FR2393000A1 - Nouveaux derives acyles d'acides 3-cephem-4-carboxyliques utiles comme medicaments - Google Patents

Nouveaux derives acyles d'acides 3-cephem-4-carboxyliques utiles comme medicaments

Info

Publication number
FR2393000A1
FR2393000A1 FR7816468A FR7816468A FR2393000A1 FR 2393000 A1 FR2393000 A1 FR 2393000A1 FR 7816468 A FR7816468 A FR 7816468A FR 7816468 A FR7816468 A FR 7816468A FR 2393000 A1 FR2393000 A1 FR 2393000A1
Authority
FR
France
Prior art keywords
cephem
carboxylic acids
acyl derivatives
medicinal products
acids useful
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7816468A
Other languages
English (en)
Other versions
FR2393000B1 (fr
Inventor
Marc Montavon
Roland Reiner
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of FR2393000A1 publication Critical patent/FR2393000A1/fr
Application granted granted Critical
Publication of FR2393000B1 publication Critical patent/FR2393000B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/36—Methylene radicals, substituted by sulfur atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)

Abstract

La présente invention concerne des composés chimiques nouveaux. Il s'agit des dérivés acylés de formule générale :
FR7816468A 1977-06-03 1978-06-01 Nouveaux derives acyles d'acides 3-cephem-4-carboxyliques utiles comme medicaments Granted FR2393000A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
LU77485 1977-06-03
CH314278 1978-03-22

Publications (2)

Publication Number Publication Date
FR2393000A1 true FR2393000A1 (fr) 1978-12-29
FR2393000B1 FR2393000B1 (fr) 1982-10-29

Family

ID=25692293

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7816468A Granted FR2393000A1 (fr) 1977-06-03 1978-06-01 Nouveaux derives acyles d'acides 3-cephem-4-carboxyliques utiles comme medicaments

Country Status (26)

Country Link
EP (1) EP0000005B1 (fr)
JP (1) JPS5412394A (fr)
AR (1) AR225134A1 (fr)
AT (2) AT362501B (fr)
AU (1) AU518648B2 (fr)
BR (1) BR7803565A (fr)
CA (1) CA1114808A (fr)
CU (1) CU21118A (fr)
DE (2) DE2824065A1 (fr)
DK (1) DK246878A (fr)
ES (2) ES470442A1 (fr)
FI (1) FI781754A (fr)
FR (1) FR2393000A1 (fr)
GB (1) GB1599232A (fr)
GR (1) GR73554B (fr)
HU (1) HU182498B (fr)
IE (1) IE46903B1 (fr)
IL (1) IL54803A (fr)
IT (1) IT1098306B (fr)
MC (1) MC1195A1 (fr)
NL (1) NL7805715A (fr)
NO (1) NO781934L (fr)
NZ (1) NZ187392A (fr)
PH (1) PH14653A (fr)
PT (1) PT68134A (fr)
SE (1) SE7806465L (fr)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4200745A (en) * 1977-12-20 1980-04-29 Eli Lilly And Company 7[2-(2-Aminothiazol-4-yl)-2-alkoxyimino]acetamido 3[4-alkyl-5-oxo-6-hydroxy-3,4 dihydro 1,2,4-triazin 3-yl]thio methyl cephalosporins
FR2432521A1 (fr) * 1978-03-31 1980-02-29 Roussel Uclaf Nouvelles oximes o-substituees derivees de l'acide 7-amino thiazolyl acetamido cephalosporanique, leur procede de preparation et leur application comme medicaments
MC1259A1 (fr) * 1978-05-30 1980-01-14 Hoffmann La Roche Derives acyles
FI782683A (fi) * 1978-07-19 1980-01-20 Hoffmann La Roche Kefalosporinestrar och -estrar
US4472574A (en) * 1981-05-22 1984-09-18 Hoffman-La Roche Inc. Process for the manufacture of a cephem carboxylic acid derivative
US4698338A (en) * 1986-02-19 1987-10-06 Eli Lilly And Company 7[2-(2-aminothiazol-4-yl)-2-benzyloximino]acetamido-3[4-alkyl-5-oxo-6-hydroxy-3,4-dihydro-1,2,4-triazin-3-yl]thiomethyl cephalosporins

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1399086A (en) * 1971-05-14 1975-06-25 Glaxo Lab Ltd Cephalosporin compounds
CH609989A5 (en) * 1974-06-21 1979-03-30 Hoffmann La Roche Process for the preparation of acyl derivatives
CA1100129A (fr) * 1974-08-02 1981-04-28 William H.W. Lunn Traduction non-disponible
GB1555471A (en) * 1975-06-19 1979-11-14 Glaxo Lab Ltd 7 carbamoylalkoxyimino acetamido 3 em 4 carboxylic acidsand derivatives thereof
GB1576625A (en) * 1976-04-12 1980-10-08 Fujisawa Pharmaceutical Co Syn isomer 3,7 disubstituted 3 cephem 4 carboxylic acid compounds and processes for the preparation thereof
GB1596278A (en) * 1976-11-30 1981-08-26 Glaxo Operations Ltd 7-(-oxyimino-acetamino)cephalosporin derivatives

Also Published As

Publication number Publication date
FR2393000B1 (fr) 1982-10-29
AT365197B (de) 1981-12-28
PH14653A (en) 1981-10-14
AU3658878A (en) 1979-12-06
EP0000005B1 (fr) 1980-10-29
DE2824065A1 (de) 1978-12-14
IE46903B1 (en) 1983-11-02
IT1098306B (it) 1985-09-07
HU182498B (en) 1984-01-30
PT68134A (en) 1978-07-01
MC1195A1 (fr) 1979-02-23
IL54803A0 (en) 1978-07-31
AU518648B2 (en) 1981-10-15
NO781934L (no) 1978-12-05
NZ187392A (en) 1984-05-31
CA1114808A (fr) 1981-12-22
CU21118A (es) 1983-04-06
AT362501B (de) 1981-05-25
ES478115A1 (es) 1979-06-01
GB1599232A (en) 1981-09-30
FI781754A (fi) 1978-12-04
ATA345980A (de) 1981-05-15
BR7803565A (pt) 1979-02-20
SE7806465L (sv) 1978-12-04
IT7824165A0 (it) 1978-06-02
GR73554B (fr) 1984-03-14
JPS5412394A (en) 1979-01-30
DK246878A (da) 1978-12-04
EP0000005A1 (fr) 1978-12-20
AR225134A1 (es) 1982-02-26
DE2860248D1 (en) 1981-01-29
ES470442A1 (es) 1979-10-01
IE781056L (en) 1978-12-03
ATA403578A (de) 1980-10-15
IL54803A (en) 1982-01-31
NL7805715A (nl) 1978-12-05

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Legal Events

Date Code Title Description
ST Notification of lapse