FR2368452B1 - Derives radio-iodes de carbamates hydroxyles et leur application a l'analyse de fluides biologiques - Google Patents
Derives radio-iodes de carbamates hydroxyles et leur application a l'analyse de fluides biologiquesInfo
- Publication number
- FR2368452B1 FR2368452B1 FR7803365A FR7803365A FR2368452B1 FR 2368452 B1 FR2368452 B1 FR 2368452B1 FR 7803365 A FR7803365 A FR 7803365A FR 7803365 A FR7803365 A FR 7803365A FR 2368452 B1 FR2368452 B1 FR 2368452B1
- Authority
- FR
- France
- Prior art keywords
- carbamates
- hydroxyl
- radio
- analysis
- application
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- KXDHJXZQYSOELW-UHFFFAOYSA-M Carbamate Chemical compound NC([O-])=O KXDHJXZQYSOELW-UHFFFAOYSA-M 0.000 title 1
- 239000013060 biological fluid Substances 0.000 title 1
- TUJKJAMUKRIRHC-UHFFFAOYSA-N hydroxyl Chemical class [OH] TUJKJAMUKRIRHC-UHFFFAOYSA-N 0.000 title 1
- XMBWDFGMSWQBCA-RNFDNDRNSA-M iodine-131(1-) Chemical class [131I-] XMBWDFGMSWQBCA-RNFDNDRNSA-M 0.000 title 1
- WYURNTSHIVDZCO-UHFFFAOYSA-N Tetrahydrofuran Chemical compound C1CCOC1 WYURNTSHIVDZCO-UHFFFAOYSA-N 0.000 abstract 2
- ZMANZCXQSJIPKH-UHFFFAOYSA-N Triethylamine Chemical compound CCN(CC)CC ZMANZCXQSJIPKH-UHFFFAOYSA-N 0.000 abstract 2
- 239000003153 chemical reaction reagent Substances 0.000 abstract 2
- IJOOHPMOJXWVHK-UHFFFAOYSA-N chlorotrimethylsilane Chemical compound C[Si](C)(C)Cl IJOOHPMOJXWVHK-UHFFFAOYSA-N 0.000 abstract 2
- DZGWFCGJZKJUFP-UHFFFAOYSA-N Tyramine Natural products NCCC1=CC=C(O)C=C1 DZGWFCGJZKJUFP-UHFFFAOYSA-N 0.000 abstract 1
- DORHGRMBOUREIV-UHFFFAOYSA-N [4-(2-isocyanatoethyl)phenoxy]-trimethylsilane Chemical compound C[Si](C)(C)OC1=CC=C(CCN=C=O)C=C1 DORHGRMBOUREIV-UHFFFAOYSA-N 0.000 abstract 1
- 125000002723 alicyclic group Chemical group 0.000 abstract 1
- 125000002877 alkyl aryl group Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 125000003710 aryl alkyl group Chemical group 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 238000003556 assay Methods 0.000 abstract 1
- 210000001124 body fluid Anatomy 0.000 abstract 1
- 239000010839 body fluid Substances 0.000 abstract 1
- 230000005587 bubbling Effects 0.000 abstract 1
- 239000012948 isocyanate Substances 0.000 abstract 1
- 150000002513 isocyanates Chemical class 0.000 abstract 1
- 238000002372 labelling Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- YLQBMQCUIZJEEH-UHFFFAOYSA-N tetrahydrofuran Natural products C=1C=COC=1 YLQBMQCUIZJEEH-UHFFFAOYSA-N 0.000 abstract 1
- 239000005051 trimethylchlorosilane Substances 0.000 abstract 1
- 229960003732 tyramine Drugs 0.000 abstract 1
- DZGWFCGJZKJUFP-UHFFFAOYSA-O tyraminium Chemical compound [NH3+]CCC1=CC=C(O)C=C1 DZGWFCGJZKJUFP-UHFFFAOYSA-O 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/531—Production of immunochemical test materials
- G01N33/532—Production of labelled immunochemicals
- G01N33/534—Production of labelled immunochemicals with radioactive label
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
- C07F7/1804—Compounds having Si-O-C linkages
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
- C07J41/0005—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring the nitrogen atom being directly linked to the cyclopenta(a)hydro phenanthrene skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
- C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
- C07J41/0055—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 the 17-beta position being substituted by an uninterrupted chain of at least three carbon atoms which may or may not be branched, e.g. cholane or cholestane derivatives, optionally cyclised, e.g. 17-beta-phenyl or 17-beta-furyl derivatives
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/815—Test for named compound or class of compounds
- Y10S436/817—Steroids or hormones
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Food Science & Technology (AREA)
- Pathology (AREA)
- Cell Biology (AREA)
- Biotechnology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Physics & Mathematics (AREA)
- Microbiology (AREA)
- Steroid Compounds (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Furan Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US05/687,149 US4115539A (en) | 1976-05-17 | 1976-05-17 | Analytical or clinical derivatives, tagged derivatives and methods of analysis using such derivatives |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FR2368452A1 FR2368452A1 (fr) | 1978-05-19 |
| FR2368452B1 true FR2368452B1 (fr) | 1985-09-06 |
Family
ID=24759277
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR7714947A Granted FR2369284A1 (fr) | 1976-05-17 | 1977-05-16 | Produits de reaction d'isocyanates silyles avec des composes interessants du point de vue chimiqu |
| FR7803365A Expired FR2368452B1 (fr) | 1976-05-17 | 1978-02-07 | Derives radio-iodes de carbamates hydroxyles et leur application a l'analyse de fluides biologiques |
| FR7803364A Granted FR2368453A1 (fr) | 1976-05-17 | 1978-02-07 | Carbamates hydroxyles provenant de la reaction d'isocyanates avec des composes interessants du point de vue chimique |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR7714947A Granted FR2369284A1 (fr) | 1976-05-17 | 1977-05-16 | Produits de reaction d'isocyanates silyles avec des composes interessants du point de vue chimiqu |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR7803364A Granted FR2368453A1 (fr) | 1976-05-17 | 1978-02-07 | Carbamates hydroxyles provenant de la reaction d'isocyanates avec des composes interessants du point de vue chimique |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US4115539A (fr) |
| JP (2) | JPS5315359A (fr) |
| AU (1) | AU519191B2 (fr) |
| BE (1) | BE854692A (fr) |
| BR (1) | BR7703146A (fr) |
| CA (1) | CA1093486A (fr) |
| DE (1) | DE2722038C2 (fr) |
| DK (1) | DK213177A (fr) |
| FR (3) | FR2369284A1 (fr) |
| GB (2) | GB1586186A (fr) |
| IL (1) | IL52095A0 (fr) |
| NL (1) | NL7705411A (fr) |
| SE (2) | SE447025B (fr) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2433509A1 (fr) * | 1978-08-17 | 1980-03-14 | Sheludyakov Viktor | Procede de preparation d'isocyanates |
| US4256833A (en) * | 1979-01-08 | 1981-03-17 | Majid Ali | Enzyme immunoassay for allergic disorders |
| US4358435A (en) * | 1980-06-09 | 1982-11-09 | The Research Foundation Of State University Of New York | Ligand compositions and processes for their manufacture and their use in radioimmunoassay |
| US4595656A (en) * | 1984-01-06 | 1986-06-17 | Becton Dickinson & Company | Coupling agents and products produced therefrom |
| US4670406A (en) * | 1984-01-06 | 1987-06-02 | Becton Dickinson And Company | Tracers for use in assays |
| CA1290701C (fr) * | 1984-07-05 | 1991-10-15 | Jerald C. Nelson | Cellule pour dialyse |
| US4736046A (en) * | 1985-12-23 | 1988-04-05 | The Dow Chemical Company | β-isocyanato organosilanes |
| GB9625895D0 (en) | 1996-12-13 | 1997-01-29 | Riley Patrick A | Novel compound useful as therapeutic agents and assay reagents |
| US7183319B2 (en) * | 2000-07-26 | 2007-02-27 | Patrick Anthony Riley | Phenylethylamine derivatives and their use in the treatment of melanoma |
| EP2523966B1 (fr) | 2010-01-15 | 2017-10-04 | Suzhou Neupharma Co., Ltd | Certaines entités chimiques, compositions, et procédés associés |
| CN102656179B (zh) | 2010-08-28 | 2015-07-29 | 苏州润新生物科技有限公司 | 蟾蜍灵衍生物、其药物组合物及用途 |
| CN103619865B (zh) * | 2011-02-02 | 2016-10-12 | 苏州润新生物科技有限公司 | 某些化学个体、组合物及方法 |
| CN109354598A (zh) | 2012-04-29 | 2019-02-19 | 润新生物公司 | 化学个体、药物组合物及癌症治疗方法 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3953431A (en) * | 1971-05-24 | 1976-04-27 | Becton, Dickinson & Company | Derivatives of digoxigenin |
| US3996344A (en) * | 1972-05-15 | 1976-12-07 | Biological Developments, Inc. | Phenethylamine antigenic conjugates, their preparation, antibodies and use |
| US3843696A (en) * | 1972-09-05 | 1974-10-22 | Syva Co | Methadone analog compounds |
| US3878187A (en) * | 1972-09-11 | 1975-04-15 | Syva Co | Polypeptide derivatives of amphetamine and analogs for immunoassays |
| US3867366A (en) * | 1972-11-06 | 1975-02-18 | Synvar Associates A K A Syva C | Opiate imidates and protein conjugates thereof |
| US3888866A (en) * | 1973-06-01 | 1975-06-10 | Syva Co | Nitrogen derivatives of benzoyl ecgonine |
| SE396478B (sv) * | 1974-04-03 | 1977-09-19 | Pharmacia Ab | Radioaktivt merkt antigen, hapten eller antikropp for anvendning vid radioimmunologiska bestemningsmetoder |
| US3963697A (en) * | 1974-08-29 | 1976-06-15 | Curtis Nuclear Corporation | Labelled cardiotonic glycosides for use in radioimmunoassay |
| US3981982A (en) * | 1974-09-11 | 1976-09-21 | Abbott Laboratories | Radioimmunoassay for determining the digoxin content of a sample |
-
1976
- 1976-05-17 US US05/687,149 patent/US4115539A/en not_active Expired - Lifetime
-
1977
- 1977-05-04 SE SE7705191A patent/SE447025B/xx not_active IP Right Cessation
- 1977-05-16 CA CA278,492A patent/CA1093486A/fr not_active Expired
- 1977-05-16 GB GB25202/79A patent/GB1586186A/en not_active Expired
- 1977-05-16 DK DK213177A patent/DK213177A/da unknown
- 1977-05-16 NL NL7705411A patent/NL7705411A/xx not_active Application Discontinuation
- 1977-05-16 JP JP5553677A patent/JPS5315359A/ja active Pending
- 1977-05-16 DE DE2722038A patent/DE2722038C2/de not_active Expired
- 1977-05-16 GB GB20472/77A patent/GB1586185A/en not_active Expired
- 1977-05-16 BE BE177621A patent/BE854692A/fr unknown
- 1977-05-16 IL IL52095A patent/IL52095A0/xx unknown
- 1977-05-16 FR FR7714947A patent/FR2369284A1/fr active Granted
- 1977-05-16 BR BR7703146A patent/BR7703146A/pt unknown
- 1977-05-17 AU AU25187/77A patent/AU519191B2/en not_active Ceased
-
1978
- 1978-02-07 FR FR7803365A patent/FR2368452B1/fr not_active Expired
- 1978-02-07 FR FR7803364A patent/FR2368453A1/fr active Granted
-
1982
- 1982-06-30 JP JP57111828A patent/JPS5823699A/ja active Granted
- 1982-10-08 SE SE8205750A patent/SE446738B/sv not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| CA1093486A (fr) | 1981-01-13 |
| SE8205750D0 (sv) | 1982-10-08 |
| IL52095A0 (en) | 1977-07-31 |
| SE446738B (sv) | 1986-10-06 |
| AU2518777A (en) | 1978-11-23 |
| AU519191B2 (en) | 1981-11-19 |
| GB1586185A (en) | 1981-03-18 |
| FR2368452A1 (fr) | 1978-05-19 |
| FR2369284B1 (fr) | 1981-10-02 |
| DK213177A (da) | 1977-11-18 |
| FR2369284A1 (fr) | 1978-05-26 |
| DE2722038A1 (de) | 1977-12-15 |
| GB1586186A (en) | 1981-03-18 |
| SE447025B (sv) | 1986-10-20 |
| SE8205750L (sv) | 1982-10-08 |
| DE2722038C2 (de) | 1983-05-19 |
| BE854692A (fr) | 1977-11-16 |
| US4115539A (en) | 1978-09-19 |
| JPS6332356B2 (fr) | 1988-06-29 |
| JPS5315359A (en) | 1978-02-13 |
| SE7705191L (sv) | 1977-11-18 |
| JPS5823699A (ja) | 1983-02-12 |
| NL7705411A (nl) | 1977-11-21 |
| BR7703146A (pt) | 1978-04-04 |
| FR2368453B1 (fr) | 1981-10-02 |
| FR2368453A1 (fr) | 1978-05-19 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| TP | Transmission of property | ||
| ST | Notification of lapse |