FR2358892A1 - N(1'-allyl 2'-pyrrolidylmethyl)2,3-dimethoxy 5-sulfamoyl benzamide, ses derives - Google Patents
N(1'-allyl 2'-pyrrolidylmethyl)2,3-dimethoxy 5-sulfamoyl benzamide, ses derivesInfo
- Publication number
- FR2358892A1 FR2358892A1 FR7622180A FR7622180A FR2358892A1 FR 2358892 A1 FR2358892 A1 FR 2358892A1 FR 7622180 A FR7622180 A FR 7622180A FR 7622180 A FR7622180 A FR 7622180A FR 2358892 A1 FR2358892 A1 FR 2358892A1
- Authority
- FR
- France
- Prior art keywords
- benzamide
- pyrrolidylmethyl
- dimethoxy
- allyl
- derivatives
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/08—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
- C07D207/09—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Neurology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyrrole Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Priority Applications (40)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7622180A FR2358892A1 (fr) | 1976-07-19 | 1976-07-19 | N(1'-allyl 2'-pyrrolidylmethyl)2,3-dimethoxy 5-sulfamoyl benzamide, ses derives |
| CY1036A CY1036A (en) | 1976-07-19 | 1977-05-24 | N-(1'-allyl-2'-pyrrolidylmethyl)-2,3-dimethoxy-5-sulphamoyolbenzamide and derivatives |
| GB21883/77A GB1539319A (en) | 1976-07-19 | 1977-05-24 | N-(1'-allyl-2'-pyrrolidylmethyl)-2,3-dimethoxy-5-sulphamoylbenzamide and derivatives |
| BE1008238A BE856289A (fr) | 1976-07-19 | 1977-06-30 | N-(1'-allyle-2'-pyrrolidylmethyl)2,3-dimethoxy 5-sulfamoyl benzamide, ses derives |
| OA56219A OA05704A (fr) | 1976-07-19 | 1977-07-05 | Procédé de préparation de N (l'-allyl 2'-pyrrolidylméthyl) 2,3-diméthoxy 5-sulfamoyl benzamide. |
| MC771249A MC1153A1 (fr) | 1976-07-19 | 1977-07-05 | N-(1'-allyl 2'-pyrrolidylmethyl)2,3-dimethoxy 5-sulfamoyl benzamide,ses derives |
| ZM54/77A ZM5477A1 (en) | 1976-07-19 | 1977-07-08 | N(1'-allyl 2'-pyrrolidylmethyl) 2,3-dimethoxy 5-sulfamoyl benzamide, its derivatives |
| PH19975A PH12838A (en) | 1976-07-19 | 1977-07-08 | N-(1'-allyl 2'-pyrrolidylmethyl)2,3-dimet 5-sulfamoyl benzamide,it's derivatives |
| AR268387A AR214330A1 (es) | 1976-07-19 | 1977-07-11 | Procedimiento para la preparacion de n-(1'-alil-2'-pirrolidilmetil)-2,3-dimetoxi-5-sulfamoilbenzamida |
| EG413/77A EG12911A (en) | 1976-07-19 | 1977-07-11 | Process for preparing of n(1-allyl 2-pynolidy-methyl)2,3-dimethoxy 5-sulfamaylbenzamide its derivatives |
| ES460621A ES460621A1 (es) | 1976-07-19 | 1977-07-11 | Procedimiento de sintesis de n-(1'-alil-2'-pirrolidilmetil)-2,3-dimetoxi-5-sulfamoilbenzamida. |
| GR53944A GR60836B (en) | 1976-07-19 | 1977-07-12 | Preparation process of n-(i-alkyl-2'-pyrrolidylmethyl)-2,3-dimethoxy-5-sulphamoylbenzamide and derivatives thereof |
| YU1739/77A YU40677B (en) | 1976-07-19 | 1977-07-13 | Process for obtaininga n-(1'allyl-2'-pyrrolidylmethyl)-2,3-dimethoxy-5-sulfamoyl benzamides |
| NZ184634A NZ184634A (en) | 1976-07-19 | 1977-07-13 | N-(i'allyl-2-pyrrolidylmethyl)-2,3-dimethoxy-5-sulphamoyl-benzamide and pharmaceutical compositions |
| CH867977A CH627162A5 (US07696358-20100413-C00002.png) | 1976-07-19 | 1977-07-13 | |
| AU27026/77A AU509291B2 (en) | 1976-07-19 | 1977-07-14 | N-(1'-allyl 2'-pyrrolidylmethyl1) 2,3-dimethoxy 5-sulfamoylbenzamide derivatives |
| SE7708176A SE425243B (sv) | 1976-07-19 | 1977-07-14 | Forfarande for framstellning av n-(1'-alkyl-2'-pyrrolidylmetyl)-2,3-dimetoxi-5-sulfamoylbensamid med terapeutisk verkan |
| NO772530A NO146598C (no) | 1976-07-19 | 1977-07-15 | Analogifremgangsmaate for fremstilling av det terapeutisk aktive n-(1`-allyl-2`-pyrrolidylmetyl)-2,3-dimetoksy-5-sulfamoylbenzamider og derivater derav |
| DD7700200091A DD132492A5 (de) | 1976-07-19 | 1977-07-15 | Verfahren zur herstellung von n-(1-allyl-2'-pyrrolidylmethyl)-2,3-dimethoxy-5-sulfamoylbenzamid und seinen derivaten |
| JP8552977A JPS5338631A (en) | 1976-07-19 | 1977-07-15 | Treating composition for nerve and sympathetic nerve disease group |
| AT0511677A AT365570B (de) | 1976-07-19 | 1977-07-15 | Verfahren zur herstellung des neuen n-(1'-allyl-2'-pyrrolidinylmethyl)-2,3-dimethox -5-sulfamoyl- benzamid, seinen saeureadditionssalzen, quartaeren ammoniumsalzen, seinem n-oxid sowie seinen opti- schen antipoden |
| HU77SO1193A HU174981B (hu) | 1976-07-19 | 1977-07-15 | Sposob poluchenija n-skobka-1-allil-2-pirrolidilmetil-skobka zakryta-2,3-dimetoksi-5-sul'famoil-benzamida i farmacevticheskikh kompozicijj soderzhahhikh ikh aktivnymi agentami |
| DD77207969A DD137670A5 (de) | 1976-07-19 | 1977-07-15 | Verfahren zur herstellung einer neuen pharmazeutischen zusammensetzung |
| MX775905U MX4711E (es) | 1976-07-19 | 1977-07-15 | Procedimiento para preparar derivados-be-n-(1-alil-2-pirrolidilmetil)-2-3-dimetoxi-5-sulfamoilbenzamida |
| LU77782A LU77782A1 (US07696358-20100413-C00002.png) | 1976-07-19 | 1977-07-15 | |
| IE1482/77A IE46171B1 (en) | 1976-07-19 | 1977-07-15 | N-(1'-allyl-2'-pyrrolidylmethyl)-2,3-dimethoxy-5-sulphamoylbenzamide and derivatives |
| PT66819A PT66819B (fr) | 1976-07-19 | 1977-07-15 | Procede de preparation de n-(1'-allyl 2'-pyrrolidylmethyl)2,3-dimethoxy 5-sulfamoyl benzamida et ses derives |
| NLAANVRAGE7707982,A NL174347C (nl) | 1976-07-19 | 1977-07-18 | Werkwijze voor het bereiden van een farmaceutisch preparaat dat een (alkoxy-benzamide)-pyrrolidine bevat alsmede van een benzamidederivaat. |
| IL52547A IL52547A (en) | 1976-07-19 | 1977-07-18 | N-(1'-allyl-2'-pyrrolidylmethyl)-2,3-dimethoxy-5-sulphamoylbenzamide its optical isomers its n-oxide and pharmaceutically acceptable salts thereof their preparation and pharmaceutical compoistions containing them |
| FI772214A FI67213C (fi) | 1976-07-19 | 1977-07-18 | Foerfarande foer framstaellning av terapeutiskt anvaendbar n-(1'-allyl-2'-pyrrolidylmetyl)-2,3-dimetoxi-5-sulfamoylbensamid |
| PL1977199723A PL104244B1 (pl) | 1976-07-19 | 1977-07-18 | Sposob wytwarzania n/1'-alkilo-2'-metylopirolidylo/-2,3-dwumetoksy-5-sulfamylobenzamidu i jego pochodnych |
| DK326377A DK156646C (da) | 1976-07-19 | 1977-07-18 | Analogifremgangsmaade til fremstilling af n-(1'-allyl-2'-pyrrolidylmethyl)-2,3-dimethoxy-5-sulfamoyl-benzamid eller syreadditionssalte, kvaternaere ammoniumsalte, n-oxider eller optisk aktive isomere deraf |
| RO7791091A RO71691A (ro) | 1976-07-19 | 1977-07-19 | Procedeu pentru prepararea n-(1-alil-2-pirolidilmctil)-2,3-dimetoxi-5-sulfamoilbenzamidei |
| SU772504152A SU695556A3 (ru) | 1976-07-19 | 1977-07-19 | Способ получени -/1-аллил-2пирролидилметил/-2,3-диметокси-5сульфамоилбензамида или его солей |
| CS774811A CS219885B2 (en) | 1976-07-19 | 1977-07-19 | Method of making the n-lallyl-2-pyrolidylmethyl/-2,3-dimethoxy-5-sulphamoylbenzamide |
| IN1318/CAL/77A IN146993B (US07696358-20100413-C00002.png) | 1976-07-19 | 1977-08-23 | |
| ZA00774256A ZA774256B (en) | 1976-07-19 | 1978-05-12 | N(1'-allyl 2'-pyrrolidylmethyl)2,3-dimethoxy 5-sulfamoyl benzamide,its derivatives |
| IN457/CAL/79A IN148039B (US07696358-20100413-C00002.png) | 1976-07-19 | 1979-05-04 | |
| HK178/80A HK17880A (en) | 1976-07-19 | 1980-04-03 | N-(1'-allyl-2'-pyrrolidylmethyl)-2-3-dimethoxy-5-sulphamoylbenzamide and derivatives |
| US06/540,918 US4499019A (en) | 1976-07-19 | 1983-10-13 | N-(1-allyl-2-pyrrolidylmethyl)-2,3-dimethoxy-5-sulfamoylbenzamide and derivatives thereof and method for treating hot flushes associated with natural or surgical menopause |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7622180A FR2358892A1 (fr) | 1976-07-19 | 1976-07-19 | N(1'-allyl 2'-pyrrolidylmethyl)2,3-dimethoxy 5-sulfamoyl benzamide, ses derives |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FR2358892A1 true FR2358892A1 (fr) | 1978-02-17 |
| FR2358892B1 FR2358892B1 (US07696358-20100413-C00002.png) | 1978-12-15 |
Family
ID=9175947
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR7622180A Granted FR2358892A1 (fr) | 1976-07-19 | 1976-07-19 | N(1'-allyl 2'-pyrrolidylmethyl)2,3-dimethoxy 5-sulfamoyl benzamide, ses derives |
Country Status (38)
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2438650A1 (fr) * | 1978-10-11 | 1980-05-09 | Ile De France | N-(1-methyl 2-pyrrolidinyl methyl) 2,3-dimethoxy 5-methylsulfamoyl benzamide et ses derives, leurs methodes de preparation et leur application dans le traitement des troubles du bas appareil urinaire |
| FR2478093A1 (fr) * | 1980-03-12 | 1981-09-18 | Ile De France | Nouveau procede de preparation de n-(1-alkyl (ou allyl) 2-pyrrolidinyl-methyl)2-methoxy (ou 2,3-dimethoxy) 5-sulfamoyl (ou sulfamoyl substitue) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5639431A (en) * | 1979-09-06 | 1981-04-15 | Susumu Yagyu | Colorimeter having two-light pass length and two-wave length |
| FR2550447B1 (fr) * | 1983-08-10 | 1986-01-17 | Ile De France | Application du n-(ally-2-pyrrolidinylmethyl) 2-methoxy 4-amino 5-methylsulfamoyl benzamide comme antiagregant plaquettaire |
| FR2584605B1 (fr) * | 1985-07-15 | 1988-06-17 | Ile De France | Application du n-(1-allyl-2-pyrrolidinylmethyl) 2-methoxy 4-amino 5-methylsulfamoyl benzamide dans le traitement de la maladie de parkinson |
| US7645750B2 (en) * | 2006-12-13 | 2010-01-12 | Yung Shin Pharmaceutical Ind. Co., Ltd. | Method of treating symptoms of hormonal variations |
| US8420624B2 (en) * | 2007-12-04 | 2013-04-16 | Yung Shin Pharm. Ind. Co., Ltd. | Methods for treating or preventing symptoms of hormonal variations |
| CN105481733A (zh) * | 2015-12-30 | 2016-04-13 | 苏州诚和医药化学有限公司 | 一种一步法合成2-甲氧基-5-氨磺酰基苯甲酸甲酯的方法 |
-
1976
- 1976-07-19 FR FR7622180A patent/FR2358892A1/fr active Granted
-
1977
- 1977-05-24 CY CY1036A patent/CY1036A/xx unknown
- 1977-05-24 GB GB21883/77A patent/GB1539319A/en not_active Expired
- 1977-06-30 BE BE1008238A patent/BE856289A/xx not_active IP Right Cessation
- 1977-07-05 OA OA56219A patent/OA05704A/xx unknown
- 1977-07-05 MC MC771249A patent/MC1153A1/xx unknown
- 1977-07-08 PH PH19975A patent/PH12838A/en unknown
- 1977-07-08 ZM ZM54/77A patent/ZM5477A1/xx unknown
- 1977-07-11 AR AR268387A patent/AR214330A1/es active
- 1977-07-11 EG EG413/77A patent/EG12911A/xx active
- 1977-07-11 ES ES460621A patent/ES460621A1/es not_active Expired
- 1977-07-12 GR GR53944A patent/GR60836B/el unknown
- 1977-07-13 CH CH867977A patent/CH627162A5/fr not_active IP Right Cessation
- 1977-07-13 YU YU1739/77A patent/YU40677B/xx unknown
- 1977-07-13 NZ NZ184634A patent/NZ184634A/xx unknown
- 1977-07-14 SE SE7708176A patent/SE425243B/xx not_active IP Right Cessation
- 1977-07-14 AU AU27026/77A patent/AU509291B2/en not_active Expired
- 1977-07-15 PT PT66819A patent/PT66819B/pt unknown
- 1977-07-15 AT AT0511677A patent/AT365570B/de not_active IP Right Cessation
- 1977-07-15 LU LU77782A patent/LU77782A1/xx unknown
- 1977-07-15 DD DD77207969A patent/DD137670A5/xx not_active IP Right Cessation
- 1977-07-15 MX MX775905U patent/MX4711E/es unknown
- 1977-07-15 JP JP8552977A patent/JPS5338631A/ja active Granted
- 1977-07-15 DD DD7700200091A patent/DD132492A5/xx not_active IP Right Cessation
- 1977-07-15 NO NO772530A patent/NO146598C/no unknown
- 1977-07-15 HU HU77SO1193A patent/HU174981B/hu unknown
- 1977-07-15 IE IE1482/77A patent/IE46171B1/en not_active IP Right Cessation
- 1977-07-18 NL NLAANVRAGE7707982,A patent/NL174347C/xx not_active IP Right Cessation
- 1977-07-18 IL IL52547A patent/IL52547A/xx unknown
- 1977-07-18 FI FI772214A patent/FI67213C/fi not_active IP Right Cessation
- 1977-07-18 DK DK326377A patent/DK156646C/da not_active IP Right Cessation
- 1977-07-18 PL PL1977199723A patent/PL104244B1/pl unknown
- 1977-07-19 SU SU772504152A patent/SU695556A3/ru active
- 1977-07-19 CS CS774811A patent/CS219885B2/cs unknown
- 1977-07-19 RO RO7791091A patent/RO71691A/ro unknown
- 1977-08-23 IN IN1318/CAL/77A patent/IN146993B/en unknown
-
1978
- 1978-05-12 ZA ZA00774256A patent/ZA774256B/xx unknown
-
1980
- 1980-04-03 HK HK178/80A patent/HK17880A/xx unknown
-
1983
- 1983-10-13 US US06/540,918 patent/US4499019A/en not_active Expired - Lifetime
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2438650A1 (fr) * | 1978-10-11 | 1980-05-09 | Ile De France | N-(1-methyl 2-pyrrolidinyl methyl) 2,3-dimethoxy 5-methylsulfamoyl benzamide et ses derives, leurs methodes de preparation et leur application dans le traitement des troubles du bas appareil urinaire |
| FR2478093A1 (fr) * | 1980-03-12 | 1981-09-18 | Ile De France | Nouveau procede de preparation de n-(1-alkyl (ou allyl) 2-pyrrolidinyl-methyl)2-methoxy (ou 2,3-dimethoxy) 5-sulfamoyl (ou sulfamoyl substitue) |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| CL | Concession to grant licences | ||
| CL | Concession to grant licences | ||
| CC | Supplementary protection certificate (spc) laid open to the public (law of 25 june 1990) |
Free format text: 92C0158, 920505 |
|
| CB | Supplementary protection certificate (spc) granted (law of 25 june 1990) |
Free format text: 92C0158, 760719 |
|
| CL | Concession to grant licences | ||
| TP | Transmission of property |