FR2388823A1 - Procede d'obtention de phosphatidylcholines huileuses tres purifiees - Google Patents
Procede d'obtention de phosphatidylcholines huileuses tres purifieesInfo
- Publication number
- FR2388823A1 FR2388823A1 FR7812381A FR7812381A FR2388823A1 FR 2388823 A1 FR2388823 A1 FR 2388823A1 FR 7812381 A FR7812381 A FR 7812381A FR 7812381 A FR7812381 A FR 7812381A FR 2388823 A1 FR2388823 A1 FR 2388823A1
- Authority
- FR
- France
- Prior art keywords
- phosphatidylcholines
- oily
- obtaining
- purified oily
- phosphatide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- JLPULHDHAOZNQI-JLOPVYAASA-N [(2r)-3-hexadecanoyloxy-2-[(9e,12e)-octadeca-9,12-dienoyl]oxypropyl] 2-(trimethylazaniumyl)ethyl phosphate Chemical compound CCCCCCCCCCCCCCCC(=O)OC[C@H](COP([O-])(=O)OCC[N+](C)(C)C)OC(=O)CCCCCCC\C=C\C\C=C\CCCCC JLPULHDHAOZNQI-JLOPVYAASA-N 0.000 title 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 1
- PNEYBMLMFCGWSK-UHFFFAOYSA-N aluminium oxide Inorganic materials [O-2].[O-2].[O-2].[Al+3].[Al+3] PNEYBMLMFCGWSK-UHFFFAOYSA-N 0.000 abstract 1
- 239000002537 cosmetic Substances 0.000 abstract 1
- 150000008105 phosphatidylcholines Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/683—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols
- A61K31/685—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols one of the hydroxy compounds having nitrogen atoms, e.g. phosphatidylserine, lecithin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- C—CHEMISTRY; METALLURGY
- C04—CEMENTS; CONCRETE; ARTIFICIAL STONE; CERAMICS; REFRACTORIES
- C04B—LIME, MAGNESIA; SLAG; CEMENTS; COMPOSITIONS THEREOF, e.g. MORTARS, CONCRETE OR LIKE BUILDING MATERIALS; ARTIFICIAL STONE; CERAMICS; REFRACTORIES; TREATMENT OF NATURAL STONE
- C04B35/00—Shaped ceramic products characterised by their composition; Ceramics compositions; Processing powders of inorganic compounds preparatory to the manufacturing of ceramic products
- C04B35/71—Ceramic products containing macroscopic reinforcing agents
- C04B35/78—Ceramic products containing macroscopic reinforcing agents containing non-metallic materials
- C04B35/80—Fibres, filaments, whiskers, platelets, or the like
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/06—Phosphorus compounds without P—C bonds
- C07F9/08—Esters of oxyacids of phosphorus
- C07F9/09—Esters of phosphoric acids
- C07F9/10—Phosphatides, e.g. lecithin
- C07F9/103—Extraction or purification by physical or chemical treatment of natural phosphatides; Preparation of compositions containing phosphatides of unknown structure
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Ceramic Engineering (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Obesity (AREA)
- Hematology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Manufacturing & Machinery (AREA)
- Diabetes (AREA)
- Materials Engineering (AREA)
- Structural Engineering (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Fats And Perfumes (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
Procédé d'obtention de phosphatidylcholines huileuses très purifiées. Le procédé selon l'invention est caractérisé par le fait que l'on extrait le phosphatide brut huileux au moyen d'un alcool inférieur et que l'on traite directement par l'alumine l'extrait huileux de phosphatide ainsi obtenu. Application notamment à l'industrie des cosmétiques.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE2718797A DE2718797C3 (de) | 1977-04-27 | 1977-04-27 | Verfahren zur Gewinnung fließfähiger ölhaltiger gereinigter Phosphatidylcholin |
Publications (2)
Publication Number | Publication Date |
---|---|
FR2388823A1 true FR2388823A1 (fr) | 1978-11-24 |
FR2388823B1 FR2388823B1 (fr) | 1984-04-27 |
Family
ID=6007429
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR7812381A Granted FR2388823A1 (fr) | 1977-04-27 | 1978-04-26 | Procede d'obtention de phosphatidylcholines huileuses tres purifiees |
Country Status (18)
Country | Link |
---|---|
US (1) | US4235793A (fr) |
JP (1) | JPS5942655B2 (fr) |
AT (1) | AT376880B (fr) |
AU (1) | AU517042B2 (fr) |
BE (1) | BE866461A (fr) |
CA (1) | CA1097672A (fr) |
CH (1) | CH637528A5 (fr) |
DE (1) | DE2718797C3 (fr) |
DK (1) | DK148111C (fr) |
ES (1) | ES469227A1 (fr) |
FR (1) | FR2388823A1 (fr) |
GB (1) | GB1578109A (fr) |
IE (1) | IE46626B1 (fr) |
IT (1) | IT1094932B (fr) |
MX (1) | MX5683E (fr) |
NL (1) | NL7804391A (fr) |
SE (1) | SE431212B (fr) |
ZA (1) | ZA782373B (fr) |
Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0042076A2 (fr) * | 1980-06-13 | 1981-12-23 | A. Nattermann & Cie. GmbH | Procédé pour remplir des capsules dures avec des produits pharmaceutiques à viscosité élevée à la température ambiante et contenant des phospholipides |
EP0043018A1 (fr) * | 1980-06-25 | 1982-01-06 | A. Nattermann & Cie. GmbH | Procédé pour l'obtention de phosphatidyl choline débarrassée d'huile |
EP0100902A2 (fr) * | 1982-07-20 | 1984-02-22 | A. Nattermann & Cie. GmbH | Procédé de préparation de fractions éthanoliques de phosphatides fortement enrichies en phosphatidylcholine |
FR2616353A1 (fr) * | 1987-06-12 | 1988-12-16 | Merieux Inst | Procede de preparation d'extraits lipidiques a haute teneur en phospholipides a partir de materiau placentaire |
WO2016090256A1 (fr) * | 2014-12-05 | 2016-06-09 | Archer Daniels Midland Company | Procédés de fractionnement de phospholipides |
Families Citing this family (25)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GR74979B (fr) * | 1980-10-02 | 1984-07-12 | Unilever Nv | |
DE3047011A1 (de) * | 1980-12-13 | 1982-07-22 | A. Nattermann & Cie GmbH, 5000 Köln | Verfahren zur abtrennung von oel und/oder phosphatidylethanolamin aus diese enthaltenden alkoholloeslichen phosphatidylcholin-produkten |
DE3047048A1 (de) | 1980-12-13 | 1982-07-29 | A. Nattermann & Cie GmbH, 5000 Köln | Verfahren zur abtrennung von oel und/oder phosphatidylethanolamin aus diese enthaltenden alkoholloeslichen phosphatidylcholin-produkten |
US4563354A (en) * | 1983-10-26 | 1986-01-07 | Kabivitrum Ab | Oil-in-water emulsion for parenteral administration |
JPS60152492A (ja) * | 1984-01-20 | 1985-08-10 | Asahi Glass Co Ltd | リン酸エステルまたはチオリン酸エステルの製造法 |
US4714571A (en) * | 1984-02-13 | 1987-12-22 | The Liposome Company, Inc. | Process for purification of phospholipids |
JPS60197696A (ja) * | 1984-03-19 | 1985-10-07 | Sugiyama Sangyo Kagaku Kenkyusho | ホスフアチジルコリンの精製法 |
WO1988003797A1 (fr) * | 1986-11-28 | 1988-06-02 | The Liposome Company, Inc. | Composition a base de phospholipides |
US5214171A (en) * | 1988-12-08 | 1993-05-25 | N.V. Vandemoortele International | Process for fractionating phosphatide mixtures |
US5453523A (en) * | 1993-06-16 | 1995-09-26 | Emulsion Technology, Inc. | Process for obtaining highly purified phosphatidylcholine |
US6140519A (en) * | 1998-12-07 | 2000-10-31 | Archer-Daniels-Midland Company | Process for producing deoiled phosphatides |
US6833149B2 (en) | 1999-01-14 | 2004-12-21 | Cargill, Incorporated | Method and apparatus for processing vegetable oil miscella, method for conditioning a polymeric microfiltration membrane, membrane, and lecithin product |
US6979459B1 (en) | 2000-04-06 | 2005-12-27 | Perricone Nicholas V | Treatment of skin damage using polyenylphosphatidycholine |
US6191121B1 (en) * | 2000-04-06 | 2001-02-20 | Nicholas V. Perricone | Treatment of skin damage using polyenylphosphatidylcholine |
US6932963B2 (en) | 2000-06-23 | 2005-08-23 | Nicholas V. Perricone | Treatment of skin wounds using polyenylphosphatidylcholine and alkanolamines |
WO2002049444A1 (fr) * | 2000-12-21 | 2002-06-27 | Unilever N.V. | Composition alimentaire a teneur en lecithine de tournesol s'adaptant a la cuisson sautee |
AU2004254011C1 (en) * | 2003-06-27 | 2008-04-24 | Unilever Plc | Process for interesterification of a glyceride fat |
CN1305881C (zh) * | 2004-08-13 | 2007-03-21 | 河南工业大学 | 磷脂酰胆碱的制备方法 |
US7465717B2 (en) * | 2004-09-27 | 2008-12-16 | Soymor | Process for releasing and extracting phosphatides from a phosphatide-containing matrix |
CN102146094A (zh) * | 2011-03-08 | 2011-08-10 | 南京工业大学 | 一种吸附法制备大豆卵磷脂的方法 |
CN104394850A (zh) | 2012-02-16 | 2015-03-04 | 布莱特赛德创新有限公司 | 膳食和营养组合物及应用的方法 |
CA2888483C (fr) | 2012-10-24 | 2021-09-21 | Cargill, Incorporated | Procede pour fractionner des phospholipides a partir d'un materiau contenant des phospholipides |
US10561674B2 (en) | 2012-12-02 | 2020-02-18 | Lipogen Ltd. | Processes for the preparation of phospholipid-enriched dairy products as neutraceuticals for the formulation of functional foods |
US9353137B2 (en) * | 2014-02-07 | 2016-05-31 | Ghassem Amoabediny | Method for separation and purification of phosphatidylcholine employing magnetic nanoparticles and compositions so produced |
CN106632457B (zh) * | 2016-11-18 | 2018-04-03 | 福建花巷营养科技股份有限公司 | 一种通过破乳精制高纯度蛋黄卵磷脂的方法 |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE1053299B (de) * | 1957-07-09 | 1959-03-19 | Nattermann A & Cie | Verfahren zur Gewinnung von colaminphosphorsaeurediglyceridester-freien natuerlichen Cholinphosphorsaeure-diglyceridestern |
US2945869A (en) * | 1956-04-30 | 1960-07-19 | Upjohn Co | Phosphatide emulsifying agent and process of preparing same |
CH361088A (de) * | 1956-04-30 | 1962-03-31 | Upjohn Co | Verfahren zur Herstellung einer als Emulgator verwendbaren Sojaphosphatidfraktion |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE617508C (de) * | 1932-06-22 | 1935-08-20 | I G Farbenindustrie Akt Ges | Verfahren zur Herstellung von reinem Lecithin |
DE1617680C3 (de) * | 1967-08-21 | 1974-01-31 | A. Nattermann & Cie Gmbh, 5000 Koeln | Verfahren zur Gewinnung von hochgereinigtem Phosphatidylcholin |
-
1977
- 1977-04-27 DE DE2718797A patent/DE2718797C3/de not_active Expired
-
1978
- 1978-04-13 DK DK161478A patent/DK148111C/da not_active IP Right Cessation
- 1978-04-17 SE SE7804325A patent/SE431212B/sv not_active IP Right Cessation
- 1978-04-18 CA CA301,397A patent/CA1097672A/fr not_active Expired
- 1978-04-24 IT IT22672/78A patent/IT1094932B/it active
- 1978-04-24 AU AU35409/78A patent/AU517042B2/en not_active Expired
- 1978-04-24 US US05/899,525 patent/US4235793A/en not_active Expired - Lifetime
- 1978-04-25 NL NL7804391A patent/NL7804391A/xx not_active Application Discontinuation
- 1978-04-26 MX MX787042U patent/MX5683E/es unknown
- 1978-04-26 GB GB16591/78A patent/GB1578109A/en not_active Expired
- 1978-04-26 IE IE83278A patent/IE46626B1/en unknown
- 1978-04-26 ZA ZA00782373A patent/ZA782373B/xx unknown
- 1978-04-26 FR FR7812381A patent/FR2388823A1/fr active Granted
- 1978-04-27 CH CH456578A patent/CH637528A5/de not_active IP Right Cessation
- 1978-04-27 ES ES469227A patent/ES469227A1/es not_active Expired
- 1978-04-27 BE BE187179A patent/BE866461A/fr not_active IP Right Cessation
- 1978-04-27 AT AT0305778A patent/AT376880B/de not_active IP Right Cessation
- 1978-04-27 JP JP53049389A patent/JPS5942655B2/ja not_active Expired
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2945869A (en) * | 1956-04-30 | 1960-07-19 | Upjohn Co | Phosphatide emulsifying agent and process of preparing same |
CH361088A (de) * | 1956-04-30 | 1962-03-31 | Upjohn Co | Verfahren zur Herstellung einer als Emulgator verwendbaren Sojaphosphatidfraktion |
DE1053299B (de) * | 1957-07-09 | 1959-03-19 | Nattermann A & Cie | Verfahren zur Gewinnung von colaminphosphorsaeurediglyceridester-freien natuerlichen Cholinphosphorsaeure-diglyceridestern |
Cited By (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0042076A2 (fr) * | 1980-06-13 | 1981-12-23 | A. Nattermann & Cie. GmbH | Procédé pour remplir des capsules dures avec des produits pharmaceutiques à viscosité élevée à la température ambiante et contenant des phospholipides |
EP0042076A3 (en) * | 1980-06-13 | 1982-11-17 | A. Nattermann & Cie. Gmbh | Process for filling pharmaceutical products containing phospholipides and highly viscous at room temperature, into hard capsules |
EP0043018A1 (fr) * | 1980-06-25 | 1982-01-06 | A. Nattermann & Cie. GmbH | Procédé pour l'obtention de phosphatidyl choline débarrassée d'huile |
EP0100902A2 (fr) * | 1982-07-20 | 1984-02-22 | A. Nattermann & Cie. GmbH | Procédé de préparation de fractions éthanoliques de phosphatides fortement enrichies en phosphatidylcholine |
EP0100902A3 (en) * | 1982-07-20 | 1984-05-16 | A. Nattermann & Cie. Gmbh | Process for winning phosphatide ethanolic fractions highly enriched with phosphatidyl choline |
FR2616353A1 (fr) * | 1987-06-12 | 1988-12-16 | Merieux Inst | Procede de preparation d'extraits lipidiques a haute teneur en phospholipides a partir de materiau placentaire |
EP0298787A1 (fr) * | 1987-06-12 | 1989-01-11 | Imedex | Procédé de préparation d'extraits lipidiques à haute teneur en phospholipides à partir de matériau placentaire |
WO2016090256A1 (fr) * | 2014-12-05 | 2016-06-09 | Archer Daniels Midland Company | Procédés de fractionnement de phospholipides |
Also Published As
Publication number | Publication date |
---|---|
ZA782373B (en) | 1979-05-30 |
JPS53136510A (en) | 1978-11-29 |
DE2718797B2 (de) | 1979-10-04 |
IE46626B1 (en) | 1983-08-10 |
CH637528A5 (de) | 1983-08-15 |
IT1094932B (it) | 1985-08-10 |
ATA305778A (de) | 1981-04-15 |
CA1097672A (fr) | 1981-03-17 |
AU3540978A (en) | 1979-11-01 |
FR2388823B1 (fr) | 1984-04-27 |
DK148111C (da) | 1985-08-26 |
AU517042B2 (en) | 1981-07-02 |
DE2718797A1 (de) | 1978-11-02 |
BE866461A (fr) | 1978-08-14 |
IT7822672A0 (it) | 1978-04-24 |
SE431212B (sv) | 1984-01-23 |
DK161478A (da) | 1978-10-28 |
AT376880B (de) | 1985-01-10 |
JPS5942655B2 (ja) | 1984-10-16 |
GB1578109A (en) | 1980-10-29 |
NL7804391A (nl) | 1978-10-31 |
ES469227A1 (es) | 1978-11-16 |
SE7804325L (sv) | 1978-10-28 |
IE780832L (en) | 1978-10-27 |
DK148111B (da) | 1985-03-11 |
DE2718797C3 (de) | 1987-06-19 |
US4235793A (en) | 1980-11-25 |
MX5683E (es) | 1983-12-09 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
ST | Notification of lapse |