FR2424279A1 - Sels de composes de 3-cephem a faible solubilite dans l'eau utiles comme medicaments - Google Patents

Sels de composes de 3-cephem a faible solubilite dans l'eau utiles comme medicaments

Info

Publication number
FR2424279A1
FR2424279A1 FR7910053A FR7910053A FR2424279A1 FR 2424279 A1 FR2424279 A1 FR 2424279A1 FR 7910053 A FR7910053 A FR 7910053A FR 7910053 A FR7910053 A FR 7910053A FR 2424279 A1 FR2424279 A1 FR 2424279A1
Authority
FR
France
Prior art keywords
medicinal products
salts
water solubility
low water
group
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7910053A
Other languages
English (en)
Other versions
FR2424279B1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Antibioticos SA
Original Assignee
Antibioticos SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Antibioticos SA filed Critical Antibioticos SA
Publication of FR2424279A1 publication Critical patent/FR2424279A1/fr
Application granted granted Critical
Publication of FR2424279B1 publication Critical patent/FR2424279B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

L'INVENTION CONCERNE DES COMPOSES CHIMIQUES NOUVEAUX. IL S'AGIT DE COMPOSES DE FORMULE: (CF DESSIN DANS BOPI) OU R REPRESENTE UN GROUPE ACYLE; R EST UN HYDROGENE OU UN GROUPE ALCOYLE OU ALCOXY; R EST UN HYDROGENE OU UN GROUPE COMME UN ALCOYLE, UN HYDROXY, UN ALCOXY, UN ACYLOXY, UN ALCOYLTHIO OU UN GROUPE HETEROCYCLOTHIO SUBSTITUE OU NON SUBSTITUE; R ET R REPRESENTENT DES GROUPES ALCOYLE, CYCLOALCOYLE, ARYLE OU ARALCOYLE, SEMBLABLES OU DIFFERENTS: R REPRESENTE UN PONT ALCOYLENIQUE AYANT DE 1 A 10ATOMES DE CARBONE; N REPRESENTE UN NOMBRE EGAL A 1 OU 2 ET M VAUT 0 OU 1. CES COMPOSES SONT UTILES COMME MEDICAMENTS.
FR7910053A 1978-04-24 1979-04-20 Sels de composes de 3-cephem a faible solubilite dans l'eau utiles comme medicaments Granted FR2424279A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES469096A ES469096A1 (es) 1978-04-24 1978-04-24 Un procedimiento para la preparacion dos sustancialmente insolubles en agua.

Publications (2)

Publication Number Publication Date
FR2424279A1 true FR2424279A1 (fr) 1979-11-23
FR2424279B1 FR2424279B1 (fr) 1983-02-04

Family

ID=8475913

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7910053A Granted FR2424279A1 (fr) 1978-04-24 1979-04-20 Sels de composes de 3-cephem a faible solubilite dans l'eau utiles comme medicaments

Country Status (6)

Country Link
JP (1) JPS54154783A (fr)
DE (1) DE2914191A1 (fr)
ES (1) ES469096A1 (fr)
FR (1) FR2424279A1 (fr)
GB (1) GB2019838A (fr)
IT (1) IT1166759B (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1987003876A1 (fr) * 1985-12-23 1987-07-02 Beecham Group P.L.C. Cephalothine de benzathine, procede de preparation et compositions la contenant

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH059107Y2 (fr) * 1989-09-14 1993-03-05
CZ20014167A3 (cs) 1999-06-02 2002-06-12 Janssen Pharmaceutica N. V. Pyrrolidinylem, piperidinylem nebo homopiperidinylem substituované deriváty benzodioxanu, benzofuranu nebo benzopyranu

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3830809A (en) * 1972-08-25 1974-08-20 Bristol Myers Co Bis-dicyclohexylamine n-carbisobutoxycephalosporin c
ES425601A1 (es) * 1974-04-23 1976-06-16 Lafarquim Procedimiento para la obtencion de sales insolubles o poco solubles de cefalexina.

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1987003876A1 (fr) * 1985-12-23 1987-07-02 Beecham Group P.L.C. Cephalothine de benzathine, procede de preparation et compositions la contenant

Also Published As

Publication number Publication date
JPS54154783A (en) 1979-12-06
ES469096A1 (es) 1978-11-16
FR2424279B1 (fr) 1983-02-04
IT1166759B (it) 1987-05-06
GB2019838A (en) 1979-11-07
IT7922063A0 (it) 1979-04-23
DE2914191A1 (de) 1979-10-31

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