FR2355510A1 - Procede de production de compositions pharmaceutiques renfermant un melange de solution aqueuse de polymere carboxyvinylique avec un compose basique - Google Patents

Procede de production de compositions pharmaceutiques renfermant un melange de solution aqueuse de polymere carboxyvinylique avec un compose basique

Info

Publication number
FR2355510A1
FR2355510A1 FR7718796A FR7718796A FR2355510A1 FR 2355510 A1 FR2355510 A1 FR 2355510A1 FR 7718796 A FR7718796 A FR 7718796A FR 7718796 A FR7718796 A FR 7718796A FR 2355510 A1 FR2355510 A1 FR 2355510A1
Authority
FR
France
Prior art keywords
mixture
production
aqueous solution
carboxyvinyl polymer
pharmaceutical compositions
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7718796A
Other languages
English (en)
Other versions
FR2355510B1 (fr
Inventor
Takuzo Kamishita
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Toko Yakuhin Kogyo KK
Original Assignee
Toko Yakuhin Kogyo KK
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Toko Yakuhin Kogyo KK filed Critical Toko Yakuhin Kogyo KK
Publication of FR2355510A1 publication Critical patent/FR2355510A1/fr
Application granted granted Critical
Publication of FR2355510B1 publication Critical patent/FR2355510B1/fr
Granted legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0031—Rectum, anus

Abstract

Procédé de production de compositions pharmaceutiques à insertion et nouveaux produits ainsi obtenus. Ces compositions comprennent un mélange d'une solution aqueuse de polymère carboxyvinylique avec un composé basique soluble dans l'eau et un ingrédient pharmaceutique, le melange étant un gel ayant une valeur de pH de 4 à 10 et une viscosité de 5 000 à 100 000 centipoises à 20 degrés C. La présente invention est particulièrement utile pour fournir des compositions qui sont appliquées aux tissus du rectum, du vagin ou de l'urètre, l'ingrédient pharmaceutique étant absorbé dans le courant sanguin de l'organisme humain.
FR7718796A 1976-06-21 1977-06-20 Procede de production de compositions pharmaceutiques renfermant un melange de solution aqueuse de polymere carboxyvinylique avec un compose basique Granted FR2355510A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP7296076A JPS52156913A (en) 1976-06-21 1976-06-21 Production of injectionable medicine

Publications (2)

Publication Number Publication Date
FR2355510A1 true FR2355510A1 (fr) 1978-01-20
FR2355510B1 FR2355510B1 (fr) 1981-12-11

Family

ID=13504445

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7718796A Granted FR2355510A1 (fr) 1976-06-21 1977-06-20 Procede de production de compositions pharmaceutiques renfermant un melange de solution aqueuse de polymere carboxyvinylique avec un compose basique

Country Status (11)

Country Link
US (1) US4472376A (fr)
JP (1) JPS52156913A (fr)
AT (1) AT360654B (fr)
BE (1) BE855780A (fr)
CH (1) CH638402A5 (fr)
DE (1) DE2727913A1 (fr)
DK (1) DK271677A (fr)
ES (1) ES459938A1 (fr)
FR (1) FR2355510A1 (fr)
GB (1) GB1552521A (fr)
NL (1) NL189548C (fr)

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0068552A2 (fr) * 1981-06-23 1983-01-05 THE PROCTER & GAMBLE COMPANY Composition topique antimicrobienne
EP0101178A3 (en) * 1982-07-13 1985-05-22 Pfizer Corporation Topical anti-inflammatory compositions
EP0265400A2 (fr) * 1986-08-18 1988-04-27 Ferring AB Gel topique radio protectif pour muqueuses
EP0386688A1 (fr) * 1989-03-08 1990-09-12 Hoechst Japan Limited Méthode de préparation d'hydrogels et de xérogels
FR2668705A1 (fr) * 1990-11-06 1992-05-07 Bouchara Sa Nouvelles preparations dermiques a action phlebotonique et leur procede de preparation.
WO1993002662A1 (fr) * 1991-07-26 1993-02-18 L.C. Pharchem Ltd. Compositions pharmaceutiques antivirales administrees par voie vaginale
WO1997012618A1 (fr) * 1995-10-05 1997-04-10 Laboratoire Innothera, Societe Anonyme Gel pour hormonotherapie locale de la secheresse vaginale
EP0711560B1 (fr) * 1994-11-08 2001-06-27 Adir Et Compagnie Composition pharmaceutique pour l'administration orale de flavonoides

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6042766B2 (ja) 1978-12-09 1985-09-25 日本化薬株式会社 基剤
CH643138A5 (de) * 1983-08-29 1984-05-30 Mepha Ag Indomethacin enthaltende, gelartige salbe.
DE3686275T2 (de) * 1985-01-11 1993-03-18 Teijin Ltd Praeparate mit verzoegerter freisetzung.
IT1213323B (it) * 1986-08-07 1989-12-20 Crinos Industria Farmaco Composizione per uso locale ad atti vita' spermicida virulicida ,disinfettante e/o battericida
US5071643A (en) * 1986-10-17 1991-12-10 R. P. Scherer Corporation Solvent system enhancing the solubility of pharmaceuticals for encapsulation
US5536743A (en) * 1988-01-15 1996-07-16 Curatek Pharmaceuticals Limited Partnership Intravaginal treatment of vaginal infections with buffered metronidazole compositions
US5002938A (en) * 1988-03-21 1991-03-26 Bristol-Myers Squibb Company Antifungal gel formulations
US5110809A (en) * 1988-03-21 1992-05-05 Bristol-Myers Squibb Company Antifungal gel formulations
SE463851B (sv) * 1988-09-02 1991-02-04 Amsu Ltd Komposition foer behandling av erektil dysfunktion via uretra
US4863792A (en) * 1988-10-14 1989-09-05 Minnesota Mining And Manufacturing Company Multi-layer laminates of microporous films
US5256737A (en) * 1990-03-05 1993-10-26 Sigma Prodotti Chimici S.P.A. Thickening agents, processes for the preparation thereof and use thereof
US5242391A (en) * 1990-04-25 1993-09-07 Alza Corporation Urethral insert for treatment of erectile dysfunction
US5466680A (en) * 1992-03-26 1995-11-14 Cytologics, Inc. Method and compositions for enhancing white blood cell functioning on a mucosal or cutaneous surface
BR9203277A (pt) * 1992-08-21 1994-03-01 Cesar Roberto Dias Nahoum Utilizaccao de drogas eretogenicas e respectivas metodologias de aplicacao
US5773457A (en) * 1995-02-15 1998-06-30 Cesar Roberto Dias Nahoum Compositions
GB9422571D0 (en) * 1994-11-09 1995-01-04 Whitehall Lab Ltd Haemorrihoidal compositions and method of use
US5807568A (en) * 1994-12-27 1998-09-15 Mcneil-Ppc, Inc. Enhanced delivery of topical compositions containing flurbiprofen
SE9602644D0 (sv) * 1996-07-04 1996-07-04 Astra Ab New use
US6486207B2 (en) 1998-12-10 2002-11-26 Nexmed (Holdings), Inc. Compositions and methods for amelioration of human female sexual dysfunction
US20070191320A1 (en) * 1998-12-10 2007-08-16 Nexmed Holdings, Inc. Methods of treatment for female sexual arousal disorder
US6825234B2 (en) 1998-12-10 2004-11-30 Nexmed (Holdings) , Inc. Compositions and methods for amelioration of human female sexual dysfunction
US20050180985A9 (en) * 2001-10-04 2005-08-18 Vladoianu Ion R. Live attenuated salmonella strains for producing monovalent or multivalent vaccines
DE10227232A1 (de) * 2002-06-18 2004-01-15 Aventis Pharma Deutschland Gmbh Saure Insulinzubereitungen mit verbesserter Stabilität
US7371399B2 (en) * 2004-07-23 2008-05-13 Prescott Albert G Polymer gel containing hyaluronic acid and collagen, and its use in joints
US20060093675A1 (en) * 2004-10-29 2006-05-04 Mathew Ebmeier Intravaginal treatment of vaginal infections with metronidazole compositions
DE102004062468A1 (de) * 2004-12-20 2006-06-29 Manuela Glaschak Zusammensetzung zur vaginalen Anwendung
US8637096B2 (en) 2009-12-04 2014-01-28 Curtis C. Stojan Compositions and method for enhancing insulin activity
US20110135681A1 (en) * 2009-12-04 2011-06-09 Stojan Curtis C Composition and Method for Enhancing Insulin Activity
GB201010954D0 (en) 2010-06-29 2010-08-11 Edko Pazarlama Tanitim Ticaret Compositions
ES2395801B1 (es) * 2011-06-23 2014-06-06 María Carmen PARDINA PALLEJÀ "pentoxifilina por vía transvaginal para el tratamiento de la infertilidad"

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE735177C (de) * 1941-05-04 1943-05-11 Ig Farbenindustrie Ag Grundlage fuer Zitzenstifte
DE751427C (de) * 1942-11-15 1953-01-19 Ig Farbenindustrie Ag Grundlage fuer Zitzenstifte
US2823163A (en) * 1956-10-11 1958-02-11 Richard K Thoms Antivaginitis process and cation exchange resin composition
GB1023895A (en) * 1964-06-03 1966-03-30 Plough Alcoholic compositions
GB1135966A (en) * 1966-01-06 1968-12-11 Ceskoslovenska Akademie Ved Improvements in or relating to sustained-release medicaments
FR2139825A1 (fr) * 1971-04-15 1973-01-12 Meiji Seika Kaisha
LU70487A1 (fr) * 1974-07-08 1976-05-31

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH476499A (de) * 1964-12-31 1969-08-15 Ciba Geigy Mischung zum Überziehen von Rektal-Kapseln
DK135267A (fr) * 1971-02-25
DE3106620A1 (de) * 1981-02-23 1982-09-02 Klaus-Dieter Dr. 3550 Marburg Bremecker Pharmazeutische zubereitung in form eines mikroklysmas

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE735177C (de) * 1941-05-04 1943-05-11 Ig Farbenindustrie Ag Grundlage fuer Zitzenstifte
DE751427C (de) * 1942-11-15 1953-01-19 Ig Farbenindustrie Ag Grundlage fuer Zitzenstifte
US2823163A (en) * 1956-10-11 1958-02-11 Richard K Thoms Antivaginitis process and cation exchange resin composition
GB1023895A (en) * 1964-06-03 1966-03-30 Plough Alcoholic compositions
GB1135966A (en) * 1966-01-06 1968-12-11 Ceskoslovenska Akademie Ved Improvements in or relating to sustained-release medicaments
FR2139825A1 (fr) * 1971-04-15 1973-01-12 Meiji Seika Kaisha
LU70487A1 (fr) * 1974-07-08 1976-05-31

Cited By (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0068552A2 (fr) * 1981-06-23 1983-01-05 THE PROCTER & GAMBLE COMPANY Composition topique antimicrobienne
EP0068552A3 (fr) * 1981-06-23 1984-03-28 THE PROCTER & GAMBLE COMPANY Composition topique antimicrobienne
EP0101178A3 (en) * 1982-07-13 1985-05-22 Pfizer Corporation Topical anti-inflammatory compositions
US4678666A (en) * 1982-07-13 1987-07-07 Pfizer Inc. Topical anti-inflammatory compositions
EP0265400A2 (fr) * 1986-08-18 1988-04-27 Ferring AB Gel topique radio protectif pour muqueuses
EP0265400A3 (en) * 1986-08-18 1988-11-09 Ferring Ab Topical radioprotective gel for mucosa
EP0386688A1 (fr) * 1989-03-08 1990-09-12 Hoechst Japan Limited Méthode de préparation d'hydrogels et de xérogels
FR2668705A1 (fr) * 1990-11-06 1992-05-07 Bouchara Sa Nouvelles preparations dermiques a action phlebotonique et leur procede de preparation.
WO1993002662A1 (fr) * 1991-07-26 1993-02-18 L.C. Pharchem Ltd. Compositions pharmaceutiques antivirales administrees par voie vaginale
EP0711560B1 (fr) * 1994-11-08 2001-06-27 Adir Et Compagnie Composition pharmaceutique pour l'administration orale de flavonoides
WO1997012618A1 (fr) * 1995-10-05 1997-04-10 Laboratoire Innothera, Societe Anonyme Gel pour hormonotherapie locale de la secheresse vaginale
FR2739559A1 (fr) * 1995-10-05 1997-04-11 Innothera Lab Sa Gel pour hormonotherapie locale de la secheresse vaginale

Also Published As

Publication number Publication date
CH638402A5 (de) 1983-09-30
NL189548B (nl) 1992-12-16
DK271677A (da) 1977-12-22
NL189548C (nl) 1993-05-17
AT360654B (de) 1981-01-26
JPS5538926B2 (fr) 1980-10-07
ES459938A1 (es) 1979-06-01
US4472376A (en) 1984-09-18
DE2727913A1 (de) 1977-12-29
FR2355510B1 (fr) 1981-12-11
JPS52156913A (en) 1977-12-27
DE2727913C2 (fr) 1987-12-03
NL7706301A (nl) 1977-12-23
ATA430677A (de) 1980-06-15
GB1552521A (en) 1979-09-12
BE855780A (nl) 1977-12-19

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