FR2519023B1 - MICROBIOLOGICAL PROCESS FOR THE PREPARATION OF NEBRAMYCIN-2, NEBRAMYCIN-5 'AND NEBRAMYCIN-4 - Google Patents
MICROBIOLOGICAL PROCESS FOR THE PREPARATION OF NEBRAMYCIN-2, NEBRAMYCIN-5 'AND NEBRAMYCIN-4Info
- Publication number
- FR2519023B1 FR2519023B1 FR8221803A FR8221803A FR2519023B1 FR 2519023 B1 FR2519023 B1 FR 2519023B1 FR 8221803 A FR8221803 A FR 8221803A FR 8221803 A FR8221803 A FR 8221803A FR 2519023 B1 FR2519023 B1 FR 2519023B1
- Authority
- FR
- France
- Prior art keywords
- nebramycin
- preparation
- microbiological process
- microbiological
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- YPPFEJHOHNPKLT-UHFFFAOYSA-N Cuauhtemon-3-(2,3-epoxy-2,3-dihydroangelicat Natural products NC1CC(O)C(CN)OC1OC1C(O)C(OC2C(C(N)C(O)C(COC(N)=O)O2)O)C(N)CC1N YPPFEJHOHNPKLT-UHFFFAOYSA-N 0.000 title 1
- XCSTZNJIQFIVPE-FQSMHNGLSA-N Nebramycin IV Chemical compound N[C@@H]1[C@@H](O)[C@H](O)[C@@H](CN)O[C@@H]1O[C@H]1[C@H](O)[C@@H](O[C@@H]2[C@@H]([C@@H](N)[C@H](O)[C@@H](COC(N)=O)O2)O)[C@H](N)C[C@@H]1N XCSTZNJIQFIVPE-FQSMHNGLSA-N 0.000 title 1
- 230000002906 microbiologic effect Effects 0.000 title 1
- YPPFEJHOHNPKLT-PBSUHMDJSA-N nebramycin 5' Chemical compound N[C@@H]1C[C@H](O)[C@@H](CN)O[C@@H]1O[C@H]1[C@H](O)[C@@H](O[C@@H]2[C@@H]([C@@H](N)[C@H](O)[C@@H](COC(N)=O)O2)O)[C@H](N)C[C@@H]1N YPPFEJHOHNPKLT-PBSUHMDJSA-N 0.000 title 1
- SQJLXMDBYVXCEL-UHFFFAOYSA-N nebramycin 5' Natural products C1CC(C)=CCCC(=C)C2COC(=O)C(=CCC=C(C)C)C21 SQJLXMDBYVXCEL-UHFFFAOYSA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/44—Preparation of O-glycosides, e.g. glucosides
- C12P19/46—Preparation of O-glycosides, e.g. glucosides having an oxygen atom of the saccharide radical bound to a cyclohexyl radical, e.g. kasugamycin
- C12P19/48—Preparation of O-glycosides, e.g. glucosides having an oxygen atom of the saccharide radical bound to a cyclohexyl radical, e.g. kasugamycin the cyclohexyl radical being substituted by two or more nitrogen atoms, e.g. destomycin, neamin
- C12P19/485—Having two saccharide radicals bound through only oxygen to non-adjacent ring carbons of the cyclohexyl radical, e.g. gentamycin, kanamycin, sisomycin, verdamycin, mutamycin, tobramycin, nebramycin, antibiotics 66-40B, 66-40D, XK-62-2, 66-40, G-418, G-52
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
- C12N1/205—Bacterial isolates
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/44—Preparation of O-glycosides, e.g. glucosides
- C12P19/46—Preparation of O-glycosides, e.g. glucosides having an oxygen atom of the saccharide radical bound to a cyclohexyl radical, e.g. kasugamycin
- C12P19/48—Preparation of O-glycosides, e.g. glucosides having an oxygen atom of the saccharide radical bound to a cyclohexyl radical, e.g. kasugamycin the cyclohexyl radical being substituted by two or more nitrogen atoms, e.g. destomycin, neamin
- C12P19/50—Preparation of O-glycosides, e.g. glucosides having an oxygen atom of the saccharide radical bound to a cyclohexyl radical, e.g. kasugamycin the cyclohexyl radical being substituted by two or more nitrogen atoms, e.g. destomycin, neamin having two saccharide radicals bound through only oxygen to adjacent ring carbon atoms of the cyclohexyl radical, e.g. ambutyrosin, ribostamycin
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
- C12R2001/00—Microorganisms ; Processes using microorganisms
- C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
- C12R2001/465—Streptomyces
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| HU813954A HU190680B (en) | 1981-12-28 | 1981-12-28 | Process for preparing 6''-0-carbamoyl-tobramycin microbiologically |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FR2519023A1 FR2519023A1 (en) | 1983-07-01 |
| FR2519023B1 true FR2519023B1 (en) | 1985-10-25 |
Family
ID=10966213
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR8221803A Expired FR2519023B1 (en) | 1981-12-28 | 1982-12-27 | MICROBIOLOGICAL PROCESS FOR THE PREPARATION OF NEBRAMYCIN-2, NEBRAMYCIN-5 'AND NEBRAMYCIN-4 |
Country Status (9)
| Country | Link |
|---|---|
| AT (1) | AT379171B (en) |
| BE (1) | BE895455A (en) |
| CH (2) | CH658072A5 (en) |
| DE (1) | DE3248420A1 (en) |
| FI (1) | FI74995C (en) |
| FR (1) | FR2519023B1 (en) |
| GB (1) | GB2114978B (en) |
| HU (1) | HU190680B (en) |
| NL (1) | NL8205011A (en) |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3691279A (en) * | 1970-04-15 | 1972-09-12 | Lilly Co Eli | Antibiotic nebramycin and preparation thereof |
| US3853709A (en) * | 1970-10-26 | 1974-12-10 | Lilly Co Eli | Process for preparing nebramycin factors ii and vii |
| US4032404A (en) * | 1976-07-14 | 1977-06-28 | Bristol-Myers Company | Fermentation process for producing apramycin and nebramycin factor V' |
-
1981
- 1981-12-28 HU HU813954A patent/HU190680B/en not_active IP Right Cessation
-
1982
- 1982-12-23 BE BE1/10669A patent/BE895455A/en not_active IP Right Cessation
- 1982-12-27 CH CH3108/85A patent/CH658072A5/en not_active IP Right Cessation
- 1982-12-27 CH CH7558/82A patent/CH657374A5/en not_active IP Right Cessation
- 1982-12-27 FR FR8221803A patent/FR2519023B1/en not_active Expired
- 1982-12-28 FI FI824483A patent/FI74995C/en not_active IP Right Cessation
- 1982-12-28 DE DE19823248420 patent/DE3248420A1/en active Granted
- 1982-12-28 AT AT0470482A patent/AT379171B/en not_active IP Right Cessation
- 1982-12-28 NL NL8205011A patent/NL8205011A/en not_active Application Discontinuation
- 1982-12-30 GB GB08236905A patent/GB2114978B/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| DE3248420C2 (en) | 1990-11-08 |
| CH658072A5 (en) | 1986-10-15 |
| GB2114978A (en) | 1983-09-01 |
| AT379171B (en) | 1985-11-25 |
| ATA470482A (en) | 1985-04-15 |
| FI74995C (en) | 1988-04-11 |
| FI824483L (en) | 1983-06-29 |
| CH657374A5 (en) | 1986-08-29 |
| FI824483A0 (en) | 1982-12-28 |
| FI74995B (en) | 1987-12-31 |
| BE895455A (en) | 1983-06-23 |
| HU190680B (en) | 1986-10-28 |
| NL8205011A (en) | 1983-07-18 |
| DE3248420A1 (en) | 1983-07-21 |
| GB2114978B (en) | 1985-09-11 |
| FR2519023A1 (en) | 1983-07-01 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ST | Notification of lapse |