FR2434155A1 - Derives d'imidazole et leur utilisation pour le traitement des maladies provoquees par le thromboxane a2 - Google Patents

Derives d'imidazole et leur utilisation pour le traitement des maladies provoquees par le thromboxane a2

Info

Publication number
FR2434155A1
FR2434155A1 FR7920965A FR7920965A FR2434155A1 FR 2434155 A1 FR2434155 A1 FR 2434155A1 FR 7920965 A FR7920965 A FR 7920965A FR 7920965 A FR7920965 A FR 7920965A FR 2434155 A1 FR2434155 A1 FR 2434155A1
Authority
FR
France
Prior art keywords
thromboxane
diseases
treatment
imidazole derivatives
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7920965A
Other languages
English (en)
Other versions
FR2434155B1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kissei Pharmaceutical Co Ltd
Original Assignee
Kissei Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=14303503&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=FR2434155(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Kissei Pharmaceutical Co Ltd filed Critical Kissei Pharmaceutical Co Ltd
Publication of FR2434155A1 publication Critical patent/FR2434155A1/fr
Application granted granted Critical
Publication of FR2434155B1 publication Critical patent/FR2434155B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Immunology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

L'invention a pour objet des dérivés d'imidazole. Ces dérivés répondent à la formule :
FR7920965A 1978-08-21 1979-08-20 Derives d'imidazole et leur utilisation pour le traitement des maladies provoquees par le thromboxane a2 Granted FR2434155A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP53101549A JPS5951943B2 (ja) 1978-08-21 1978-08-21 新規なイミダゾ−ル誘導体

Publications (2)

Publication Number Publication Date
FR2434155A1 true FR2434155A1 (fr) 1980-03-21
FR2434155B1 FR2434155B1 (fr) 1983-06-24

Family

ID=14303503

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7920965A Granted FR2434155A1 (fr) 1978-08-21 1979-08-20 Derives d'imidazole et leur utilisation pour le traitement des maladies provoquees par le thromboxane a2

Country Status (6)

Country Link
US (1) US4632934A (fr)
JP (1) JPS5951943B2 (fr)
DE (1) DE2933649A1 (fr)
FR (1) FR2434155A1 (fr)
GB (1) GB2031408B (fr)
IT (1) IT1164699B (fr)

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2444031A1 (fr) * 1978-12-13 1980-07-11 Pfizer Nouveaux derives d'imidazole, leur procede de production et composition pharmaceutique les contenant
FR2446828A1 (fr) * 1979-01-19 1980-08-14 Pfizer N-benzylimidazoles inhibiteurs selectifs de thromboxanne-synthetase, leur procede de production et compositions pharmaceutiques les contenant
FR2495614A1 (fr) * 1980-12-05 1982-06-11 Shionogi & Co Procede de preparation de composes de 1-benzylimidazole, nouveaux produits ainsi obtenus et leur utilisation comme fongicides et pour le traitement antimycose des etres humains ou des animaux
EP0066144A2 (fr) * 1981-05-14 1982-12-08 Shionogi & Co., Ltd. Dérivés de benzylazole
FR2512020A1 (fr) * 1981-08-29 1983-03-04 Kissei Pharmaceutical Derives d'imidazole et procede de preparation de ceux-ci
EP0077037A1 (fr) * 1981-10-09 1983-04-20 Sumitomo Chemical Company, Limited Acides imidazolylcarboxiliques, leurs dérivés et leur préparation
EP0558062A2 (fr) * 1992-02-28 1993-09-01 Ono Pharmaceutical Co., Ltd. Dérivés d'acide phénoxyacétique et compositions pharmaceutiques les contenant

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GR71915B (fr) * 1979-11-27 1983-08-16 Pfizer
JPS56113766A (en) * 1980-02-12 1981-09-07 Teijin Ltd Novel 1-substituted imidazole derivative and its preparation
US4350696A (en) 1980-03-08 1982-09-21 Pfizer Inc. Imidazole derivatives, process for their preparation and pharmaceutical compositions thereof
CS229934B2 (en) * 1981-07-07 1984-07-16 Pfizer Production method subst.indolylacryte acid derivative
DE3130252A1 (de) * 1981-07-31 1983-02-17 A. Nattermann & Cie GmbH, 5000 Köln 6-(5-((omega)-(1-imidazolyl)-alkyl)-thien-2-yl)-3-oxo-2,3,4,5-tetrahydro-pyridazine und deren saeureadditionssalze, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate
DE3369984D1 (en) * 1982-07-12 1987-04-09 Searle & Co 1-(1h-imidazolyl), 1-n-morpholinyl and pyridyl compounds, their preparation and pharmaceutical compositions containing them
DE3228266A1 (de) 1982-07-29 1984-02-02 A. Nattermann & Cie GmbH, 5000 Köln Imidazolylalkylthiophene, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate
ES533668A0 (es) * 1983-06-24 1985-10-01 Yamanouchi Pharma Co Ltd Un compuesto fenoxi
US4894385A (en) * 1985-01-16 1990-01-16 Sankyo Company Limited Imidazole derivatives as inhibitors of TXA2 synthesis
US4758580A (en) * 1985-06-26 1988-07-19 Yamanouchi Pharmaceutical Co., Ltd. Inhibiting growth of tumors with certain substituted phenoxy dimethyl alkanoic acids, esters or salts
US5294722A (en) * 1992-04-16 1994-03-15 E. R. Squibb & Sons, Inc. Process for the preparation of imidazoles useful in angiotensin II antagonism
JP2867201B2 (ja) * 1993-02-26 1999-03-08 ローレルバンクマシン株式会社 硬貨包装機における包装紙確認装置
US6300514B1 (en) 1997-06-25 2001-10-09 Ono Pharmaceutical Co., Ltd. Aryl (sulfide, sulfoxide and sulfone) derivatives and drugs containing the same as the active ingredient
HUP0100860A3 (en) * 1997-12-11 2003-03-28 Janssen Pharmaceutica Nv Retinoic acid mimetic anilides, process for their preparation and pharmaceutical compositions containing them
SE0301010D0 (sv) 2003-04-07 2003-04-07 Astrazeneca Ab Novel compounds
SE0302281D0 (sv) * 2003-08-21 2003-08-21 Astrazeneca Ab Novel compounds
SA04250253B1 (ar) * 2003-08-21 2009-11-10 استرازينيكا ايه بي احماض فينوكسي اسيتيك مستبدلة باعتبارها مركبات صيدلانية لعلاج الامراض التنفسية مثل الربو ومرض الانسداد الرئوي المزمن
GB0415320D0 (en) 2004-07-08 2004-08-11 Astrazeneca Ab Novel compounds
GB0418830D0 (en) 2004-08-24 2004-09-22 Astrazeneca Ab Novel compounds
JP5208510B2 (ja) 2004-11-23 2013-06-12 アストラゼネカ・アクチエボラーグ 呼吸器疾患の処置に有用なフェノキシ酢酸誘導体
TW200745003A (en) 2005-10-06 2007-12-16 Astrazeneca Ab Novel compounds
US8148572B2 (en) 2005-10-06 2012-04-03 Astrazeneca Ab Compounds
UA100983C2 (ru) 2007-07-05 2013-02-25 Астразенека Аб Бифенилоксипропановая кислота как модулятор crth2 и интермедиаты

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2267101A1 (fr) * 1974-04-11 1975-11-07 Schering Ag
FR2299807A1 (fr) * 1975-02-05 1976-09-03 Rohm & Haas Produits et composit

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4017631A (en) * 1974-11-19 1977-04-12 Janssen Pharmaceutica N.V. Imidazolium salts
US4101665A (en) * 1975-10-06 1978-07-18 Janssen Pharmaceutica N.V. 1-(2-Ar-4-aryloxymethyl-1,3-dioxolan-2-ylmethyl)imidazoles

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2267101A1 (fr) * 1974-04-11 1975-11-07 Schering Ag
FR2299807A1 (fr) * 1975-02-05 1976-09-03 Rohm & Haas Produits et composit

Cited By (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2444031A1 (fr) * 1978-12-13 1980-07-11 Pfizer Nouveaux derives d'imidazole, leur procede de production et composition pharmaceutique les contenant
FR2446828A1 (fr) * 1979-01-19 1980-08-14 Pfizer N-benzylimidazoles inhibiteurs selectifs de thromboxanne-synthetase, leur procede de production et compositions pharmaceutiques les contenant
FR2495614A1 (fr) * 1980-12-05 1982-06-11 Shionogi & Co Procede de preparation de composes de 1-benzylimidazole, nouveaux produits ainsi obtenus et leur utilisation comme fongicides et pour le traitement antimycose des etres humains ou des animaux
EP0066144A2 (fr) * 1981-05-14 1982-12-08 Shionogi & Co., Ltd. Dérivés de benzylazole
EP0066144A3 (en) * 1981-05-14 1983-11-30 Shionogi & Co., Ltd. Benzylazole derivatives
FR2512020A1 (fr) * 1981-08-29 1983-03-04 Kissei Pharmaceutical Derives d'imidazole et procede de preparation de ceux-ci
EP0077037A1 (fr) * 1981-10-09 1983-04-20 Sumitomo Chemical Company, Limited Acides imidazolylcarboxiliques, leurs dérivés et leur préparation
US4461774A (en) * 1981-10-09 1984-07-24 Sumitomo Chemical Company, Limited Antifungal imidazolylcarboxylic acids and their derivatives
EP0558062A2 (fr) * 1992-02-28 1993-09-01 Ono Pharmaceutical Co., Ltd. Dérivés d'acide phénoxyacétique et compositions pharmaceutiques les contenant
EP0558062A3 (fr) * 1992-02-28 1994-01-12 Ono Pharmaceutical Co
US5935985A (en) * 1992-02-28 1999-08-10 Ono Pharmaceutical Co., Ltd. Phenoxyacetic acid derivatives

Also Published As

Publication number Publication date
FR2434155B1 (fr) 1983-06-24
IT7950045A0 (it) 1979-08-14
GB2031408A (en) 1980-04-23
DE2933649A1 (de) 1980-03-13
JPS5951943B2 (ja) 1984-12-17
DE2933649C2 (fr) 1988-09-15
GB2031408B (en) 1983-03-02
US4632934A (en) 1986-12-30
IT1164699B (it) 1987-04-15
JPS5528927A (en) 1980-02-29

Similar Documents

Publication Publication Date Title
FR2434155A1 (fr) Derives d'imidazole et leur utilisation pour le traitement des maladies provoquees par le thromboxane a2
FR2435248A1 (fr) Derives de 4-anilinoquinazoline, leur procede de preparation et leur application en therapeutique
FR2372810A1 (fr) Nouvelles aminoalcoylimidazolidinones, procedes pour leur preparation et leur utilisation en tant que medicaments
FR2433515A1 (fr) Acides pyrrolidinecarboxyliques-2 utiles comme antihypertenseurs
FR2430406A1 (fr) Complexes platine-diamine, procede d'obtention, application d'un complexe pour l'obtention d'un medicament pour le traitement du cancer et medicament ainsi obtenu
FR2383157A1 (fr) Derives de chalcone, leur procede de preparation et leur application en therapeutique
FR2392671A1 (fr) Application pharmacologique des acides d2-3-1,4-morpholine-2-carboxyliques substitues
FR2383922A1 (fr) Nouvelles 4-acylamino-phenyl-ethanolamines, procede pour leur preparation et leur utilisation en tant que medicaments
FR2405246A1 (fr) Nouveaux derives de pyrrole, leur procede de preparation et leurs applications en therapeutique
FR2445834A1 (fr) Derives heterobicycliques de l'acide 7-acylamido-3-cephem-4-carboxylique insature, procedes de preparation de ceux-ci et utilisation en therapeutique
FR2453151A1 (fr) Derives de la vitamine d3, leur procede de preparation et leur application en therapeutique
FR2442819A1 (fr) Alcools b,g-dihydropolyprenyliques, leur procede de preparation et leurs applications therapeutiques
FR2378014A1 (fr) Nouveaux derives aminoalcoxyphenyles, leur preparation et leur utilisation en tant que medicaments
FR2445328A1 (fr) Derives du 14-oxo-e-homo-eburnane, leur procede de preparation et leur utilisation comme medicament
FR2372165A1 (fr)
FR2358384A1 (fr) Peptides psychopharmacologiquement actifs et derives de ces peptides
FR2403336A1 (fr) Derives de 3,4-dihydrocarbostyrile, leur procede de preparation et leur utilisation pour le traitement des troubles cardiaques
FR2383944A1 (fr) Derives de bis-benzimidazolyle substitues, leur procede de preparation et leur application en therapeutique
FR2355831A1 (fr) Derives de benzazocine, leur procede de preparation et leur application therapeutique
FR2400017A1 (fr) Nouveaux acides 2-pyridyl- et 2-pyrimidylaminobenzoiques, leur preparation et leur utilisation en tant que medicaments
BE872908A (fr) Compositions pharmaceutiques pour le traitement de l'hypertension
FR2453163A1 (fr) Derives de benzothiazole, leur procede de preparation et leurs applications en therapeutique
FR2442827A1 (fr) Nouveaux acides oxy-cyclohexylacetiques substitues, leur procede de preparation et leur application en therapeutique
FR2378017A1 (fr) Alkylthio-7,8-dihydroxy-1-phenyl-2,3,4,5-tetrahydro-1h-3-benzazepines, leur procede de preparation et application en therapeutique
FR2355846A1 (fr) Esters de penicillines utilisables comme medicaments

Legal Events

Date Code Title Description
ST Notification of lapse