FR2432021A1 - Nouveaux esters amines d'acide indane-acetique et leur utilisation en therapeutique - Google Patents

Nouveaux esters amines d'acide indane-acetique et leur utilisation en therapeutique

Info

Publication number
FR2432021A1
FR2432021A1 FR7821849A FR7821849A FR2432021A1 FR 2432021 A1 FR2432021 A1 FR 2432021A1 FR 7821849 A FR7821849 A FR 7821849A FR 7821849 A FR7821849 A FR 7821849A FR 2432021 A1 FR2432021 A1 FR 2432021A1
Authority
FR
France
Prior art keywords
indanyl
low toxicity
analgesics
piperazinyl
phenyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7821849A
Other languages
English (en)
Other versions
FR2432021B1 (fr
Inventor
Jean-Marie Teulon
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hexachimie SA
Original Assignee
Hexachimie SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hexachimie SA filed Critical Hexachimie SA
Priority to FR7821849A priority Critical patent/FR2432021A1/fr
Priority to GR59316A priority patent/GR65999B/el
Priority to GB8002206A priority patent/GB2038830A/en
Priority to GB7923195A priority patent/GB2027019B/en
Priority to GB08210290A priority patent/GB2103599B/en
Priority to AR277223A priority patent/AR220210A1/es
Priority to US06/055,907 priority patent/US4271161A/en
Priority to CA331,498A priority patent/CA1125756A/fr
Priority to EP79400500A priority patent/EP0008256A3/fr
Priority to EP81103269A priority patent/EP0034838A3/fr
Priority to PT69941A priority patent/PT69941A/fr
Priority to AU49019/79A priority patent/AU516742B2/en
Priority to ES482656A priority patent/ES8101063A1/es
Priority to PH22804A priority patent/PH14387A/en
Priority to BE2/57972A priority patent/BE877825A/fr
Priority to ZA00793743A priority patent/ZA793743B/xx
Priority to JP9330879A priority patent/JPS5519279A/ja
Publication of FR2432021A1 publication Critical patent/FR2432021A1/fr
Priority to ES492085A priority patent/ES8104254A1/es
Priority to AR282297A priority patent/AR220500A1/es
Priority to AU70050/81A priority patent/AU7005081A/en
Application granted granted Critical
Publication of FR2432021B1 publication Critical patent/FR2432021B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/58—Preparation of carboxylic acid halides
    • C07C51/60—Preparation of carboxylic acid halides by conversion of carboxylic acids or their anhydrides or esters, lactones, salts into halides with the same carboxylic acid part

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pain & Pain Management (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Nouveaux composés de formule :
FR7821849A 1978-07-24 1978-07-24 Nouveaux esters amines d'acide indane-acetique et leur utilisation en therapeutique Granted FR2432021A1 (fr)

Priority Applications (20)

Application Number Priority Date Filing Date Title
FR7821849A FR2432021A1 (fr) 1978-07-24 1978-07-24 Nouveaux esters amines d'acide indane-acetique et leur utilisation en therapeutique
GR59316A GR65999B (fr) 1978-07-24 1979-06-09
GB8002206A GB2038830A (en) 1978-07-24 1979-07-03 Indane acetic acid haloesters
GB7923195A GB2027019B (en) 1978-07-24 1979-07-03 New indaneacetic acid aminoesters and their use in therapy
GB08210290A GB2103599B (en) 1978-07-24 1979-07-03 Indane acetic acid haloesters
AR277223A AR220210A1 (es) 1978-07-24 1979-07-06 Procedimiento para preparar ester m-trifluormetilfenilpiperazino etilico del acido 2-metil-(5-(2-etil o isopropil)indanil)acetico
US06/055,907 US4271161A (en) 1978-07-24 1979-07-09 Indane-acetic acid aminoesters, their preparation and their use in therapy
CA331,498A CA1125756A (fr) 1978-07-24 1979-07-10 Obtention et applications therapeutiques d'aminoesters d'indane et d'acide acetique
EP81103269A EP0034838A3 (fr) 1978-07-24 1979-07-13 Nouveaux esters halogénoéthyliques d'acide indane acétique, et leur préparation
EP79400500A EP0008256A3 (fr) 1978-07-24 1979-07-13 Nouveaux esters d'acide indane-acétique, leur préparation et médicaments les contenant
PT69941A PT69941A (fr) 1978-07-24 1979-07-18 Procede de preparation de nouveaux esters amines d'acide indane-acetique utiles en therapeutique
AU49019/79A AU516742B2 (en) 1978-07-24 1979-07-18 Indane-acetic acid aminoesters
ES482656A ES8101063A1 (es) 1978-07-24 1979-07-19 Un procedimiento para la preparacion de nuesvos esteres ami-nados del indano.
BE2/57972A BE877825A (fr) 1978-07-24 1979-07-23 Nouveaux esters amines d'acide indaneacetique et leur utilisation en therapeutique
ZA00793743A ZA793743B (en) 1978-07-24 1979-07-23 New indane-acetic acid aminoesters,their preparation and their use in therapy
PH22804A PH14387A (en) 1978-07-24 1979-07-23 Indane-acetic acid aminoester derivative
JP9330879A JPS5519279A (en) 1978-07-24 1979-07-24 Indannacetic acid amino ester and its manufacture
ES492085A ES8104254A1 (es) 1978-07-24 1980-06-02 Un procedimiento para la preparacion de nuevos esteres ami- nados del indano
AR282297A AR220500A1 (es) 1978-07-24 1980-08-26 Procedimiento para preparar ester m-trifluormetilfenilpiperazino etilico del acido 2-metil-(5-(2-etil o isopropil)indanil)acetico
AU70050/81A AU7005081A (en) 1978-07-24 1981-05-01 Indane halogenoesters

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7821849A FR2432021A1 (fr) 1978-07-24 1978-07-24 Nouveaux esters amines d'acide indane-acetique et leur utilisation en therapeutique

Publications (2)

Publication Number Publication Date
FR2432021A1 true FR2432021A1 (fr) 1980-02-22
FR2432021B1 FR2432021B1 (fr) 1981-07-24

Family

ID=9211085

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7821849A Granted FR2432021A1 (fr) 1978-07-24 1978-07-24 Nouveaux esters amines d'acide indane-acetique et leur utilisation en therapeutique

Country Status (4)

Country Link
JP (1) JPS5519279A (fr)
BE (1) BE877825A (fr)
FR (1) FR2432021A1 (fr)
ZA (1) ZA793743B (fr)

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2250334A6 (fr) * 1971-09-07 1975-05-30 Orenstein & Koppel Ag
FR2258940A1 (fr) * 1974-01-29 1975-08-22 Spiroll Corp Ltd

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2250334A6 (fr) * 1971-09-07 1975-05-30 Orenstein & Koppel Ag
FR2258940A1 (fr) * 1974-01-29 1975-08-22 Spiroll Corp Ltd

Also Published As

Publication number Publication date
BE877825A (fr) 1980-01-23
JPS5519279A (en) 1980-02-09
ZA793743B (en) 1980-07-30
FR2432021B1 (fr) 1981-07-24

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Legal Events

Date Code Title Description
ST Notification of lapse