FR2369264A1 - 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridine-dicarboxylate d'isopropyle et d - Google Patents
1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridine-dicarboxylate d'isopropyle et dInfo
- Publication number
- FR2369264A1 FR2369264A1 FR7732558A FR7732558A FR2369264A1 FR 2369264 A1 FR2369264 A1 FR 2369264A1 FR 7732558 A FR7732558 A FR 7732558A FR 7732558 A FR7732558 A FR 7732558A FR 2369264 A1 FR2369264 A1 FR 2369264A1
- Authority
- FR
- France
- Prior art keywords
- isopropyl
- nitrophenyl
- dihydro
- pyridine
- dimethyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- -1 2-propoxyethyl Chemical group 0.000 abstract 3
- 150000001875 compounds Chemical class 0.000 abstract 3
- WFDIJRYMOXRFFG-UHFFFAOYSA-N Acetic anhydride Chemical compound CC(=O)OC(C)=O WFDIJRYMOXRFFG-UHFFFAOYSA-N 0.000 abstract 2
- 125000001449 isopropyl group Chemical group [H]C([H])([H])C([H])(*)C([H])([H])[H] 0.000 abstract 2
- 239000003814 drug Substances 0.000 abstract 1
- 230000005923 long-lasting effect Effects 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 230000002093 peripheral effect Effects 0.000 abstract 1
- 238000011321 prophylaxis Methods 0.000 abstract 1
- 238000002560 therapeutic procedure Methods 0.000 abstract 1
- 230000024883 vasodilation Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
- C07D211/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE2650013A DE2650013C3 (de) | 1976-10-30 | 1976-10-30 | 1.4-Dihydro-2.6-dimethyl-4-(3-nitrophenyl)-3.5-pyridindicarbonsäureisopropyl-(2-propoxy-äthyl)-ester, Verfahren zu seiner Herstellung sowie ihn enthaltende Arzneimittel |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FR2369264A1 true FR2369264A1 (fr) | 1978-05-26 |
| FR2369264B1 FR2369264B1 (Direct) | 1980-06-13 |
Family
ID=5992142
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR7732558A Granted FR2369264A1 (fr) | 1976-10-30 | 1977-10-28 | 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridine-dicarboxylate d'isopropyle et d |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US4166855A (Direct) |
| JP (1) | JPS5356672A (Direct) |
| AT (1) | AT357162B (Direct) |
| AU (1) | AU507892B2 (Direct) |
| BE (1) | BE860248A (Direct) |
| CA (1) | CA1070314A (Direct) |
| CH (2) | CH633265A5 (Direct) |
| DE (1) | DE2650013C3 (Direct) |
| ES (1) | ES463646A1 (Direct) |
| FI (1) | FI60705C (Direct) |
| FR (1) | FR2369264A1 (Direct) |
| GB (1) | GB1568740A (Direct) |
| NL (1) | NL7711827A (Direct) |
| SE (1) | SE433211B (Direct) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS57175164A (en) * | 1981-04-18 | 1982-10-28 | Banyu Pharmaceut Co Ltd | 1,4-dihydropyridine derivative and its preparation |
| DE3208628A1 (de) * | 1982-03-10 | 1983-09-22 | Bayer Ag, 5090 Leverkusen | Neue verbindungen, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel |
| JPS58185821U (ja) * | 1982-06-02 | 1983-12-10 | 日産自動車株式会社 | ウインドシ−ルド |
| DE3248548A1 (de) * | 1982-12-29 | 1984-07-05 | Heinrich Mack Nachf., 7918 Illertissen | Acylderivate von 1,4:3,6-dianhydro-hexiten, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel |
| DE3316510A1 (de) * | 1983-05-06 | 1984-11-08 | Bayer Ag | Parenterale formulierung von nimodipin, ein verfahren zu ihrer herstellung sowie ihre verwendung bei der bekaempfung von erkrankungen |
| JPS60214778A (ja) * | 1984-03-08 | 1985-10-28 | Suntory Ltd | Ν置換３，４−ジヒドロピリミジン誘導体ならびにその製造法および用途 |
| DE3544692A1 (de) * | 1985-12-18 | 1987-06-19 | Bayer Ag | Dihydropyridinspray, verfahren zu seiner herstellung und seine pharmazeutische verwendung |
| LV12200B (lv) * | 1997-07-03 | 1999-04-20 | Gun�rs DUBURS | Antidiabētisks līdzeklis |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2117573A1 (de) * | 1971-04-10 | 1972-10-19 | Farbenfabriken Bayer Ag, 5090 Leverkusen | Verfahren zur Herstellung von neuen unsymmetrischen 1,4-Dihydropyridindicarbonsäureestern, sowie ihre Verwendung als Arzneimittel |
| FR2132830A1 (Direct) * | 1971-04-10 | 1972-11-24 | Bayer Ag |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1670827C3 (de) * | 1967-03-20 | 1974-10-24 | Bayer Ag, 5090 Leverkusen | 4-(2'-Nitrophenyl)-2,6-dimethyl-3,5-dicarbmethoxy-1,4-dihydropyridin |
-
1976
- 1976-10-30 DE DE2650013A patent/DE2650013C3/de not_active Expired
-
1977
- 1977-10-06 US US05/840,065 patent/US4166855A/en not_active Expired - Lifetime
- 1977-10-25 GB GB44332/77A patent/GB1568740A/en not_active Expired
- 1977-10-25 CH CH1298277A patent/CH633265A5/de not_active IP Right Cessation
- 1977-10-27 FI FI773208A patent/FI60705C/fi not_active IP Right Cessation
- 1977-10-27 NL NL7711827A patent/NL7711827A/xx not_active Application Discontinuation
- 1977-10-27 SE SE7712108A patent/SE433211B/xx unknown
- 1977-10-28 AT AT773177A patent/AT357162B/de not_active IP Right Cessation
- 1977-10-28 AU AU30147/77A patent/AU507892B2/en not_active Expired
- 1977-10-28 JP JP12881477A patent/JPS5356672A/ja active Granted
- 1977-10-28 BE BE182159A patent/BE860248A/xx not_active IP Right Cessation
- 1977-10-28 ES ES463646A patent/ES463646A1/es not_active Expired
- 1977-10-28 FR FR7732558A patent/FR2369264A1/fr active Granted
- 1977-10-28 CA CA289,781A patent/CA1070314A/en not_active Expired
-
1981
- 1981-11-25 CH CH754481A patent/CH635078A5/de not_active IP Right Cessation
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2117573A1 (de) * | 1971-04-10 | 1972-10-19 | Farbenfabriken Bayer Ag, 5090 Leverkusen | Verfahren zur Herstellung von neuen unsymmetrischen 1,4-Dihydropyridindicarbonsäureestern, sowie ihre Verwendung als Arzneimittel |
| FR2132830A1 (Direct) * | 1971-04-10 | 1972-11-24 | Bayer Ag |
Also Published As
| Publication number | Publication date |
|---|---|
| NL7711827A (nl) | 1978-05-03 |
| ES463646A1 (es) | 1978-07-16 |
| SE7712108L (sv) | 1978-05-01 |
| DE2650013B2 (de) | 1980-06-12 |
| FI60705B (fi) | 1981-11-30 |
| AU507892B2 (en) | 1980-02-28 |
| JPS5356672A (en) | 1978-05-23 |
| JPS577149B2 (Direct) | 1982-02-09 |
| AU3014777A (en) | 1979-05-03 |
| CH635078A5 (de) | 1983-03-15 |
| AT357162B (de) | 1980-06-25 |
| ATA773177A (de) | 1979-11-15 |
| SE433211B (sv) | 1984-05-14 |
| CH633265A5 (de) | 1982-11-30 |
| DE2650013C3 (de) | 1981-04-02 |
| FI60705C (fi) | 1982-03-10 |
| GB1568740A (en) | 1980-06-04 |
| FI773208A7 (fi) | 1978-05-01 |
| FR2369264B1 (Direct) | 1980-06-13 |
| DE2650013A1 (de) | 1978-05-11 |
| BE860248A (fr) | 1978-04-28 |
| US4166855A (en) | 1979-09-04 |
| CA1070314A (en) | 1980-01-22 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ST | Notification of lapse |