NL8003879A - Nieuwe 4-fenyl-4.5.6.7-tetrahydro-pyrrolo/2,3-c/pyri- dinen, werkwijze ter bereiding daarvan, en farmaceutische preparatn, die deze verbindingen bevatten. - Google Patents
Nieuwe 4-fenyl-4.5.6.7-tetrahydro-pyrrolo/2,3-c/pyri- dinen, werkwijze ter bereiding daarvan, en farmaceutische preparatn, die deze verbindingen bevatten. Download PDFInfo
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- NL8003879A NL8003879A NL8003879A NL8003879A NL8003879A NL 8003879 A NL8003879 A NL 8003879A NL 8003879 A NL8003879 A NL 8003879A NL 8003879 A NL8003879 A NL 8003879A NL 8003879 A NL8003879 A NL 8003879A
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- Prior art keywords
- general formula
- pyrrolo
- tetrahydro
- compounds
- acid
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- 229940098779 methanesulfonic acid Drugs 0.000 description 1
- 125000000956 methoxy group Chemical group [H]C([H])([H])O* 0.000 description 1
- 150000007522 mineralic acids Chemical class 0.000 description 1
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 description 1
- 229910052757 nitrogen Inorganic materials 0.000 description 1
- 125000004433 nitrogen atom Chemical group N* 0.000 description 1
- QJGQUHMNIGDVPM-UHFFFAOYSA-N nitrogen group Chemical group [N] QJGQUHMNIGDVPM-UHFFFAOYSA-N 0.000 description 1
- 150000002871 norepinephrines Chemical class 0.000 description 1
- 235000005985 organic acids Nutrition 0.000 description 1
- 239000012074 organic phase Substances 0.000 description 1
- 239000003960 organic solvent Substances 0.000 description 1
- 229910052760 oxygen Inorganic materials 0.000 description 1
- 125000004430 oxygen atom Chemical group O* 0.000 description 1
- FJKROLUGYXJWQN-UHFFFAOYSA-N papa-hydroxy-benzoic acid Natural products OC(=O)C1=CC=C(O)C=C1 FJKROLUGYXJWQN-UHFFFAOYSA-N 0.000 description 1
- 239000003208 petroleum Substances 0.000 description 1
- 239000008177 pharmaceutical agent Substances 0.000 description 1
- 229950006768 phenylethanolamine Drugs 0.000 description 1
- 230000000644 propagated effect Effects 0.000 description 1
- 235000019260 propionic acid Nutrition 0.000 description 1
- IUVKMZGDUIUOCP-BTNSXGMBSA-N quinbolone Chemical compound O([C@H]1CC[C@H]2[C@H]3[C@@H]([C@]4(C=CC(=O)C=C4CC3)C)CC[C@@]21C)C1=CCCC1 IUVKMZGDUIUOCP-BTNSXGMBSA-N 0.000 description 1
- 150000003254 radicals Chemical class 0.000 description 1
- 230000002285 radioactive effect Effects 0.000 description 1
- 229960004889 salicylic acid Drugs 0.000 description 1
- 239000000741 silica gel Substances 0.000 description 1
- 229910002027 silica gel Inorganic materials 0.000 description 1
- 239000011780 sodium chloride Substances 0.000 description 1
- HRZFUMHJMZEROT-UHFFFAOYSA-L sodium disulfite Chemical compound [Na+].[Na+].[O-]S(=O)S([O-])(=O)=O HRZFUMHJMZEROT-UHFFFAOYSA-L 0.000 description 1
- 235000010262 sodium metabisulphite Nutrition 0.000 description 1
- 239000011877 solvent mixture Substances 0.000 description 1
- IIACRCGMVDHOTQ-UHFFFAOYSA-N sulfamic acid Chemical compound NS(O)(=O)=O IIACRCGMVDHOTQ-UHFFFAOYSA-N 0.000 description 1
- YBBRCQOCSYXUOC-UHFFFAOYSA-N sulfuryl dichloride Chemical compound ClS(Cl)(=O)=O YBBRCQOCSYXUOC-UHFFFAOYSA-N 0.000 description 1
- 239000000454 talc Substances 0.000 description 1
- 229910052623 talc Inorganic materials 0.000 description 1
- 235000002906 tartaric acid Nutrition 0.000 description 1
- 239000011975 tartaric acid Substances 0.000 description 1
- CMJCEVKJYRZMIA-UHFFFAOYSA-M thallium(i) iodide Chemical compound [Tl]I CMJCEVKJYRZMIA-UHFFFAOYSA-M 0.000 description 1
- 230000001519 thymoleptic effect Effects 0.000 description 1
- 239000004408 titanium dioxide Substances 0.000 description 1
- 238000005303 weighing Methods 0.000 description 1
- 239000008096 xylene Substances 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/32—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D207/33—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D207/335—Radicals substituted by nitrogen atoms not forming part of a nitro radical
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19792927294 DE2927294A1 (de) | 1979-07-06 | 1979-07-06 | Neue 4-phenyl-4,5,6,7-tetrahydropyrrolo eckige klammer auf 2,3-c eckige klammer zu pyridine, verfahren zu ihrer herstellung und pharmazeutische zusammensetzungen |
| DE2927294 | 1979-07-06 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NL8003879A true NL8003879A (nl) | 1981-01-08 |
Family
ID=6075042
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NL8003879A NL8003879A (nl) | 1979-07-06 | 1980-07-04 | Nieuwe 4-fenyl-4.5.6.7-tetrahydro-pyrrolo/2,3-c/pyri- dinen, werkwijze ter bereiding daarvan, en farmaceutische preparatn, die deze verbindingen bevatten. |
Country Status (26)
| Country | Link |
|---|---|
| US (1) | US4315938A (OSRAM) |
| JP (1) | JPS5610184A (OSRAM) |
| AT (1) | AT375077B (OSRAM) |
| AU (1) | AU536336B2 (OSRAM) |
| BE (1) | BE884193A (OSRAM) |
| CA (1) | CA1138864A (OSRAM) |
| CH (1) | CH649548A5 (OSRAM) |
| DE (1) | DE2927294A1 (OSRAM) |
| DK (1) | DK290380A (OSRAM) |
| ES (1) | ES493104A0 (OSRAM) |
| FI (1) | FI802148A7 (OSRAM) |
| FR (1) | FR2460950A1 (OSRAM) |
| GB (1) | GB2054580B (OSRAM) |
| GR (1) | GR69327B (OSRAM) |
| HU (1) | HU182152B (OSRAM) |
| IL (1) | IL60499A (OSRAM) |
| IT (1) | IT1150024B (OSRAM) |
| LU (1) | LU82582A1 (OSRAM) |
| NL (1) | NL8003879A (OSRAM) |
| NO (1) | NO802014L (OSRAM) |
| NZ (1) | NZ194245A (OSRAM) |
| PH (1) | PH15756A (OSRAM) |
| PT (1) | PT71500B (OSRAM) |
| SE (1) | SE436747B (OSRAM) |
| YU (1) | YU174780A (OSRAM) |
| ZA (1) | ZA804031B (OSRAM) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5890951A (ja) * | 1981-11-26 | 1983-05-30 | 住友金属工業株式会社 | 耐食性にすぐれた積層板 |
| JPS59193175A (ja) * | 1983-04-19 | 1984-11-01 | Toa Nenryo Kogyo Kk | 積層物 |
| US4572911A (en) * | 1984-08-02 | 1986-02-25 | Mcneilab, Inc. | Hexahydroindolinzine compounds, pharmaceutical compositions and methods and intermediates |
| EP4003339A4 (en) * | 2019-07-30 | 2023-02-22 | Sanford Burnham Prebys Medical Discovery Institute | DOPAMINE RECEPTOR D1 AGONISTS AND METHODS OF USE |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1484140A (en) * | 1974-04-24 | 1977-08-24 | Wyeth John & Brother Ltd | Pyrrolopyridine derivatives |
| AT368504B (de) * | 1977-10-15 | 1982-10-25 | Boehringer Sohn Ingelheim | Verfahren zur herstellung neuer 4-phenyl-thieno- (2,3-c)-piperidine |
-
1979
- 1979-07-06 DE DE19792927294 patent/DE2927294A1/de not_active Withdrawn
-
1980
- 1980-06-30 IT IT23120/80A patent/IT1150024B/it active
- 1980-06-30 US US06/163,969 patent/US4315938A/en not_active Expired - Lifetime
- 1980-07-02 AT AT0344680A patent/AT375077B/de not_active IP Right Cessation
- 1980-07-03 GR GR62353A patent/GR69327B/el unknown
- 1980-07-03 CH CH5125/80A patent/CH649548A5/de not_active IP Right Cessation
- 1980-07-03 YU YU01747/80A patent/YU174780A/xx unknown
- 1980-07-04 BE BE0/201313A patent/BE884193A/fr not_active IP Right Cessation
- 1980-07-04 CA CA000355540A patent/CA1138864A/en not_active Expired
- 1980-07-04 NL NL8003879A patent/NL8003879A/nl not_active Application Discontinuation
- 1980-07-04 LU LU82582A patent/LU82582A1/de unknown
- 1980-07-04 SE SE8004976A patent/SE436747B/sv unknown
- 1980-07-04 ES ES493104A patent/ES493104A0/es active Granted
- 1980-07-04 AU AU60138/80A patent/AU536336B2/en not_active Ceased
- 1980-07-04 HU HU801678A patent/HU182152B/hu unknown
- 1980-07-04 JP JP9161580A patent/JPS5610184A/ja active Pending
- 1980-07-04 FR FR8015010A patent/FR2460950A1/fr active Granted
- 1980-07-04 NO NO802014A patent/NO802014L/no unknown
- 1980-07-04 DK DK290380A patent/DK290380A/da not_active Application Discontinuation
- 1980-07-04 FI FI802148A patent/FI802148A7/fi not_active Application Discontinuation
- 1980-07-04 ZA ZA00804031A patent/ZA804031B/xx unknown
- 1980-07-04 GB GB8022046A patent/GB2054580B/en not_active Expired
- 1980-07-04 NZ NZ194245A patent/NZ194245A/en unknown
- 1980-07-04 PT PT71500A patent/PT71500B/pt unknown
- 1980-07-04 IL IL60499A patent/IL60499A/xx unknown
- 1980-07-07 PH PH24246A patent/PH15756A/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DK290380A (da) | 1981-01-07 |
| DE2927294A1 (de) | 1981-01-08 |
| JPS5610184A (en) | 1981-02-02 |
| AT375077B (de) | 1984-06-25 |
| AU536336B2 (en) | 1984-05-03 |
| SE8004976L (sv) | 1981-01-07 |
| GB2054580A (en) | 1981-02-18 |
| FR2460950A1 (fr) | 1981-01-30 |
| YU174780A (en) | 1983-02-28 |
| NO802014L (no) | 1981-01-07 |
| BE884193A (fr) | 1981-01-05 |
| NZ194245A (en) | 1984-07-06 |
| PT71500B (de) | 1981-12-11 |
| ES8201019A1 (es) | 1981-11-01 |
| LU82582A1 (de) | 1981-09-10 |
| FR2460950B1 (OSRAM) | 1983-06-24 |
| GB2054580B (en) | 1983-04-07 |
| IT1150024B (it) | 1986-12-10 |
| ES493104A0 (es) | 1981-11-01 |
| IT8023120A0 (it) | 1980-06-30 |
| FI802148A7 (fi) | 1981-01-01 |
| IL60499A0 (en) | 1980-09-16 |
| IL60499A (en) | 1984-02-29 |
| PT71500A (de) | 1980-08-01 |
| HU182152B (en) | 1983-12-28 |
| SE436747B (sv) | 1985-01-21 |
| AU6013880A (en) | 1981-01-15 |
| GR69327B (OSRAM) | 1982-05-17 |
| CH649548A5 (de) | 1985-05-31 |
| ATA344680A (de) | 1983-11-15 |
| US4315938A (en) | 1982-02-16 |
| CA1138864A (en) | 1983-01-04 |
| PH15756A (en) | 1983-03-18 |
| ZA804031B (en) | 1982-03-31 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| A85 | Still pending on 85-01-01 | ||
| BV | The patent application has lapsed |