FR2318633A1 - Procede de preparation de derives de la quinoleine - Google Patents
Procede de preparation de derives de la quinoleineInfo
- Publication number
- FR2318633A1 FR2318633A1 FR7622494A FR7622494A FR2318633A1 FR 2318633 A1 FR2318633 A1 FR 2318633A1 FR 7622494 A FR7622494 A FR 7622494A FR 7622494 A FR7622494 A FR 7622494A FR 2318633 A1 FR2318633 A1 FR 2318633A1
- Authority
- FR
- France
- Prior art keywords
- alkyl
- alkoxy
- nitro
- cycloalkyl
- proviso
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- XNMYNYSCEJBRPZ-UHFFFAOYSA-N 2-[(3-butyl-1-isoquinolinyl)oxy]-N,N-dimethylethanamine Chemical class C1=CC=C2C(OCCN(C)C)=NC(CCCC)=CC2=C1 XNMYNYSCEJBRPZ-UHFFFAOYSA-N 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 7
- 125000003545 alkoxy group Chemical group 0.000 abstract 5
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 3
- UXTZUUVTGMDXNG-UHFFFAOYSA-N 1,2-benzoxazine-3,4-dione Chemical compound C1=CC=C2C(=O)C(=O)NOC2=C1 UXTZUUVTGMDXNG-UHFFFAOYSA-N 0.000 abstract 2
- NTYJJOPFIAHURM-UHFFFAOYSA-N Histamine Chemical compound NCCC1=CN=CN1 NTYJJOPFIAHURM-UHFFFAOYSA-N 0.000 abstract 2
- SMWDFEZZVXVKRB-UHFFFAOYSA-N Quinoline Chemical compound N1=CC=CC2=CC=CC=C21 SMWDFEZZVXVKRB-UHFFFAOYSA-N 0.000 abstract 2
- 125000003342 alkenyl group Chemical group 0.000 abstract 2
- 125000000304 alkynyl group Chemical group 0.000 abstract 2
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- QXNVGIXVLWOKEQ-UHFFFAOYSA-N Disodium Chemical compound [Na][Na] QXNVGIXVLWOKEQ-UHFFFAOYSA-N 0.000 abstract 1
- 230000000172 allergic effect Effects 0.000 abstract 1
- 208000006673 asthma Diseases 0.000 abstract 1
- 208000010668 atopic eczema Diseases 0.000 abstract 1
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 1
- IMZMKUWMOSJXDT-UHFFFAOYSA-N cromoglycic acid Chemical compound O1C(C(O)=O)=CC(=O)C2=C1C=CC=C2OCC(O)COC1=CC=CC2=C1C(=O)C=C(C(O)=O)O2 IMZMKUWMOSJXDT-UHFFFAOYSA-N 0.000 abstract 1
- 125000001316 cycloalkyl alkyl group Chemical group 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 229960001340 histamine Drugs 0.000 abstract 1
- JCZMXVGQBBATMY-UHFFFAOYSA-N nitro acetate Chemical compound CC(=O)O[N+]([O-])=O JCZMXVGQBBATMY-UHFFFAOYSA-N 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
- C07D215/22—Oxygen atoms attached in position 2 or 4
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Pulmonology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Immunology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US59853975A | 1975-07-23 | 1975-07-23 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FR2318633A1 true FR2318633A1 (fr) | 1977-02-18 |
| FR2318633B1 FR2318633B1 (enrdf_load_stackoverflow) | 1978-12-22 |
Family
ID=24395967
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR7622494A Granted FR2318633A1 (fr) | 1975-07-23 | 1976-07-23 | Procede de preparation de derives de la quinoleine |
Country Status (17)
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS54130587A (en) * | 1978-03-30 | 1979-10-09 | Otsuka Pharmaceut Co Ltd | Carbostyryl derivative |
| IE52656B1 (en) * | 1981-04-07 | 1988-01-06 | Shell Int Research | Closure device |
| JPS60101445U (ja) * | 1983-12-17 | 1985-07-10 | 紀伊産業株式会社 | 密封容器 |
| JPH0621181B2 (ja) * | 1987-01-12 | 1994-03-23 | テルモ株式会社 | 親水性ポリフッ化ビニリデン多孔質膜の製造方法 |
| JPH0644827Y2 (ja) * | 1988-09-20 | 1994-11-16 | エヌオーケー株式会社 | キャップ |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2009119A1 (enrdf_load_stackoverflow) * | 1968-05-22 | 1970-01-30 | Basf Ag | |
| FR2205327A1 (en) * | 1972-11-02 | 1974-05-31 | Sandoz Sa | 1-Alkyl-4-alkoxy-2-quinolineones - as minor tranquillisers and their 3-carboxylic acid ester derivs. as inters |
| FR2229414A1 (enrdf_load_stackoverflow) * | 1973-05-19 | 1974-12-13 | Beecham Group Ltd |
-
1976
- 1976-07-12 DE DE19762631317 patent/DE2631317A1/de active Pending
- 1976-07-14 DK DK319276A patent/DK319276A/da unknown
- 1976-07-14 FI FI762046A patent/FI762046A7/fi not_active Application Discontinuation
- 1976-07-15 NO NO762489A patent/NO762489L/no unknown
- 1976-07-16 SE SE7608151A patent/SE7608151L/xx unknown
- 1976-07-19 NL NL7607968A patent/NL7607968A/xx unknown
- 1976-07-21 IL IL50090A patent/IL50090A0/xx unknown
- 1976-07-21 JP JP51086079A patent/JPS5225781A/ja active Pending
- 1976-07-21 DD DD193994A patent/DD126769A5/xx unknown
- 1976-07-21 PT PT65391A patent/PT65391B/pt unknown
- 1976-07-21 NZ NZ181532A patent/NZ181532A/xx unknown
- 1976-07-22 BE BE169152A patent/BE844414A/xx unknown
- 1976-07-22 ES ES450060A patent/ES450060A1/es not_active Expired
- 1976-07-22 YU YU01811/76A patent/YU181176A/xx unknown
- 1976-07-23 AU AU16209/76A patent/AU1620976A/en not_active Expired
- 1976-07-23 ZA ZA00764449A patent/ZA764449B/xx unknown
- 1976-07-23 FR FR7622494A patent/FR2318633A1/fr active Granted
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2009119A1 (enrdf_load_stackoverflow) * | 1968-05-22 | 1970-01-30 | Basf Ag | |
| FR2205327A1 (en) * | 1972-11-02 | 1974-05-31 | Sandoz Sa | 1-Alkyl-4-alkoxy-2-quinolineones - as minor tranquillisers and their 3-carboxylic acid ester derivs. as inters |
| FR2229414A1 (enrdf_load_stackoverflow) * | 1973-05-19 | 1974-12-13 | Beecham Group Ltd |
Also Published As
| Publication number | Publication date |
|---|---|
| PT65391A (fr) | 1976-08-01 |
| SE7608151L (sv) | 1977-01-24 |
| ES450060A1 (es) | 1977-12-01 |
| NL7607968A (nl) | 1977-01-25 |
| NO762489L (enrdf_load_stackoverflow) | 1977-01-25 |
| JPS5225781A (en) | 1977-02-25 |
| NZ181532A (en) | 1978-07-10 |
| IL50090A0 (en) | 1976-09-30 |
| FR2318633B1 (enrdf_load_stackoverflow) | 1978-12-22 |
| YU181176A (en) | 1982-05-31 |
| PT65391B (fr) | 1978-04-05 |
| DK319276A (da) | 1977-01-24 |
| ZA764449B (en) | 1978-03-29 |
| AU1620976A (en) | 1978-01-26 |
| FI762046A7 (enrdf_load_stackoverflow) | 1977-01-24 |
| DE2631317A1 (de) | 1977-02-17 |
| BE844414A (fr) | 1977-01-24 |
| DD126769A5 (enrdf_load_stackoverflow) | 1977-08-10 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ST | Notification of lapse |