FR2430236A1 - Composition reductrice et procede pour la preparation de composes marques au technetium-99m, et substances radiopharmaceutiques contenant ces composes - Google Patents

Composition reductrice et procede pour la preparation de composes marques au technetium-99m, et substances radiopharmaceutiques contenant ces composes

Info

Publication number
FR2430236A1
FR2430236A1 FR7913264A FR7913264A FR2430236A1 FR 2430236 A1 FR2430236 A1 FR 2430236A1 FR 7913264 A FR7913264 A FR 7913264A FR 7913264 A FR7913264 A FR 7913264A FR 2430236 A1 FR2430236 A1 FR 2430236A1
Authority
FR
France
Prior art keywords
technetium
compounds
reducing
labeled
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7913264A
Other languages
English (en)
French (fr)
Other versions
FR2430236B1 (cg-RX-API-DMAC7.html
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Lantheus Medical Imaging Inc
Original Assignee
New England Nuclear Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by New England Nuclear Corp filed Critical New England Nuclear Corp
Publication of FR2430236A1 publication Critical patent/FR2430236A1/fr
Application granted granted Critical
Publication of FR2430236B1 publication Critical patent/FR2430236B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C01—INORGANIC CHEMISTRY
    • C01G—COMPOUNDS CONTAINING METALS NOT COVERED BY SUBCLASSES C01D OR C01F
    • C01G99/00—Subject matter not provided for in other groups of this subclass
    • C01G99/006—Compounds containing a metal not provided for elsewhere in this subclass, with or without oxygen or hydrogen, and containing two or more other elements
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/0474—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group
    • A61K51/0478—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group complexes from non-cyclic ligands, e.g. EDTA, MAG3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/12—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes, characterized by a special physical form, e.g. emulsions, dispersions, microcapsules
    • A61K51/1282—Devices used in vivo and carrying the radioactive therapeutic or diagnostic agent, therapeutic or in vivo diagnostic kits, stents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2123/00—Preparations for testing in vivo

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Optics & Photonics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Inorganic Chemistry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Dispersion Chemistry (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
FR7913264A 1978-05-25 1979-05-23 Composition reductrice et procede pour la preparation de composes marques au technetium-99m, et substances radiopharmaceutiques contenant ces composes Granted FR2430236A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/909,385 US4272503A (en) 1978-05-25 1978-05-25 Reductant composition for technetium-99m and method for making technetium-99m labelled ligands

Publications (2)

Publication Number Publication Date
FR2430236A1 true FR2430236A1 (fr) 1980-02-01
FR2430236B1 FR2430236B1 (cg-RX-API-DMAC7.html) 1983-05-13

Family

ID=25427158

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7913264A Granted FR2430236A1 (fr) 1978-05-25 1979-05-23 Composition reductrice et procede pour la preparation de composes marques au technetium-99m, et substances radiopharmaceutiques contenant ces composes

Country Status (10)

Country Link
US (1) US4272503A (cg-RX-API-DMAC7.html)
JP (2) JPS54160305A (cg-RX-API-DMAC7.html)
BE (1) BE876562A (cg-RX-API-DMAC7.html)
CA (1) CA1111765A (cg-RX-API-DMAC7.html)
CH (1) CH649924A5 (cg-RX-API-DMAC7.html)
DE (1) DE2920770A1 (cg-RX-API-DMAC7.html)
FR (1) FR2430236A1 (cg-RX-API-DMAC7.html)
GB (1) GB2023327B (cg-RX-API-DMAC7.html)
NL (1) NL7904059A (cg-RX-API-DMAC7.html)
SE (1) SE7904316L (cg-RX-API-DMAC7.html)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4421735A (en) * 1980-04-17 1983-12-20 The Massachusetts General Hospital Radiolabeled diagnostic compositions and method for making the same
US4406876A (en) * 1980-10-14 1983-09-27 Research Foundation Of The State Univ. Of New York Sulfur free small-particle production of technetium sulfur colloid
US4436718A (en) 1981-10-13 1984-03-13 Pierce Chemical Company Iodinating reagent
ES8404857A1 (es) * 1981-10-27 1984-05-16 Hybritech Inc Un procedimiento para preparar un anticuerpo monoclonal para un antigeno asociado a un tumor.
DE3237573A1 (de) * 1982-10-09 1984-04-12 Hoechst Ag, 6230 Frankfurt Technetium-99m-tri- und tetraphosphonate zur szintigraphischen dastellung res-haltiger organe und der lymphgefaesse und verfahren zu deren herstellung
US4574079A (en) * 1983-05-27 1986-03-04 Gavras Haralambos P Radiolabeled angiotensin converting enzyme inhibitors for radiolabeling mammalian organ sites
EP0163701A1 (en) * 1983-12-06 1985-12-11 The Royal Melbourne Hospital PREPARATION OF RADIOPHARMACEUTICALS BASED ON TECHNETIUM-99m/
USRE38435E1 (en) * 1983-12-28 2004-02-24 Daicel Chemical Industries, Ltd. Separating agent
US4707352A (en) * 1984-01-30 1987-11-17 Enzo Biochem, Inc. Method of radioactively labeling diagnostic and therapeutic agents containing a chelating group
US5164175A (en) * 1986-12-10 1992-11-17 Hoechst Aktiengesellschaft Diagnostic aid containing an organ-specific substance labeled with technetium-99m
US5059541A (en) * 1988-04-29 1991-10-22 Neorx Corporation Minimal derivatization of proteins
US5208007A (en) * 1988-11-22 1993-05-04 Board Of Regents Of The University Of Oklahoma Isotopic tracer composition and method for making and using same
US5808091A (en) * 1991-10-29 1998-09-15 Bracco International B.V. Rhenium and technetium complexes containing a hypoxia localizing moiety
MXPA94002323A (es) * 1993-03-31 2002-06-18 Mallinckrodt Medical Inc Formulaciones radiofarmaceuticas que tienen reductores no estanosos.
US5608110A (en) * 1993-06-15 1997-03-04 Bracco International B.V. Heteroatom-bearing ligands and metal complexes thereof
ATE334704T1 (de) * 1993-11-16 2006-08-15 Bracco Int Bv Immobilisiertes markierungsverfahren
US5774782A (en) * 1996-05-22 1998-06-30 Lockheed Martin Energy Systems, Inc. Technetium-99m generator system
WO2002082051A2 (en) * 2001-01-17 2002-10-17 Tubbs Kemmons A An integrated high throughput system for the analysis of biomolecules
US7799526B2 (en) * 2002-11-21 2010-09-21 The University Of North Carolina At Chapel Hill Phosphoprotein detection reagent and methods of making and using the same
GB0804406D0 (en) * 2008-03-10 2008-04-16 Univ Zuerich Metal complexes
JP5829919B2 (ja) * 2010-02-05 2015-12-09 ナミックス株式会社 金属導電性ペースト用の還元剤組成物

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2127809A1 (en) * 1971-06-01 1972-12-14 Kort, Waiter, Dr , 1000 Berlin Radioactive technetium-iron complex - for scintigraphy of organs and blood vessels
US3725295A (en) * 1971-07-20 1973-04-03 Atomic Energy Commission Technetium labeling
DE2419310A1 (de) * 1973-04-23 1974-11-07 Minnesota Mining & Mfg Technetium-markierte komplexe, verfahren zu deren herstellung und deren anwendung
DE2166643A1 (de) * 1971-03-25 1975-01-30 Minnesota Mining & Mfg Verfahren zum radioaktiven kennzeichnen von pharmazeutisch unbedenklichen mikropartikeln
FR2322586A1 (fr) * 1975-09-02 1977-04-01 Research Corp Nouveaux chelates radiopharmaceutiques et procede de formation d'une image externe
DE2543351A1 (de) * 1975-09-29 1977-04-07 Henkel & Cie Gmbh Praeparate zur herstellung von 99m technetum-radiodiagnostika

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3784453A (en) * 1970-12-16 1974-01-08 H Dworkin Process and apparatus for making radioactive labeled protein material
US3873680A (en) * 1972-08-30 1975-03-25 Minnesota Mining & Mfg Mercaptan and thioketal complexes of technetium 99M for diagnostic scanning

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2166643A1 (de) * 1971-03-25 1975-01-30 Minnesota Mining & Mfg Verfahren zum radioaktiven kennzeichnen von pharmazeutisch unbedenklichen mikropartikeln
DE2127809A1 (en) * 1971-06-01 1972-12-14 Kort, Waiter, Dr , 1000 Berlin Radioactive technetium-iron complex - for scintigraphy of organs and blood vessels
US3725295A (en) * 1971-07-20 1973-04-03 Atomic Energy Commission Technetium labeling
DE2419310A1 (de) * 1973-04-23 1974-11-07 Minnesota Mining & Mfg Technetium-markierte komplexe, verfahren zu deren herstellung und deren anwendung
FR2322586A1 (fr) * 1975-09-02 1977-04-01 Research Corp Nouveaux chelates radiopharmaceutiques et procede de formation d'une image externe
DE2543351A1 (de) * 1975-09-29 1977-04-07 Henkel & Cie Gmbh Praeparate zur herstellung von 99m technetum-radiodiagnostika

Also Published As

Publication number Publication date
US4272503A (en) 1981-06-09
GB2023327B (en) 1982-08-25
GB2023327A (en) 1979-12-28
JPS58146514A (ja) 1983-09-01
SE7904316L (sv) 1979-11-26
JPS54160305A (en) 1979-12-19
DE2920770A1 (de) 1979-11-29
CA1111765A (en) 1981-11-03
FR2430236B1 (cg-RX-API-DMAC7.html) 1983-05-13
NL7904059A (nl) 1979-11-27
CH649924A5 (de) 1985-06-28
BE876562A (fr) 1979-11-26

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Legal Events

Date Code Title Description
TP Transmission of property
TP Transmission of property
ST Notification of lapse