FR2364906A1 - Nouvelle forme polymorphique de la cimetidine - Google Patents
Nouvelle forme polymorphique de la cimetidineInfo
- Publication number
- FR2364906A1 FR2364906A1 FR7727887A FR7727887A FR2364906A1 FR 2364906 A1 FR2364906 A1 FR 2364906A1 FR 7727887 A FR7727887 A FR 7727887A FR 7727887 A FR7727887 A FR 7727887A FR 2364906 A1 FR2364906 A1 FR 2364906A1
- Authority
- FR
- France
- Prior art keywords
- methyl
- polymorphic form
- guanidine
- cyano
- cimetidine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 229960001380 cimetidine Drugs 0.000 title 1
- CCGSUNCLSOWKJO-UHFFFAOYSA-N cimetidine Chemical compound N#CNC(=N/C)\NCCSCC1=NC=N[C]1C CCGSUNCLSOWKJO-UHFFFAOYSA-N 0.000 title 1
- 239000003485 histamine H2 receptor antagonist Substances 0.000 title 1
- ZRALSGWEFCBTJO-UHFFFAOYSA-N Guanidine Chemical compound NC(N)=N ZRALSGWEFCBTJO-UHFFFAOYSA-N 0.000 abstract 2
- CHJJGSNFBQVOTG-UHFFFAOYSA-N N-methyl-guanidine Natural products CNC(N)=N CHJJGSNFBQVOTG-UHFFFAOYSA-N 0.000 abstract 1
- SWSQBOPZIKWTGO-UHFFFAOYSA-N dimethylaminoamidine Natural products CN(C)C(N)=N SWSQBOPZIKWTGO-UHFFFAOYSA-N 0.000 abstract 1
- 238000002329 infrared spectrum Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB3906576A GB1543238A (en) | 1976-09-21 | 1976-09-21 | Polymorph of cimetidine |
| GB271677 | 1977-01-24 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| FR2364906A1 true FR2364906A1 (fr) | 1978-04-14 |
Family
ID=26237687
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR7727887A Withdrawn FR2364906A1 (fr) | 1976-09-21 | 1977-09-15 | Nouvelle forme polymorphique de la cimetidine |
Country Status (10)
| Country | Link |
|---|---|
| JP (1) | JPS5340771A (xx) |
| AU (1) | AU510629B2 (xx) |
| BE (1) | BE858432A (xx) |
| CA (1) | CA1096387A (xx) |
| DE (1) | DE2742531A1 (xx) |
| FR (1) | FR2364906A1 (xx) |
| IE (1) | IE45873B1 (xx) |
| IL (1) | IL52784A (xx) |
| LU (1) | LU78142A1 (xx) |
| NZ (1) | NZ184893A (xx) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS56104868A (en) * | 1980-01-24 | 1981-08-20 | Fujimoto Seiyaku Kk | Conversion between polymorphous crystals of cimetidine |
| JPS56164122A (en) * | 1980-05-21 | 1981-12-17 | Fujimoto Seiyaku Kk | Drug composition comprising cimetidine as main agent |
| HU185636B (en) * | 1981-06-26 | 1985-03-28 | Richter Gedeon Vegyeszet | Process for preparing new cimetidine-hydrate /cimetidine-h/ |
| HU185457B (en) * | 1981-09-25 | 1985-02-28 | Richter Gedeon Vegyeszet | Process for preparating cimetidine-z |
| JPS5888366A (ja) * | 1981-11-19 | 1983-05-26 | Fujimoto Seiyaku Kk | グアニジン誘導体の製造法 |
| JPS59128375A (ja) * | 1983-01-10 | 1984-07-24 | Tokawa Tetsuo | イミダゾ−ル系化合物の製法 |
| JPS59130274A (ja) * | 1983-01-14 | 1984-07-26 | Tokawa Tetsuo | イミダゾ−ル系化合物の製法 |
| JPS59130273A (ja) * | 1983-01-14 | 1984-07-26 | Tokawa Tetsuo | イミダゾ−ル系化合物の製造法 |
| HU196184B (en) * | 1986-09-11 | 1988-10-28 | Richter Gedeon Vegyeszet | Process for producing cimetidine-a modification |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL7510344A (nl) * | 1974-09-02 | 1976-03-04 | Smith Kline French Lab | Werkwijze voor het bereiden van farmacologisch actieve verbindingen. |
| NL7510334A (nl) * | 1974-09-02 | 1976-03-04 | Smith Kline French Lab | Werkwijze voor het bereiden van guanidineverbin- dingen. |
| FR2321490A1 (fr) * | 1975-08-20 | 1977-03-18 | Smithkline Corp | Procede de preparation de 4-(hydroxymethyl) imidazoles |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1397436A (en) * | 1972-09-05 | 1975-06-11 | Smith Kline French Lab | Heterocyclic n-cyanoguinidines |
-
1977
- 1977-08-10 NZ NZ184893A patent/NZ184893A/xx unknown
- 1977-08-22 IL IL52784A patent/IL52784A/xx unknown
- 1977-09-06 BE BE180694A patent/BE858432A/xx not_active IP Right Cessation
- 1977-09-14 AU AU28792/77A patent/AU510629B2/en not_active Expired
- 1977-09-15 FR FR7727887A patent/FR2364906A1/fr not_active Withdrawn
- 1977-09-16 JP JP11209377A patent/JPS5340771A/ja active Granted
- 1977-09-19 LU LU78142A patent/LU78142A1/xx unknown
- 1977-09-20 CA CA287,087A patent/CA1096387A/en not_active Expired
- 1977-09-21 IE IE1932/77A patent/IE45873B1/en not_active IP Right Cessation
- 1977-09-21 DE DE19772742531 patent/DE2742531A1/de not_active Withdrawn
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL7510344A (nl) * | 1974-09-02 | 1976-03-04 | Smith Kline French Lab | Werkwijze voor het bereiden van farmacologisch actieve verbindingen. |
| NL7510334A (nl) * | 1974-09-02 | 1976-03-04 | Smith Kline French Lab | Werkwijze voor het bereiden van guanidineverbin- dingen. |
| FR2321490A1 (fr) * | 1975-08-20 | 1977-03-18 | Smithkline Corp | Procede de preparation de 4-(hydroxymethyl) imidazoles |
Also Published As
| Publication number | Publication date |
|---|---|
| LU78142A1 (xx) | 1978-01-17 |
| JPS5340771A (en) | 1978-04-13 |
| IE45873L (en) | 1978-07-24 |
| AU510629B2 (en) | 1980-07-03 |
| CA1096387A (en) | 1981-02-24 |
| AU2879277A (en) | 1979-03-22 |
| JPS6222967B2 (xx) | 1987-05-20 |
| NZ184893A (en) | 1980-11-28 |
| IL52784A0 (en) | 1977-10-31 |
| BE858432A (fr) | 1978-03-06 |
| IL52784A (en) | 1980-09-16 |
| IE45873B1 (en) | 1982-12-15 |
| DE2742531A1 (de) | 1978-03-23 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ST | Notification of lapse |