FR2439194A1 - Derives de la dibenzothiepine, leur procede de preparation et leur application therapeutique - Google Patents
Derives de la dibenzothiepine, leur procede de preparation et leur application therapeutiqueInfo
- Publication number
- FR2439194A1 FR2439194A1 FR7925685A FR7925685A FR2439194A1 FR 2439194 A1 FR2439194 A1 FR 2439194A1 FR 7925685 A FR7925685 A FR 7925685A FR 7925685 A FR7925685 A FR 7925685A FR 2439194 A1 FR2439194 A1 FR 2439194A1
- Authority
- FR
- France
- Prior art keywords
- preparation process
- therapeutic application
- dibenzothiepine
- derivatives
- dibenzothiepine derivatives
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- FKKFMCSXGHRBON-UHFFFAOYSA-N benzo[d][1]benzothiepine Chemical class S1C=CC2=CC=CC=C2C2=CC=CC=C12 FKKFMCSXGHRBON-UHFFFAOYSA-N 0.000 title abstract 2
- 238000002360 preparation method Methods 0.000 title 1
- 230000001225 therapeutic effect Effects 0.000 title 1
- -1 AMINO GROUP Chemical group 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-M hydroxide Chemical group [OH-] XLYOFNOQVPJJNP-UHFFFAOYSA-M 0.000 abstract 1
- 230000004968 inflammatory condition Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D337/00—Heterocyclic compounds containing rings of more than six members having one sulfur atom as the only ring hetero atom
- C07D337/02—Seven-membered rings
- C07D337/06—Seven-membered rings condensed with carbocyclic rings or ring systems
- C07D337/10—Seven-membered rings condensed with carbocyclic rings or ring systems condensed with two six-membered rings
- C07D337/14—[b,f]-condensed
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP12684678A JPS5553282A (en) | 1978-10-17 | 1978-10-17 | Dibenzothiepin derivative and its preparation |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FR2439194A1 true FR2439194A1 (fr) | 1980-05-16 |
| FR2439194B1 FR2439194B1 (US06815460-20041109-C00103.png) | 1984-02-03 |
Family
ID=14945305
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR7925685A Granted FR2439194A1 (fr) | 1978-10-17 | 1979-10-16 | Derives de la dibenzothiepine, leur procede de preparation et leur application therapeutique |
Country Status (9)
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0309626A1 (en) * | 1987-09-30 | 1989-04-05 | Nippon Chemiphar Co., Ltd. | Process for the preparation of dibenzothiepin derivative |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4536507A (en) * | 1977-07-26 | 1985-08-20 | Merck & Co., Inc. | Prostaglandin antagonists |
| JPS54115388A (en) * | 1978-03-01 | 1979-09-07 | Nippon Chemiphar Co Ltd | Acetic acid derivative and its preparation |
| JPS57106678A (en) * | 1980-12-23 | 1982-07-02 | Nippon Chemiphar Co Ltd | Preparation of dibenzothiepinpropionic acid derivative |
| JPS57106656A (en) * | 1980-12-23 | 1982-07-02 | Nippon Chemiphar Co Ltd | Phenylthiophenylacetic acid derivative |
| JPS58113168A (ja) * | 1981-12-28 | 1983-07-05 | Fuji Photo Film Co Ltd | ５−（１−カルボキシエチル）−２−フエニルチオフエニル酢酸の製造法 |
| JPS58203986A (ja) * | 1982-05-20 | 1983-11-28 | Nippon Chemiphar Co Ltd | 光学活性ジベンゾチエピン酸を含有する薬剤 |
| US4891433A (en) * | 1986-06-10 | 1990-01-02 | Nippon Chemiphar Co., Ltd. | Process for the preparation of dibenzothiepin derivative |
| CN1095840C (zh) * | 1996-08-22 | 2002-12-11 | 日本化学医药株式会社 | 2－(10,11－二氢－10－氧代二苯并[b,f]噻庚英－2－基)丙酸的制备方法及其中间体化合物 |
| IT1308633B1 (it) | 1999-03-02 | 2002-01-09 | Nicox Sa | Nitrossiderivati. |
| KR100898099B1 (ko) | 2007-05-28 | 2009-05-15 | 주식회사 엔지켐 | 잘토프로펜의 제조방법 |
| WO2013161842A1 (ja) | 2012-04-24 | 2013-10-31 | 日本ケミファ株式会社 | ザルトプロフェンおよびその誘導体の製造方法 |
| KR20200077911A (ko) | 2018-12-21 | 2020-07-01 | (주)유케이케미팜 | 잘토프로펜 함유 서방성 의약 조성물 |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL7713373A (nl) * | 1976-12-03 | 1978-06-06 | Nippon Chemiphar Co | Werkwijze voor de bereiding en toepassing van propionzuurderivaten. |
| EP0003893A1 (en) * | 1978-02-17 | 1979-09-05 | Dainippon Pharmaceutical Co., Ltd. | Novel dibenz (b,f) oxepin and dibenzo (b,f) thiepin compounds and pharmaceutically acceptable salts thereof, processes for their preparation and pharmaceutical compositions containing them |
| GB2016466A (en) * | 1978-03-01 | 1979-09-26 | Nippon Chemiphar Co | Acetic acid derivatives and processes for producing the same |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4101667A (en) * | 1975-05-30 | 1978-07-18 | Nippon Chemiphar Co., Ltd. | Benzo[b,f]thiepin derivatives |
| US4104280A (en) * | 1977-02-04 | 1978-08-01 | Syntex (U.S.A.) Inc. | Dibenzo [b.f]thiepin and dibenzo[b.f]oxepin derivatives |
-
1978
- 1978-10-17 JP JP12684678A patent/JPS5553282A/ja active Granted
-
1979
- 1979-10-12 US US06/084,163 patent/US4247706A/en not_active Expired - Lifetime
- 1979-10-16 IT IT69010/79A patent/IT1121483B/it active
- 1979-10-16 DE DE19792941869 patent/DE2941869A1/de active Granted
- 1979-10-16 GB GB7935949A patent/GB2035311B/en not_active Expired
- 1979-10-16 CH CH929879A patent/CH641798A5/fr not_active IP Right Cessation
- 1979-10-16 FR FR7925685A patent/FR2439194A1/fr active Granted
- 1979-10-16 CA CA337,710A patent/CA1127165A/en not_active Expired
- 1979-10-17 ES ES485098A patent/ES485098A1/es not_active Expired
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL7713373A (nl) * | 1976-12-03 | 1978-06-06 | Nippon Chemiphar Co | Werkwijze voor de bereiding en toepassing van propionzuurderivaten. |
| FR2372836A1 (fr) * | 1976-12-03 | 1978-06-30 | Nippon Chemiphar Co | Derives de l'acide propionique, leurs procedes de preparation et leur application en therapeutique |
| EP0003893A1 (en) * | 1978-02-17 | 1979-09-05 | Dainippon Pharmaceutical Co., Ltd. | Novel dibenz (b,f) oxepin and dibenzo (b,f) thiepin compounds and pharmaceutically acceptable salts thereof, processes for their preparation and pharmaceutical compositions containing them |
| GB2016466A (en) * | 1978-03-01 | 1979-09-26 | Nippon Chemiphar Co | Acetic acid derivatives and processes for producing the same |
Non-Patent Citations (1)
| Title |
|---|
| EXBK/78 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0309626A1 (en) * | 1987-09-30 | 1989-04-05 | Nippon Chemiphar Co., Ltd. | Process for the preparation of dibenzothiepin derivative |
Also Published As
| Publication number | Publication date |
|---|---|
| ES485098A1 (es) | 1980-09-01 |
| IT1121483B (it) | 1986-04-02 |
| JPS5553282A (en) | 1980-04-18 |
| US4247706A (en) | 1981-01-27 |
| CA1127165A (en) | 1982-07-06 |
| DE2941869C2 (US06815460-20041109-C00103.png) | 1988-07-21 |
| CH641798A5 (fr) | 1984-03-15 |
| GB2035311A (en) | 1980-06-18 |
| GB2035311B (en) | 1982-07-14 |
| IT7969010A0 (it) | 1979-10-16 |
| JPS617199B2 (US06815460-20041109-C00103.png) | 1986-03-04 |
| DE2941869A1 (de) | 1980-04-30 |
| FR2439194B1 (US06815460-20041109-C00103.png) | 1984-02-03 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ST | Notification of lapse |