ES463646A1 - Procedimiento para la obtencion de 1,4-dihidro-2,6-dimetil- 4-(3-nitrofenil)-3,5-piridin-dicarboxilatos de isopropil-(2-propoxietilo). - Google Patents

Procedimiento para la obtencion de 1,4-dihidro-2,6-dimetil- 4-(3-nitrofenil)-3,5-piridin-dicarboxilatos de isopropil-(2-propoxietilo).

Info

Publication number
ES463646A1
ES463646A1 ES463646A ES463646A ES463646A1 ES 463646 A1 ES463646 A1 ES 463646A1 ES 463646 A ES463646 A ES 463646A ES 463646 A ES463646 A ES 463646A ES 463646 A1 ES463646 A1 ES 463646A1
Authority
ES
Spain
Prior art keywords
nitrophenyl
dihydro
dimethyl
pyridinedicarboxylic acid
acid ester
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES463646A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer AG
Original Assignee
Bayer AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer AG filed Critical Bayer AG
Publication of ES463646A1 publication Critical patent/ES463646A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
    • C07D211/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)

Abstract

Procedimiento para la obtención de 1,4-dihidro-2,6-dimetil-4-(3-nitrofenil)-3,5-piridin-dicarboxilatos de isopropilo-(2-propoxietilo) de fórmula I ***(Ver fórmula I) caracterizado porque 3'-nitrobenzilicenacetoacetato de isopropilo de fórmula II ***(Ver fórmula II)
ES463646A 1976-10-30 1977-10-28 Procedimiento para la obtencion de 1,4-dihidro-2,6-dimetil- 4-(3-nitrofenil)-3,5-piridin-dicarboxilatos de isopropil-(2-propoxietilo). Expired ES463646A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2650013A DE2650013C3 (de) 1976-10-30 1976-10-30 1.4-Dihydro-2.6-dimethyl-4-(3-nitrophenyl)-3.5-pyridindicarbonsäureisopropyl-(2-propoxy-äthyl)-ester, Verfahren zu seiner Herstellung sowie ihn enthaltende Arzneimittel

Publications (1)

Publication Number Publication Date
ES463646A1 true ES463646A1 (es) 1978-07-16

Family

ID=5992142

Family Applications (1)

Application Number Title Priority Date Filing Date
ES463646A Expired ES463646A1 (es) 1976-10-30 1977-10-28 Procedimiento para la obtencion de 1,4-dihidro-2,6-dimetil- 4-(3-nitrofenil)-3,5-piridin-dicarboxilatos de isopropil-(2-propoxietilo).

Country Status (14)

Country Link
US (1) US4166855A (es)
JP (1) JPS5356672A (es)
AT (1) AT357162B (es)
AU (1) AU507892B2 (es)
BE (1) BE860248A (es)
CA (1) CA1070314A (es)
CH (2) CH633265A5 (es)
DE (1) DE2650013C3 (es)
ES (1) ES463646A1 (es)
FI (1) FI60705C (es)
FR (1) FR2369264A1 (es)
GB (1) GB1568740A (es)
NL (1) NL7711827A (es)
SE (1) SE433211B (es)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS57175164A (en) * 1981-04-18 1982-10-28 Banyu Pharmaceut Co Ltd 1,4-dihydropyridine derivative and its preparation
DE3208628A1 (de) * 1982-03-10 1983-09-22 Bayer Ag, 5090 Leverkusen Neue verbindungen, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel
JPS58185821U (ja) * 1982-06-02 1983-12-10 日産自動車株式会社 ウインドシ−ルド
DE3248548A1 (de) * 1982-12-29 1984-07-05 Heinrich Mack Nachf., 7918 Illertissen Acylderivate von 1,4:3,6-dianhydro-hexiten, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
DE3316510A1 (de) * 1983-05-06 1984-11-08 Bayer Ag Parenterale formulierung von nimodipin, ein verfahren zu ihrer herstellung sowie ihre verwendung bei der bekaempfung von erkrankungen
JPS60214778A (ja) * 1984-03-08 1985-10-28 Suntory Ltd Ν置換３，４−ジヒドロピリミジン誘導体ならびにその製造法および用途
DE3544692A1 (de) * 1985-12-18 1987-06-19 Bayer Ag Dihydropyridinspray, verfahren zu seiner herstellung und seine pharmazeutische verwendung
LV12200B (lv) * 1997-07-03 1999-04-20 Gunārs DUBURS Antidiabētisks līdzeklis

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1670827C3 (de) * 1967-03-20 1974-10-24 Bayer Ag, 5090 Leverkusen 4-(2'-Nitrophenyl)-2,6-dimethyl-3,5-dicarbmethoxy-1,4-dihydropyridin
DE2117571C3 (de) * 1971-04-10 1979-10-11 Bayer Ag, 5090 Leverkusen Unsymmetrische 1,4-Dihydropyridin-33-dicarbonsäureester, Verfahren zu ihrer Herstellung sowie ihre Verwendung als Arzneimittel
DE2117573C3 (de) * 1971-04-10 1978-07-27 Bayer Ag, 5090 Leverkusen Verfahren zur Herstellung von unsymmetrischen l,4-Dihydropyridin-3,5dicarbonsäureestern, sowie ihre Verwendung als Arzneimittel

Also Published As

Publication number Publication date
DE2650013B2 (de) 1980-06-12
GB1568740A (en) 1980-06-04
FR2369264B1 (es) 1980-06-13
DE2650013C3 (de) 1981-04-02
AT357162B (de) 1980-06-25
ATA773177A (de) 1979-11-15
US4166855A (en) 1979-09-04
DE2650013A1 (de) 1978-05-11
JPS577149B2 (es) 1982-02-09
JPS5356672A (en) 1978-05-23
CH633265A5 (de) 1982-11-30
CA1070314A (en) 1980-01-22
BE860248A (fr) 1978-04-28
AU3014777A (en) 1979-05-03
FR2369264A1 (fr) 1978-05-26
AU507892B2 (en) 1980-02-28
FI60705B (fi) 1981-11-30
NL7711827A (nl) 1978-05-03
CH635078A5 (de) 1983-03-15
SE7712108L (sv) 1978-05-01
FI773208A (fi) 1978-05-01
FI60705C (fi) 1982-03-10
SE433211B (sv) 1984-05-14

Similar Documents

Publication Publication Date Title
DE2962241D1 (en) Process for the preparation of derivatives of 1,4-dihydropyridine-3-carboxylic acid, derivatives of 1,4-dihydropyridine-3-carboxylic acid and the use of these derivatives for the preparation of 1,4-dihydropyridine-3,5-dicarboxylates
AU510353B2 (en) 1, 4-dihydro-pyridine derivatives
JPS55301A (en) 1,4-dihydropyridine-3,5-dicarboxylic ester derivative and its preparation
NL930034I1 (nl) Toepassing van 1,4-dihydro-2,6-dimethyl-4-(3-nitrofenyl)pyridine-3-beta-methoxy-ethylester-5-isopropylester ter bereiding van cerebraal werkzame geneesmiddelen
ES2002599A6 (es) Un procedimiento para la preparacion de la sal de besilato de amlodipina
ES485540A1 (es) Procedimiento para la obtencion de 1,4-dihidropiridinas, congrupos ester funcionalizados
AU518206B2 (en) Derivatives of 4-phenyl 1, 4-dihydropyridine-3, 5-dicarboxylate
JPS5762257A (en) 1,4-dihydropyridine-3,5-dicarboxylic acid ester or its salt
ES463646A1 (es) Procedimiento para la obtencion de 1,4-dihidro-2,6-dimetil- 4-(3-nitrofenil)-3,5-piridin-dicarboxilatos de isopropil-(2-propoxietilo).
FR2514761B1 (fr) Nouvelles 1,4-dihydropyridines, utiles notamment comme hypotenseurs
MY101142A (en) 1, 4-dihydropyridine derivative, process for production thereof, and pharmaceutical use thereof.
ES8604520A1 (es) Procedimiento para preparar derivados de 2(1h)-piridona
JPS5277073A (en) 1-carbamoyl-5-fluorouracil deruvative and anticancer drug containing s ame as effective component
JPS539783A (en) Stabilized composition containing cyanuric acid derivatives
AU498964B2 (en) Isobutyl methyl 1, 4-dihydro-2, 6-dimethyl-4-(2 nitrophenyl)-3, 5-pyridine-dicarboxylate
CS194774B2 (en) Process for preparing derivatives of 1,4-dihydropyridine suitable especially as antihypertensive and antianginar medicament
HUT44694A (en) Process for producing benzthiazinone derivatives, and fungicide compositions containing them as active components
JPS52131583A (en) Piperidine derivative and stabilizing composition containing same
DK165686A (da) 1,4-dihydropyridin-3,5-dicarboxylatderivater
ZA771378B (en) Method of producing albumin containing nutrient compositions
DE3476065D1 (en) L-arginine isoxicamate
IL50983A0 (en) 5-alkylureido-1,3,4-thiadiazol-2-yl-sulphonyl-acetic-acid derivatives,process for the preparation of said compounds and herbicidal compositions containing the same
AU575946B2 (en) 1,4-dihydro-2,6-dimethyl-4-(substituted phenyl)- 3,5-dicarboxylate derivatives
JPS5427559A (en) 1-(4-butyl) benzoylpyrrolidine and bactericides containing the same
FR2601701B1 (fr) Composition a base de chlorure de methylene - son utilisation pour le degraissage des metaux

Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19990503