FR2364220A1 - Nouveaux derives amide de la vlb, de la leurosidine, de la leurocristine et d'autres alcaloides apparentes - Google Patents

Nouveaux derives amide de la vlb, de la leurosidine, de la leurocristine et d'autres alcaloides apparentes

Info

Publication number
FR2364220A1
FR2364220A1 FR7727080A FR7727080A FR2364220A1 FR 2364220 A1 FR2364220 A1 FR 2364220A1 FR 7727080 A FR7727080 A FR 7727080A FR 7727080 A FR7727080 A FR 7727080A FR 2364220 A1 FR2364220 A1 FR 2364220A1
Authority
FR
France
Prior art keywords
leurocristine
leurosidine
vlb
related alkaloids
amid derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7727080A
Other languages
English (en)
French (fr)
Other versions
FR2364220B1 (sk
Inventor
George Joseph Cullinan
Koert Gerzon
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eli Lilly and Co
Original Assignee
Eli Lilly and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly and Co filed Critical Eli Lilly and Co
Publication of FR2364220A1 publication Critical patent/FR2364220A1/fr
Application granted granted Critical
Publication of FR2364220B1 publication Critical patent/FR2364220B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
    • C07D519/04—Dimeric indole alkaloids, e.g. vincaleucoblastine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Peptides Or Proteins (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
FR7727080A 1976-09-08 1977-09-07 Nouveaux derives amide de la vlb, de la leurosidine, de la leurocristine et d'autres alcaloides apparentes Granted FR2364220A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US72165076A 1976-09-08 1976-09-08

Publications (2)

Publication Number Publication Date
FR2364220A1 true FR2364220A1 (fr) 1978-04-07
FR2364220B1 FR2364220B1 (sk) 1980-04-25

Family

ID=24898757

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7727080A Granted FR2364220A1 (fr) 1976-09-08 1977-09-07 Nouveaux derives amide de la vlb, de la leurosidine, de la leurocristine et d'autres alcaloides apparentes

Country Status (27)

Country Link
JP (1) JPS5340799A (sk)
AR (3) AR226411A1 (sk)
AT (1) AT360513B (sk)
AU (1) AU511055B2 (sk)
BE (1) BE858451A (sk)
CA (1) CA1082179A (sk)
CH (1) CH631990A5 (sk)
DD (1) DD133055A5 (sk)
DE (1) DE2739443A1 (sk)
DK (1) DK146822C (sk)
ES (1) ES462229A1 (sk)
FR (1) FR2364220A1 (sk)
GB (1) GB1586709A (sk)
GR (1) GR69783B (sk)
HU (1) HU180722B (sk)
IE (1) IE45558B1 (sk)
IL (1) IL52731A0 (sk)
MX (1) MX4740E (sk)
NL (1) NL7709806A (sk)
NZ (1) NZ184932A (sk)
PH (1) PH14771A (sk)
PL (1) PL104309B1 (sk)
PT (1) PT66984B (sk)
RO (3) RO77922A (sk)
SE (1) SE434953B (sk)
YU (1) YU209777A (sk)
ZA (1) ZA774988B (sk)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2435480A1 (fr) * 1978-05-15 1980-04-04 Lilly Co Eli Dimeres pontes d'alcaloides de catharanthus et leur utilisation therapeutique
FR2438659A1 (fr) * 1978-10-10 1980-05-09 Lilly Co Eli Procede de preparation du sulfate de vindesine

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
USRE30561E (en) * 1976-12-06 1981-03-31 Eli Lilly And Company Vinca alkaloid intermediates
US4357334A (en) 1980-03-20 1982-11-02 Eli Lilly And Company Use of VLB 3-(2-chloroethyl) carboxamide in treating neoplasms
OA06421A (fr) * 1980-06-10 1981-09-30 Omnium Chimique Sa Procédé de préparation de dérivés N-(vinblastinoyl-23) d'acides aminés et de peptides.
US4362664A (en) * 1980-12-29 1982-12-07 Eli Lilly And Company Vinblastine oxazolidinedione disulfides and related compounds
JPH075608B2 (ja) * 1986-01-13 1995-01-25 イ−ル−セルタ−ク ソシエテ アノニム ビンブラスチン誘導体

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR204004A1 (es) * 1973-04-02 1975-11-12 Lilly Co Eli Procedimientos para preparar derivados de vinblastina leurosidina y leurocristina
IL48685A (en) * 1975-01-09 1980-03-31 Lilly Co Eli Amides of vincadioline and vinblastine

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2435480A1 (fr) * 1978-05-15 1980-04-04 Lilly Co Eli Dimeres pontes d'alcaloides de catharanthus et leur utilisation therapeutique
FR2438052A1 (fr) * 1978-05-15 1980-04-30 Lilly Co Eli Nouveau procede de preparation de dimeres pontes d'alcaloides de catharanthus et composes intermediaires
FR2438659A1 (fr) * 1978-10-10 1980-05-09 Lilly Co Eli Procede de preparation du sulfate de vindesine

Also Published As

Publication number Publication date
IL52731A0 (en) 1977-10-31
RO72474A (ro) 1982-05-10
CA1082179A (en) 1980-07-22
DK398577A (da) 1978-03-09
MX4740E (es) 1982-08-25
GR69783B (sk) 1982-07-07
NL7709806A (nl) 1978-03-10
ES462229A1 (es) 1978-07-16
PT66984B (en) 1979-02-13
DE2739443A1 (de) 1978-03-09
BE858451A (fr) 1978-03-07
FR2364220B1 (sk) 1980-04-25
YU209777A (en) 1982-08-31
AT360513B (de) 1981-01-12
ZA774988B (en) 1979-03-28
IE45558B1 (en) 1982-09-22
CH631990A5 (en) 1982-09-15
ATA644277A (de) 1980-06-15
JPS624398B2 (sk) 1987-01-30
SE434953B (sv) 1984-08-27
JPS5340799A (en) 1978-04-13
DE2739443C2 (sk) 1991-08-14
AU2803977A (en) 1979-02-22
RO77921A (ro) 1981-12-25
DD133055A5 (de) 1978-11-29
IE771700L (en) 1978-03-08
PL200607A1 (pl) 1978-05-22
AR226411A1 (es) 1982-07-15
DK146822C (da) 1984-06-25
PH14771A (en) 1981-12-09
SE7710059L (sv) 1978-03-09
GB1586709A (en) 1981-03-25
DK146822B (da) 1984-01-16
PL104309B1 (pl) 1979-08-31
HU180722B (en) 1983-04-29
NZ184932A (en) 1979-11-01
AR230642A1 (es) 1984-05-31
AR231643A1 (es) 1985-01-31
PT66984A (en) 1977-10-01
RO77922A (ro) 1981-12-25
AU511055B2 (en) 1980-07-24

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Legal Events

Date Code Title Description
ST Notification of lapse