IE781056L - Cephalosporin derivatives. - Google Patents
Cephalosporin derivatives.Info
- Publication number
- IE781056L IE781056L IE781056A IE105678A IE781056L IE 781056 L IE781056 L IE 781056L IE 781056 A IE781056 A IE 781056A IE 105678 A IE105678 A IE 105678A IE 781056 L IE781056 L IE 781056L
- Authority
- IE
- Ireland
- Prior art keywords
- see diagramm
- lower alkyl
- cephalosporin derivatives
- salts
- diagramm
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D501/14—Compounds having a nitrogen atom directly attached in position 7
- C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
- C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
- C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
- C07D501/36—Methylene radicals, substituted by sulfur atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Cephalosporin Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
Abstract
1. Cephalosporin derivatives of the general formula see diagramm : EP0000005,P15,F1 wherein R represents furyl, thienyl or phenyl optionally substituted by halogen, hydroxy, lower alkoxy or lower alkyl, R1 represents lower alkyl or aminocarbonylmethyl and X represents a group of the formulae see diagramm : EP0000005,P15,F2 see diagramm : EP0000005,P15,F3 see diagramm : EP0000005,P15,F4 in which one of the two symbols R2 and R3 or R4 and R5 represents hydrogen and the other represents lower alkyl, carboxymethyl or sulphomethyl, as well as salts of said compounds and hydrates of said salts.
[EP0000005A1]
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| LU77485 | 1977-06-03 | ||
| CH314278 | 1978-03-22 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IE781056L true IE781056L (en) | 1978-12-03 |
| IE46903B1 IE46903B1 (en) | 1983-11-02 |
Family
ID=25692293
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IE1056/78A IE46903B1 (en) | 1977-06-03 | 1978-05-26 | Novel cephalosporin derivatives, a process for their manufacture and pharmaceutical preparations |
Country Status (26)
| Country | Link |
|---|---|
| EP (1) | EP0000005B1 (en) |
| JP (1) | JPS5412394A (en) |
| AR (1) | AR225134A1 (en) |
| AT (2) | AT362501B (en) |
| AU (1) | AU518648B2 (en) |
| BR (1) | BR7803565A (en) |
| CA (1) | CA1114808A (en) |
| CU (1) | CU21118A (en) |
| DE (2) | DE2824065A1 (en) |
| DK (1) | DK246878A (en) |
| ES (2) | ES470442A1 (en) |
| FI (1) | FI781754A (en) |
| FR (1) | FR2393000A1 (en) |
| GB (1) | GB1599232A (en) |
| GR (1) | GR73554B (en) |
| HU (1) | HU182498B (en) |
| IE (1) | IE46903B1 (en) |
| IL (1) | IL54803A (en) |
| IT (1) | IT1098306B (en) |
| MC (1) | MC1195A1 (en) |
| NL (1) | NL7805715A (en) |
| NO (1) | NO781934L (en) |
| NZ (1) | NZ187392A (en) |
| PH (1) | PH14653A (en) |
| PT (1) | PT68134A (en) |
| SE (1) | SE7806465L (en) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4200745A (en) * | 1977-12-20 | 1980-04-29 | Eli Lilly And Company | 7[2-(2-Aminothiazol-4-yl)-2-alkoxyimino]acetamido 3[4-alkyl-5-oxo-6-hydroxy-3,4 dihydro 1,2,4-triazin 3-yl]thio methyl cephalosporins |
| FR2432521A1 (en) * | 1978-03-31 | 1980-02-29 | Roussel Uclaf | NOVEL O-SUBSTITUTED OXIMES DERIVED FROM 7-AMINO THIAZOLYL ACETAMIDO CEPHALOSPORANIC ACID, THEIR PREPARATION PROCESS AND THEIR USE AS MEDICAMENTS |
| MC1259A1 (en) * | 1978-05-30 | 1980-01-14 | Hoffmann La Roche | ACYL DERIVATIVES |
| FI782683A (en) * | 1978-07-19 | 1980-01-20 | Hoffmann La Roche | KEFALOSPORINESTRAR OCH -ESTRAR |
| US4472574A (en) * | 1981-05-22 | 1984-09-18 | Hoffman-La Roche Inc. | Process for the manufacture of a cephem carboxylic acid derivative |
| US4698338A (en) * | 1986-02-19 | 1987-10-06 | Eli Lilly And Company | 7[2-(2-aminothiazol-4-yl)-2-benzyloximino]acetamido-3[4-alkyl-5-oxo-6-hydroxy-3,4-dihydro-1,2,4-triazin-3-yl]thiomethyl cephalosporins |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1399086A (en) * | 1971-05-14 | 1975-06-25 | Glaxo Lab Ltd | Cephalosporin compounds |
| CH609989A5 (en) * | 1974-06-21 | 1979-03-30 | Hoffmann La Roche | Process for the preparation of acyl derivatives |
| CA1100129A (en) * | 1974-08-02 | 1981-04-28 | William H.W. Lunn | Cephalosporin compounds |
| GB1555471A (en) * | 1975-06-19 | 1979-11-14 | Glaxo Lab Ltd | 7 carbamoylalkoxyimino acetamido 3 em 4 carboxylic acidsand derivatives thereof |
| GB1576625A (en) * | 1976-04-12 | 1980-10-08 | Fujisawa Pharmaceutical Co | Syn isomer 3,7 disubstituted 3 cephem 4 carboxylic acid compounds and processes for the preparation thereof |
| GB1596278A (en) * | 1976-11-30 | 1981-08-26 | Glaxo Operations Ltd | 7-(-oxyimino-acetamino)cephalosporin derivatives |
-
1978
- 1978-05-25 NL NL7805715A patent/NL7805715A/en not_active Application Discontinuation
- 1978-05-25 GB GB22499/78A patent/GB1599232A/en not_active Expired
- 1978-05-26 NZ NZ187392A patent/NZ187392A/en unknown
- 1978-05-26 MC MC781305A patent/MC1195A1/en unknown
- 1978-05-26 IE IE1056/78A patent/IE46903B1/en unknown
- 1978-05-29 AU AU36588/78A patent/AU518648B2/en not_active Expired
- 1978-05-29 IL IL54803A patent/IL54803A/en unknown
- 1978-05-31 HU HU78HO2077A patent/HU182498B/en unknown
- 1978-06-01 SE SE7806465A patent/SE7806465L/en unknown
- 1978-06-01 DE DE19782824065 patent/DE2824065A1/en not_active Withdrawn
- 1978-06-01 GR GR56409A patent/GR73554B/el unknown
- 1978-06-01 FI FI781754A patent/FI781754A/en not_active Application Discontinuation
- 1978-06-01 DE DE7878100078T patent/DE2860248D1/en not_active Expired
- 1978-06-01 JP JP6501078A patent/JPS5412394A/en active Pending
- 1978-06-01 EP EP78100078A patent/EP0000005B1/en not_active Expired
- 1978-06-01 FR FR7816468A patent/FR2393000A1/en active Granted
- 1978-06-02 IT IT24165/78A patent/IT1098306B/en active
- 1978-06-02 DK DK246878A patent/DK246878A/en not_active Application Discontinuation
- 1978-06-02 BR BR787803565A patent/BR7803565A/en unknown
- 1978-06-02 AT AT403578A patent/AT362501B/en not_active IP Right Cessation
- 1978-06-02 ES ES470442A patent/ES470442A1/en not_active Expired
- 1978-06-02 NO NO781934A patent/NO781934L/en unknown
- 1978-06-02 AR AR272437A patent/AR225134A1/en active
- 1978-06-02 PH PH21225A patent/PH14653A/en unknown
- 1978-06-02 PT PT68134A patent/PT68134A/en unknown
- 1978-06-02 CA CA304,644A patent/CA1114808A/en not_active Expired
- 1978-07-03 CU CU7834929A patent/CU21118A/en unknown
-
1979
- 1979-02-27 ES ES478115A patent/ES478115A1/en not_active Expired
-
1980
- 1980-07-02 AT AT0345980A patent/AT365197B/en not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| FR2393000B1 (en) | 1982-10-29 |
| AT365197B (en) | 1981-12-28 |
| PH14653A (en) | 1981-10-14 |
| AU3658878A (en) | 1979-12-06 |
| EP0000005B1 (en) | 1980-10-29 |
| DE2824065A1 (en) | 1978-12-14 |
| IE46903B1 (en) | 1983-11-02 |
| IT1098306B (en) | 1985-09-07 |
| HU182498B (en) | 1984-01-30 |
| PT68134A (en) | 1978-07-01 |
| MC1195A1 (en) | 1979-02-23 |
| IL54803A0 (en) | 1978-07-31 |
| AU518648B2 (en) | 1981-10-15 |
| NO781934L (en) | 1978-12-05 |
| NZ187392A (en) | 1984-05-31 |
| CA1114808A (en) | 1981-12-22 |
| CU21118A (en) | 1983-04-06 |
| AT362501B (en) | 1981-05-25 |
| ES478115A1 (en) | 1979-06-01 |
| GB1599232A (en) | 1981-09-30 |
| FI781754A (en) | 1978-12-04 |
| ATA345980A (en) | 1981-05-15 |
| BR7803565A (en) | 1979-02-20 |
| FR2393000A1 (en) | 1978-12-29 |
| SE7806465L (en) | 1978-12-04 |
| IT7824165A0 (en) | 1978-06-02 |
| GR73554B (en) | 1984-03-14 |
| JPS5412394A (en) | 1979-01-30 |
| DK246878A (en) | 1978-12-04 |
| EP0000005A1 (en) | 1978-12-20 |
| AR225134A1 (en) | 1982-02-26 |
| DE2860248D1 (en) | 1981-01-29 |
| ES470442A1 (en) | 1979-10-01 |
| ATA403578A (en) | 1980-10-15 |
| IL54803A (en) | 1982-01-31 |
| NL7805715A (en) | 1978-12-05 |
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