ES470442A1 - New cephalosporin derivatives, their preparations and their pharmaceutical compositions. - Google Patents

New cephalosporin derivatives, their preparations and their pharmaceutical compositions.

Info

Publication number
ES470442A1
ES470442A1 ES470442A ES470442A ES470442A1 ES 470442 A1 ES470442 A1 ES 470442A1 ES 470442 A ES470442 A ES 470442A ES 470442 A ES470442 A ES 470442A ES 470442 A1 ES470442 A1 ES 470442A1
Authority
ES
Spain
Prior art keywords
preparations
cephalosporin derivatives
pharmaceutical compositions
see diagramm
lower alkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES470442A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of ES470442A1 publication Critical patent/ES470442A1/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D501/00Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/207-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/247-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/36Methylene radicals, substituted by sulfur atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)

Abstract

1. Cephalosporin derivatives of the general formula see diagramm : EP0000005,P15,F1 wherein R represents furyl, thienyl or phenyl optionally substituted by halogen, hydroxy, lower alkoxy or lower alkyl, R1 represents lower alkyl or aminocarbonylmethyl and X represents a group of the formulae see diagramm : EP0000005,P15,F2 see diagramm : EP0000005,P15,F3 see diagramm : EP0000005,P15,F4 in which one of the two symbols R2 and R3 or R4 and R5 represents hydrogen and the other represents lower alkyl, carboxymethyl or sulphomethyl, as well as salts of said compounds and hydrates of said salts.
ES470442A 1977-06-03 1978-06-02 New cephalosporin derivatives, their preparations and their pharmaceutical compositions. Expired ES470442A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
LU77485 1977-06-03
CH314278 1978-03-22

Publications (1)

Publication Number Publication Date
ES470442A1 true ES470442A1 (en) 1979-10-01

Family

ID=25692293

Family Applications (2)

Application Number Title Priority Date Filing Date
ES470442A Expired ES470442A1 (en) 1977-06-03 1978-06-02 New cephalosporin derivatives, their preparations and their pharmaceutical compositions.
ES478115A Expired ES478115A1 (en) 1977-06-03 1979-02-27 New cephalosporin derivatives, their preparations and their pharmaceutical compositions.

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES478115A Expired ES478115A1 (en) 1977-06-03 1979-02-27 New cephalosporin derivatives, their preparations and their pharmaceutical compositions.

Country Status (26)

Country Link
EP (1) EP0000005B1 (en)
JP (1) JPS5412394A (en)
AR (1) AR225134A1 (en)
AT (2) AT362501B (en)
AU (1) AU518648B2 (en)
BR (1) BR7803565A (en)
CA (1) CA1114808A (en)
CU (1) CU21118A (en)
DE (2) DE2824065A1 (en)
DK (1) DK246878A (en)
ES (2) ES470442A1 (en)
FI (1) FI781754A (en)
FR (1) FR2393000A1 (en)
GB (1) GB1599232A (en)
GR (1) GR73554B (en)
HU (1) HU182498B (en)
IE (1) IE46903B1 (en)
IL (1) IL54803A (en)
IT (1) IT1098306B (en)
MC (1) MC1195A1 (en)
NL (1) NL7805715A (en)
NO (1) NO781934L (en)
NZ (1) NZ187392A (en)
PH (1) PH14653A (en)
PT (1) PT68134A (en)
SE (1) SE7806465L (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4200745A (en) * 1977-12-20 1980-04-29 Eli Lilly And Company 7[2-(2-Aminothiazol-4-yl)-2-alkoxyimino]acetamido 3[4-alkyl-5-oxo-6-hydroxy-3,4 dihydro 1,2,4-triazin 3-yl]thio methyl cephalosporins
FR2432521A1 (en) * 1978-03-31 1980-02-29 Roussel Uclaf NOVEL O-SUBSTITUTED OXIMES DERIVED FROM 7-AMINO THIAZOLYL ACETAMIDO CEPHALOSPORANIC ACID, THEIR PREPARATION PROCESS AND THEIR USE AS MEDICAMENTS
MC1259A1 (en) * 1978-05-30 1980-01-14 Hoffmann La Roche ACYL DERIVATIVES
NO782998L (en) * 1978-07-19 1980-01-22 Hoffmann La Roche CEPHALOSPORINESTERS AND EATERS.
US4472574A (en) * 1981-05-22 1984-09-18 Hoffman-La Roche Inc. Process for the manufacture of a cephem carboxylic acid derivative
US4698338A (en) * 1986-02-19 1987-10-06 Eli Lilly And Company 7[2-(2-aminothiazol-4-yl)-2-benzyloximino]acetamido-3[4-alkyl-5-oxo-6-hydroxy-3,4-dihydro-1,2,4-triazin-3-yl]thiomethyl cephalosporins

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1399086A (en) * 1971-05-14 1975-06-25 Glaxo Lab Ltd Cephalosporin compounds
CH609989A5 (en) * 1974-06-21 1979-03-30 Hoffmann La Roche Process for the preparation of acyl derivatives
CA1100129A (en) * 1974-08-02 1981-04-28 William H.W. Lunn Cephalosporin compounds
GB1555471A (en) * 1975-06-19 1979-11-14 Glaxo Lab Ltd 7 carbamoylalkoxyimino acetamido 3 em 4 carboxylic acidsand derivatives thereof
GB1576625A (en) * 1976-04-12 1980-10-08 Fujisawa Pharmaceutical Co Syn isomer 3,7 disubstituted 3 cephem 4 carboxylic acid compounds and processes for the preparation thereof
GB1596278A (en) * 1976-11-30 1981-08-26 Glaxo Operations Ltd 7-(-oxyimino-acetamino)cephalosporin derivatives

Also Published As

Publication number Publication date
DE2824065A1 (en) 1978-12-14
IE46903B1 (en) 1983-11-02
NO781934L (en) 1978-12-05
EP0000005B1 (en) 1980-10-29
ATA345980A (en) 1981-05-15
AT362501B (en) 1981-05-25
CA1114808A (en) 1981-12-22
HU182498B (en) 1984-01-30
NL7805715A (en) 1978-12-05
GR73554B (en) 1984-03-14
DE2860248D1 (en) 1981-01-29
IL54803A0 (en) 1978-07-31
IE781056L (en) 1978-12-03
IL54803A (en) 1982-01-31
AU3658878A (en) 1979-12-06
IT1098306B (en) 1985-09-07
JPS5412394A (en) 1979-01-30
FR2393000A1 (en) 1978-12-29
DK246878A (en) 1978-12-04
EP0000005A1 (en) 1978-12-20
NZ187392A (en) 1984-05-31
MC1195A1 (en) 1979-02-23
FI781754A (en) 1978-12-04
PH14653A (en) 1981-10-14
AR225134A1 (en) 1982-02-26
CU21118A (en) 1983-04-06
ES478115A1 (en) 1979-06-01
AU518648B2 (en) 1981-10-15
PT68134A (en) 1978-07-01
GB1599232A (en) 1981-09-30
FR2393000B1 (en) 1982-10-29
AT365197B (en) 1981-12-28
IT7824165A0 (en) 1978-06-02
ATA403578A (en) 1980-10-15
BR7803565A (en) 1979-02-20
SE7806465L (en) 1978-12-04

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