FR2383959B1 - - Google Patents

Info

Publication number
FR2383959B1
FR2383959B1 FR7821950A FR7821950A FR2383959B1 FR 2383959 B1 FR2383959 B1 FR 2383959B1 FR 7821950 A FR7821950 A FR 7821950A FR 7821950 A FR7821950 A FR 7821950A FR 2383959 B1 FR2383959 B1 FR 2383959B1
Authority
FR
France
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
FR7821950A
Other versions
FR2383959A1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Publication of FR2383959A1 publication Critical patent/FR2383959A1/fr
Application granted granted Critical
Publication of FR2383959B1 publication Critical patent/FR2383959B1/fr
Priority claimed from AU79443/91A external-priority patent/AU645095B2/en
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D477/00—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
    • C07D477/02—Preparation
    • C07D477/04—Preparation by forming the ring or condensed ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D477/00—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
    • C07D477/10—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic System
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804—Compounds having Si-O-C linkages
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
    • C07F9/568—Four-membered rings
FR7821950A 1976-11-19 1978-07-25 Intermediaire de synthese de l'acide 1-carba-2-penem-3-carboxylique Granted FR2383959A1 (fr)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US74337076A 1976-11-19 1976-11-19
US74336376A 1976-11-19 1976-11-19
US84317177A 1977-10-19 1977-10-19
AU79443/91A AU645095B2 (en) 1976-11-19 1991-07-01 Improved process for recovering organic vapors from air

Publications (2)

Publication Number Publication Date
FR2383959A1 FR2383959A1 (fr) 1978-10-13
FR2383959B1 true FR2383959B1 (fr) 1982-04-02

Family

ID=27423898

Family Applications (3)

Application Number Title Priority Date Filing Date
FR7734768A Expired FR2371449B1 (fr) 1976-11-19 1977-11-18 Acide 1-carba-2-penem-3-carboxylique
FR7821950A Granted FR2383959A1 (fr) 1976-11-19 1978-07-25 Intermediaire de synthese de l'acide 1-carba-2-penem-3-carboxylique
FR7821951A Granted FR2383960A1 (fr) 1976-11-19 1978-07-25 Intermediaire dans la synthese de l'acide 1-carba-2-penem-3-carboxylique

Family Applications Before (1)

Application Number Title Priority Date Filing Date
FR7734768A Expired FR2371449B1 (fr) 1976-11-19 1977-11-18 Acide 1-carba-2-penem-3-carboxylique

Family Applications After (1)

Application Number Title Priority Date Filing Date
FR7821951A Granted FR2383960A1 (fr) 1976-11-19 1978-07-25 Intermediaire dans la synthese de l'acide 1-carba-2-penem-3-carboxylique

Country Status (9)

Country Link
EP (1) EP0521203A1 (fr)
JP (1) JPS6033836B2 (fr)
CH (1) CH640856A5 (fr)
DE (1) DE2751624A1 (fr)
FR (3) FR2371449B1 (fr)
GB (1) GB1593524A (fr)
LU (1) LU78538A1 (fr)
NL (1) NL7712750A (fr)
SE (1) SE436130B (fr)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2811514A1 (de) * 1977-03-19 1978-09-21 Beecham Group Ltd Ester der 7-oxo-1-azabicyclo eckige klammer auf 3.2.0 eckige klammer zu hept- 2-en-2-carbonsaeure und deren derivate, verfahren zur herstellung dieser verbindungen und diese verbindungen enthaltende pharmazeutische zubereitungen
EP0000828B1 (fr) * 1977-08-06 1983-03-09 Beecham Group Plc Composés synthétiques à noyau béta-lactame, procédé pour leur préparation et les compositions les contenant
AU531084B2 (en) * 1977-10-19 1983-08-11 Merck & Co., Inc. Azetidine derivatives
AU4061378A (en) * 1977-10-19 1980-04-17 Merck & Co., Inc. 1-azabicyclo (3.2.0) hept-2-enes
EP0003740B1 (fr) * 1978-01-19 1982-01-27 Beecham Group Plc Antibiotiques dérivés de bêta-lactame, un procédé pour leur préparation et compositions pharmaceutiques les contenant
US4272439A (en) * 1978-06-02 1981-06-09 Schering Corporation 6-(Substituted-hydroxymethylene penams)
NZ190994A (en) 1978-07-24 1981-10-19 Merck & Co Inc Z-2-acylamino-3-monosubstituted propenoates
US4446146A (en) * 1978-07-26 1984-05-01 Beecham Group Limited β-Lactam containing compounds, their preparation and use
US4260627A (en) * 1978-10-24 1981-04-07 Merck & Co., Inc. 1-, 6- And 2-substituted-1-carba-2-penem-3-carboxylic acids
DE3071008D1 (en) * 1979-04-27 1985-09-26 Merck & Co Inc Process for the preparation of 3-(1-hydroxyethyl)-azetidinones
JPS56142260A (en) * 1980-04-09 1981-11-06 Toyama Chem Co Ltd 2-azetidinone and its preparation
CA1179675A (fr) * 1981-01-30 1984-12-18 Erwin Gotschi Derives du 7-oxo-1-azabicyclo ¬3,2,0| heptene-2-
EP0059554A3 (fr) * 1981-02-27 1982-10-20 Beecham Group Plc Antibiotiques bêta-lactame, un procédé pour leur préparation et leur application en compositions pharmaceutiques
KR900006449B1 (ko) * 1982-08-24 1990-08-31 상꾜 가부시끼가이샤 아제티디논 화합물의 제조방법
US4992542A (en) * 1984-01-24 1991-02-12 Merck & Co., Inc. 2-substituted-6-carbadethiapen-2-em-3-carboxylic acids
JPS60208981A (ja) * 1984-03-15 1985-10-21 Sanraku Inc 新規カルバペナム及びカルバペネム誘導体
EP0277743A1 (fr) * 1987-02-02 1988-08-10 Merck & Co. Inc. 2-(Hétéroaryliumalkyl)phényl-carbapénèmes, comme agents antibactériens
JPS63290879A (ja) * 1988-04-05 1988-11-28 Sankyo Co Ltd ２−メチルカルバペネム誘導体
EP0466254A1 (fr) * 1990-07-11 1992-01-15 Merck & Co. Inc. 2-Naphtyle-carbapénèmes
EP0466253A1 (fr) * 1990-07-11 1992-01-15 Merck & Co. Inc. 2-Naphtyle-carbapénèmes
US5409920A (en) * 1990-10-05 1995-04-25 Merck & Co., Inc. 2-(3-pyridyl)-carbapenem antibacterial agents
GB9103034D0 (en) * 1991-02-13 1991-03-27 Fujisawa Pharmaceutical Co Processes for preparing carbapenem derivatives
US20020147333A1 (en) 1993-10-29 2002-10-10 Smithkline Beecham P.L.C. 2-(pyrazol-3-yl)carbapenem derivatives
US5606051A (en) * 1993-10-29 1997-02-25 Smithkline Beecham P.L.C. 2-(pyrazol-3-yl)carbapenem derivatives
AP9600800A0 (en) * 1993-10-29 1996-04-30 Smithkline Beecham Plc 2-(Pyrazol-3-yl) carbapenem derivatives.
EP0785937A1 (fr) * 1994-10-14 1997-07-30 Smithkline Beecham Plc Derives de 2-(imidazol-4-yl)carbapeneme, leurs intermediaires ainsi que leur utilisation en tant qu'antibacteriens
EP0823911A1 (fr) * 1995-05-03 1998-02-18 Smithkline Beecham Plc Esters de carbapenemes
IL118092A0 (en) * 1995-05-03 1996-09-12 Smithkline Beecham Plc Antibacterial compounds their preparation and pharmaceutical compositions containing them
US5814127A (en) * 1996-12-23 1998-09-29 American Air Liquide Inc. Process for recovering CF4 and C2 F6 from a gas
WO2004089954A1 (fr) * 2003-04-08 2004-10-21 Sumitomo Pharmaceuticals Co., Ltd. Nouveaux composes de carbapenem

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3950357A (en) * 1974-11-25 1976-04-13 Merck & Co., Inc. Antibiotics
DE2456307A1 (de) * 1974-11-28 1976-08-12 Bayer Ag Beta-lactam-antibiotica, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel
IL50911A (en) * 1975-11-21 1981-01-30 Merck & Co Inc Substituted n-methylene derivatives of thienamycin
DE2811514A1 (de) * 1977-03-19 1978-09-21 Beecham Group Ltd Ester der 7-oxo-1-azabicyclo eckige klammer auf 3.2.0 eckige klammer zu hept- 2-en-2-carbonsaeure und deren derivate, verfahren zur herstellung dieser verbindungen und diese verbindungen enthaltende pharmazeutische zubereitungen
US4553983A (en) * 1984-07-31 1985-11-19 Membrane Technology And Research, Inc. Process for recovering organic vapors from air
US4701187A (en) * 1986-11-03 1987-10-20 Air Products And Chemicals, Inc. Process for separating components of a gas stream
EP0343284B1 (fr) * 1988-03-25 1993-03-03 OTTO OEKO-TECH GMBH & CO. KG Procédé d'obtenir d'hydrocarbures de courants de gaz d'une haute teneur
US4906256A (en) * 1989-03-23 1990-03-06 Membrane Technology & Research, Inc. Membrane process for treatment of fluorinated hydrocarbon-laden gas streams

Also Published As

Publication number Publication date
GB1593524A (en) 1981-07-15
FR2371449B1 (fr) 1985-06-21
FR2383960B1 (fr) 1982-02-26
SE7713008L (sv) 1978-05-20
LU78538A1 (fr) 1978-07-14
JPS6033836B2 (ja) 1985-08-05
FR2383959A1 (fr) 1978-10-13
NL7712750A (nl) 1978-05-23
FR2371449A1 (fr) 1978-06-16
DE2751624A1 (de) 1978-06-01
DE2751624C2 (fr) 1988-09-08
JPS5387390A (en) 1978-08-01
EP0521203A1 (fr) 1993-01-07
CH640856A5 (en) 1984-01-31
FR2383960A1 (fr) 1978-10-13
SE436130B (sv) 1984-11-12

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Legal Events

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