FR2340733A2 - Nouveaux derives de l'isoindoline, leur preparation et les compositions qui les contiennent - Google Patents
Nouveaux derives de l'isoindoline, leur preparation et les compositions qui les contiennentInfo
- Publication number
- FR2340733A2 FR2340733A2 FR7603773A FR7603773A FR2340733A2 FR 2340733 A2 FR2340733 A2 FR 2340733A2 FR 7603773 A FR7603773 A FR 7603773A FR 7603773 A FR7603773 A FR 7603773A FR 2340733 A2 FR2340733 A2 FR 2340733A2
- Authority
- FR
- France
- Prior art keywords
- pyrrolo
- substd
- tranquillisers
- epileptics
- hypnotics
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000001961 anticonvulsive agent Substances 0.000 title abstract 3
- FLBAYUMRQUHISI-UHFFFAOYSA-N 1,8-naphthyridine Chemical compound N1=CC=CC2=CC=CN=C21 FLBAYUMRQUHISI-UHFFFAOYSA-N 0.000 title abstract 2
- 230000003556 anti-epileptic effect Effects 0.000 title abstract 2
- 229960003965 antiepileptics Drugs 0.000 title abstract 2
- 239000003326 hypnotic agent Substances 0.000 title abstract 2
- 230000000147 hypnotic effect Effects 0.000 title abstract 2
- GWVMLCQWXVFZCN-UHFFFAOYSA-N isoindoline Chemical compound C1=CC=C2CNCC2=C1 GWVMLCQWXVFZCN-UHFFFAOYSA-N 0.000 title abstract 2
- DZTRFRMZYKJDEC-UHFFFAOYSA-N 6h-pyrrolo[3,4-b]pyridine Chemical compound N1=CC=CC2=CNC=C21 DZTRFRMZYKJDEC-UHFFFAOYSA-N 0.000 title 1
- HFDGGXUVSFYTLN-UHFFFAOYSA-N c1ncc2[nH]ccnc12 Chemical class c1ncc2[nH]ccnc12 HFDGGXUVSFYTLN-UHFFFAOYSA-N 0.000 title 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 3
- KAESVJOAVNADME-UHFFFAOYSA-N Pyrrole Chemical compound C=1C=CNC=1 KAESVJOAVNADME-UHFFFAOYSA-N 0.000 abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 125000005843 halogen group Chemical group 0.000 abstract 2
- 125000006569 (C5-C6) heterocyclic group Chemical group 0.000 abstract 1
- GSIQLKOFXMCKNK-UHFFFAOYSA-N 6,7-dihydro-5h-pyrrolo[3,4-b]pyrazine Chemical compound C1=CN=C2CNCC2=N1 GSIQLKOFXMCKNK-UHFFFAOYSA-N 0.000 abstract 1
- SJMNQXLXIIXDDS-UHFFFAOYSA-N 6,7-dihydro-5h-pyrrolo[3,4-b]pyridine Chemical compound C1=CC=C2CNCC2=N1 SJMNQXLXIIXDDS-UHFFFAOYSA-N 0.000 abstract 1
- RWRDLPDLKQPQOW-UHFFFAOYSA-N Pyrrolidine Chemical group C1CCNC1 RWRDLPDLKQPQOW-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 125000003342 alkenyl group Chemical group 0.000 abstract 1
- 125000004453 alkoxycarbonyl group Chemical group 0.000 abstract 1
- 125000003282 alkyl amino group Chemical group 0.000 abstract 1
- 125000000304 alkynyl group Chemical group 0.000 abstract 1
- 229940125681 anticonvulsant agent Drugs 0.000 abstract 1
- 125000004093 cyano group Chemical group *C#N 0.000 abstract 1
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 1
- 125000004356 hydroxy functional group Chemical group O* 0.000 abstract 1
- 229940035363 muscle relaxants Drugs 0.000 abstract 1
- 239000003158 myorelaxant agent Substances 0.000 abstract 1
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 1
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 1
- 125000004430 oxygen atom Chemical group O* 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 125000004434 sulfur atom Chemical group 0.000 abstract 1
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (48)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR7603773A FR2340733A2 (fr) | 1976-02-11 | 1976-02-11 | Nouveaux derives de l'isoindoline, leur preparation et les compositions qui les contiennent |
OA55782A OA05287A (fr) | 1975-04-07 | 1976-03-26 | Nouveaux composés hétérocycliques et leur préparation. |
NL7603307A NL7603307A (nl) | 1975-04-07 | 1976-03-30 | Nieuwe heterocyclische verbindingen, de bereiding ervan en preparaten die deze verbindingen bevat- ten. |
CS7600002084A CS186734B2 (en) | 1975-04-07 | 1976-03-31 | Method of producing derivatives of iso-indoline |
CS7700002623A CS186747B2 (en) | 1975-04-07 | 1976-03-31 | Method of producing novel derivatives of iso-indoline |
CS7700002624A CS186748B2 (en) | 1975-04-07 | 1976-03-31 | Method of producing novel derivatives of iso-indoline |
IL49344A IL49344A (en) | 1975-04-07 | 1976-04-05 | 2-substituted-7-halo-1,8-maphthyridine compounds,processesfor preparing the same and pharmaceutical compositions containing the same |
US05/673,868 US4086348A (en) | 1975-04-07 | 1976-04-05 | Naphthyridine derivatives |
CA249,577A CA1072957A (fr) | 1975-04-07 | 1976-04-05 | Composes heterocycliques, leur preparation et les compositions qui les contiennent |
DD192209A DD123605A5 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1975-04-07 | 1976-04-05 | |
PH18289A PH14015A (en) | 1975-04-07 | 1976-04-05 | Naphthyridinylisoindolinones and pharmaceucal compositions containing them |
AU12674/76A AU496349B2 (en) | 1976-04-05 | 1, 8-naphthyridine derivatives | |
CY1085A CY1085A (en) | 1975-04-07 | 1976-04-05 | 1,8-naphthyridine derivatives |
JP51038103A JPS51122094A (en) | 1975-04-07 | 1976-04-05 | Production of heterocyclic compound |
IE704/76A IE42973B1 (en) | 1975-04-07 | 1976-04-05 | 1,8-naphthyridine derivatives |
GB13703/76A GB1483996A (en) | 1975-04-07 | 1976-04-05 | 1,8-naphthyridine derivatives |
NO761168A NO144019C (no) | 1975-04-07 | 1976-04-06 | Analogifremgangsmaate for fremstilling av terapeutisk aktive naftyridinderivater |
SE7604044D SE7604044L (sv) | 1975-04-07 | 1976-04-06 | Forfarande for framstellning av nya heterocykliska foreningar |
SU762339152A SU648102A3 (ru) | 1975-04-07 | 1976-04-06 | Способ получени производных нафтиридинов или их солей |
CH1212178A CH614209A5 (en) | 1975-04-07 | 1976-04-06 | Process for the preparation of new heterocyclic compounds |
YU00869/76A YU86976A (en) | 1975-04-07 | 1976-04-06 | Process for obtaining new heterocyclic compounds |
DK162976A DK162976A (da) | 1975-04-07 | 1976-04-06 | Fremgangsmade til fremstilling af heterocycliske forbindelser |
CH430576A CH613453A5 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1975-04-07 | 1976-04-06 | |
SE7604044A SE421793B (sv) | 1975-04-07 | 1976-04-06 | Analogiforfarande for framstellning naftyridinsubstituerade pyrrolderivat |
LU74703A LU74703A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1975-04-07 | 1976-04-06 | |
MX14476U MX3138E (es) | 1975-04-07 | 1976-04-06 | Procedimiento para la preparacion de compuestos heterociclicos |
PT64976A PT64976B (fr) | 1975-04-07 | 1976-04-06 | Nouveaux composes heterocycliques leur preparation et les compositions qui les contiennent |
AT249776A AT348524B (de) | 1975-04-07 | 1976-04-07 | Verfahren zur herstellung von neuen naphthyridinderivaten und von deren saeureadditionssalzen |
PL1976202792A PL100988B1 (pl) | 1975-04-07 | 1976-04-07 | Sposob wytwarzania nowych pochodnych naftyrydynylo-piroliny |
HU76RO886A HU176315B (en) | 1975-04-07 | 1976-04-07 | Process for producing substituted aminocarbonyloxy-isoindolinone-, -pyrrolo-pyridine-, pyrrolo-pyrasine and oxathiino-pyrrole derivatives |
AR262814A AR214286A1 (es) | 1975-04-07 | 1976-04-07 | Procedimiento de preparacion de derivados de la 7-cloro-(naftiridina-1,8 il-2)1 oxo 2-aminocarboniloxi-5 pirrolina |
PL1976202791A PL100987B1 (pl) | 1975-04-07 | 1976-04-07 | Sposob wytwarzania nowych pochodnych naftyrydynylo-piroliny |
FI760937A FI60012C (fi) | 1975-04-07 | 1976-04-07 | Foerfarande foer framstaellning av terapeutiskt aktiva 2-(7-klor-1,8-naftyridin-2-yl)-3-(karbamoyloxi)isoindolin-1-oner |
DE19762615067 DE2615067A1 (de) | 1975-04-07 | 1976-04-07 | Neue heterocyclische verbindungen, deren herstellung und diese enthaltende zusammensetzungen |
PL1976188560A PL100184B1 (pl) | 1975-04-07 | 1976-04-07 | Sposob wytwarzania nowych pochodnych naftyrydynylo-piroliny |
ES446762A ES446762A1 (es) | 1975-04-07 | 1976-04-07 | Procedimiento de preparacion de un compuesto heterociclico. |
ES448848A ES448848A1 (es) | 1975-04-07 | 1976-06-14 | Procedimiento de preparacion de un compuesto heterociclico. |
ES448847A ES448847A1 (es) | 1975-04-07 | 1976-06-14 | Procedimiento de preparacion de un compuesto heterociclico. |
AR264893A AR213739A1 (es) | 1975-04-07 | 1976-09-28 | Procedimiento de preparacion de derivados de la(naftiridina-1,8 il-2)-1 oxo-2 aminocarboniloxi-5 pirrolina |
AR264924A AR214055A1 (es) | 1975-04-07 | 1976-09-30 | Procedimiento de preparacion de derivados de 7-cloro(naftiridina-1,8 il-2)-1 oxo-2 aminocarboniloxi-5 pirrolina |
SU772473622A SU637082A3 (ru) | 1975-04-07 | 1977-04-21 | Способ получени производных нафтиридинов |
SU772473623A SU638258A3 (ru) | 1975-04-07 | 1977-04-21 | Способ получени производных нафтиридинов |
US05/843,369 US4131674A (en) | 1975-04-07 | 1977-10-19 | Naphtyridine derivatives |
AT204778A AT348528B (de) | 1975-04-07 | 1978-03-22 | Verfahren zur herstellung von neuen naphthyridinderivaten |
AT204878A AT348529B (de) | 1975-04-07 | 1978-03-22 | Verfahren zur herstellung von neuen naphthyridinderivaten |
HK545/80A HK54580A (en) | 1975-04-07 | 1980-09-25 | 1,8-naphthyridine derivatives |
YU01304/82A YU130482A (en) | 1975-04-07 | 1982-06-15 | Process for obtaining new heterocyclic compounds |
YU01305/82A YU130582A (en) | 1975-04-07 | 1982-06-15 | Process for obtaining new heterocyclic compounds |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR7603773A FR2340733A2 (fr) | 1976-02-11 | 1976-02-11 | Nouveaux derives de l'isoindoline, leur preparation et les compositions qui les contiennent |
Publications (2)
Publication Number | Publication Date |
---|---|
FR2340733A2 true FR2340733A2 (fr) | 1977-09-09 |
FR2340733B2 FR2340733B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1978-11-10 |
Family
ID=9168998
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR7603773A Granted FR2340733A2 (fr) | 1975-04-07 | 1976-02-11 | Nouveaux derives de l'isoindoline, leur preparation et les compositions qui les contiennent |
Country Status (1)
Country | Link |
---|---|
FR (1) | FR2340733A2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) |
-
1976
- 1976-02-11 FR FR7603773A patent/FR2340733A2/fr active Granted
Also Published As
Publication number | Publication date |
---|---|
FR2340733B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1978-11-10 |
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