FR2460950A1 - Nouvelles 4-phenyl-4,5,6,7-tetrahydropyrrolo(2,3-c)pyridines, procede pour leur preparation et medicaments les renfermant - Google Patents
Nouvelles 4-phenyl-4,5,6,7-tetrahydropyrrolo(2,3-c)pyridines, procede pour leur preparation et medicaments les renfermant Download PDFInfo
- Publication number
- FR2460950A1 FR2460950A1 FR8015010A FR8015010A FR2460950A1 FR 2460950 A1 FR2460950 A1 FR 2460950A1 FR 8015010 A FR8015010 A FR 8015010A FR 8015010 A FR8015010 A FR 8015010A FR 2460950 A1 FR2460950 A1 FR 2460950A1
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- FR
- France
- Prior art keywords
- group
- tetrahydro
- methyl
- dimethyl
- general formula
- Prior art date
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- Granted
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- 235000005985 organic acids Nutrition 0.000 description 1
- 239000012074 organic phase Substances 0.000 description 1
- 239000003960 organic solvent Substances 0.000 description 1
- FJKROLUGYXJWQN-UHFFFAOYSA-N papa-hydroxy-benzoic acid Natural products OC(=O)C1=CC=C(O)C=C1 FJKROLUGYXJWQN-UHFFFAOYSA-N 0.000 description 1
- 230000002093 peripheral effect Effects 0.000 description 1
- 239000003208 petroleum Substances 0.000 description 1
- 239000000825 pharmaceutical preparation Substances 0.000 description 1
- 229940127557 pharmaceutical product Drugs 0.000 description 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 description 1
- 229950006768 phenylethanolamine Drugs 0.000 description 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 description 1
- 235000019260 propionic acid Nutrition 0.000 description 1
- IUVKMZGDUIUOCP-BTNSXGMBSA-N quinbolone Chemical compound O([C@H]1CC[C@H]2[C@H]3[C@@H]([C@]4(C=CC(=O)C=C4CC3)C)CC[C@@]21C)C1=CCCC1 IUVKMZGDUIUOCP-BTNSXGMBSA-N 0.000 description 1
- 230000002285 radioactive effect Effects 0.000 description 1
- 238000011084 recovery Methods 0.000 description 1
- 229960004889 salicylic acid Drugs 0.000 description 1
- 239000000741 silica gel Substances 0.000 description 1
- 229910002027 silica gel Inorganic materials 0.000 description 1
- 239000011780 sodium chloride Substances 0.000 description 1
- HRZFUMHJMZEROT-UHFFFAOYSA-L sodium disulfite Chemical compound [Na+].[Na+].[O-]S(=O)S([O-])(=O)=O HRZFUMHJMZEROT-UHFFFAOYSA-L 0.000 description 1
- 235000010262 sodium metabisulphite Nutrition 0.000 description 1
- 239000011877 solvent mixture Substances 0.000 description 1
- 230000004936 stimulating effect Effects 0.000 description 1
- IIACRCGMVDHOTQ-UHFFFAOYSA-N sulfamic acid Chemical class NS(O)(=O)=O IIACRCGMVDHOTQ-UHFFFAOYSA-N 0.000 description 1
- 229910021653 sulphate ion Inorganic materials 0.000 description 1
- 230000001629 suppression Effects 0.000 description 1
- 239000000454 talc Substances 0.000 description 1
- 229910052623 talc Inorganic materials 0.000 description 1
- 235000002906 tartaric acid Nutrition 0.000 description 1
- 239000011975 tartaric acid Substances 0.000 description 1
- RWRDLPDLKQPQOW-UHFFFAOYSA-N tetrahydropyrrole Substances C1CCNC1 RWRDLPDLKQPQOW-UHFFFAOYSA-N 0.000 description 1
- 230000001519 thymoleptic effect Effects 0.000 description 1
- 239000004408 titanium dioxide Substances 0.000 description 1
- 239000008096 xylene Substances 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/32—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D207/33—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D207/335—Radicals substituted by nitrogen atoms not forming part of a nitro radical
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19792927294 DE2927294A1 (de) | 1979-07-06 | 1979-07-06 | Neue 4-phenyl-4,5,6,7-tetrahydropyrrolo eckige klammer auf 2,3-c eckige klammer zu pyridine, verfahren zu ihrer herstellung und pharmazeutische zusammensetzungen |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FR2460950A1 true FR2460950A1 (fr) | 1981-01-30 |
| FR2460950B1 FR2460950B1 (OSRAM) | 1983-06-24 |
Family
ID=6075042
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR8015010A Granted FR2460950A1 (fr) | 1979-07-06 | 1980-07-04 | Nouvelles 4-phenyl-4,5,6,7-tetrahydropyrrolo(2,3-c)pyridines, procede pour leur preparation et medicaments les renfermant |
Country Status (26)
| Country | Link |
|---|---|
| US (1) | US4315938A (OSRAM) |
| JP (1) | JPS5610184A (OSRAM) |
| AT (1) | AT375077B (OSRAM) |
| AU (1) | AU536336B2 (OSRAM) |
| BE (1) | BE884193A (OSRAM) |
| CA (1) | CA1138864A (OSRAM) |
| CH (1) | CH649548A5 (OSRAM) |
| DE (1) | DE2927294A1 (OSRAM) |
| DK (1) | DK290380A (OSRAM) |
| ES (1) | ES8201019A1 (OSRAM) |
| FI (1) | FI802148A7 (OSRAM) |
| FR (1) | FR2460950A1 (OSRAM) |
| GB (1) | GB2054580B (OSRAM) |
| GR (1) | GR69327B (OSRAM) |
| HU (1) | HU182152B (OSRAM) |
| IL (1) | IL60499A (OSRAM) |
| IT (1) | IT1150024B (OSRAM) |
| LU (1) | LU82582A1 (OSRAM) |
| NL (1) | NL8003879A (OSRAM) |
| NO (1) | NO802014L (OSRAM) |
| NZ (1) | NZ194245A (OSRAM) |
| PH (1) | PH15756A (OSRAM) |
| PT (1) | PT71500B (OSRAM) |
| SE (1) | SE436747B (OSRAM) |
| YU (1) | YU174780A (OSRAM) |
| ZA (1) | ZA804031B (OSRAM) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5890951A (ja) * | 1981-11-26 | 1983-05-30 | 住友金属工業株式会社 | 耐食性にすぐれた積層板 |
| JPS59193175A (ja) * | 1983-04-19 | 1984-11-01 | Toa Nenryo Kogyo Kk | 積層物 |
| US4572911A (en) * | 1984-08-02 | 1986-02-25 | Mcneilab, Inc. | Hexahydroindolinzine compounds, pharmaceutical compositions and methods and intermediates |
| WO2021021953A2 (en) * | 2019-07-30 | 2021-02-04 | Sanford Burnham Prebys Medical Discovery Institute | Dopamine receptor d1 agonists and methods of use |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2405948A1 (fr) * | 1977-10-15 | 1979-05-11 | Boehringer Sohn Ingelheim | Nouvelles 4-phenyl-thieno-(2,3-c)- piperidines, procedes pour leur preparation et compositions pharmaceutiques les renfermant |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1484140A (en) * | 1974-04-24 | 1977-08-24 | Wyeth John & Brother Ltd | Pyrrolopyridine derivatives |
-
1979
- 1979-07-06 DE DE19792927294 patent/DE2927294A1/de not_active Withdrawn
-
1980
- 1980-06-30 US US06/163,969 patent/US4315938A/en not_active Expired - Lifetime
- 1980-06-30 IT IT23120/80A patent/IT1150024B/it active
- 1980-07-02 AT AT0344680A patent/AT375077B/de not_active IP Right Cessation
- 1980-07-03 YU YU01747/80A patent/YU174780A/xx unknown
- 1980-07-03 GR GR62353A patent/GR69327B/el unknown
- 1980-07-03 CH CH5125/80A patent/CH649548A5/de not_active IP Right Cessation
- 1980-07-04 LU LU82582A patent/LU82582A1/de unknown
- 1980-07-04 FI FI802148A patent/FI802148A7/fi not_active Application Discontinuation
- 1980-07-04 ES ES493104A patent/ES8201019A1/es not_active Expired
- 1980-07-04 NZ NZ194245A patent/NZ194245A/en unknown
- 1980-07-04 BE BE0/201313A patent/BE884193A/fr not_active IP Right Cessation
- 1980-07-04 HU HU801678A patent/HU182152B/hu unknown
- 1980-07-04 FR FR8015010A patent/FR2460950A1/fr active Granted
- 1980-07-04 GB GB8022046A patent/GB2054580B/en not_active Expired
- 1980-07-04 JP JP9161580A patent/JPS5610184A/ja active Pending
- 1980-07-04 NO NO802014A patent/NO802014L/no unknown
- 1980-07-04 IL IL60499A patent/IL60499A/xx unknown
- 1980-07-04 NL NL8003879A patent/NL8003879A/nl not_active Application Discontinuation
- 1980-07-04 AU AU60138/80A patent/AU536336B2/en not_active Ceased
- 1980-07-04 DK DK290380A patent/DK290380A/da not_active Application Discontinuation
- 1980-07-04 SE SE8004976A patent/SE436747B/sv unknown
- 1980-07-04 PT PT71500A patent/PT71500B/pt unknown
- 1980-07-04 CA CA000355540A patent/CA1138864A/en not_active Expired
- 1980-07-04 ZA ZA00804031A patent/ZA804031B/xx unknown
- 1980-07-07 PH PH24246A patent/PH15756A/en unknown
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2405948A1 (fr) * | 1977-10-15 | 1979-05-11 | Boehringer Sohn Ingelheim | Nouvelles 4-phenyl-thieno-(2,3-c)- piperidines, procedes pour leur preparation et compositions pharmaceutiques les renfermant |
Also Published As
| Publication number | Publication date |
|---|---|
| CH649548A5 (de) | 1985-05-31 |
| FR2460950B1 (OSRAM) | 1983-06-24 |
| CA1138864A (en) | 1983-01-04 |
| HU182152B (en) | 1983-12-28 |
| ES493104A0 (es) | 1981-11-01 |
| ZA804031B (en) | 1982-03-31 |
| GB2054580B (en) | 1983-04-07 |
| ATA344680A (de) | 1983-11-15 |
| LU82582A1 (de) | 1981-09-10 |
| IL60499A0 (en) | 1980-09-16 |
| IT1150024B (it) | 1986-12-10 |
| IL60499A (en) | 1984-02-29 |
| GB2054580A (en) | 1981-02-18 |
| AU6013880A (en) | 1981-01-15 |
| PT71500A (de) | 1980-08-01 |
| DE2927294A1 (de) | 1981-01-08 |
| US4315938A (en) | 1982-02-16 |
| PH15756A (en) | 1983-03-18 |
| JPS5610184A (en) | 1981-02-02 |
| SE8004976L (sv) | 1981-01-07 |
| NL8003879A (nl) | 1981-01-08 |
| DK290380A (da) | 1981-01-07 |
| ES8201019A1 (es) | 1981-11-01 |
| AT375077B (de) | 1984-06-25 |
| NZ194245A (en) | 1984-07-06 |
| FI802148A7 (fi) | 1981-01-01 |
| GR69327B (OSRAM) | 1982-05-17 |
| PT71500B (de) | 1981-12-11 |
| IT8023120A0 (it) | 1980-06-30 |
| BE884193A (fr) | 1981-01-05 |
| NO802014L (no) | 1981-01-07 |
| SE436747B (sv) | 1985-01-21 |
| YU174780A (en) | 1983-02-28 |
| AU536336B2 (en) | 1984-05-03 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ST | Notification of lapse |