023B1 (fr) 1981-12-28 1982-12-27 Procede microbiologique pour preparer de la nebramycine-2, de la nebramycine-5' et de la nebramycine-4

Country Status (9)

Country Link
AT (1) AT379171B (de)
BE (1) BE895455A (de)
CH (2) CH658072A5 (de)
DE (1) DE3248420A1 (de)
FI (1) FI74995C (de)
FR (1) FR2519023B1 (de)
GB (1) GB2114978B (de)
HU (1) HU190680B (de)
NL (1) NL8205011A (de)

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3691279A (en) * 1970-04-15 1972-09-12 Lilly Co Eli Antibiotic nebramycin and preparation thereof
US3853709A (en) * 1970-10-26 1974-12-10 Lilly Co Eli Process for preparing nebramycin factors ii and vii
US4032404A (en) * 1976-07-14 1977-06-28 Bristol-Myers Company Fermentation process for producing apramycin and nebramycin factor V'

Also Published As

Publication number Publication date
FR2519023A1 (fr) 1983-07-01
GB2114978B (en) 1985-09-11
CH657374A5 (de) 1986-08-29
CH658072A5 (de) 1986-10-15
BE895455A (fr) 1983-06-23
NL8205011A (nl) 1983-07-18
ATA470482A (de) 1985-04-15
FI824483A0 (fi) 1982-12-28
AT379171B (de) 1985-11-25
GB2114978A (en) 1983-09-01
FI74995B (fi) 1987-12-31
DE3248420C2 (de) 1990-11-08
DE3248420A1 (de) 1983-07-21
FI824483L (fi) 1983-06-29
FI74995C (fi) 1988-04-11
HU190680B (en) 1986-10-28

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