FR2368453A1 - Carbamates hydroxyles provenant de la reaction d'isocyanates avec des composes interessants du point de vue chimique - Google Patents

Carbamates hydroxyles provenant de la reaction d'isocyanates avec des composes interessants du point de vue chimique

Info

Publication number
FR2368453A1
FR2368453A1 FR7803364A FR7803364A FR2368453A1 FR 2368453 A1 FR2368453 A1 FR 2368453A1 FR 7803364 A FR7803364 A FR 7803364A FR 7803364 A FR7803364 A FR 7803364A FR 2368453 A1 FR2368453 A1 FR 2368453A1
Authority
FR
France
Prior art keywords
isocyanates
reaction
carbamates
hydroxyl
components
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7803364A
Other languages
English (en)
Other versions
FR2368453B1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Union Carbide Corp
Original Assignee
Union Carbide Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Union Carbide Corp filed Critical Union Carbide Corp
Publication of FR2368453A1 publication Critical patent/FR2368453A1/fr
Application granted granted Critical
Publication of FR2368453B1 publication Critical patent/FR2368453B1/fr
Granted legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531—Production of immunochemical test materials
    • G01N33/532—Production of labelled immunochemicals
    • G01N33/534—Production of labelled immunochemicals with radioactive label
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804—Compounds having Si-O-C linkages
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0005—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring the nitrogen atom being directly linked to the cyclopenta(a)hydro phenanthrene skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/0055—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 the 17-beta position being substituted by an uninterrupted chain of at least three carbon atoms which may or may not be branched, e.g. cholane or cholestane derivatives, optionally cyclised, e.g. 17-beta-phenyl or 17-beta-furyl derivatives
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/815—Test for named compound or class of compounds
    • Y10S436/817—Steroids or hormones

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Food Science & Technology (AREA)
  • Pathology (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Steroid Compounds (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Furan Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Saccharide Compounds (AREA)

Abstract

L'invention concerne des carbamates hydroxylés provenant de la réaction d'isocyanates avec divers composés des fluides biologiques. On les obtient par réaction d'un isocyanate portant un groupe hydroxy protégé par un groupe trihydrocarbylsiloxy avec un composé tel qu'un stéroïde ou une hormone et élimination du groupe protégeant la fonction hydroxy. Les derives hydroxylés ainsi obtenus sont utiles, après marquage par des atomes radio-actifs, pour l'analyse quantitative des réactions antigène-anticorps dans le sang.
FR7803364A 1976-05-17 1978-02-07 Carbamates hydroxyles provenant de la reaction d'isocyanates avec des composes interessants du point de vue chimique Granted FR2368453A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/687,149 US4115539A (en) 1976-05-17 1976-05-17 Analytical or clinical derivatives, tagged derivatives and methods of analysis using such derivatives

Publications (2)

Publication Number Publication Date
FR2368453A1 true FR2368453A1 (fr) 1978-05-19
FR2368453B1 FR2368453B1 (fr) 1981-10-02

Family

ID=24759277

Family Applications (3)

Application Number Title Priority Date Filing Date
FR7714947A Granted FR2369284A1 (fr) 1976-05-17 1977-05-16 Produits de reaction d'isocyanates silyles avec des composes interessants du point de vue chimiqu
FR7803365A Expired FR2368452B1 (fr) 1976-05-17 1978-02-07 Derives radio-iodes de carbamates hydroxyles et leur application a l'analyse de fluides biologiques
FR7803364A Granted FR2368453A1 (fr) 1976-05-17 1978-02-07 Carbamates hydroxyles provenant de la reaction d'isocyanates avec des composes interessants du point de vue chimique

Family Applications Before (2)

Application Number Title Priority Date Filing Date
FR7714947A Granted FR2369284A1 (fr) 1976-05-17 1977-05-16 Produits de reaction d'isocyanates silyles avec des composes interessants du point de vue chimiqu
FR7803365A Expired FR2368452B1 (fr) 1976-05-17 1978-02-07 Derives radio-iodes de carbamates hydroxyles et leur application a l'analyse de fluides biologiques

Country Status (13)

Country Link
US (1) US4115539A (fr)
JP (2) JPS5315359A (fr)
AU (1) AU519191B2 (fr)
BE (1) BE854692A (fr)
BR (1) BR7703146A (fr)
CA (1) CA1093486A (fr)
DE (1) DE2722038C2 (fr)
DK (1) DK213177A (fr)
FR (3) FR2369284A1 (fr)
GB (2) GB1586186A (fr)
IL (1) IL52095A0 (fr)
NL (1) NL7705411A (fr)
SE (2) SE447025B (fr)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2433509A1 (fr) * 1978-08-17 1980-03-14 Sheludyakov Viktor Procede de preparation d'isocyanates
US4256833A (en) * 1979-01-08 1981-03-17 Majid Ali Enzyme immunoassay for allergic disorders
US4358435A (en) * 1980-06-09 1982-11-09 The Research Foundation Of State University Of New York Ligand compositions and processes for their manufacture and their use in radioimmunoassay
US4595656A (en) * 1984-01-06 1986-06-17 Becton Dickinson & Company Coupling agents and products produced therefrom
US4670406A (en) * 1984-01-06 1987-06-02 Becton Dickinson And Company Tracers for use in assays
CA1290701C (fr) * 1984-07-05 1991-10-15 Jerald C. Nelson Cellule pour dialyse
US4736046A (en) * 1985-12-23 1988-04-05 The Dow Chemical Company β-isocyanato organosilanes
GB9625895D0 (en) 1996-12-13 1997-01-29 Riley Patrick A Novel compound useful as therapeutic agents and assay reagents
US7183319B2 (en) * 2000-07-26 2007-02-27 Patrick Anthony Riley Phenylethylamine derivatives and their use in the treatment of melanoma
EP2523966B1 (fr) 2010-01-15 2017-10-04 Suzhou Neupharma Co., Ltd Certaines entités chimiques, compositions, et procédés associés
CN102656179B (zh) 2010-08-28 2015-07-29 苏州润新生物科技有限公司 蟾蜍灵衍生物、其药物组合物及用途
CN103619865B (zh) * 2011-02-02 2016-10-12 苏州润新生物科技有限公司 某些化学个体、组合物及方法
CN109354598A (zh) 2012-04-29 2019-02-19 润新生物公司 化学个体、药物组合物及癌症治疗方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3953431A (en) * 1971-05-24 1976-04-27 Becton, Dickinson & Company Derivatives of digoxigenin
US3996344A (en) * 1972-05-15 1976-12-07 Biological Developments, Inc. Phenethylamine antigenic conjugates, their preparation, antibodies and use
US3843696A (en) * 1972-09-05 1974-10-22 Syva Co Methadone analog compounds
US3878187A (en) * 1972-09-11 1975-04-15 Syva Co Polypeptide derivatives of amphetamine and analogs for immunoassays
US3867366A (en) * 1972-11-06 1975-02-18 Synvar Associates A K A Syva C Opiate imidates and protein conjugates thereof
US3888866A (en) * 1973-06-01 1975-06-10 Syva Co Nitrogen derivatives of benzoyl ecgonine
SE396478B (sv) * 1974-04-03 1977-09-19 Pharmacia Ab Radioaktivt merkt antigen, hapten eller antikropp for anvendning vid radioimmunologiska bestemningsmetoder
US3963697A (en) * 1974-08-29 1976-06-15 Curtis Nuclear Corporation Labelled cardiotonic glycosides for use in radioimmunoassay
US3981982A (en) * 1974-09-11 1976-09-21 Abbott Laboratories Radioimmunoassay for determining the digoxin content of a sample

Also Published As

Publication number Publication date
CA1093486A (fr) 1981-01-13
SE8205750D0 (sv) 1982-10-08
FR2368452B1 (fr) 1985-09-06
IL52095A0 (en) 1977-07-31
SE446738B (sv) 1986-10-06
AU2518777A (en) 1978-11-23
AU519191B2 (en) 1981-11-19
GB1586185A (en) 1981-03-18
FR2368452A1 (fr) 1978-05-19
FR2369284B1 (fr) 1981-10-02
DK213177A (da) 1977-11-18
FR2369284A1 (fr) 1978-05-26
DE2722038A1 (de) 1977-12-15
GB1586186A (en) 1981-03-18
SE447025B (sv) 1986-10-20
SE8205750L (sv) 1982-10-08
DE2722038C2 (de) 1983-05-19
BE854692A (fr) 1977-11-16
US4115539A (en) 1978-09-19
JPS6332356B2 (fr) 1988-06-29
JPS5315359A (en) 1978-02-13
SE7705191L (sv) 1977-11-18
JPS5823699A (ja) 1983-02-12
NL7705411A (nl) 1977-11-21
BR7703146A (pt) 1978-04-04
FR2368453B1 (fr) 1981-10-02

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TP Transmission of property
ST Notification of lapse