FR2382461A1 - Antigene du virus de rubeole, purifie, son procede de fabrication et son application a la detection des anticorps du virus de rubeole - Google Patents

Antigene du virus de rubeole, purifie, son procede de fabrication et son application a la detection des anticorps du virus de rubeole

Info

Publication number
FR2382461A1
FR2382461A1 FR7805741A FR7805741A FR2382461A1 FR 2382461 A1 FR2382461 A1 FR 2382461A1 FR 7805741 A FR7805741 A FR 7805741A FR 7805741 A FR7805741 A FR 7805741A FR 2382461 A1 FR2382461 A1 FR 2382461A1
Authority
FR
France
Prior art keywords
rubella virus
rubella
antigen
substance
purifies
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
FR7805741A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Abbott Laboratories
Original Assignee
Abbott Laboratories
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Laboratories filed Critical Abbott Laboratories
Publication of FR2382461A1 publication Critical patent/FR2382461A1/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56983—Viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/20—Rubella virus
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/36011—Togaviridae
    • C12N2770/36211—Rubivirus, e.g. rubella virus
    • C12N2770/36234—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/36011—Togaviridae
    • C12N2770/36211—Rubivirus, e.g. rubella virus
    • C12N2770/36251—Methods of production or purification of viral material

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biotechnology (AREA)
  • Mycology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Urology & Nephrology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Cell Biology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • General Engineering & Computer Science (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

L'invention concerne un procédé pour la production d'un antigène soluble de la rubéole. Ce procédé comprend les étapes suivantes : a on soumet les milieux de croissance d'une culture de tissu de cellules infectées par le virus de la rubéole à une séparation chromatographique sur une colonne consistant en une phase solide sur laquelle on a fixé l'IgG dérivant du sérum humain connu comme contenant des anticorps réactifs vis-à-vis des antigènes de la rubéole; b. on élue ladite colonne pour séparer les substances fixées à l'IgG qu'elle contient; c. on soumet la substance éluée séparée à une chromatographie par perméation de gel pour effectuer la séparation dela substance sur la base de la taille moléculaire; d. on isole l'antigène de la rubéole de ladite substance éluée séparée classifiée sur la base de l'activté relative d'hémagglutination passive inverse.
FR7805741A 1977-03-01 1978-02-28 Antigene du virus de rubeole, purifie, son procede de fabrication et son application a la detection des anticorps du virus de rubeole Withdrawn FR2382461A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US77323177A 1977-03-01 1977-03-01

Publications (1)

Publication Number Publication Date
FR2382461A1 true FR2382461A1 (fr) 1978-09-29

Family

ID=25097600

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7805741A Withdrawn FR2382461A1 (fr) 1977-03-01 1978-02-28 Antigene du virus de rubeole, purifie, son procede de fabrication et son application a la detection des anticorps du virus de rubeole

Country Status (9)

Country Link
JP (1) JPS53107414A (fr)
AU (1) AU513684B2 (fr)
CA (1) CA1087983A (fr)
CH (1) CH639207A5 (fr)
DE (1) DE2808615A1 (fr)
FR (1) FR2382461A1 (fr)
GB (1) GB1592825A (fr)
NL (1) NL7802216A (fr)
SE (1) SE7802069L (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2514367A1 (fr) * 1981-10-08 1983-04-15 Pasteur Institut Procede pour la detection de germes pathogenes dans des fluides par filtration sur des immunoadsorbants, et application a la determination de la potabilite d'une eau

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI841094A (fi) * 1984-03-19 1985-09-20 Univ Tennesee Research Corp Virusantigen bunden vid en baerare, dess framstaellning och anvaendning.
JPS6147566A (ja) * 1984-08-13 1986-03-08 Tetsuo Tomiyama 抗風疹ウイルス抗体感作血球及びこれを用いる抗風疹ウイルス抗体の測定方法
JPS6153569A (ja) * 1984-08-24 1986-03-17 Tetsuo Tomiyama 抗風疹ウイルス抗体感作ラテツクス及びこれを用いる抗風疹ウイルス抗体の測定方法
JPH03127305U (fr) * 1990-04-04 1991-12-20
JPH0412201U (fr) * 1990-05-23 1992-01-31

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2088988A5 (en) * 1970-03-11 1972-01-07 Takeda Chemical Industries Ltd Haemagglutinating antigen prodn for german measles virus

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2088988A5 (en) * 1970-03-11 1972-01-07 Takeda Chemical Industries Ltd Haemagglutinating antigen prodn for german measles virus

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2514367A1 (fr) * 1981-10-08 1983-04-15 Pasteur Institut Procede pour la detection de germes pathogenes dans des fluides par filtration sur des immunoadsorbants, et application a la determination de la potabilite d'une eau

Also Published As

Publication number Publication date
SE7802069L (sv) 1978-09-02
DE2808615A1 (de) 1978-09-07
CH639207A5 (en) 1983-10-31
AU513684B2 (en) 1980-12-18
JPS6231301B2 (fr) 1987-07-07
AU3318178A (en) 1979-08-16
GB1592825A (en) 1981-07-08
CA1087983A (fr) 1980-10-21
JPS53107414A (en) 1978-09-19
NL7802216A (nl) 1978-09-05

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