FR2410649A1 - 1-phenyl-2-pyrrolidin-2-yl-ethanols substitues, leur procede de preparation, leurs applications et medicaments les contenant - Google Patents
1-phenyl-2-pyrrolidin-2-yl-ethanols substitues, leur procede de preparation, leurs applications et medicaments les contenantInfo
- Publication number
- FR2410649A1 FR2410649A1 FR7833931A FR7833931A FR2410649A1 FR 2410649 A1 FR2410649 A1 FR 2410649A1 FR 7833931 A FR7833931 A FR 7833931A FR 7833931 A FR7833931 A FR 7833931A FR 2410649 A1 FR2410649 A1 FR 2410649A1
- Authority
- FR
- France
- Prior art keywords
- pyrrolidin
- phenyl
- ethanols
- substitutes
- applications
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/08—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D207/20—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Pain & Pain Management (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyrrole Compounds (AREA)
Abstract
1-PHENYL-PYRROLIDIN-2-YL-ETHANOLS SUBSTITUES, LEUR PROCEDE DE PREPARATION, LEURS APPLICATIONS ET MEDICAMENTS LES CONTENANT. CES 1-PHENYL-2-PYRROLIDIN-2-YL-ETHANOLS SUBSTITUES REPONDENT A LA FORMULE GENERALE I CI-DESSOUS OU R, R ET R SONT TELS QUE DEFINIS DANS LE BREVET. LE PROCEDE CONSISTE A REDUIRE UNE 1-PHENYL-2-PYRROLIDIN-2-YL-ETHANONE SUBSTITUEE OU UN DE SES SELS D'ADDITION AVEC UN ACIDE DE FORMULE GENERALE II OU III OU R, R ET R SONT TELS QUE DEFINIS DANS LE BREVET, APRES QUOI L'ON ESTERIFIE OU ETHERIFIE LE CAS ECHEANT LE COMPOSE OBTENU ETOU L'ON TRANSFORME LE CAS ECHEANT LA BASE LIBRE OBTENUE OU LE SEL D'ADDITION AVEC UN ACIDE OBTENU, L'UN DANS L'AUTRE. APPLICATION EN TANT QU'ANALGESIQUES. (CF DESSIN DANS BOPI) (CF DESSIN DANS BOPI) (CF DESSIN DANS BOPI)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
LU78625A LU78625A1 (de) | 1977-12-02 | 1977-12-02 | Substituierte 1-phenyl-2-pyrrolidin-2-yl-ethanole,verfahren zu ihrer herstellung,ihre verwendung und sie enthaltende arzneimittel |
Publications (1)
Publication Number | Publication Date |
---|---|
FR2410649A1 true FR2410649A1 (fr) | 1979-06-29 |
Family
ID=19728788
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR7833931A Pending FR2410649A1 (fr) | 1977-12-02 | 1978-12-01 | 1-phenyl-2-pyrrolidin-2-yl-ethanols substitues, leur procede de preparation, leurs applications et medicaments les contenant |
Country Status (24)
Country | Link |
---|---|
US (1) | US4198424A (fr) |
EP (1) | EP0002672B1 (fr) |
JP (1) | JPS5490172A (fr) |
AT (1) | AT372944B (fr) |
AU (1) | AU518404B2 (fr) |
BE (1) | BE872484A (fr) |
CA (1) | CA1106382A (fr) |
DE (2) | DE2860991D1 (fr) |
DK (1) | DK547978A (fr) |
ES (1) | ES475643A1 (fr) |
FR (1) | FR2410649A1 (fr) |
GB (1) | GB2011885B (fr) |
GR (1) | GR64036B (fr) |
HU (1) | HU177798B (fr) |
IE (1) | IE47604B1 (fr) |
IL (1) | IL56100A (fr) |
IT (1) | IT7830458A0 (fr) |
LU (1) | LU78625A1 (fr) |
NL (1) | NL7811786A (fr) |
NZ (1) | NZ189070A (fr) |
PL (1) | PL116668B1 (fr) |
PT (1) | PT68856A (fr) |
SE (1) | SE7812404L (fr) |
ZA (1) | ZA786749B (fr) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0022408A1 (fr) * | 1979-07-06 | 1981-01-14 | Roussel-Uclaf | Nouveaux dérivés de l'alpha-phényl 2-pyrrolidineméthanol et leurs sels, procédé de préparation, application à titre de médicaments et compositions les renfermant |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2436779A1 (fr) * | 1978-09-22 | 1980-04-18 | Pharmindustrie | Derives de pyrrolidine-2 methanol utilisables comme medicaments |
US4379161A (en) * | 1979-06-07 | 1983-04-05 | Michel Thominet | Novel substituted heterocyclic phenoxyamines, the method of preparation thereof and the use thereof as local anaesthetics |
FR2479218A2 (fr) * | 1980-04-01 | 1981-10-02 | Ile De France | Nouvelles phenoxyamines heterocycliques substituees, leur methode de preparation et leur application comme anesthesiques locaux |
FR2460935A1 (fr) * | 1979-07-06 | 1981-01-30 | Ile De France | Nouvelles phenoxyamines heterocycliques substituees, leur methode de preparation et leur application comme anesthetiques locaux |
EP0114758B1 (fr) * | 1983-01-24 | 1986-11-12 | Syntex (U.S.A.) Inc. | +/- 2-((3,4-Méthylènedioxy)phénéthyl)-5-((3-carboxamido-4-hydroxy-alpha-hydroxybenzyl)-pyrrolidines, compositions pharmaceutiques les contenant, procédé de préparation et composés intermédiaires |
NO840241L (no) * | 1983-01-24 | 1984-07-25 | Syntex Inc | Fremgangsmaate for fremstilling av terapeutisk aktive 2-((fenetyl)-5-((3,4-metylendioksy)-alfa-hydroksylbenzyl)pyrrolidiner |
ITRE940021A1 (it) * | 1994-03-29 | 1995-09-29 | Cgm Spa | Dispositivo perfezionato porta-ago per penetrazione nel corpo, quale ago per infusioni, prelievi e usi simili. |
US7403118B2 (en) * | 2005-11-29 | 2008-07-22 | Checkpoint Systems, Inc. | Security device with perimeter alarm |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4077982A (en) * | 1968-01-19 | 1978-03-07 | Fmc Corporation | 5-Benzyloxy-1,3-dioxanes |
GB1186481A (en) * | 1968-03-25 | 1970-04-02 | Parke Davis & Co | New Pyrrolidine Compounds and Methods for their Production |
GB1186660A (en) * | 1968-09-11 | 1970-04-02 | Parke Davis & Co | New Pyrrolidine Compounds and Methods for their Production |
GB1198973A (en) * | 1969-02-07 | 1970-07-15 | Parke Davis & Co | Pyrrolidine Compounds with an Unsaturated Substituent and Methods for their Production |
GB1283452A (en) * | 1970-07-24 | 1972-07-26 | Parke Davis & Co | Substituted 1,3-dialkylpyrrolidines and processes for their production |
DE2701705A1 (de) * | 1976-01-28 | 1977-08-04 | Sandoz Ag | Neue organische verbindungen, ihre verwendung und herstellung |
US4123545A (en) * | 1977-06-30 | 1978-10-31 | Sandoz Ltd. | N-Propyl-3(β-hydroxyethyl)-3-(meta-hydroxyphenyl)-pyrrolidine |
-
1977
- 1977-12-02 LU LU78625A patent/LU78625A1/de unknown
-
1978
- 1978-11-30 PT PT68856A patent/PT68856A/pt unknown
- 1978-11-30 US US05/965,147 patent/US4198424A/en not_active Expired - Lifetime
- 1978-12-01 IT IT7830458A patent/IT7830458A0/it unknown
- 1978-12-01 NZ NZ189070A patent/NZ189070A/xx unknown
- 1978-12-01 CA CA317,245A patent/CA1106382A/fr not_active Expired
- 1978-12-01 SE SE7812404A patent/SE7812404L/xx unknown
- 1978-12-01 AU AU42122/78A patent/AU518404B2/en not_active Expired
- 1978-12-01 IE IE2386/78A patent/IE47604B1/en unknown
- 1978-12-01 EP EP78101509A patent/EP0002672B1/fr not_active Expired
- 1978-12-01 PL PL1978211409A patent/PL116668B1/pl unknown
- 1978-12-01 ES ES475643A patent/ES475643A1/es not_active Expired
- 1978-12-01 GB GB7846845A patent/GB2011885B/en not_active Expired
- 1978-12-01 ZA ZA00786749A patent/ZA786749B/xx unknown
- 1978-12-01 DK DK547978A patent/DK547978A/da not_active Application Discontinuation
- 1978-12-01 GR GR57788A patent/GR64036B/el unknown
- 1978-12-01 JP JP14798878A patent/JPS5490172A/ja active Pending
- 1978-12-01 IL IL56100A patent/IL56100A/xx unknown
- 1978-12-01 BE BE6046682A patent/BE872484A/fr unknown
- 1978-12-01 DE DE7878101509T patent/DE2860991D1/de not_active Expired
- 1978-12-01 HU HU78BI580A patent/HU177798B/hu unknown
- 1978-12-01 AT AT0860278A patent/AT372944B/de not_active IP Right Cessation
- 1978-12-01 FR FR7833931A patent/FR2410649A1/fr active Pending
- 1978-12-01 DE DE19782852088 patent/DE2852088A1/de not_active Withdrawn
- 1978-12-01 NL NL7811786A patent/NL7811786A/xx not_active Application Discontinuation
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0022408A1 (fr) * | 1979-07-06 | 1981-01-14 | Roussel-Uclaf | Nouveaux dérivés de l'alpha-phényl 2-pyrrolidineméthanol et leurs sels, procédé de préparation, application à titre de médicaments et compositions les renfermant |
FR2460929A1 (fr) * | 1979-07-06 | 1981-01-30 | Roussel Uclaf | Nouveaux derives de l'a-phenyl 2-pyrrolidinemethanol et leur sels, procede de preparation, application a titre de medicaments et compositions les renfermant |
Also Published As
Publication number | Publication date |
---|---|
JPS5490172A (en) | 1979-07-17 |
IT7830458A0 (it) | 1978-12-01 |
IL56100A0 (en) | 1979-03-12 |
US4198424A (en) | 1980-04-15 |
ZA786749B (en) | 1979-11-28 |
PL211409A1 (pl) | 1979-08-13 |
HU177798B (en) | 1981-12-28 |
IE782386L (en) | 1979-06-02 |
EP0002672A3 (en) | 1979-07-25 |
SE7812404L (sv) | 1979-06-03 |
IE47604B1 (en) | 1984-05-02 |
LU78625A1 (de) | 1979-06-13 |
AU518404B2 (en) | 1981-10-01 |
BE872484A (fr) | 1979-06-01 |
AU4212278A (en) | 1979-06-07 |
DE2860991D1 (en) | 1981-11-19 |
GB2011885B (en) | 1982-06-30 |
GR64036B (en) | 1980-01-19 |
DK547978A (da) | 1979-06-03 |
PT68856A (de) | 1978-12-01 |
ATA860278A (de) | 1983-01-15 |
EP0002672B1 (fr) | 1981-08-26 |
EP0002672A2 (fr) | 1979-07-11 |
CA1106382A (fr) | 1981-08-04 |
IL56100A (en) | 1981-12-31 |
ES475643A1 (es) | 1980-01-16 |
AT372944B (de) | 1983-11-25 |
NZ189070A (en) | 1981-05-01 |
NL7811786A (nl) | 1979-06-06 |
GB2011885A (en) | 1979-07-18 |
PL116668B1 (en) | 1981-06-30 |
DE2852088A1 (de) | 1979-06-13 |
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