FR2434155A1 - Derives d'imidazole et leur utilisation pour le traitement des maladies provoquees par le thromboxane a2 - Google Patents
Derives d'imidazole et leur utilisation pour le traitement des maladies provoquees par le thromboxane a2Info
- Publication number
- FR2434155A1 FR2434155A1 FR7920965A FR7920965A FR2434155A1 FR 2434155 A1 FR2434155 A1 FR 2434155A1 FR 7920965 A FR7920965 A FR 7920965A FR 7920965 A FR7920965 A FR 7920965A FR 2434155 A1 FR2434155 A1 FR 2434155A1
- Authority
- FR
- France
- Prior art keywords
- thromboxane
- diseases
- treatment
- imidazole derivatives
- derivatives
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Immunology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Pulmonology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
L'invention a pour objet des dérivés d'imidazole. Ces dérivés répondent à la formule :
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP53101549A JPS5951943B2 (ja) | 1978-08-21 | 1978-08-21 | 新規なイミダゾ−ル誘導体 |
Publications (2)
Publication Number | Publication Date |
---|---|
FR2434155A1 true FR2434155A1 (fr) | 1980-03-21 |
FR2434155B1 FR2434155B1 (fr) | 1983-06-24 |
Family
ID=14303503
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR7920965A Granted FR2434155A1 (fr) | 1978-08-21 | 1979-08-20 | Derives d'imidazole et leur utilisation pour le traitement des maladies provoquees par le thromboxane a2 |
Country Status (6)
Country | Link |
---|---|
US (1) | US4632934A (fr) |
JP (1) | JPS5951943B2 (fr) |
DE (1) | DE2933649A1 (fr) |
FR (1) | FR2434155A1 (fr) |
GB (1) | GB2031408B (fr) |
IT (1) | IT1164699B (fr) |
Cited By (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2444031A1 (fr) * | 1978-12-13 | 1980-07-11 | Pfizer | Nouveaux derives d'imidazole, leur procede de production et composition pharmaceutique les contenant |
FR2446828A1 (fr) * | 1979-01-19 | 1980-08-14 | Pfizer | N-benzylimidazoles inhibiteurs selectifs de thromboxanne-synthetase, leur procede de production et compositions pharmaceutiques les contenant |
FR2495614A1 (fr) * | 1980-12-05 | 1982-06-11 | Shionogi & Co | Procede de preparation de composes de 1-benzylimidazole, nouveaux produits ainsi obtenus et leur utilisation comme fongicides et pour le traitement antimycose des etres humains ou des animaux |
EP0066144A2 (fr) * | 1981-05-14 | 1982-12-08 | Shionogi & Co., Ltd. | Dérivés de benzylazole |
FR2512020A1 (fr) * | 1981-08-29 | 1983-03-04 | Kissei Pharmaceutical | Derives d'imidazole et procede de preparation de ceux-ci |
EP0077037A1 (fr) * | 1981-10-09 | 1983-04-20 | Sumitomo Chemical Company, Limited | Acides imidazolylcarboxiliques, leurs dérivés et leur préparation |
EP0558062A2 (fr) * | 1992-02-28 | 1993-09-01 | Ono Pharmaceutical Co., Ltd. | Dérivés d'acide phénoxyacétique et compositions pharmaceutiques les contenant |
Families Citing this family (23)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GR71915B (fr) * | 1979-11-27 | 1983-08-16 | Pfizer | |
JPS56113766A (en) * | 1980-02-12 | 1981-09-07 | Teijin Ltd | Novel 1-substituted imidazole derivative and its preparation |
US4350696A (en) | 1980-03-08 | 1982-09-21 | Pfizer Inc. | Imidazole derivatives, process for their preparation and pharmaceutical compositions thereof |
CS229934B2 (en) * | 1981-07-07 | 1984-07-16 | Pfizer | Production method subst.indolylacryte acid derivative |
DE3130252A1 (de) * | 1981-07-31 | 1983-02-17 | A. Nattermann & Cie GmbH, 5000 Köln | 6-(5-((omega)-(1-imidazolyl)-alkyl)-thien-2-yl)-3-oxo-2,3,4,5-tetrahydro-pyridazine und deren saeureadditionssalze, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate |
DE3369984D1 (en) * | 1982-07-12 | 1987-04-09 | Searle & Co | 1-(1h-imidazolyl), 1-n-morpholinyl and pyridyl compounds, their preparation and pharmaceutical compositions containing them |
DE3228266A1 (de) | 1982-07-29 | 1984-02-02 | A. Nattermann & Cie GmbH, 5000 Köln | Imidazolylalkylthiophene, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate |
ES533668A0 (es) * | 1983-06-24 | 1985-10-01 | Yamanouchi Pharma Co Ltd | Un compuesto fenoxi |
US4894385A (en) * | 1985-01-16 | 1990-01-16 | Sankyo Company Limited | Imidazole derivatives as inhibitors of TXA2 synthesis |
US4758580A (en) * | 1985-06-26 | 1988-07-19 | Yamanouchi Pharmaceutical Co., Ltd. | Inhibiting growth of tumors with certain substituted phenoxy dimethyl alkanoic acids, esters or salts |
US5294722A (en) * | 1992-04-16 | 1994-03-15 | E. R. Squibb & Sons, Inc. | Process for the preparation of imidazoles useful in angiotensin II antagonism |
JP2867201B2 (ja) * | 1993-02-26 | 1999-03-08 | ローレルバンクマシン株式会社 | 硬貨包装機における包装紙確認装置 |
US6300514B1 (en) | 1997-06-25 | 2001-10-09 | Ono Pharmaceutical Co., Ltd. | Aryl (sulfide, sulfoxide and sulfone) derivatives and drugs containing the same as the active ingredient |
HUP0100860A3 (en) * | 1997-12-11 | 2003-03-28 | Janssen Pharmaceutica Nv | Retinoic acid mimetic anilides, process for their preparation and pharmaceutical compositions containing them |
SE0301010D0 (sv) | 2003-04-07 | 2003-04-07 | Astrazeneca Ab | Novel compounds |
SE0302281D0 (sv) * | 2003-08-21 | 2003-08-21 | Astrazeneca Ab | Novel compounds |
SA04250253B1 (ar) * | 2003-08-21 | 2009-11-10 | استرازينيكا ايه بي | احماض فينوكسي اسيتيك مستبدلة باعتبارها مركبات صيدلانية لعلاج الامراض التنفسية مثل الربو ومرض الانسداد الرئوي المزمن |
GB0415320D0 (en) | 2004-07-08 | 2004-08-11 | Astrazeneca Ab | Novel compounds |
GB0418830D0 (en) | 2004-08-24 | 2004-09-22 | Astrazeneca Ab | Novel compounds |
JP5208510B2 (ja) | 2004-11-23 | 2013-06-12 | アストラゼネカ・アクチエボラーグ | 呼吸器疾患の処置に有用なフェノキシ酢酸誘導体 |
TW200745003A (en) | 2005-10-06 | 2007-12-16 | Astrazeneca Ab | Novel compounds |
US8148572B2 (en) | 2005-10-06 | 2012-04-03 | Astrazeneca Ab | Compounds |
UA100983C2 (ru) | 2007-07-05 | 2013-02-25 | Астразенека Аб | Бифенилоксипропановая кислота как модулятор crth2 и интермедиаты |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2267101A1 (fr) * | 1974-04-11 | 1975-11-07 | Schering Ag | |
FR2299807A1 (fr) * | 1975-02-05 | 1976-09-03 | Rohm & Haas | Produits et composit |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4017631A (en) * | 1974-11-19 | 1977-04-12 | Janssen Pharmaceutica N.V. | Imidazolium salts |
US4101665A (en) * | 1975-10-06 | 1978-07-18 | Janssen Pharmaceutica N.V. | 1-(2-Ar-4-aryloxymethyl-1,3-dioxolan-2-ylmethyl)imidazoles |
-
1978
- 1978-08-21 JP JP53101549A patent/JPS5951943B2/ja not_active Expired
-
1979
- 1979-08-14 IT IT50045/79A patent/IT1164699B/it active
- 1979-08-14 GB GB7928275A patent/GB2031408B/en not_active Expired
- 1979-08-20 FR FR7920965A patent/FR2434155A1/fr active Granted
- 1979-08-20 DE DE19792933649 patent/DE2933649A1/de active Granted
- 1979-08-21 US US06/068,365 patent/US4632934A/en not_active Expired - Lifetime
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2267101A1 (fr) * | 1974-04-11 | 1975-11-07 | Schering Ag | |
FR2299807A1 (fr) * | 1975-02-05 | 1976-09-03 | Rohm & Haas | Produits et composit |
Cited By (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2444031A1 (fr) * | 1978-12-13 | 1980-07-11 | Pfizer | Nouveaux derives d'imidazole, leur procede de production et composition pharmaceutique les contenant |
FR2446828A1 (fr) * | 1979-01-19 | 1980-08-14 | Pfizer | N-benzylimidazoles inhibiteurs selectifs de thromboxanne-synthetase, leur procede de production et compositions pharmaceutiques les contenant |
FR2495614A1 (fr) * | 1980-12-05 | 1982-06-11 | Shionogi & Co | Procede de preparation de composes de 1-benzylimidazole, nouveaux produits ainsi obtenus et leur utilisation comme fongicides et pour le traitement antimycose des etres humains ou des animaux |
EP0066144A2 (fr) * | 1981-05-14 | 1982-12-08 | Shionogi & Co., Ltd. | Dérivés de benzylazole |
EP0066144A3 (en) * | 1981-05-14 | 1983-11-30 | Shionogi & Co., Ltd. | Benzylazole derivatives |
FR2512020A1 (fr) * | 1981-08-29 | 1983-03-04 | Kissei Pharmaceutical | Derives d'imidazole et procede de preparation de ceux-ci |
EP0077037A1 (fr) * | 1981-10-09 | 1983-04-20 | Sumitomo Chemical Company, Limited | Acides imidazolylcarboxiliques, leurs dérivés et leur préparation |
US4461774A (en) * | 1981-10-09 | 1984-07-24 | Sumitomo Chemical Company, Limited | Antifungal imidazolylcarboxylic acids and their derivatives |
EP0558062A2 (fr) * | 1992-02-28 | 1993-09-01 | Ono Pharmaceutical Co., Ltd. | Dérivés d'acide phénoxyacétique et compositions pharmaceutiques les contenant |
EP0558062A3 (fr) * | 1992-02-28 | 1994-01-12 | Ono Pharmaceutical Co | |
US5935985A (en) * | 1992-02-28 | 1999-08-10 | Ono Pharmaceutical Co., Ltd. | Phenoxyacetic acid derivatives |
Also Published As
Publication number | Publication date |
---|---|
FR2434155B1 (fr) | 1983-06-24 |
IT7950045A0 (it) | 1979-08-14 |
GB2031408A (en) | 1980-04-23 |
DE2933649A1 (de) | 1980-03-13 |
JPS5951943B2 (ja) | 1984-12-17 |
DE2933649C2 (fr) | 1988-09-15 |
GB2031408B (en) | 1983-03-02 |
US4632934A (en) | 1986-12-30 |
IT1164699B (it) | 1987-04-15 |
JPS5528927A (en) | 1980-02-29 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
ST | Notification of lapse |