FR2482309A1 - Procede de detection de la presence d'antigenes d'un groupe sanguin dans une coupe histologique, et produits pour mettre en oeuvre ce procede - Google Patents
Procede de detection de la presence d'antigenes d'un groupe sanguin dans une coupe histologique, et produits pour mettre en oeuvre ce procede Download PDFInfo
- Publication number
- FR2482309A1 FR2482309A1 FR8008893A FR8008893A FR2482309A1 FR 2482309 A1 FR2482309 A1 FR 2482309A1 FR 8008893 A FR8008893 A FR 8008893A FR 8008893 A FR8008893 A FR 8008893A FR 2482309 A1 FR2482309 A1 FR 2482309A1
- Authority
- FR
- France
- Prior art keywords
- antiserum
- labeled
- histological section
- process according
- serum
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 239000000427 antigen Substances 0.000 title claims abstract description 18
- 102000036639 antigens Human genes 0.000 title claims abstract description 18
- 108091007433 antigens Proteins 0.000 title claims abstract description 18
- 238000000034 method Methods 0.000 title claims description 31
- 210000004369 blood Anatomy 0.000 title claims description 6
- 239000008280 blood Substances 0.000 title claims description 6
- 230000003287 optical effect Effects 0.000 claims abstract description 5
- 210000002966 serum Anatomy 0.000 claims description 16
- 239000003550 marker Substances 0.000 claims description 13
- 238000002372 labelling Methods 0.000 claims description 10
- 239000000126 substance Substances 0.000 claims description 9
- 239000003795 chemical substances by application Substances 0.000 claims description 8
- 102000003992 Peroxidases Human genes 0.000 claims description 7
- GNBHRKFJIUUOQI-UHFFFAOYSA-N fluorescein Chemical compound O1C(=O)C2=CC=CC=C2C21C1=CC=C(O)C=C1OC1=CC(O)=CC=C21 GNBHRKFJIUUOQI-UHFFFAOYSA-N 0.000 claims description 7
- 108040007629 peroxidase activity proteins Proteins 0.000 claims description 7
- PYWVYCXTNDRMGF-UHFFFAOYSA-N rhodamine B Chemical compound [Cl-].C=12C=CC(=[N+](CC)CC)C=C2OC2=CC(N(CC)CC)=CC=C2C=1C1=CC=CC=C1C(O)=O PYWVYCXTNDRMGF-UHFFFAOYSA-N 0.000 claims description 7
- 101710098119 Chaperonin GroEL 2 Proteins 0.000 claims description 2
- 101000588258 Taenia solium Paramyosin Proteins 0.000 claims description 2
- 206010028980 Neoplasm Diseases 0.000 abstract description 2
- 238000011156 evaluation Methods 0.000 abstract description 2
- 230000003211 malignant effect Effects 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 description 6
- 210000004027 cell Anatomy 0.000 description 5
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 3
- 210000001519 tissue Anatomy 0.000 description 3
- 238000005406 washing Methods 0.000 description 3
- CSCPPACGZOOCGX-UHFFFAOYSA-N Acetone Chemical compound CC(C)=O CSCPPACGZOOCGX-UHFFFAOYSA-N 0.000 description 2
- 101710145634 Antigen 1 Proteins 0.000 description 2
- 108060003951 Immunoglobulin Proteins 0.000 description 2
- 239000007853 buffer solution Substances 0.000 description 2
- 201000011510 cancer Diseases 0.000 description 2
- 102000018358 immunoglobulin Human genes 0.000 description 2
- COXVTLYNGOIATD-HVMBLDELSA-N CC1=C(C=CC(=C1)C1=CC(C)=C(C=C1)\N=N\C1=C(O)C2=C(N)C(=CC(=C2C=C1)S(O)(=O)=O)S(O)(=O)=O)\N=N\C1=CC=C2C(=CC(=C(N)C2=C1O)S(O)(=O)=O)S(O)(=O)=O Chemical compound CC1=C(C=CC(=C1)C1=CC(C)=C(C=C1)\N=N\C1=C(O)C2=C(N)C(=CC(=C2C=C1)S(O)(=O)=O)S(O)(=O)=O)\N=N\C1=CC=C2C(=CC(=C(N)C2=C1O)S(O)(=O)=O)S(O)(=O)=O COXVTLYNGOIATD-HVMBLDELSA-N 0.000 description 1
- 206010018910 Haemolysis Diseases 0.000 description 1
- 241000446313 Lamella Species 0.000 description 1
- 208000007097 Urinary Bladder Neoplasms Diseases 0.000 description 1
- 230000004520 agglutination Effects 0.000 description 1
- 210000000988 bone and bone Anatomy 0.000 description 1
- 210000000481 breast Anatomy 0.000 description 1
- 210000003679 cervix uteri Anatomy 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 210000001072 colon Anatomy 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 238000001514 detection method Methods 0.000 description 1
- 238000001035 drying Methods 0.000 description 1
- 230000008030 elimination Effects 0.000 description 1
- 238000003379 elimination reaction Methods 0.000 description 1
- 210000003743 erythrocyte Anatomy 0.000 description 1
- 229960003699 evans blue Drugs 0.000 description 1
- MHMNJMPURVTYEJ-UHFFFAOYSA-N fluorescein-5-isothiocyanate Chemical compound O1C(=O)C2=CC(N=C=S)=CC=C2C21C1=CC=C(O)C=C1OC1=CC(O)=CC=C21 MHMNJMPURVTYEJ-UHFFFAOYSA-N 0.000 description 1
- 230000008014 freezing Effects 0.000 description 1
- 238000007710 freezing Methods 0.000 description 1
- 230000008588 hemolysis Effects 0.000 description 1
- 238000005286 illumination Methods 0.000 description 1
- 150000002540 isothiocyanates Chemical class 0.000 description 1
- 239000002184 metal Substances 0.000 description 1
- 239000008363 phosphate buffer Substances 0.000 description 1
- 238000004393 prognosis Methods 0.000 description 1
- 238000011002 quantification Methods 0.000 description 1
- 229920005989 resin Polymers 0.000 description 1
- 239000011347 resin Substances 0.000 description 1
- 239000000243 solution Substances 0.000 description 1
- 239000000758 substrate Substances 0.000 description 1
- 229920003002 synthetic resin Polymers 0.000 description 1
- 239000000057 synthetic resin Substances 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/80—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood groups or blood types or red blood cells
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Hematology (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Urology & Nephrology (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Cell Biology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Microbiology (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
Priority Applications (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR8008893A FR2482309A1 (fr) | 1980-04-21 | 1980-04-21 | Procede de detection de la presence d'antigenes d'un groupe sanguin dans une coupe histologique, et produits pour mettre en oeuvre ce procede |
| EP81400562A EP0038738A1 (fr) | 1980-04-21 | 1981-04-09 | Procédé de détection de la présence d'antigènes d'un groupe sanguin dans une coupe histologique, et produits pour mettre en oeuvre ce procédé |
| DK169381A DK169381A (da) | 1980-04-21 | 1981-04-14 | Fremgangsmaade til detektion af en blodgruppes antigener og m2ddel til udoevelse af fremgangsmaaden |
| ES501387A ES8206857A1 (es) | 1980-04-21 | 1981-04-15 | Procedimiento de deteccion de la presencia de antigenos de un grupo sanguineo a,b,0 o ab en un corte histologico |
| GR64712A GR74513B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1980-04-21 | 1981-04-16 | |
| JP5864581A JPS56166465A (en) | 1980-04-21 | 1981-04-20 | Method of detecting blood typing antigen in tissue piece and product obtained thereby |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR8008893A FR2482309A1 (fr) | 1980-04-21 | 1980-04-21 | Procede de detection de la presence d'antigenes d'un groupe sanguin dans une coupe histologique, et produits pour mettre en oeuvre ce procede |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| FR2482309A1 true FR2482309A1 (fr) | 1981-11-13 |
Family
ID=9241156
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR8008893A Withdrawn FR2482309A1 (fr) | 1980-04-21 | 1980-04-21 | Procede de detection de la presence d'antigenes d'un groupe sanguin dans une coupe histologique, et produits pour mettre en oeuvre ce procede |
Country Status (6)
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1997022881A1 (fr) * | 1995-12-15 | 1997-06-26 | Valentin Sergeevich Erkhov | Procede de diagnostic de la presence d'une tumeur maligne |
| US7160686B1 (en) | 1998-04-20 | 2007-01-09 | Widnes Company Inc. | Method for producing a specific antiserum against the universal tumorous antigen and method for diagnosing malignant tumours using said antiserum |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2503870A1 (fr) * | 1981-04-10 | 1982-10-15 | Fella Christian | Procede de detection de la presence d'antigenes pneumocoque xiv dans un prelevement de cellules humaines, et produits pour mettre en oeuvre ce procede |
| US4550017A (en) * | 1982-10-15 | 1985-10-29 | Syntex (U.S.A.) Inc. | Fluorescence screening for blood typing |
| JPS60253870A (ja) * | 1984-05-08 | 1985-12-14 | Sekisui Chem Co Ltd | 免疫学的診断方法 |
| US4748129A (en) * | 1984-08-28 | 1988-05-31 | Snytex (U.S.A.) Inc. | Assay method employing fluorescent cell incorporative dye |
| US5145774A (en) * | 1984-08-28 | 1992-09-08 | Syntex (U.S.A.) Inc. | Fluorescent dyes |
| US4912031A (en) * | 1987-10-23 | 1990-03-27 | E. I. Du Pont De Nemours And Company | Method for detecting carcinomatous and precarcinomatous colo-rectal disease |
-
1980
- 1980-04-21 FR FR8008893A patent/FR2482309A1/fr not_active Withdrawn
-
1981
- 1981-04-09 EP EP81400562A patent/EP0038738A1/fr not_active Withdrawn
- 1981-04-14 DK DK169381A patent/DK169381A/da active IP Right Grant
- 1981-04-15 ES ES501387A patent/ES8206857A1/es not_active Expired
- 1981-04-16 GR GR64712A patent/GR74513B/el unknown
- 1981-04-20 JP JP5864581A patent/JPS56166465A/ja active Pending
Non-Patent Citations (4)
| Title |
|---|
| CA1973 * |
| CA1974 * |
| CA1976 * |
| CA1979 * |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1997022881A1 (fr) * | 1995-12-15 | 1997-06-26 | Valentin Sergeevich Erkhov | Procede de diagnostic de la presence d'une tumeur maligne |
| US7160686B1 (en) | 1998-04-20 | 2007-01-09 | Widnes Company Inc. | Method for producing a specific antiserum against the universal tumorous antigen and method for diagnosing malignant tumours using said antiserum |
Also Published As
| Publication number | Publication date |
|---|---|
| ES501387A0 (es) | 1982-08-16 |
| EP0038738A1 (fr) | 1981-10-28 |
| ES8206857A1 (es) | 1982-08-16 |
| JPS56166465A (en) | 1981-12-21 |
| DK169381A (da) | 1981-10-22 |
| GR74513B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1984-06-29 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ST | Notification of lapse | ||
| AR | Application made for restoration | ||
| DI | Inadmissibility of an action of restoration |