FR2374901A1 - Derives actifs de methylamine, leurs procedes de preparation ainsi que les compositions therapeutiques les contenant - Google Patents

Derives actifs de methylamine, leurs procedes de preparation ainsi que les compositions therapeutiques les contenant

Info

Publication number
FR2374901A1
FR2374901A1 FR7716280A FR7716280A FR2374901A1 FR 2374901 A1 FR2374901 A1 FR 2374901A1 FR 7716280 A FR7716280 A FR 7716280A FR 7716280 A FR7716280 A FR 7716280A FR 2374901 A1 FR2374901 A1 FR 2374901A1
Authority
FR
France
Prior art keywords
methylamine
compositions containing
therapeutic compositions
preparation processes
active derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7716280A
Other languages
English (en)
Other versions
FR2374901B1 (fr
Inventor
Charles Pigerol
Pierre Eymard
Jean-Claude Vernieres
Madeleine Brol
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Labaz SA
Original Assignee
Labaz SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Labaz SA filed Critical Labaz SA
Publication of FR2374901A1 publication Critical patent/FR2374901A1/fr
Application granted granted Critical
Publication of FR2374901B1 publication Critical patent/FR2374901B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D203/00—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D203/04—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D203/06—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D203/08—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring nitrogen atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/04—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/02—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements
    • C07D295/027—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring
    • C07D295/03—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring with the ring nitrogen atoms directly attached to acyclic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/14—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D295/145—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/15—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

L'invention concerne des dérivés de méthylamine en tant que nouveaux médicaments notamment pour traiter la maladie de Parkinson et corriger les troubles extra-pyramidaux engendrés par les neuroleptiques. Les dérivés de l'invention sont ceux représentés par la formule générale :
FR7716280A 1976-06-03 1977-05-27 Derives actifs de methylamine, leurs procedes de preparation ainsi que les compositions therapeutiques les contenant Granted FR2374901A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
BE842528 1976-06-03

Publications (2)

Publication Number Publication Date
FR2374901A1 true FR2374901A1 (fr) 1978-07-21
FR2374901B1 FR2374901B1 (fr) 1981-04-17

Family

ID=3861370

Family Applications (2)

Application Number Title Priority Date Filing Date
FR7716280A Granted FR2374901A1 (fr) 1976-06-03 1977-05-27 Derives actifs de methylamine, leurs procedes de preparation ainsi que les compositions therapeutiques les contenant
FR7808094A Granted FR2372795A1 (fr) 1976-06-03 1978-03-21 Nouveaux derives de meth

Family Applications After (1)

Application Number Title Priority Date Filing Date
FR7808094A Granted FR2372795A1 (fr) 1976-06-03 1978-03-21 Nouveaux derives de meth

Country Status (17)

Country Link
JP (1) JPS6039261B2 (fr)
AR (4) AR213646A1 (fr)
AT (1) AT352088B (fr)
AU (1) AU511705B2 (fr)
DK (1) DK146063C (fr)
ES (2) ES459466A1 (fr)
FI (1) FI63015C (fr)
FR (2) FR2374901A1 (fr)
GR (1) GR61148B (fr)
MX (1) MX4778E (fr)
NL (1) NL7706052A (fr)
NO (1) NO145337C (fr)
NZ (1) NZ184161A (fr)
PT (1) PT66623B (fr)
SE (2) SE452317B (fr)
YU (1) YU129577A (fr)
ZA (1) ZA773151B (fr)

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE815273A (fr) * 1974-05-20 1974-11-20 Derives actifs de methylamine
BE842528R (fr) * 1976-06-03 1976-12-03 Derives actifs de methylamine, compositions therapeutiques les contenant ainsi que les procedes de preparation de ces derives et compositions

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE815273A (fr) * 1974-05-20 1974-11-20 Derives actifs de methylamine
BE842528R (fr) * 1976-06-03 1976-12-03 Derives actifs de methylamine, compositions therapeutiques les contenant ainsi que les procedes de preparation de ces derives et compositions

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
NV1007/72 *

Also Published As

Publication number Publication date
YU129577A (en) 1983-01-21
JPS52148006A (en) 1977-12-08
SE8206445L (sv) 1982-11-12
PT66623A (en) 1977-07-01
SE452317B (sv) 1987-11-23
AU511705B2 (en) 1980-09-04
ZA773151B (en) 1978-04-26
AR215053A1 (es) 1979-08-31
SE452763B (sv) 1987-12-14
PT66623B (en) 1978-11-07
FI63015B (fi) 1982-12-31
DK244677A (da) 1977-12-04
FI63015C (fi) 1983-04-11
DK146063C (da) 1983-11-14
MX4778E (es) 1982-09-15
NO145337C (no) 1982-03-03
AU2556177A (en) 1978-11-30
AR215175A1 (es) 1979-09-14
NO145337B (no) 1981-11-23
SE8206445D0 (sv) 1982-11-12
DK146063B (da) 1983-06-20
NZ184161A (en) 1980-10-08
FR2374901B1 (fr) 1981-04-17
AR215052A1 (es) 1979-08-31
JPS6039261B2 (ja) 1985-09-05
FR2372795A1 (fr) 1978-06-30
GR61148B (en) 1978-09-27
SE7706448L (sv) 1977-12-04
NO771941L (no) 1977-12-06
NL7706052A (nl) 1977-12-06
FR2372795B1 (fr) 1983-08-12
AR213646A1 (es) 1979-02-28
FI771780A (fr) 1977-12-04
ES459466A1 (es) 1978-08-16
ES470379A1 (es) 1979-10-16
AT352088B (de) 1979-08-27
ATA395877A (de) 1979-02-15

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Legal Events

Date Code Title Description
TP Transmission of property
CA Change of address
CD Change of name or company name
ST Notification of lapse