FR2388823A1 - Procede d'obtention de phosphatidylcholines huileuses tres purifiees - Google Patents

Procede d'obtention de phosphatidylcholines huileuses tres purifiees

Info

Publication number
FR2388823A1
FR2388823A1 FR7812381A FR7812381A FR2388823A1 FR 2388823 A1 FR2388823 A1 FR 2388823A1 FR 7812381 A FR7812381 A FR 7812381A FR 7812381 A FR7812381 A FR 7812381A FR 2388823 A1 FR2388823 A1 FR 2388823A1
Authority
FR
France
Prior art keywords
phosphatidylcholines
oily
obtaining
purified oily
phosphatide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7812381A
Other languages
English (en)
Other versions
FR2388823B1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
A Natterman und Cie GmbH
Original Assignee
A Natterman und Cie GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by A Natterman und Cie GmbH filed Critical A Natterman und Cie GmbH
Publication of FR2388823A1 publication Critical patent/FR2388823A1/fr
Application granted granted Critical
Publication of FR2388823B1 publication Critical patent/FR2388823B1/fr
Granted legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/66Phosphorus compounds
    • A61K31/683Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols
    • A61K31/685Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols one of the hydroxy compounds having nitrogen atoms, e.g. phosphatidylserine, lecithin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • CCHEMISTRY; METALLURGY
    • C04CEMENTS; CONCRETE; ARTIFICIAL STONE; CERAMICS; REFRACTORIES
    • C04BLIME, MAGNESIA; SLAG; CEMENTS; COMPOSITIONS THEREOF, e.g. MORTARS, CONCRETE OR LIKE BUILDING MATERIALS; ARTIFICIAL STONE; CERAMICS; REFRACTORIES; TREATMENT OF NATURAL STONE
    • C04B35/00Shaped ceramic products characterised by their composition; Ceramics compositions; Processing powders of inorganic compounds preparatory to the manufacturing of ceramic products
    • C04B35/71Ceramic products containing macroscopic reinforcing agents
    • C04B35/78Ceramic products containing macroscopic reinforcing agents containing non-metallic materials
    • C04B35/80Fibres, filaments, whiskers, platelets, or the like
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/06Phosphorus compounds without P—C bonds
    • C07F9/08Esters of oxyacids of phosphorus
    • C07F9/09Esters of phosphoric acids
    • C07F9/10Phosphatides, e.g. lecithin
    • C07F9/103Extraction or purification by physical or chemical treatment of natural phosphatides; Preparation of compositions containing phosphatides of unknown structure

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Ceramic Engineering (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Manufacturing & Machinery (AREA)
  • Diabetes (AREA)
  • Materials Engineering (AREA)
  • Structural Engineering (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Fats And Perfumes (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

Procédé d'obtention de phosphatidylcholines huileuses très purifiées. Le procédé selon l'invention est caractérisé par le fait que l'on extrait le phosphatide brut huileux au moyen d'un alcool inférieur et que l'on traite directement par l'alumine l'extrait huileux de phosphatide ainsi obtenu. Application notamment à l'industrie des cosmétiques.
FR7812381A 1977-04-27 1978-04-26 Procede d'obtention de phosphatidylcholines huileuses tres purifiees Granted FR2388823A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2718797A DE2718797C3 (de) 1977-04-27 1977-04-27 Verfahren zur Gewinnung fließfähiger ölhaltiger gereinigter Phosphatidylcholin

Publications (2)

Publication Number Publication Date
FR2388823A1 true FR2388823A1 (fr) 1978-11-24
FR2388823B1 FR2388823B1 (fr) 1984-04-27

Family

ID=6007429

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7812381A Granted FR2388823A1 (fr) 1977-04-27 1978-04-26 Procede d'obtention de phosphatidylcholines huileuses tres purifiees

Country Status (18)

Country Link
US (1) US4235793A (fr)
JP (1) JPS5942655B2 (fr)
AT (1) AT376880B (fr)
AU (1) AU517042B2 (fr)
BE (1) BE866461A (fr)
CA (1) CA1097672A (fr)
CH (1) CH637528A5 (fr)
DE (1) DE2718797C3 (fr)
DK (1) DK148111C (fr)
ES (1) ES469227A1 (fr)
FR (1) FR2388823A1 (fr)
GB (1) GB1578109A (fr)
IE (1) IE46626B1 (fr)
IT (1) IT1094932B (fr)
MX (1) MX5683E (fr)
NL (1) NL7804391A (fr)
SE (1) SE431212B (fr)
ZA (1) ZA782373B (fr)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0042076A2 (fr) * 1980-06-13 1981-12-23 A. Nattermann & Cie. GmbH Procédé pour remplir des capsules dures avec des produits pharmaceutiques à viscosité élevée à la température ambiante et contenant des phospholipides
EP0043018A1 (fr) * 1980-06-25 1982-01-06 A. Nattermann & Cie. GmbH Procédé pour l'obtention de phosphatidyl choline débarrassée d'huile
EP0100902A2 (fr) * 1982-07-20 1984-02-22 A. Nattermann & Cie. GmbH Procédé de préparation de fractions éthanoliques de phosphatides fortement enrichies en phosphatidylcholine
FR2616353A1 (fr) * 1987-06-12 1988-12-16 Merieux Inst Procede de preparation d'extraits lipidiques a haute teneur en phospholipides a partir de materiau placentaire
WO2016090256A1 (fr) * 2014-12-05 2016-06-09 Archer Daniels Midland Company Procédés de fractionnement de phospholipides

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GR74979B (fr) * 1980-10-02 1984-07-12 Unilever Nv
DE3047011A1 (de) * 1980-12-13 1982-07-22 A. Nattermann & Cie GmbH, 5000 Köln Verfahren zur abtrennung von oel und/oder phosphatidylethanolamin aus diese enthaltenden alkoholloeslichen phosphatidylcholin-produkten
DE3047048A1 (de) 1980-12-13 1982-07-29 A. Nattermann & Cie GmbH, 5000 Köln Verfahren zur abtrennung von oel und/oder phosphatidylethanolamin aus diese enthaltenden alkoholloeslichen phosphatidylcholin-produkten
US4563354A (en) * 1983-10-26 1986-01-07 Kabivitrum Ab Oil-in-water emulsion for parenteral administration
JPS60152492A (ja) * 1984-01-20 1985-08-10 Asahi Glass Co Ltd リン酸エステルまたはチオリン酸エステルの製造法
US4714571A (en) * 1984-02-13 1987-12-22 The Liposome Company, Inc. Process for purification of phospholipids
JPS60197696A (ja) * 1984-03-19 1985-10-07 Sugiyama Sangyo Kagaku Kenkyusho ホスフアチジルコリンの精製法
WO1988003797A1 (fr) * 1986-11-28 1988-06-02 The Liposome Company, Inc. Composition a base de phospholipides
US5214171A (en) * 1988-12-08 1993-05-25 N.V. Vandemoortele International Process for fractionating phosphatide mixtures
US5453523A (en) * 1993-06-16 1995-09-26 Emulsion Technology, Inc. Process for obtaining highly purified phosphatidylcholine
US6140519A (en) * 1998-12-07 2000-10-31 Archer-Daniels-Midland Company Process for producing deoiled phosphatides
US6833149B2 (en) 1999-01-14 2004-12-21 Cargill, Incorporated Method and apparatus for processing vegetable oil miscella, method for conditioning a polymeric microfiltration membrane, membrane, and lecithin product
US6979459B1 (en) 2000-04-06 2005-12-27 Perricone Nicholas V Treatment of skin damage using polyenylphosphatidycholine
US6191121B1 (en) * 2000-04-06 2001-02-20 Nicholas V. Perricone Treatment of skin damage using polyenylphosphatidylcholine
US6932963B2 (en) 2000-06-23 2005-08-23 Nicholas V. Perricone Treatment of skin wounds using polyenylphosphatidylcholine and alkanolamines
WO2002049444A1 (fr) * 2000-12-21 2002-06-27 Unilever N.V. Composition alimentaire a teneur en lecithine de tournesol s'adaptant a la cuisson sautee
AU2004254011C1 (en) * 2003-06-27 2008-04-24 Unilever Plc Process for interesterification of a glyceride fat
CN1305881C (zh) * 2004-08-13 2007-03-21 河南工业大学 磷脂酰胆碱的制备方法
US7465717B2 (en) * 2004-09-27 2008-12-16 Soymor Process for releasing and extracting phosphatides from a phosphatide-containing matrix
CN102146094A (zh) * 2011-03-08 2011-08-10 南京工业大学 一种吸附法制备大豆卵磷脂的方法
CN104394850A (zh) 2012-02-16 2015-03-04 布莱特赛德创新有限公司 膳食和营养组合物及应用的方法
CA2888483C (fr) 2012-10-24 2021-09-21 Cargill, Incorporated Procede pour fractionner des phospholipides a partir d'un materiau contenant des phospholipides
US10561674B2 (en) 2012-12-02 2020-02-18 Lipogen Ltd. Processes for the preparation of phospholipid-enriched dairy products as neutraceuticals for the formulation of functional foods
US9353137B2 (en) * 2014-02-07 2016-05-31 Ghassem Amoabediny Method for separation and purification of phosphatidylcholine employing magnetic nanoparticles and compositions so produced
CN106632457B (zh) * 2016-11-18 2018-04-03 福建花巷营养科技股份有限公司 一种通过破乳精制高纯度蛋黄卵磷脂的方法

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1053299B (de) * 1957-07-09 1959-03-19 Nattermann A & Cie Verfahren zur Gewinnung von colaminphosphorsaeurediglyceridester-freien natuerlichen Cholinphosphorsaeure-diglyceridestern
US2945869A (en) * 1956-04-30 1960-07-19 Upjohn Co Phosphatide emulsifying agent and process of preparing same
CH361088A (de) * 1956-04-30 1962-03-31 Upjohn Co Verfahren zur Herstellung einer als Emulgator verwendbaren Sojaphosphatidfraktion

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE617508C (de) * 1932-06-22 1935-08-20 I G Farbenindustrie Akt Ges Verfahren zur Herstellung von reinem Lecithin
DE1617680C3 (de) * 1967-08-21 1974-01-31 A. Nattermann & Cie Gmbh, 5000 Koeln Verfahren zur Gewinnung von hochgereinigtem Phosphatidylcholin

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2945869A (en) * 1956-04-30 1960-07-19 Upjohn Co Phosphatide emulsifying agent and process of preparing same
CH361088A (de) * 1956-04-30 1962-03-31 Upjohn Co Verfahren zur Herstellung einer als Emulgator verwendbaren Sojaphosphatidfraktion
DE1053299B (de) * 1957-07-09 1959-03-19 Nattermann A & Cie Verfahren zur Gewinnung von colaminphosphorsaeurediglyceridester-freien natuerlichen Cholinphosphorsaeure-diglyceridestern

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0042076A2 (fr) * 1980-06-13 1981-12-23 A. Nattermann & Cie. GmbH Procédé pour remplir des capsules dures avec des produits pharmaceutiques à viscosité élevée à la température ambiante et contenant des phospholipides
EP0042076A3 (en) * 1980-06-13 1982-11-17 A. Nattermann & Cie. Gmbh Process for filling pharmaceutical products containing phospholipides and highly viscous at room temperature, into hard capsules
EP0043018A1 (fr) * 1980-06-25 1982-01-06 A. Nattermann & Cie. GmbH Procédé pour l'obtention de phosphatidyl choline débarrassée d'huile
EP0100902A2 (fr) * 1982-07-20 1984-02-22 A. Nattermann & Cie. GmbH Procédé de préparation de fractions éthanoliques de phosphatides fortement enrichies en phosphatidylcholine
EP0100902A3 (en) * 1982-07-20 1984-05-16 A. Nattermann & Cie. Gmbh Process for winning phosphatide ethanolic fractions highly enriched with phosphatidyl choline
FR2616353A1 (fr) * 1987-06-12 1988-12-16 Merieux Inst Procede de preparation d'extraits lipidiques a haute teneur en phospholipides a partir de materiau placentaire
EP0298787A1 (fr) * 1987-06-12 1989-01-11 Imedex Procédé de préparation d'extraits lipidiques à haute teneur en phospholipides à partir de matériau placentaire
WO2016090256A1 (fr) * 2014-12-05 2016-06-09 Archer Daniels Midland Company Procédés de fractionnement de phospholipides

Also Published As

Publication number Publication date
ZA782373B (en) 1979-05-30
JPS53136510A (en) 1978-11-29
DE2718797B2 (de) 1979-10-04
IE46626B1 (en) 1983-08-10
CH637528A5 (de) 1983-08-15
IT1094932B (it) 1985-08-10
ATA305778A (de) 1981-04-15
CA1097672A (fr) 1981-03-17
AU3540978A (en) 1979-11-01
FR2388823B1 (fr) 1984-04-27
DK148111C (da) 1985-08-26
AU517042B2 (en) 1981-07-02
DE2718797A1 (de) 1978-11-02
BE866461A (fr) 1978-08-14
IT7822672A0 (it) 1978-04-24
SE431212B (sv) 1984-01-23
DK161478A (da) 1978-10-28
AT376880B (de) 1985-01-10
JPS5942655B2 (ja) 1984-10-16
GB1578109A (en) 1980-10-29
NL7804391A (nl) 1978-10-31
ES469227A1 (es) 1978-11-16
SE7804325L (sv) 1978-10-28
IE780832L (en) 1978-10-27
DK148111B (da) 1985-03-11
DE2718797C3 (de) 1987-06-19
US4235793A (en) 1980-11-25
MX5683E (es) 1983-12-09

Similar Documents

Publication Publication Date Title
FR2388823A1 (fr) Procede d'obtention de phosphatidylcholines huileuses tres purifiees
IE812833L (en) Phosphatidylcholine purification.
FR2287431A1 (fr) Procede de distillation et de purification d'un melange contenant un alcool brut
ATE12451T1 (de) Verfahren zur abtrennung von oel und/oder phosphatidylethanolamin aus diese enthaltenden alkoholloeslichen phosphatidylcholin-produkten.
FR2376147A1 (fr) Prostaglandines bicycliques, utiles notamment comme anti-agglutinants des plaquettes sanguines et leur procede de preparation
DE69016567D1 (de) Prostaglandinanaloge enthaltende Lipidemulsion.
ATE12163T1 (de) Verfahren zur abtrennung von acylierten phospholipiden aus diese enthaltenden phosphatidylcholin-produkten.
MY107287A (en) A process for the removal of alcohols by distillation.
BR8801270A (pt) Processo para obtencao de 1,3-butadieno
FR2426038A1 (fr) Nouveaux derives d'isopropylbenzene et procede de leur preparation
FR2536751B1 (fr) Nouveaux derives de tricyclophosphazenes, procede pour leur preparation et leur application en tant que medicament
DE3360356D1 (en) Process for the separation of mixtures containing paraffins or paraffins having 6 to 14 c atoms and alcohol, or alcohols having 4 to 8 c atoms
FR2374281A1 (fr) Procede de purification d'un isoprene brut, applicable a la production de polyisoprene utile comme caoutchouc synthetique
FR2419288A1 (fr) Nouveaux derives du 5-fluoruracile, leur procede d'obtention et leur application en tant que medicaments
FR2422670A1 (fr) Procede pour l'obtention d'orthosilicates de tetraalkyle
FR2397409A1 (fr) Procede de purification de mercaptobenzothiazole
FR2361876A1 (fr) 2,9-dioxatricyclo(4,3,1,03,7)decanes, procede pour leur preparation ainsi que les produits intermediaires convenant a cet effet
FR2416878A1 (fr) Procede pour la preparation de verbenone, de myrtenal et de pinocarveol et leur utilisation therapeutique dans les maladies bronchopulmonaires
DE3369313D1 (en) Process for the preparation of o-nitrobenzaldehyde
FI822398A0 (fi) Foerfarande foer foerdelning av racematet s-(karboxi-metyl)-(rs)-cystein i isomerer (b)
FR2405918A1 (fr) Procede d'extraction d'esters de glycols vicinaux purifies
FR2357640A1 (fr) Procede de preparation de lanoline ou de ses derives moins allergeniques, par extraction liquide-liquide
SU591578A1 (ru) Устройство дл сбора и распределени продукции скважин по технологическим аппаратам
ATE10491T1 (de) Verfahren zur trennung des racemats s(carboxymethyl)-(rs)-cystein (a).
FR2398073A1 (fr) Derives d'acides n-pyridylaminomethylene-diphosphoniques, herbicides les contenant et procede de preparation de ces derniers

Legal Events

Date Code Title Description
ST Notification of lapse