FR2378520A1 - Derives de methoxy-2 benzamides - Google Patents
Derives de methoxy-2 benzamidesInfo
- Publication number
- FR2378520A1 FR2378520A1 FR7639034A FR7639034A FR2378520A1 FR 2378520 A1 FR2378520 A1 FR 2378520A1 FR 7639034 A FR7639034 A FR 7639034A FR 7639034 A FR7639034 A FR 7639034A FR 2378520 A1 FR2378520 A1 FR 2378520A1
- Authority
- FR
- France
- Prior art keywords
- alkyl
- benzamide
- cpds
- esp
- pyrrolidinyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 229940001470 psychoactive drug Drugs 0.000 title abstract 2
- 239000004089 psychotropic agent Substances 0.000 title abstract 2
- AJVBPNRMKNARPG-UHFFFAOYSA-N 3-sulfamoylbenzamide Chemical compound NC(=O)C1=CC=CC(S(N)(=O)=O)=C1 AJVBPNRMKNARPG-UHFFFAOYSA-N 0.000 title 1
- 230000000506 psychotropic effect Effects 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 5
- 125000003545 alkoxy group Chemical group 0.000 abstract 2
- -1 cyano, formyl Chemical group 0.000 abstract 2
- 125000001475 halogen functional group Chemical group 0.000 abstract 2
- 125000000876 trifluoromethoxy group Chemical group FC(F)(F)O* 0.000 abstract 2
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 2
- AFVFQIVMOAPDHO-UHFFFAOYSA-N Methanesulfonic acid Chemical class CS(O)(=O)=O AFVFQIVMOAPDHO-UHFFFAOYSA-N 0.000 abstract 1
- 208000019695 Migraine disease Diseases 0.000 abstract 1
- OKFHNNUPPQPSHO-UHFFFAOYSA-N N-[(1-benzylpyrrolidin-2-yl)methyl]-2-methoxybenzamide Chemical class C(C1=CC=CC=C1)N1C(CCC1)CNC(C1=C(C=CC=C1)OC)=O OKFHNNUPPQPSHO-UHFFFAOYSA-N 0.000 abstract 1
- 208000012545 Psychophysiologic disease Diseases 0.000 abstract 1
- 208000028017 Psychotic disease Diseases 0.000 abstract 1
- 208000012886 Vertigo Diseases 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 125000004453 alkoxycarbonyl group Chemical group 0.000 abstract 1
- 125000004202 aminomethyl group Chemical group [H]N([H])C([H])([H])* 0.000 abstract 1
- 125000003917 carbamoyl group Chemical group [H]N([H])C(*)=O 0.000 abstract 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
- 125000004218 chloromethyl group Chemical group [H]C([H])(Cl)* 0.000 abstract 1
- 230000003001 depressive effect Effects 0.000 abstract 1
- 208000000718 duodenal ulcer Diseases 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- CJXGPJZUDUOZDX-UHFFFAOYSA-N fluoromethanone Chemical group F[C]=O CJXGPJZUDUOZDX-UHFFFAOYSA-N 0.000 abstract 1
- 125000004029 hydroxymethyl group Chemical group [H]OC([H])([H])* 0.000 abstract 1
- 239000000543 intermediate Substances 0.000 abstract 1
- 206010027599 migraine Diseases 0.000 abstract 1
- 230000000701 neuroleptic effect Effects 0.000 abstract 1
- 230000003287 optical effect Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 231100000889 vertigo Toxicity 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C17/00—Preparation of halogenated hydrocarbons
- C07C17/093—Preparation of halogenated hydrocarbons by replacement by halogens
- C07C17/16—Preparation of halogenated hydrocarbons by replacement by halogens of hydroxyl groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/45—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by condensation
- C07C45/46—Friedel-Crafts reactions
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/08—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/24—Oxygen or sulfur atoms
- C07D207/26—2-Pyrrolidones
- C07D207/273—2-Pyrrolidones with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to other ring carbon atoms
- C07D207/277—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D207/28—2-Pyrrolidone-5- carboxylic acids; Functional derivatives thereof, e.g. esters, nitriles
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Hydrogenated Pyridines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (15)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7639034A FR2378520A1 (fr) | 1976-12-24 | 1976-12-24 | Derives de methoxy-2 benzamides |
| NO774402A NO774402L (no) | 1976-12-24 | 1977-12-21 | R fremgangsmaate for fremstilling av metoksy-benzamidderivate |
| FI773911A FI773911A7 (fi) | 1976-12-24 | 1977-12-22 | Metoxibenzamidderivat |
| DE19772757406 DE2757406A1 (de) | 1976-12-24 | 1977-12-22 | 2-methoxy-benzamidderivate, verfahren zu ihrer herstellung und sie enthaltende arzneimittel |
| GB53570/77A GB1556566A (en) | 1976-12-24 | 1977-12-22 | 2-methoxybenzamides |
| IL53680A IL53680A0 (en) | 1976-12-24 | 1977-12-22 | Novel 2-methoxybenzamide derivatives their preparation and pharmaceutical compositions containing them |
| DK575877A DK575877A (da) | 1976-12-24 | 1977-12-22 | Fremgangsmaade til fremstilling af 2-methoxybenzamider |
| SE7714659A SE7714659L (sv) | 1976-12-24 | 1977-12-22 | Metoxibensamider |
| NZ186075A NZ186075A (en) | 1976-12-24 | 1977-12-22 | 2-methoxybenzamide derivatives, and pharmaceutical compositions containing them |
| AU31921/77A AU3192177A (en) | 1976-12-24 | 1977-12-22 | 2-methoxybenzamides |
| ES465366A ES465366A2 (es) | 1976-12-24 | 1977-12-23 | Un procedimiento de preparacion de derivados de metoxi-2- benzamidas. |
| LU78773A LU78773A1 (fr) | 1976-12-24 | 1977-12-23 | Procede de preparation de methoxy-2-benzamides |
| NL7714301A NL7714301A (nl) | 1976-12-24 | 1977-12-23 | Werkwijze voor het bereiden van een geneesmiddel, zo gevormd geneesmiddel. |
| JP15630677A JPS5382771A (en) | 1976-12-24 | 1977-12-23 | Methoxybenzamide derivative |
| GR55032A GR66082B (enExample) | 1976-12-24 | 1977-12-27 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7639034A FR2378520A1 (fr) | 1976-12-24 | 1976-12-24 | Derives de methoxy-2 benzamides |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FR2378520A1 true FR2378520A1 (fr) | 1978-08-25 |
| FR2378520B1 FR2378520B1 (enExample) | 1979-05-11 |
Family
ID=9181520
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR7639034A Granted FR2378520A1 (fr) | 1976-12-24 | 1976-12-24 | Derives de methoxy-2 benzamides |
Country Status (1)
| Country | Link |
|---|---|
| FR (1) | FR2378520A1 (enExample) |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2305973A1 (fr) * | 1975-04-02 | 1976-10-29 | Yamanouchi Pharma Co Ltd | Nouveaux derives du benzamide |
-
1976
- 1976-12-24 FR FR7639034A patent/FR2378520A1/fr active Granted
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2305973A1 (fr) * | 1975-04-02 | 1976-10-29 | Yamanouchi Pharma Co Ltd | Nouveaux derives du benzamide |
Also Published As
| Publication number | Publication date |
|---|---|
| FR2378520B1 (enExample) | 1979-05-11 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ST | Notification of lapse |