FR2485548A1 - Procede de preparation d'un polymere de structure tridimensionnelle du type polyurethane reticule, produit obtenu selon ce procede et son application en tant qu'agent gonflant, notamment en therapeutique - Google Patents
Procede de preparation d'un polymere de structure tridimensionnelle du type polyurethane reticule, produit obtenu selon ce procede et son application en tant qu'agent gonflant, notamment en therapeutique Download PDFInfo
- Publication number
- FR2485548A1 FR2485548A1 FR8014515A FR8014515A FR2485548A1 FR 2485548 A1 FR2485548 A1 FR 2485548A1 FR 8014515 A FR8014515 A FR 8014515A FR 8014515 A FR8014515 A FR 8014515A FR 2485548 A1 FR2485548 A1 FR 2485548A1
- Authority
- FR
- France
- Prior art keywords
- polyol
- polyurethane
- groups
- polymer
- weight
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 229920000642 polymer Polymers 0.000 title claims abstract description 45
- 239000004814 polyurethane Substances 0.000 title claims abstract description 21
- 229920002635 polyurethane Polymers 0.000 title claims abstract description 21
- 238000000034 method Methods 0.000 title claims description 29
- 239000003795 chemical substances by application Substances 0.000 title claims description 9
- 238000002360 preparation method Methods 0.000 title claims description 4
- 239000003814 drug Substances 0.000 title claims description 3
- 229920005862 polyol Polymers 0.000 claims abstract description 55
- 239000000203 mixture Substances 0.000 claims abstract description 32
- BRLQWZUYTZBJKN-UHFFFAOYSA-N Epichlorohydrin Chemical compound ClCC1CO1 BRLQWZUYTZBJKN-UHFFFAOYSA-N 0.000 claims abstract description 30
- 238000006243 chemical reaction Methods 0.000 claims abstract description 23
- 150000003077 polyols Chemical class 0.000 claims abstract description 19
- 229920000768 polyamine Polymers 0.000 claims abstract description 18
- 229920001228 polyisocyanate Polymers 0.000 claims abstract description 12
- 239000005056 polyisocyanate Substances 0.000 claims abstract description 12
- -1 AMINO Chemical class 0.000 claims abstract description 10
- 239000004604 Blowing Agent Substances 0.000 claims abstract description 3
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 60
- NAQMVNRVTILPCV-UHFFFAOYSA-N hexane-1,6-diamine Chemical compound NCCCCCCN NAQMVNRVTILPCV-UHFFFAOYSA-N 0.000 claims description 39
- ZMXDDKWLCZADIW-UHFFFAOYSA-N N,N-Dimethylformamide Chemical compound CN(C)C=O ZMXDDKWLCZADIW-UHFFFAOYSA-N 0.000 claims description 32
- 238000003756 stirring Methods 0.000 claims description 25
- 125000002887 hydroxy group Chemical group [H]O* 0.000 claims description 20
- 230000008961 swelling Effects 0.000 claims description 20
- 239000002904 solvent Substances 0.000 claims description 16
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 claims description 14
- DVKJHBMWWAPEIU-UHFFFAOYSA-N toluene 2,4-diisocyanate Chemical compound CC1=CC=C(N=C=O)C=C1N=C=O DVKJHBMWWAPEIU-UHFFFAOYSA-N 0.000 claims description 12
- SCYULBFZEHDVBN-UHFFFAOYSA-N 1,1-Dichloroethane Chemical compound CC(Cl)Cl SCYULBFZEHDVBN-UHFFFAOYSA-N 0.000 claims description 11
- 239000000499 gel Substances 0.000 claims description 10
- CSCPPACGZOOCGX-UHFFFAOYSA-N Acetone Chemical compound CC(C)=O CSCPPACGZOOCGX-UHFFFAOYSA-N 0.000 claims description 8
- 239000012429 reaction media Substances 0.000 claims description 8
- 238000001035 drying Methods 0.000 claims description 7
- HEDRZPFGACZZDS-UHFFFAOYSA-N Chloroform Chemical compound ClC(Cl)Cl HEDRZPFGACZZDS-UHFFFAOYSA-N 0.000 claims description 6
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 claims description 6
- WYURNTSHIVDZCO-UHFFFAOYSA-N Tetrahydrofuran Chemical compound C1CCOC1 WYURNTSHIVDZCO-UHFFFAOYSA-N 0.000 claims description 6
- 239000003960 organic solvent Substances 0.000 claims description 6
- 239000000126 substance Substances 0.000 claims description 6
- VZGDMQKNWNREIO-UHFFFAOYSA-N tetrachloromethane Chemical compound ClC(Cl)(Cl)Cl VZGDMQKNWNREIO-UHFFFAOYSA-N 0.000 claims description 6
- 239000003613 bile acid Substances 0.000 claims description 5
- 150000001875 compounds Chemical class 0.000 claims description 5
- FBPFZTCFMRRESA-FSIIMWSLSA-N D-Glucitol Natural products OC[C@H](O)[C@H](O)[C@@H](O)[C@H](O)CO FBPFZTCFMRRESA-FSIIMWSLSA-N 0.000 claims description 4
- FBPFZTCFMRRESA-JGWLITMVSA-N D-glucitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-JGWLITMVSA-N 0.000 claims description 4
- 206010052428 Wound Diseases 0.000 claims description 4
- 208000027418 Wounds and injury Diseases 0.000 claims description 4
- 239000004615 ingredient Substances 0.000 claims description 4
- 239000012299 nitrogen atmosphere Substances 0.000 claims description 4
- 239000000600 sorbitol Substances 0.000 claims description 4
- 125000002947 alkylene group Chemical group 0.000 claims description 3
- 239000002537 cosmetic Substances 0.000 claims description 3
- 239000012458 free base Substances 0.000 claims description 3
- YLQBMQCUIZJEEH-UHFFFAOYSA-N tetrahydrofuran Natural products C=1C=COC=1 YLQBMQCUIZJEEH-UHFFFAOYSA-N 0.000 claims description 3
- UPMLOUAZCHDJJD-UHFFFAOYSA-N 4,4'-Diphenylmethane Diisocyanate Chemical compound C1=CC(N=C=O)=CC=C1CC1=CC=C(N=C=O)C=C1 UPMLOUAZCHDJJD-UHFFFAOYSA-N 0.000 claims description 2
- 125000003277 amino group Chemical group 0.000 claims description 2
- 230000002891 anorexigenic effect Effects 0.000 claims description 2
- 238000009833 condensation Methods 0.000 claims description 2
- 230000005494 condensation Effects 0.000 claims description 2
- FBPFZTCFMRRESA-GUCUJZIJSA-N galactitol Chemical compound OC[C@H](O)[C@@H](O)[C@@H](O)[C@H](O)CO FBPFZTCFMRRESA-GUCUJZIJSA-N 0.000 claims description 2
- 150000004000 hexols Chemical class 0.000 claims description 2
- 230000014759 maintenance of location Effects 0.000 claims description 2
- 230000003020 moisturizing effect Effects 0.000 claims description 2
- WXZMFSXDPGVJKK-UHFFFAOYSA-N pentaerythritol Chemical compound OCC(CO)(CO)CO WXZMFSXDPGVJKK-UHFFFAOYSA-N 0.000 claims description 2
- 150000004072 triols Chemical class 0.000 claims description 2
- 230000001225 therapeutic effect Effects 0.000 claims 3
- 230000002522 swelling effect Effects 0.000 claims 2
- 206010061218 Inflammation Diseases 0.000 claims 1
- 239000004721 Polyphenylene oxide Substances 0.000 claims 1
- 230000003110 anti-inflammatory effect Effects 0.000 claims 1
- 150000004984 aromatic diamines Chemical class 0.000 claims 1
- 125000003710 aryl alkyl group Chemical group 0.000 claims 1
- 230000004054 inflammatory process Effects 0.000 claims 1
- 239000000155 melt Substances 0.000 claims 1
- 229920000570 polyether Polymers 0.000 claims 1
- 238000009987 spinning Methods 0.000 claims 1
- RUELTTOHQODFPA-UHFFFAOYSA-N toluene 2,6-diisocyanate Chemical compound CC1=C(N=C=O)C=CC=C1N=C=O RUELTTOHQODFPA-UHFFFAOYSA-N 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 abstract description 3
- 101001098066 Naja melanoleuca Basic phospholipase A2 1 Proteins 0.000 abstract 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 20
- 235000019441 ethanol Nutrition 0.000 description 12
- 239000012153 distilled water Substances 0.000 description 9
- 239000000843 powder Substances 0.000 description 6
- 239000000835 fiber Substances 0.000 description 5
- 239000002245 particle Substances 0.000 description 5
- 230000000052 comparative effect Effects 0.000 description 4
- RTWNYYOXLSILQN-UHFFFAOYSA-N methanediamine Chemical compound NCN RTWNYYOXLSILQN-UHFFFAOYSA-N 0.000 description 4
- XEKOWRVHYACXOJ-UHFFFAOYSA-N Ethyl acetate Chemical compound CCOC(C)=O XEKOWRVHYACXOJ-UHFFFAOYSA-N 0.000 description 3
- LYCAIKOWRPUZTN-UHFFFAOYSA-N Ethylene glycol Chemical compound OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 description 3
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 description 3
- GOOHAUXETOMSMM-UHFFFAOYSA-N Propylene oxide Chemical compound CC1CO1 GOOHAUXETOMSMM-UHFFFAOYSA-N 0.000 description 3
- 229920001971 elastomer Polymers 0.000 description 3
- 239000000806 elastomer Substances 0.000 description 3
- 238000002844 melting Methods 0.000 description 3
- 230000008018 melting Effects 0.000 description 3
- VLKZOEOYAKHREP-UHFFFAOYSA-N n-Hexane Chemical compound CCCCCC VLKZOEOYAKHREP-UHFFFAOYSA-N 0.000 description 3
- HSINOMROUCMIEA-FGVHQWLLSA-N (2s,4r)-4-[(3r,5s,6r,7r,8s,9s,10s,13r,14s,17r)-6-ethyl-3,7-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1h-cyclopenta[a]phenanthren-17-yl]-2-methylpentanoic acid Chemical compound C([C@@]12C)C[C@@H](O)C[C@H]1[C@@H](CC)[C@@H](O)[C@@H]1[C@@H]2CC[C@]2(C)[C@@H]([C@H](C)C[C@H](C)C(O)=O)CC[C@H]21 HSINOMROUCMIEA-FGVHQWLLSA-N 0.000 description 2
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 description 2
- IAYPIBMASNFSPL-UHFFFAOYSA-N Ethylene oxide Chemical compound C1CO1 IAYPIBMASNFSPL-UHFFFAOYSA-N 0.000 description 2
- GKXVJHDEWHKBFH-UHFFFAOYSA-N [2-(aminomethyl)phenyl]methanamine Chemical compound NCC1=CC=CC=C1CN GKXVJHDEWHKBFH-UHFFFAOYSA-N 0.000 description 2
- 238000010521 absorption reaction Methods 0.000 description 2
- 229940125709 anorectic agent Drugs 0.000 description 2
- 239000002830 appetite depressant Substances 0.000 description 2
- 239000011324 bead Substances 0.000 description 2
- 230000001588 bifunctional effect Effects 0.000 description 2
- HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 description 2
- 230000008602 contraction Effects 0.000 description 2
- 239000013078 crystal Substances 0.000 description 2
- 150000004985 diamines Chemical class 0.000 description 2
- 125000005442 diisocyanate group Chemical group 0.000 description 2
- 239000011521 glass Substances 0.000 description 2
- 229920002521 macromolecule Polymers 0.000 description 2
- 229920001296 polysiloxane Polymers 0.000 description 2
- 230000035484 reaction time Effects 0.000 description 2
- 239000003352 sequestering agent Substances 0.000 description 2
- 239000007787 solid Substances 0.000 description 2
- 238000012360 testing method Methods 0.000 description 2
- 238000012546 transfer Methods 0.000 description 2
- GEYOCULIXLDCMW-UHFFFAOYSA-N 1,2-phenylenediamine Chemical compound NC1=CC=CC=C1N GEYOCULIXLDCMW-UHFFFAOYSA-N 0.000 description 1
- GOJUJUVQIVIZAV-UHFFFAOYSA-N 2-amino-4,6-dichloropyrimidine-5-carbaldehyde Chemical group NC1=NC(Cl)=C(C=O)C(Cl)=N1 GOJUJUVQIVIZAV-UHFFFAOYSA-N 0.000 description 1
- 229920001605 Dextranomer Polymers 0.000 description 1
- OTMSDBZUPAUEDD-UHFFFAOYSA-N Ethane Chemical compound CC OTMSDBZUPAUEDD-UHFFFAOYSA-N 0.000 description 1
- JOYRKODLDBILNP-UHFFFAOYSA-N Ethyl urethane Chemical compound CCOC(N)=O JOYRKODLDBILNP-UHFFFAOYSA-N 0.000 description 1
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 description 1
- 239000004743 Polypropylene Substances 0.000 description 1
- 241001122767 Theaceae Species 0.000 description 1
- 238000013019 agitation Methods 0.000 description 1
- 125000003118 aryl group Chemical group 0.000 description 1
- 238000007664 blowing Methods 0.000 description 1
- 230000036760 body temperature Effects 0.000 description 1
- 244000309466 calf Species 0.000 description 1
- 150000001768 cations Chemical class 0.000 description 1
- 239000003153 chemical reaction reagent Substances 0.000 description 1
- NWXQKVQOEXCDBQ-UHFFFAOYSA-N chloroethane;1,1-dichloroethane Chemical compound CCCl.CC(Cl)Cl NWXQKVQOEXCDBQ-UHFFFAOYSA-N 0.000 description 1
- 235000012000 cholesterol Nutrition 0.000 description 1
- 239000002131 composite material Substances 0.000 description 1
- 238000006482 condensation reaction Methods 0.000 description 1
- 229920001577 copolymer Polymers 0.000 description 1
- 238000007334 copolymerization reaction Methods 0.000 description 1
- 125000000118 dimethyl group Chemical group [H]C([H])([H])* 0.000 description 1
- 238000006073 displacement reaction Methods 0.000 description 1
- 238000009826 distribution Methods 0.000 description 1
- GKIPXFAANLTWBM-UHFFFAOYSA-N epibromohydrin Chemical compound BrCC1CO1 GKIPXFAANLTWBM-UHFFFAOYSA-N 0.000 description 1
- 238000001914 filtration Methods 0.000 description 1
- PEDCQBHIVMGVHV-UHFFFAOYSA-N glycerol Substances OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 1
- JEGUKCSWCFPDGT-UHFFFAOYSA-N h2o hydrate Chemical compound O.O JEGUKCSWCFPDGT-UHFFFAOYSA-N 0.000 description 1
- 150000003944 halohydrins Chemical class 0.000 description 1
- 235000010299 hexamethylene tetramine Nutrition 0.000 description 1
- 208000027866 inflammatory disease Diseases 0.000 description 1
- 238000002329 infrared spectrum Methods 0.000 description 1
- 238000005342 ion exchange Methods 0.000 description 1
- 150000002500 ions Chemical class 0.000 description 1
- 150000002632 lipids Chemical class 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- VNWKTOKETHGBQD-UHFFFAOYSA-N methane Natural products C VNWKTOKETHGBQD-UHFFFAOYSA-N 0.000 description 1
- 238000002156 mixing Methods 0.000 description 1
- 229910052757 nitrogen Inorganic materials 0.000 description 1
- 231100000926 not very toxic Toxicity 0.000 description 1
- 238000000655 nuclear magnetic resonance spectrum Methods 0.000 description 1
- 238000011017 operating method Methods 0.000 description 1
- 150000002924 oxiranes Chemical class 0.000 description 1
- 239000008188 pellet Substances 0.000 description 1
- 230000000144 pharmacologic effect Effects 0.000 description 1
- 239000011148 porous material Substances 0.000 description 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 description 1
- 230000009919 sequestration Effects 0.000 description 1
- 210000002784 stomach Anatomy 0.000 description 1
- 150000003462 sulfoxides Chemical class 0.000 description 1
- YBRBMKDOPFTVDT-UHFFFAOYSA-N tert-butylamine Chemical compound CC(C)(C)N YBRBMKDOPFTVDT-UHFFFAOYSA-N 0.000 description 1
- YXFVVABEGXRONW-UHFFFAOYSA-N toluene Substances CC1=CC=CC=C1 YXFVVABEGXRONW-UHFFFAOYSA-N 0.000 description 1
- 238000005303 weighing Methods 0.000 description 1
- 230000037303 wrinkles Effects 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G18/00—Polymeric products of isocyanates or isothiocyanates
- C08G18/06—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen
- C08G18/83—Chemically modified polymers
- C08G18/833—Chemically modified polymers by nitrogen containing compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/74—Synthetic polymeric materials
- A61K31/785—Polymers containing nitrogen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/84—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
- A61K8/87—Polyurethanes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/22—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing macromolecular materials
- A61L15/26—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/42—Use of materials characterised by their function or physical properties
- A61L15/60—Liquid-swellable gel-forming materials, e.g. super-absorbents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G18/00—Polymeric products of isocyanates or isothiocyanates
- C08G18/06—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen
- C08G18/08—Processes
- C08G18/0804—Manufacture of polymers containing ionic or ionogenic groups
- C08G18/0809—Manufacture of polymers containing ionic or ionogenic groups containing cationic or cationogenic groups
- C08G18/0814—Manufacture of polymers containing ionic or ionogenic groups containing cationic or cationogenic groups containing ammonium groups or groups forming them
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Hematology (AREA)
- Polymers & Plastics (AREA)
- Materials Engineering (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Dispersion Chemistry (AREA)
- Manufacturing & Machinery (AREA)
- Dermatology (AREA)
- Birds (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Polyurethanes Or Polyureas (AREA)
- Cosmetics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Epoxy Resins (AREA)
Priority Applications (12)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR8014515A FR2485548A1 (fr) | 1980-06-30 | 1980-06-30 | Procede de preparation d'un polymere de structure tridimensionnelle du type polyurethane reticule, produit obtenu selon ce procede et son application en tant qu'agent gonflant, notamment en therapeutique |
| DE8181401009T DE3166452D1 (en) | 1980-06-30 | 1981-06-23 | Process for the preparation of a polymer of the cross-linked polyurethane type having a tridimensional structure, product obtained by this process and its use as a swelling agent, especially therapeutically |
| AT81401009T ATE9706T1 (de) | 1980-06-30 | 1981-06-23 | Verfahren zur herstellung eines polymers mit dreidimensionaler struktur des typs querverbundenes polyurethan, bei diesem verfahren erhaltenes produkt sowie seine verwendung als quellmittel, insbesondere in der therapie. |
| EP81401009A EP0043317B1 (fr) | 1980-06-30 | 1981-06-23 | Procédé de préparation d'un polymère de structure tridimensionnelle du type polyuréthane réticulé, produit obtenu selon ce procédé et son application en tant qu'agent gonflant, notamment en thérapeutique |
| CS814946A CS234027B2 (en) | 1980-06-30 | 1981-06-29 | Method of polymer preparation with three-dimensional structure type netted polyurethane |
| US06/278,845 US4340699A (en) | 1980-06-30 | 1981-06-29 | Process for preparing a polymer of three-dimensional structure of the cross-linked polyurethane type, product obtained according to this process and application thereof as swelling agent, particularly in therapeutics |
| BR8104108A BR8104108A (pt) | 1980-06-30 | 1981-06-29 | Processo de preparacao de um polimero de estrutura tridimencional do tipo poliuretano reticulado,produto esse obtido de acordo com esse obtido de acordo com esse processo,e sua aplicacao como agente inflavel |
| ES503506A ES503506A0 (es) | 1980-06-30 | 1981-06-29 | Procedimiento de preparacion de un polimero de estructura tridimensional del tipo de poliuretano reticulado. |
| AR285895A AR230838A1 (es) | 1980-06-30 | 1981-06-29 | Un procedimiento de preparacion de un polimero de estructura tridimensional del tipo del poliuretano reticulado y que tiene un buen poder de hinchamiento,polimero obtenido con el mismo,y una composicion util que lo contiene |
| CA000380795A CA1198247A (en) | 1980-06-30 | 1981-06-29 | Process for preparing a polymer of three-dimensional structure of the cross-linked polyurethane type, product obtained according to this process and application thereof as swelling agent |
| DD81231314A DD159642A5 (de) | 1980-06-30 | 1981-06-30 | Verfahren zur herstellung eines polymers mit dreidimensionaler struktur eines polyurethanradikals |
| JP56103890A JPS57126814A (en) | 1980-06-30 | 1981-06-30 | Three-dimensionally bridged polyurethane type polymer and manufacture |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR8014515A FR2485548A1 (fr) | 1980-06-30 | 1980-06-30 | Procede de preparation d'un polymere de structure tridimensionnelle du type polyurethane reticule, produit obtenu selon ce procede et son application en tant qu'agent gonflant, notamment en therapeutique |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FR2485548A1 true FR2485548A1 (fr) | 1981-12-31 |
| FR2485548B1 FR2485548B1 (enExample) | 1982-11-12 |
Family
ID=9243672
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR8014515A Granted FR2485548A1 (fr) | 1980-06-30 | 1980-06-30 | Procede de preparation d'un polymere de structure tridimensionnelle du type polyurethane reticule, produit obtenu selon ce procede et son application en tant qu'agent gonflant, notamment en therapeutique |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US4340699A (enExample) |
| EP (1) | EP0043317B1 (enExample) |
| JP (1) | JPS57126814A (enExample) |
| AR (1) | AR230838A1 (enExample) |
| AT (1) | ATE9706T1 (enExample) |
| BR (1) | BR8104108A (enExample) |
| CA (1) | CA1198247A (enExample) |
| CS (1) | CS234027B2 (enExample) |
| DD (1) | DD159642A5 (enExample) |
| DE (1) | DE3166452D1 (enExample) |
| ES (1) | ES503506A0 (enExample) |
| FR (1) | FR2485548A1 (enExample) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS59124922A (ja) * | 1982-12-31 | 1984-07-19 | Nippon Paint Co Ltd | 顔料分散用樹脂 |
| DE4025912A1 (de) * | 1990-08-16 | 1992-02-20 | Werner Ratjen | Mittel zur oralen einnahme |
| US20030072804A1 (en) * | 2001-03-19 | 2003-04-17 | The Procter & Gamble Company | Use of non-digestible polymeric foams to sequester ingested materials thereby inhibiting their absorption by the body |
| US20030091610A1 (en) * | 2001-03-19 | 2003-05-15 | The Procter & Gamble Company | Use of non-digestible polymeric foams to sequester ingested materials thereby inhibiting their absorption by the body |
| US6723495B2 (en) | 2002-01-24 | 2004-04-20 | Kodak Polychrome Graphics Llc | Water-developable negative-working ultraviolet and infrared imageable element |
| US6743254B2 (en) * | 2002-02-01 | 2004-06-01 | Mentor Corporation | Tissue expander with protection against accidental puncture |
| US8372430B2 (en) * | 2002-12-17 | 2013-02-12 | The Procter & Gamble Company | Compositions, methods, and kits useful for the alleviation of gastrointestinal effects |
| US7794512B2 (en) * | 2007-03-16 | 2010-09-14 | Afton Chemical Corporation | Supplying tungsten to a combustion system or combustion system exhaust stream containing iron |
| CN104622851B (zh) * | 2015-03-13 | 2017-09-12 | 山东省药学科学院 | 一种减肥胶囊及其制备方法 |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4127516A (en) * | 1977-02-28 | 1978-11-28 | W. R. Grace & Co. | Hydrophilic polyurethane foams with good wet strength |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5015027B1 (enExample) * | 1971-03-16 | 1975-06-02 | ||
| US4000214A (en) * | 1973-05-29 | 1976-12-28 | Reichhold Chemicals, Inc. | Urethane additive to a standard epoxy resin to improve adhesion to vinyl materials |
| US4143009A (en) * | 1977-03-02 | 1979-03-06 | Frank Dewey | Polyurethane-epoxy casting resin |
-
1980
- 1980-06-30 FR FR8014515A patent/FR2485548A1/fr active Granted
-
1981
- 1981-06-23 DE DE8181401009T patent/DE3166452D1/de not_active Expired
- 1981-06-23 EP EP81401009A patent/EP0043317B1/fr not_active Expired
- 1981-06-23 AT AT81401009T patent/ATE9706T1/de not_active IP Right Cessation
- 1981-06-29 BR BR8104108A patent/BR8104108A/pt unknown
- 1981-06-29 ES ES503506A patent/ES503506A0/es active Granted
- 1981-06-29 AR AR285895A patent/AR230838A1/es active
- 1981-06-29 CA CA000380795A patent/CA1198247A/en not_active Expired
- 1981-06-29 US US06/278,845 patent/US4340699A/en not_active Expired - Fee Related
- 1981-06-29 CS CS814946A patent/CS234027B2/cs unknown
- 1981-06-30 JP JP56103890A patent/JPS57126814A/ja active Pending
- 1981-06-30 DD DD81231314A patent/DD159642A5/de unknown
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4127516A (en) * | 1977-02-28 | 1978-11-28 | W. R. Grace & Co. | Hydrophilic polyurethane foams with good wet strength |
Also Published As
| Publication number | Publication date |
|---|---|
| CS234027B2 (en) | 1985-03-14 |
| DD159642A5 (de) | 1983-03-23 |
| ES8301252A1 (es) | 1982-12-01 |
| EP0043317A1 (fr) | 1982-01-06 |
| ATE9706T1 (de) | 1984-10-15 |
| BR8104108A (pt) | 1982-03-16 |
| DE3166452D1 (en) | 1984-11-08 |
| US4340699A (en) | 1982-07-20 |
| JPS57126814A (en) | 1982-08-06 |
| ES503506A0 (es) | 1982-12-01 |
| AR230838A1 (es) | 1984-07-31 |
| CA1198247A (en) | 1985-12-17 |
| EP0043317B1 (fr) | 1984-10-03 |
| FR2485548B1 (enExample) | 1982-11-12 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| SU905228A1 (ru) | Способ получени полимочевины | |
| CN1235916C (zh) | 包含交联聚轮烷的化合物 | |
| EP0117768B1 (fr) | Hydrogels de polyuréthane et leur procédé de fabrication | |
| EP0179023B1 (fr) | Polypeptide biodégradable et son utilisation pour le relargage progressif de médicaments | |
| CN106947051B (zh) | 一种聚氨酯接枝的纤维素纳米晶及其制备方法 | |
| FR2485548A1 (fr) | Procede de preparation d'un polymere de structure tridimensionnelle du type polyurethane reticule, produit obtenu selon ce procede et son application en tant qu'agent gonflant, notamment en therapeutique | |
| EP1521795B1 (fr) | Polymeres thermosensibles et gels thermoreversibles obtenus a partir de ces polymeres | |
| FR2497514A1 (fr) | Procede de preparation d'hydrogels a forte capacite d'absorption d'eau, mais peu solubles dans l'eau, et produits ainsi obtenus | |
| CN101287775A (zh) | 包含聚轮烷和聚合物的材料、及其制造方法 | |
| FR2728575A1 (fr) | Sels de chitosane ayant des proprietes d'absorption ameliorees, et leur procede de preparation | |
| FR2494285A1 (fr) | Compositions de polyurethane diacrylates hydrophiles, leurs utilisations et procede de preparation | |
| JPWO2001083566A1 (ja) | 架橋ポリロタキサンを有する化合物 | |
| EP2702079A1 (en) | Amphoteric materials based on crosslinked hyaluronic acid, method of preparation thereof, materials containing entrapped active agents, method of preparation thereof, and use of said materials | |
| JPWO2006090819A1 (ja) | ポリロタキサン及びポリマー並びにイオン性液体を有する材料、及びその製造方法 | |
| FR2691971A1 (fr) | Matériau hydrogel, pansement à base d'un tel matériau et procédé de fabrication dudit pansement. | |
| JP5430091B2 (ja) | 高吸水性樹脂およびその製造方法 | |
| Huynh et al. | Preparation and swelling properties of “click” hydrogel from polyaspartamide derivatives using tri-arm PEG and PEG-co-poly (amino urethane) azides as crosslinking agents | |
| CN1031544A (zh) | 水淬硬化聚合物制剂 | |
| Tamer et al. | Lysine-derived, pH-sensitive and biodegradable poly (beta-aminoester urethane) networks and their local drug delivery behaviour | |
| Rahmani et al. | One-pot synthesis of dibenzaldehyde-terminated poly (ethylene glycol) for preparation of dynamic chitosan-based amphiphilic hydrogels | |
| EP0894823B1 (fr) | Articles médicaux non cytotoxiques en polyuréthane | |
| CN1292038C (zh) | 亲水性聚氨酯压敏胶及其制备方法 | |
| EP0258120B1 (fr) | Polymère en poudre, son procédé de préparation et son application à l'absorption de fluides aqueux | |
| CN109569533B (zh) | 一种聚氨酯石墨烯手性柱材料及其制备方法 | |
| JP7100314B2 (ja) | ロタキサンおよびこれを用いたポリウレタン |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| TP | Transmission of property | ||
| ST | Notification of lapse |