FR2384793A1 - Nouveaux 7-halo-3,20-dioxo1,4-pregnadienes et 4-pregnenes, leur procede de preparation et compositions pharmaceutiques contenant lesdits composes - Google Patents

Nouveaux 7-halo-3,20-dioxo1,4-pregnadienes et 4-pregnenes, leur procede de preparation et compositions pharmaceutiques contenant lesdits composes

Info

Publication number
FR2384793A1
FR2384793A1 FR7738297A FR7738297A FR2384793A1 FR 2384793 A1 FR2384793 A1 FR 2384793A1 FR 7738297 A FR7738297 A FR 7738297A FR 7738297 A FR7738297 A FR 7738297A FR 2384793 A1 FR2384793 A1 FR 2384793A1
Authority
FR
France
Prior art keywords
pregnadienes
pregnenes
halo
compounds
dioxo1
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7738297A
Other languages
English (en)
French (fr)
Other versions
FR2384793B1 (sv
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Scherico Ltd
Original Assignee
Scherico Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US05/753,257 external-priority patent/US4076708A/en
Application filed by Scherico Ltd filed Critical Scherico Ltd
Publication of FR2384793A1 publication Critical patent/FR2384793A1/fr
Application granted granted Critical
Publication of FR2384793B1 publication Critical patent/FR2384793B1/fr
Granted legal-status Critical Current

Links

Classifications

    • E—FIXED CONSTRUCTIONS
    • E04—BUILDING
    • E04G—SCAFFOLDING; FORMS; SHUTTERING; BUILDING IMPLEMENTS OR AIDS, OR THEIR USE; HANDLING BUILDING MATERIALS ON THE SITE; REPAIRING, BREAKING-UP OR OTHER WORK ON EXISTING BUILDINGS
    • E04G11/00—Forms, shutterings, or falsework for making walls, floors, ceilings, or roofs
    • E04G11/06—Forms, shutterings, or falsework for making walls, floors, ceilings, or roofs for walls, e.g. curved end panels for wall shutterings; filler elements for wall shutterings; shutterings for vertical ducts
    • E04G11/20—Movable forms; Movable forms for moulding cylindrical, conical or hyperbolical structures; Templates serving as forms for positioning blocks or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J21/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J21/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J21/001—Lactones
    • C07J21/003—Lactones at position 17
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C07J5/0046—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa
    • C07J5/0053—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa not substituted in position 16
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C07J5/0046—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa
    • C07J5/0061—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16
    • C07J5/0069—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group
    • C07J5/0076—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group by an alkyl group
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C07J5/0046—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa
    • C07J5/0061—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16
    • C07J5/0069—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group
    • C07J5/0084—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group by an alkylene group
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
    • C07J7/0005—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21
    • C07J7/001—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group
    • C07J7/004—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group substituted in position 17 alfa
    • C07J7/0045—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group substituted in position 17 alfa not substituted in position 16
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
    • C07J7/008—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms substituted in position 21
    • C07J7/0085—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms substituted in position 21 by an halogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0005—Oxygen-containing hetero ring
    • C07J71/0026—Oxygen-containing hetero ring cyclic ketals
    • C07J71/0031—Oxygen-containing hetero ring cyclic ketals at positions 16, 17
    • E—FIXED CONSTRUCTIONS
    • E04—BUILDING
    • E04G—SCAFFOLDING; FORMS; SHUTTERING; BUILDING IMPLEMENTS OR AIDS, OR THEIR USE; HANDLING BUILDING MATERIALS ON THE SITE; REPAIRING, BREAKING-UP OR OTHER WORK ON EXISTING BUILDINGS
    • E04G17/00—Connecting or other auxiliary members for forms, falsework structures, or shutterings
    • E04G17/14—Bracing or strutting arrangements for formwalls; Devices for aligning forms

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Architecture (AREA)
  • Engineering & Computer Science (AREA)
  • Civil Engineering (AREA)
  • Mechanical Engineering (AREA)
  • Structural Engineering (AREA)
  • Animal Behavior & Ethology (AREA)
  • Rheumatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pain & Pain Management (AREA)
  • Medicinal Chemistry (AREA)
  • Steroid Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Saccharide Compounds (AREA)
FR7738297A 1976-12-22 1977-12-19 Nouveaux 7-halo-3,20-dioxo1,4-pregnadienes et 4-pregnenes, leur procede de preparation et compositions pharmaceutiques contenant lesdits composes Granted FR2384793A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US75325676A 1976-12-22 1976-12-22
US05/753,257 US4076708A (en) 1976-12-22 1976-12-22 Process for the preparation of 7α-halogeno-3-oxo-4-dehydro steroids and novel 7α-halogeno derivatives produced thereby

Publications (2)

Publication Number Publication Date
FR2384793A1 true FR2384793A1 (fr) 1978-10-20
FR2384793B1 FR2384793B1 (sv) 1981-11-13

Family

ID=27115720

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7738297A Granted FR2384793A1 (fr) 1976-12-22 1977-12-19 Nouveaux 7-halo-3,20-dioxo1,4-pregnadienes et 4-pregnenes, leur procede de preparation et compositions pharmaceutiques contenant lesdits composes

Country Status (20)

Country Link
JP (1) JPS604198B2 (sv)
AR (1) AR226806A1 (sv)
AT (2) AT373269B (sv)
BE (1) BE862089A (sv)
DE (1) DE2756550C2 (sv)
DK (1) DK153494C (sv)
FI (1) FI63947C (sv)
FR (1) FR2384793A1 (sv)
GB (1) GB1575983A (sv)
HK (1) HK584A (sv)
HU (1) HU179784B (sv)
IE (1) IE45950B1 (sv)
IL (1) IL53636A (sv)
MY (1) MY8500082A (sv)
NL (1) NL180479C (sv)
NO (1) NO151826C (sv)
NZ (1) NZ186031A (sv)
PT (1) PT67432B (sv)
SE (1) SE429865B (sv)
SG (1) SG58683G (sv)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109680036A (zh) 2017-10-02 2019-04-26 爱科来株式会社 糖化蛋白质的测定

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3429926A (en) * 1964-05-25 1969-02-25 Squibb & Sons Inc 7-halo and 6-halo,6-dehydro a-norprogesterones

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3429926A (en) * 1964-05-25 1969-02-25 Squibb & Sons Inc 7-halo and 6-halo,6-dehydro a-norprogesterones

Also Published As

Publication number Publication date
NL180479C (nl) 1987-03-02
MY8500082A (en) 1985-12-31
IL53636A (en) 1983-05-15
FI773825A (fi) 1978-06-23
PT67432A (en) 1978-01-01
DK153494B (da) 1988-07-18
DE2756550A1 (de) 1978-07-06
JPS604198B2 (ja) 1985-02-01
SE7714538L (sv) 1978-06-23
NO151826C (no) 1985-06-12
HU179784B (en) 1982-12-28
FI63947C (fi) 1983-09-12
DE2756550C2 (de) 1986-10-16
BE862089A (fr) 1978-06-20
DK569977A (da) 1978-09-28
AR226806A1 (es) 1982-08-31
IL53636A0 (en) 1978-03-10
NO774359L (no) 1978-06-23
IE45950B1 (en) 1983-01-12
ATA575980A (de) 1982-04-15
IE45950L (en) 1978-06-22
NL180479B (nl) 1986-10-01
DK153494C (da) 1989-02-20
NL7714056A (nl) 1978-06-26
NO151826B (no) 1985-03-04
NZ186031A (en) 1984-07-31
AT377566B (de) 1985-04-10
PT67432B (en) 1979-05-23
AT373269B (de) 1984-01-10
JPS5379850A (en) 1978-07-14
SE429865B (sv) 1983-10-03
SG58683G (en) 1985-01-11
GB1575983A (en) 1980-10-01
FR2384793B1 (sv) 1981-11-13
FI63947B (fi) 1983-05-31
ATA909477A (de) 1983-05-15
HK584A (en) 1984-01-13

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Legal Events

Date Code Title Description
CD Change of name or company name
CC Supplementary protection certificate (spc) laid open to the public (law of 25 june 1990)

Free format text: 92C0099, 920424

CB Supplementary protection certificate (spc) granted (law of 25 june 1990)

Free format text: 92C0099, 771219

CL Concession to grant licences