FR2362144A1 - Derives de la dihydrocodeinone, leur preparation et leur emploi dans la synthese de la codeine - Google Patents

Derives de la dihydrocodeinone, leur preparation et leur emploi dans la synthese de la codeine

Info

Publication number
FR2362144A1
FR2362144A1 FR7724867A FR7724867A FR2362144A1 FR 2362144 A1 FR2362144 A1 FR 2362144A1 FR 7724867 A FR7724867 A FR 7724867A FR 7724867 A FR7724867 A FR 7724867A FR 2362144 A1 FR2362144 A1 FR 2362144A1
Authority
FR
France
Prior art keywords
dihydrocodeinone
derivatives
codeine
synthesis
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7724867A
Other languages
English (en)
Other versions
FR2362144B1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Macfarlan Smith Ltd
Original Assignee
Macfarlan Smith Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Macfarlan Smith Ltd filed Critical Macfarlan Smith Ltd
Publication of FR2362144A1 publication Critical patent/FR2362144A1/fr
Application granted granted Critical
Publication of FR2362144B1 publication Critical patent/FR2362144B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D489/00—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula:
    • C07D489/02—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula: with oxygen atoms attached in positions 3 and 6, e.g. morphine, morphinone
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D489/00—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula:
    • C07D489/02—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula: with oxygen atoms attached in positions 3 and 6, e.g. morphine, morphinone
    • C07D489/04—Salts; Organic complexes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

L'invention est relative à des nouveaux dérivés de la dihydrocodéinone. Les composés selon l'invention répondent à la formule générale suivante :
FR7724867A 1976-08-17 1977-08-12 Derives de la dihydrocodeinone, leur preparation et leur emploi dans la synthese de la codeine Granted FR2362144A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB34195/76A GB1582234A (en) 1976-08-17 1976-08-17 Morphine derivatives

Publications (2)

Publication Number Publication Date
FR2362144A1 true FR2362144A1 (fr) 1978-03-17
FR2362144B1 FR2362144B1 (fr) 1983-01-28

Family

ID=10362573

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7724867A Granted FR2362144A1 (fr) 1976-08-17 1977-08-12 Derives de la dihydrocodeinone, leur preparation et leur emploi dans la synthese de la codeine

Country Status (14)

Country Link
US (1) US4140687A (fr)
JP (1) JPS5323998A (fr)
AU (1) AU517187B2 (fr)
BE (1) BE857753A (fr)
CA (1) CA1085834A (fr)
DE (1) DE2736260A1 (fr)
FR (1) FR2362144A1 (fr)
GB (1) GB1582234A (fr)
HU (1) HU176841B (fr)
IL (1) IL52632A (fr)
NL (1) NL7709024A (fr)
NO (1) NO772852L (fr)
PL (1) PL104043B1 (fr)
YU (1) YU40008B (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2007015789A (es) * 2005-06-16 2008-02-15 Mallinckrodt Inc Nueva ruta de sintesis para opiatos de 14-hidroxilo a traves de 1-halo-tebaina o analogos.

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2778832A (en) * 1954-06-22 1957-01-22 Merck & Co Inc Reduction of codeinone to codeine
FR1282642A (fr) * 1960-12-13 1962-01-27 S E M P A Préparation de la codéine et de composés apparentés
GB937128A (en) * 1961-01-25 1963-09-18 Sempa Chimie Method for the preparation of codeinone from thebaine
FR2342288A1 (fr) * 1976-02-26 1977-09-23 Quimicos Farma Fab Prod Procede pour la preparation de codeinone a partir de thebaine

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3112323A (en) * 1963-11-26 Method for the preparation of
US4054566A (en) * 1976-03-10 1977-10-18 The Regents Of The University Of California Process for converting neopinone to codeinone
US4052402A (en) * 1976-03-15 1977-10-04 Fabrica De Productos Quimicos Y Farmaceuticos Abello, S.A. Process for synthesizing codeinone from thebaine

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2778832A (en) * 1954-06-22 1957-01-22 Merck & Co Inc Reduction of codeinone to codeine
FR1282642A (fr) * 1960-12-13 1962-01-27 S E M P A Préparation de la codéine et de composés apparentés
GB937128A (en) * 1961-01-25 1963-09-18 Sempa Chimie Method for the preparation of codeinone from thebaine
FR2342288A1 (fr) * 1976-02-26 1977-09-23 Quimicos Farma Fab Prod Procede pour la preparation de codeinone a partir de thebaine

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
CA1977 *
EXBK/76 *

Also Published As

Publication number Publication date
PL104043B1 (pl) 1979-07-31
IL52632A (en) 1980-02-29
NL7709024A (nl) 1978-02-21
DE2736260A1 (de) 1978-02-23
AU517187B2 (en) 1981-07-16
IL52632A0 (en) 1977-10-31
HU176841B (en) 1981-05-28
YU40008B (en) 1985-06-30
GB1582234A (en) 1981-01-07
NO772852L (no) 1978-02-20
AU2754977A (en) 1979-02-08
JPS6312872B2 (fr) 1988-03-23
YU194877A (en) 1983-01-21
BE857753A (fr) 1978-02-13
FR2362144B1 (fr) 1983-01-28
PL200323A1 (pl) 1978-05-08
JPS5323998A (en) 1978-03-06
CA1085834A (fr) 1980-09-16
US4140687A (en) 1979-02-20

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