FR2421382A1 - Procede et dispositif de separation et de reaction pour analyse immunologique - Google Patents

Procede et dispositif de separation et de reaction pour analyse immunologique

Info

Publication number
FR2421382A1
FR2421382A1 FR7908016A FR7908016A FR2421382A1 FR 2421382 A1 FR2421382 A1 FR 2421382A1 FR 7908016 A FR7908016 A FR 7908016A FR 7908016 A FR7908016 A FR 7908016A FR 2421382 A1 FR2421382 A1 FR 2421382A1
Authority
FR
France
Prior art keywords
separation
reaction method
reaction
immunological analysis
filtration
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
FR7908016A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Union Carbide Corp
Original Assignee
Union Carbide Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Union Carbide Corp filed Critical Union Carbide Corp
Publication of FR2421382A1 publication Critical patent/FR2421382A1/fr
Pending legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
    • B04B—CENTRIFUGES
    • B04B5/00—Other centrifuges
    • B04B5/04—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers
    • B04B5/0407—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers for liquids contained in receptacles
    • B04B5/0414—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers for liquids contained in receptacles comprising test tubes
    • B04B5/0421—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers for liquids contained in receptacles comprising test tubes pivotably mounted
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
    • G01N33/537—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with separation of immune complex from unbound antigen or antibody
    • G01N33/538—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with separation of immune complex from unbound antigen or antibody by sorbent column, particles or resin strip, i.e. sorbent materials
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/975—Kit
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/804—Radioisotope, e.g. radioimmunoassay
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/807—Apparatus included in process claim, e.g. physical support structures
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/815—Test for named compound or class of compounds
    • Y10S436/817—Steroids or hormones
    • Y10S436/818—Human chorionic gonadotropin

Abstract

L'invention concerne un dispositif de réaction et de séparation pour analyse immunologique. Elle se rapporte à un dispositif comprenant un corps cylindrique 10 ayant une partie effilée 12 et une partie supérieure large 14. Un dispositif de filtration et de retenue est placé dans la colonne et est perméable aux solutions aqueuses uniquement lorsqu'elles sont soumises à une force centrifuge importante. Une chambre de réaction et de séparation placée au-dessus du dispositif de filtration comprend une matière assurant l'immobilisation et la séparation d'au moins un constituant d'un système antigène-anticorps. Application aux analyses radioimmunologiques des constituants du sang.
FR7908016A 1978-03-31 1979-03-30 Procede et dispositif de separation et de reaction pour analyse immunologique Pending FR2421382A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/892,321 US4244694A (en) 1978-03-31 1978-03-31 Reactor/separator device for use in automated solid phase immunoassay

Publications (1)

Publication Number Publication Date
FR2421382A1 true FR2421382A1 (fr) 1979-10-26

Family

ID=25399781

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7908016A Pending FR2421382A1 (fr) 1978-03-31 1979-03-30 Procede et dispositif de separation et de reaction pour analyse immunologique

Country Status (9)

Country Link
US (1) US4244694A (fr)
JP (1) JPS5918663B2 (fr)
AU (1) AU529435B2 (fr)
CA (1) CA1134172A (fr)
CH (1) CH631016A5 (fr)
DE (1) DE2912173C2 (fr)
FR (1) FR2421382A1 (fr)
GB (1) GB2017910B (fr)
SE (1) SE7902859L (fr)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0027986A1 (fr) * 1979-10-26 1981-05-06 Jean Guigan Dispositif d'analyses simultanées
FR2483078A1 (fr) * 1980-05-23 1981-11-27 Guigan Jean Dispositif d'analyse simultanee perfectionne notamment pour liquide biologique
EP0054262A1 (fr) * 1980-12-15 1982-06-23 Jean Guigan Dispositif autonome d'analyse simultanée et procédé de mise en oeuvre

Families Citing this family (64)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2468909A1 (fr) * 1979-10-26 1981-05-08 Guigan Jean Dispositif d'analyse simultanee
JPS56147070A (en) * 1980-04-17 1981-11-14 Olympus Optical Co Ltd Reaction container for discrete type automatic biochemical analyzer
CA1152353A (fr) * 1980-05-05 1983-08-23 Georges Revillet Rotor multicuvette pour analyseur
US4663296A (en) * 1980-05-05 1987-05-05 Hoffmann-La Roche Inc. Multicuvette rotor for analyzer
DE3169176D1 (de) * 1980-09-15 1985-04-11 Shandon Southern Prod Cytocentrifuge
DE3044385A1 (de) * 1980-11-25 1982-06-24 Boehringer Mannheim Gmbh, 6800 Mannheim Verfahren zur durchfuehrung analytischer bestimmungen und hierfuer geeignetes rotoreinsatzelement
US4425438A (en) 1981-03-13 1984-01-10 Bauman David S Assay method and device
SE8102316L (sv) * 1981-04-10 1982-10-11 Pharmacia Diagnostics Ab Anordning for genomforande av analyser
US4442218A (en) * 1981-05-27 1984-04-10 Corning Glass Works Method of measuring degree of partitioning
JPS5836631A (ja) * 1981-08-27 1983-03-03 Mochida Pharmaceut Co Ltd 固相と液相との反応方法及び装置
EP0073593A1 (fr) * 1981-09-01 1983-03-09 E.I. Du Pont De Nemours And Company Immuno-essai hétérogène utilisant le tamisage moléculaire
US4486315A (en) * 1982-03-11 1984-12-04 Ortho Diagnostic Systems Inc. Immunoassay microparticle washing system and method of use
JPS58225354A (ja) * 1982-06-24 1983-12-27 Olympus Optical Co Ltd 免疫分析法
JPS6081B2 (ja) * 1982-07-26 1985-01-05 サヌキ工業株式会社 自動抽出装置
JPS5919857A (ja) * 1982-07-26 1984-02-01 Sanuki Kogyo Kk 微量サンプルの反応方法
AU2169483A (en) * 1983-01-03 1984-07-05 Warner-Lambert Company Solid phase immunoassay
US4865997A (en) * 1984-02-23 1989-09-12 Becton Dickinson And Company Assay for ligands by separating bound and free tracer from sample
US4871683A (en) * 1985-04-18 1989-10-03 Beckman Instruments, Inc. Apparatus and method using a new reaction capsule
FR2603990B1 (fr) * 1986-09-15 1988-12-16 Plastimarne Dispositif de detection d'analyse d'identification et de caracterisation par filtration et immunofiltration
JPH087215B2 (ja) * 1987-08-24 1996-01-29 シュティフツング・フュア・ディアグノスティッシュ・フォルシュンク 抗原および／又は抗体の検出方法および検出用の試験キット
US5338689A (en) * 1987-08-24 1994-08-16 Stiftung Fur Diagnostische Forschung Method and card for detecting antigens and/or antibodies
DE8800301U1 (fr) * 1988-01-13 1988-03-03 Diekmann, Stephan, Dr., 3400 Goettingen, De
DE3843610A1 (de) * 1988-01-13 1989-07-27 Stephan Dr Diekmann Trenn- oder reaktionssaeuleneinheit
US5258309A (en) * 1988-07-25 1993-11-02 Cirrus Diagnostics, Inc. Procedure for automated solid-phase immunoassay using a centrifuge tube
US5098845A (en) * 1988-07-25 1992-03-24 Cirrus Diagnostics, Inc. Device and procedure for automated solid-phase immunoassay
JPH02151769A (ja) * 1988-12-02 1990-06-11 Jeol Ltd 反応容器
US5976389A (en) * 1988-12-30 1999-11-02 Zavos; Panayiotis M. Method of semen filtration
JP2883347B2 (ja) * 1989-03-15 1999-04-19 日本電子株式会社 自動免疫測定装置のカートリッジ洗浄装置
US5164090A (en) * 1989-11-06 1992-11-17 E. R. Squibb & Sons, Inc. Process for the direct chromatographic analysis of drugs and metabolites in whole blood samples using internal surface reverse phase technology
EP0558473A1 (fr) * 1989-11-08 1993-09-08 Fmc Corporation Tube centrifuge combine et moyen de selection poreux pour la separation et la recuperation de matieres biologiques
AU635008B2 (en) * 1989-12-13 1993-03-11 Genelabs Diagnostics Pte Ltd Analytical apparatus and method for automated blot assay
US5403745A (en) * 1990-04-27 1995-04-04 Genzyme Corporation Determination of analytes in biological fluids in the presence of substances interfering with assays therefor
US5783400A (en) * 1990-04-27 1998-07-21 Genzyme Corporation Method for the isolation of lipoprotein allowing for the subsequent quantification of its mass and cholesterol content
US5998220A (en) * 1991-05-29 1999-12-07 Beckman Coulter, Inc. Opposable-element assay devices, kits, and methods employing them
US6168956B1 (en) 1991-05-29 2001-01-02 Beckman Coulter, Inc. Multiple component chromatographic assay device
US5877028A (en) * 1991-05-29 1999-03-02 Smithkline Diagnostics, Inc. Immunochromatographic assay device
US5725832A (en) * 1992-03-25 1998-03-10 Gundelsheimer; Peter Laboratory test tubes for the dosing of liquids
US5552064A (en) * 1993-02-26 1996-09-03 Ortho Diagnostic Systems, Inc. Column agglutination assay and device using biphasic centrifugation
US5594808A (en) * 1993-06-11 1997-01-14 Ortho Diagnostic Systems Inc. Method and system for classifying agglutination reactions
US5578269A (en) * 1993-06-11 1996-11-26 Ortho Diagnostic Systems Inc. Automated blood analysis system with an integral centrifuge
US5665558A (en) * 1994-05-17 1997-09-09 Gamma Biologicals, Inc. Method and apparatus useful for detecting bloodgroup antigens and antibodies
US5905028A (en) * 1994-05-17 1999-05-18 Gamma Biologicals, Inc. Method and apparatus useful for detecting bloodgroup antigens and antibodies
US6121054A (en) * 1997-11-19 2000-09-19 Trega Biosciences, Inc. Method for separation of liquid and solid phases for solid phase organic syntheses
US6846460B1 (en) * 1999-01-29 2005-01-25 Illumina, Inc. Apparatus and method for separation of liquid phases of different density and for fluorous phase organic syntheses
GB9909630D0 (en) 1999-04-28 1999-06-23 Zeneca Ltd Reactor
US7390459B2 (en) * 1999-12-13 2008-06-24 Illumina, Inc. Oligonucleotide synthesizer
ATE527053T1 (de) 1999-12-13 2011-10-15 Illumina Inc Syntheseeinrichtung für oligonukleotide unter nutzung von fliehkraft
US20020057996A1 (en) * 2000-04-10 2002-05-16 Bass Leland L. Centrifuge tube assembly
US6401552B1 (en) * 2000-04-17 2002-06-11 Carlos D. Elkins Centrifuge tube and method for collecting and dispensing mixed concentrated fluid samples
WO2002016043A1 (fr) * 2000-08-18 2002-02-28 Arkray, Inc. Separateur centrifuge et analyseur comprenant ce dernier
WO2004004886A2 (fr) * 2002-07-05 2004-01-15 Aventis Pharmaceuticals Inc. Dispositif et procede servant a effectuer une synthese chimique en phase solide
GB0225631D0 (en) * 2002-07-05 2002-12-11 Aventis Pharma Inc Apparatus and method for use in solid phase chemical synthesis
DE102004006470B4 (de) * 2004-02-06 2006-06-01 Senova Gesellschaft für Biowissenschaft und Technik mbH Absorptionsphotometrisches Verfahren zur quantitativen Stoffanalyse
WO2007033176A2 (fr) * 2005-09-14 2007-03-22 Illumina, Inc. Dispositif de synthese en continu de polymere
US7651869B2 (en) * 2006-03-14 2010-01-26 Research International, Inc. Optical assay apparatus and methods
JP2008268194A (ja) * 2007-03-27 2008-11-06 Toray Ind Inc 分析方法
EP2367632B1 (fr) * 2008-12-23 2020-05-13 Symbion Medical Systems Sàrl Dispositif, système d'analyse et procédé pour réaliser des dosages d'agglutination
EP2403624A4 (fr) * 2009-03-02 2012-08-22 Dignity Health Dispositifs diagnostiques et procédés d'utilisation
ES2748332T3 (es) * 2010-03-30 2020-03-16 Symbion Medical Systems Sarl Estación de análisis con sistema de incubación
WO2012007503A1 (fr) * 2010-07-14 2012-01-19 Qiagen Gmbh Nouveau dispositif de stockage, de collecte ou d'isolement
CN107202727B (zh) * 2010-07-14 2020-12-22 恰根有限公司 用于分离和/或纯化生物分子的装置
GB201109203D0 (en) 2011-06-01 2011-07-13 Carclo Technical Plastics Ltd Fluid flow control
DE102011050836A1 (de) * 2011-06-03 2012-12-06 Andreas Hettich Gmbh & Co. Kg Zentrifugenrotor für ein schwenkbares Gehänge und Verfahren zur Herstellung
CN104822357B (zh) * 2012-09-18 2018-04-03 珠海丽珠圣美医疗诊断技术有限公司 旋转洗脱管

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1006557B (it) * 1971-09-08 1976-10-20 Bagshawe Kenneth Dawson Cella di reazione particolarmente utile in prove di radioimmunita
NL7112927A (fr) * 1971-09-21 1973-03-23
US3896217A (en) * 1973-03-19 1975-07-22 Summa Corp Method and apparatus for radioimmunoassay with regeneration of immunoadsorbent
IL42105A (en) * 1973-04-25 1976-08-31 Yissum Res Dev Co Process for determination of triiodothyronine
CA1054050A (fr) * 1973-05-01 1979-05-08 Stuart J. Updike Colonne de gel utilisee dans la purification de sang et les dosages immunologiques
US4039652A (en) * 1973-10-11 1977-08-02 Miles Laboratories, Inc. Column method of immunoassay employing an immobilized binding partner
US3953172A (en) * 1974-05-10 1976-04-27 Union Carbide Corporation Method and apparatus for assaying liquid materials
US4151254A (en) * 1975-06-16 1979-04-24 Union Carbide Corporation Adsorption columns for use in radioimmunoassays
US4128628A (en) * 1976-03-12 1978-12-05 University Of Virginia Alumni Patents Foundation Automated immunoassay
US4170454A (en) * 1978-03-30 1979-10-09 Union Carbide Corporation Process for the preparation of a solid-phase radioimmunoassay support and use thereof

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0027986A1 (fr) * 1979-10-26 1981-05-06 Jean Guigan Dispositif d'analyses simultanées
FR2483078A1 (fr) * 1980-05-23 1981-11-27 Guigan Jean Dispositif d'analyse simultanee perfectionne notamment pour liquide biologique
EP0054262A1 (fr) * 1980-12-15 1982-06-23 Jean Guigan Dispositif autonome d'analyse simultanée et procédé de mise en oeuvre

Also Published As

Publication number Publication date
AU4564479A (en) 1979-10-04
DE2912173A1 (de) 1979-10-04
US4244694A (en) 1981-01-13
CH631016A5 (fr) 1982-07-15
JPS5918663B2 (ja) 1984-04-28
JPS54154397A (en) 1979-12-05
GB2017910A (en) 1979-10-10
DE2912173C2 (de) 1983-05-05
SE7902859L (sv) 1979-10-01
GB2017910B (en) 1982-10-13
AU529435B2 (en) 1983-06-09
CA1134172A (fr) 1982-10-26

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