FR2452478A1 - Amides d'acide farnesylacetique et leur utilisation en tant qu'agents anti-ulcereux et agents antibacteriens - Google Patents

Amides d'acide farnesylacetique et leur utilisation en tant qu'agents anti-ulcereux et agents antibacteriens

Info

Publication number
FR2452478A1
FR2452478A1 FR8005931A FR8005931A FR2452478A1 FR 2452478 A1 FR2452478 A1 FR 2452478A1 FR 8005931 A FR8005931 A FR 8005931A FR 8005931 A FR8005931 A FR 8005931A FR 2452478 A1 FR2452478 A1 FR 2452478A1
Authority
FR
France
Prior art keywords
agents
acid amides
antibacterial agents
farnesylacetic acid
radical
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR8005931A
Other languages
English (en)
Other versions
FR2452478B1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kuraray Co Ltd
Original Assignee
Kuraray Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kuraray Co Ltd filed Critical Kuraray Co Ltd
Publication of FR2452478A1 publication Critical patent/FR2452478A1/fr
Application granted granted Critical
Publication of FR2452478B1 publication Critical patent/FR2452478B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
    • C07D295/125—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/13—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D211/26—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/56—Nitrogen atoms
    • C07D211/58—Nitrogen atoms attached in position 4

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

COMPOSES DE TYPE AMIDE D'ACIDE FARNESYLACETIQUE DE FORMULE GENERALE: (CF DESSIN DANS BOPI) DANS LAQUELLE A EST UN RADICAL ALKYLENE D'AU MOINS 2ATOMES DE CARBONE, R EST UN ATOME D'HYDROGENE OU UN RADICAL ALKYLE INFERIEUR, ET R ET R SONT CHACUN, INDEPENDAMMENT, UN ATOME D'HYDROGENE, UN RADICAL ALKYLE, CYCLOALKYLE, ALKENYLE, ARYLE OU ARALKYLE, OU L'UN DE R ET R EST UN GROUPE QUI FORME, AVEC A, UN NOYAU PIPERIDINE CONTENANT EN TANT QU'ELEMENT CONSTITUTIF L'ATOME D'AZOTE SITUE ENTRE EUX, OU ENCORE R ET R, EN COMBINAISON, REPRESENTENT UN GROUPE QUI FORME, AVEC L'ATOME D'AZOTE AUQUEL ILS SONT LIES, UN NOYAU PIPERIDINE, PYRROLIDINE OU PIPERAZINE. CES COMPOSES, AINSI QUE LEURS SELS ACCEPTABLES DU POINT DE VUE PHARMACEUTIQUE, SONT UTILES EN TANT QU'AGENTS ANTIULCEROGENES ET AGENTS ANTIBACTERIENS.
FR8005931A 1979-03-28 1980-03-17 Amides d'acide farnesylacetique et leur utilisation en tant qu'agents anti-ulcereux et agents antibacteriens Granted FR2452478A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP3758579A JPS55129255A (en) 1979-03-28 1979-03-28 Farnesylacetamide compounds or their salts

Publications (2)

Publication Number Publication Date
FR2452478A1 true FR2452478A1 (fr) 1980-10-24
FR2452478B1 FR2452478B1 (fr) 1981-10-23

Family

ID=12501607

Family Applications (1)

Application Number Title Priority Date Filing Date
FR8005931A Granted FR2452478A1 (fr) 1979-03-28 1980-03-17 Amides d'acide farnesylacetique et leur utilisation en tant qu'agents anti-ulcereux et agents antibacteriens

Country Status (7)

Country Link
US (1) US4303588A (fr)
JP (1) JPS55129255A (fr)
CH (1) CH644353A5 (fr)
DE (1) DE3011504C2 (fr)
FR (1) FR2452478A1 (fr)
GB (1) GB2046745B (fr)
IT (1) IT1194641B (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0875501A2 (fr) * 1997-04-04 1998-11-04 Shiseido Company Limited Dérivé d'alkylène-diamines, médicament antiulcéreux et antibactérien

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5217979A (en) * 1989-09-22 1993-06-08 Merrell Dow Pharmaceuticals Inc. Substituted alkyl piperidines
CA2025490C (fr) * 1989-09-22 2003-09-16 James R. Mccarthy Alkyl piperidines subtituees et leur utilisation comme inhibiteurs de la synthese du cholesterol
US5350758A (en) * 1992-07-08 1994-09-27 Merrell Dow Pharmaceuticals Inc. Piperidyl sulfonamides and sulfoxamides as inhibitors of cholesterol biosynthesis
DE69700887T2 (de) * 1996-01-31 2000-06-29 Nisshin Flour Milling Co Isoprenderivate
US7053127B1 (en) * 2002-09-16 2006-05-30 Nalco Company Quaternized amido cyclic amine surfactant
US20050025823A1 (en) * 2003-07-29 2005-02-03 Fong Andy A.T. Methods of use of herbal compositions
US20080145409A1 (en) * 2006-12-19 2008-06-19 Min Chang Huang Composition for the treatment and prevention of peptic ulcer
PL2678307T3 (pl) * 2011-02-23 2018-11-30 Université D'aix-Marseille Zastosowanie pochodnych poliaminoizoprenylu w leczeniu antybiotykami lub środkami antyseptycznymi

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB833655A (en) * 1955-05-05 1960-04-27 Joseph Nichols Amides
FR1266607A (fr) * 1960-06-02 1961-07-17 Du Pont Additif pour carburants

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH122293A (de) * 1925-09-02 1927-09-01 Chem Ind Basel Verfahren zur Darstellung einer neuen Gallensäureverbindung.
BE578257A (fr) * 1958-04-30
US3646036A (en) * 1970-03-30 1972-02-29 Searle & Co 1-farnesylacetyl-4-hydroxyalkyl-piperazines

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB833655A (en) * 1955-05-05 1960-04-27 Joseph Nichols Amides
FR1266607A (fr) * 1960-06-02 1961-07-17 Du Pont Additif pour carburants

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
CA1965 *
CA1969 *

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0875501A2 (fr) * 1997-04-04 1998-11-04 Shiseido Company Limited Dérivé d'alkylène-diamines, médicament antiulcéreux et antibactérien
EP0875501A3 (fr) * 1997-04-04 1999-01-13 Shiseido Company Limited Dérivé d'alkylène-diamines, médicament antiulcéreux et antibactérien
US6001880A (en) * 1997-04-04 1999-12-14 Shiseido Co., Ltd. Alkylenediamine derivative, anti-ulcer drug, and antibacterial drug

Also Published As

Publication number Publication date
JPS6223742B2 (fr) 1987-05-25
GB2046745B (en) 1983-05-05
US4303588A (en) 1981-12-01
IT8020973A0 (it) 1980-03-27
IT1194641B (it) 1988-09-22
JPS55129255A (en) 1980-10-06
GB2046745A (en) 1980-11-19
DE3011504C2 (de) 1983-05-19
FR2452478B1 (fr) 1981-10-23
DE3011504A1 (de) 1980-10-02
CH644353A5 (fr) 1984-07-31

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