JPS5356672A - Production of 1*44dihydroo2*66 dimethyll44*33nitropheny**3*55 pyridinedicarroxylic acid ester and use of same as pepipherl blood vessel dilator - Google Patents

Production of 1*44dihydroo2*66 dimethyll44*33nitropheny**3*55 pyridinedicarroxylic acid ester and use of same as pepipherl blood vessel dilator

Info

Publication number
JPS5356672A
JPS5356672A JP12881477A JP12881477A JPS5356672A JP S5356672 A JPS5356672 A JP S5356672A JP 12881477 A JP12881477 A JP 12881477A JP 12881477 A JP12881477 A JP 12881477A JP S5356672 A JPS5356672 A JP S5356672A
Authority
JP
Japan
Prior art keywords
pyridinedicarroxylic
pepipherl
production
acid ester
same
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP12881477A
Other languages
English (en)
Japanese (ja)
Other versions
JPS577149B2 (Direct
Inventor
Behingaa Eguberuto
Botsuzaato Furiidoritsuhi
Maiyaa Horusuto
Haize Arento
Katsuda Sutanisurafu
Sutetsuperu Kuruto
Fuaataa Burufu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer AG
Original Assignee
Bayer AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer AG filed Critical Bayer AG
Publication of JPS5356672A publication Critical patent/JPS5356672A/ja
Publication of JPS577149B2 publication Critical patent/JPS577149B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
    • C07D211/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
JP12881477A 1976-10-30 1977-10-28 Production of 1*44dihydroo2*66 dimethyll44*33nitropheny**3*55 pyridinedicarroxylic acid ester and use of same as pepipherl blood vessel dilator Granted JPS5356672A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2650013A DE2650013C3 (de) 1976-10-30 1976-10-30 1.4-Dihydro-2.6-dimethyl-4-(3-nitrophenyl)-3.5-pyridindicarbonsäureisopropyl-(2-propoxy-äthyl)-ester, Verfahren zu seiner Herstellung sowie ihn enthaltende Arzneimittel

Publications (2)

Publication Number Publication Date
JPS5356672A true JPS5356672A (en) 1978-05-23
JPS577149B2 JPS577149B2 (Direct) 1982-02-09

Family

ID=5992142

Family Applications (1)

Application Number Title Priority Date Filing Date
JP12881477A Granted JPS5356672A (en) 1976-10-30 1977-10-28 Production of 1*44dihydroo2*66 dimethyll44*33nitropheny**3*55 pyridinedicarroxylic acid ester and use of same as pepipherl blood vessel dilator

Country Status (14)

Country Link
US (1) US4166855A (Direct)
JP (1) JPS5356672A (Direct)
AT (1) AT357162B (Direct)
AU (1) AU507892B2 (Direct)
BE (1) BE860248A (Direct)
CA (1) CA1070314A (Direct)
CH (2) CH633265A5 (Direct)
DE (1) DE2650013C3 (Direct)
ES (1) ES463646A1 (Direct)
FI (1) FI60705C (Direct)
FR (1) FR2369264A1 (Direct)
GB (1) GB1568740A (Direct)
NL (1) NL7711827A (Direct)
SE (1) SE433211B (Direct)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS57175164A (en) * 1981-04-18 1982-10-28 Banyu Pharmaceut Co Ltd 1,4-dihydropyridine derivative and its preparation
JPS58185821U (ja) * 1982-06-02 1983-12-10 日産自動車株式会社 ウインドシ−ルド

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3208628A1 (de) * 1982-03-10 1983-09-22 Bayer Ag, 5090 Leverkusen Neue verbindungen, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel
DE3248548A1 (de) * 1982-12-29 1984-07-05 Heinrich Mack Nachf., 7918 Illertissen Acylderivate von 1,4:3,6-dianhydro-hexiten, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
DE3316510A1 (de) * 1983-05-06 1984-11-08 Bayer Ag Parenterale formulierung von nimodipin, ein verfahren zu ihrer herstellung sowie ihre verwendung bei der bekaempfung von erkrankungen
JPS60214778A (ja) * 1984-03-08 1985-10-28 Suntory Ltd Ν置換３，４−ジヒドロピリミジン誘導体ならびにその製造法および用途
DE3544692A1 (de) * 1985-12-18 1987-06-19 Bayer Ag Dihydropyridinspray, verfahren zu seiner herstellung und seine pharmazeutische verwendung
LV12200B (lv) * 1997-07-03 1999-04-20 Gun�rs DUBURS Antidiabētisks līdzeklis

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1670827C3 (de) * 1967-03-20 1974-10-24 Bayer Ag, 5090 Leverkusen 4-(2'-Nitrophenyl)-2,6-dimethyl-3,5-dicarbmethoxy-1,4-dihydropyridin
DE2117571C3 (de) * 1971-04-10 1979-10-11 Bayer Ag, 5090 Leverkusen Unsymmetrische 1,4-Dihydropyridin-33-dicarbonsäureester, Verfahren zu ihrer Herstellung sowie ihre Verwendung als Arzneimittel
DE2117573C3 (de) * 1971-04-10 1978-07-27 Bayer Ag, 5090 Leverkusen Verfahren zur Herstellung von unsymmetrischen l,4-Dihydropyridin-3,5dicarbonsäureestern, sowie ihre Verwendung als Arzneimittel

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS57175164A (en) * 1981-04-18 1982-10-28 Banyu Pharmaceut Co Ltd 1,4-dihydropyridine derivative and its preparation
JPS58185821U (ja) * 1982-06-02 1983-12-10 日産自動車株式会社 ウインドシ−ルド

Also Published As

Publication number Publication date
NL7711827A (nl) 1978-05-03
ES463646A1 (es) 1978-07-16
SE7712108L (sv) 1978-05-01
DE2650013B2 (de) 1980-06-12
FI60705B (fi) 1981-11-30
AU507892B2 (en) 1980-02-28
FR2369264A1 (fr) 1978-05-26
JPS577149B2 (Direct) 1982-02-09
AU3014777A (en) 1979-05-03
CH635078A5 (de) 1983-03-15
AT357162B (de) 1980-06-25
ATA773177A (de) 1979-11-15
SE433211B (sv) 1984-05-14
CH633265A5 (de) 1982-11-30
DE2650013C3 (de) 1981-04-02
FI60705C (fi) 1982-03-10
GB1568740A (en) 1980-06-04
FI773208A7 (fi) 1978-05-01
FR2369264B1 (Direct) 1980-06-13
DE2650013A1 (de) 1978-05-11
BE860248A (fr) 1978-04-28
US4166855A (en) 1979-09-04
CA1070314A (en) 1980-01-22

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