FR2364456A1 - Procede pour deceler et identifier des facteurs de rhumatismes - Google Patents

Procede pour deceler et identifier des facteurs de rhumatismes

Info

Publication number
FR2364456A1
FR2364456A1 FR7722925A FR7722925A FR2364456A1 FR 2364456 A1 FR2364456 A1 FR 2364456A1 FR 7722925 A FR7722925 A FR 7722925A FR 7722925 A FR7722925 A FR 7722925A FR 2364456 A1 FR2364456 A1 FR 2364456A1
Authority
FR
France
Prior art keywords
rheumatism
factors
identification
detection
precipitate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7722925A
Other languages
English (en)
Other versions
FR2364456B1 (fr
Inventor
Henning Roger Hallgren
Leif Edvin Wide
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Phadia AB
Original Assignee
Pharmacia Diagnostics AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmacia Diagnostics AB filed Critical Pharmacia Diagnostics AB
Publication of FR2364456A1 publication Critical patent/FR2364456A1/fr
Application granted granted Critical
Publication of FR2364456B1 publication Critical patent/FR2364456B1/fr
Granted legal-status Critical Current

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/564Immunoassay; Biospecific binding assay; Materials therefor for pre-existing immune complex or autoimmune disease, i.e. systemic lupus erythematosus, rheumatoid arthritis, multiple sclerosis, rheumatoid factors or complement components C1-C9
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/962Prevention or removal of interfering materials or reactants or other treatment to enhance results, e.g. determining or preventing nonspecific binding
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00Chemistry: analytical and immunological testing
    • Y10S436/80Fluorescent dyes, e.g. rhodamine
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00Chemistry: analytical and immunological testing
    • Y10S436/804Radioisotope, e.g. radioimmunoassay
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00Chemistry: analytical and immunological testing
    • Y10S436/819Multifunctional antigen or antibody
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00Chemistry: analytical and immunological testing
    • Y10S436/821Chemistry: analytical and immunological testing involving complement factors or complement systems
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00Chemistry: analytical and immunological testing
    • Y10S436/826Additives, e.g. buffers, diluents, preservatives

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Engineering & Computer Science (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Rehabilitation Therapy (AREA)
  • Biotechnology (AREA)
  • Rheumatology (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)

Abstract

Procédé pour déceler et identifier des facteurs de rhumatismes. On fait réagir, en présence d'un quelconque facteur complémentaire désactivé d'une manière connue en soi, un échantillon aqueux avec de l'immunoglobuline agrégée soluble identifiée à l'aide de un ou plusieurs atomes ou groupements pouvant être déterminés analytiquement, afin de former des agrégats entre les facteurs de rhumatismes et ladite immunoglobuline agrégée identifiée, lesdits agrégats étant précipités, après quoi ledit précipité est séparé et lesdits atomes ou groupements sont déterminés dans le précipité et/ou dans la solution. Application à la détermination de la présence de facteurs de rhumatismes en vue d'une thérapie subséquente appropriée.
FR7722925A 1976-09-08 1977-07-26 Procede pour deceler et identifier des facteurs de rhumatismes Granted FR2364456A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE7609906A SE441042B (sv) 1976-09-08 1976-09-08 Sett att pavisa rheumatoida faktorer

Publications (2)

Publication Number Publication Date
FR2364456A1 true FR2364456A1 (fr) 1978-04-07
FR2364456B1 FR2364456B1 (fr) 1981-08-28

Family

ID=20328828

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7722925A Granted FR2364456A1 (fr) 1976-09-08 1977-07-26 Procede pour deceler et identifier des facteurs de rhumatismes

Country Status (8)

Country Link
US (1) US4153417A (fr)
JP (1) JPS6057544B2 (fr)
CA (1) CA1076937A (fr)
DE (1) DE2707881C2 (fr)
FR (1) FR2364456A1 (fr)
GB (1) GB1576400A (fr)
NL (1) NL7708078A (fr)
SE (1) SE441042B (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2521303A1 (fr) * 1982-02-08 1983-08-12 Abbott Lab Procede de determination immunologique d'anticorps de type immunoglobuline de classe specifique

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4302536A (en) * 1978-08-15 1981-11-24 Longenecker Robert W Colorimetric immunoassay process
US4342566A (en) * 1980-02-22 1982-08-03 Scripps Clinic & Research Foundation Solid phase anti-C3 assay for detection of immune complexes
US4450231A (en) * 1982-03-31 1984-05-22 Biostar Medical Products, Inc. Immunoassay for determination of immune complexes with polymer-coated plastic base
US4582793A (en) * 1982-10-29 1986-04-15 Research Corporation Anti-RNA polymerase I antibody test for the diagnosis of rheumatological diseases
SE8304836D0 (sv) * 1983-09-09 1983-09-09 Pharmacia Ab Sett att bestemma forendringar i ledbrosk
CA1261257A (fr) * 1984-09-19 1989-09-26 Helgi Valdimarsson Valeur de diagnostic des isotypes du facteur rhumatoide et leur association avec la maladie active
US4914041A (en) * 1988-02-12 1990-04-03 Beckman Instruments, Inc. Reagent and method for detecting rheumatoid factor
EP0434765B1 (fr) * 1988-09-30 1995-11-08 Neorx Corporation Conjugues de substance de ciblage et d'agent diagnostique/therapeutique comportant des liaisons de base de schiff
US5066789A (en) * 1988-09-30 1991-11-19 Neorx Corporation Targeting substance-diagnostic/therapeutic agent conjugates having Schiff base linkages
US4986979A (en) * 1989-03-14 1991-01-22 Neorx Corporation Imaging tissue sites of inflammation
JPH02144560U (fr) * 1989-05-12 1990-12-07
JPH11322798A (ja) * 1998-05-14 1999-11-24 Matsushita Electric Ind Co Ltd 色素標識重合抗体およびその製造方法
JP3601972B2 (ja) * 1998-05-14 2004-12-15 松下電器産業株式会社 色素標識タンパク質複合体およびその製造方法
JP3625250B2 (ja) * 1998-05-14 2005-03-02 松下電器産業株式会社 色素標識重合抗体およびその製造方法
US6303759B1 (en) 1996-11-08 2001-10-16 Matsushita Electric Industrial Co., Ltd. Dye-labeled and polymerized antibody and method for preparing the same
US6303758B1 (en) 1996-11-08 2001-10-16 Matsushita Electric Industrial Co., Ltd. Dye-labeled and polymerized antibody and method for preparing the same
US6300480B1 (en) 1996-11-08 2001-10-09 Matsushita Electric Industrial Co., Ltd. Dye-labeled protein conjugate and method for preparing the same
CN1454313A (zh) 2000-07-14 2003-11-05 免疫公司 通过磁性纳米颗粒的受控聚集而提高分离效率
US20060159680A1 (en) * 2005-01-14 2006-07-20 Smith Henry J Targeted apherisis for the treatment of rheumatoid arthritis
US20130068691A1 (en) * 2011-08-05 2013-03-21 Henry John Smith Targeted apheresis for the treatment of rheumatoid arthritis and immune disorders

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1484727A (fr) * 1966-04-19 1967-06-16 Réactif immunologique et son procédé d'obtention
GB1179435A (en) * 1966-06-17 1970-01-28 Ortho Pharma Corp Stable Reagent for the Detection of Rheumatoid Arthritis
US3689632A (en) * 1969-01-06 1972-09-05 Kowa Co Rheumatoid agglutination test and reagent
GB1508132A (en) * 1974-05-20 1978-04-19 Technicon Instr Analysis of biological fluids

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
CA1971 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2521303A1 (fr) * 1982-02-08 1983-08-12 Abbott Lab Procede de determination immunologique d'anticorps de type immunoglobuline de classe specifique

Also Published As

Publication number Publication date
US4153417A (en) 1979-05-08
DE2707881C2 (de) 1985-05-30
NL7708078A (nl) 1978-03-10
JPS6057544B2 (ja) 1985-12-16
SE7609906L (sv) 1978-03-09
JPS5334918A (en) 1978-03-31
CA1076937A (fr) 1980-05-06
DE2707881A1 (de) 1978-03-09
GB1576400A (en) 1980-10-08
SE441042B (sv) 1985-09-02
FR2364456B1 (fr) 1981-08-28

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ST Notification of lapse