FR2318157B1 - - Google Patents

Info

Publication number
FR2318157B1
FR2318157B1 FR7630727A FR7630727A FR2318157B1 FR 2318157 B1 FR2318157 B1 FR 2318157B1 FR 7630727 A FR7630727 A FR 7630727A FR 7630727 A FR7630727 A FR 7630727A FR 2318157 B1 FR2318157 B1 FR 2318157B1
Authority
FR
France
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
FR7630727A
Other versions
FR2318157A1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Queens University at Kingston
Original Assignee
Queens University at Kingston
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Queens University at Kingston filed Critical Queens University at Kingston
Publication of FR2318157A1 publication Critical patent/FR2318157A1/fr
Application granted granted Critical
Publication of FR2318157B1 publication Critical patent/FR2318157B1/fr
Granted legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
    • C07D205/085—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams with a nitrogen atom directly attached in position 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D499/88—Compounds with a double bond between positions 2 and 3 and a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D505/00—Heterocyclic compounds containing 5-oxa-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. oxacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
FR7630727A 1974-08-06 1976-10-13 Nouvelles azetidinones Granted FR2318157A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB34614/74A GB1510794A (en) 1974-08-06 1974-08-06 1-oxacephems and intermediates therefor

Publications (2)

Publication Number Publication Date
FR2318157A1 FR2318157A1 (fr) 1977-02-11
FR2318157B1 true FR2318157B1 (fr) 1979-03-09

Family

ID=10367850

Family Applications (3)

Application Number Title Priority Date Filing Date
FR7524276A Granted FR2281119A1 (fr) 1974-08-06 1975-08-04 1-oxacephemes
FR7630727A Granted FR2318157A1 (fr) 1974-08-06 1976-10-13 Nouvelles azetidinones
FR7630728A Granted FR2318158A1 (fr) 1974-08-06 1976-10-13 Azetidinones

Family Applications Before (1)

Application Number Title Priority Date Filing Date
FR7524276A Granted FR2281119A1 (fr) 1974-08-06 1975-08-04 1-oxacephemes

Family Applications After (1)

Application Number Title Priority Date Filing Date
FR7630728A Granted FR2318158A1 (fr) 1974-08-06 1976-10-13 Azetidinones

Country Status (12)

Country Link
US (1) US4013653A (fr)
JP (1) JPS5141385A (fr)
AT (1) AT342769B (fr)
BE (1) BE832174A (fr)
CA (1) CA1052787A (fr)
CH (1) CH616681A5 (fr)
DE (1) DE2531843A1 (fr)
DK (1) DK356075A (fr)
FI (1) FI63237C (fr)
FR (3) FR2281119A1 (fr)
GB (1) GB1510794A (fr)
NL (1) NL7509353A (fr)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4226866A (en) * 1972-11-06 1980-10-07 Merck & Co., Inc. Novel antibiotic analogues of cephalosporins
US4108992A (en) * 1975-05-10 1978-08-22 Beecham Group Limited Cephalosporin analogues and compositions
US4143038A (en) * 1975-11-12 1979-03-06 Shionogi & Co., Ltd. Cephalosporin analogues
CA1085392A (fr) * 1976-03-25 1980-09-09 Masayuki Narisada Arylmalonamido-1-oxadethiacephalosporines
JPS607635B2 (ja) * 1976-04-27 1985-02-26 塩野義製薬株式会社 オキサゾリジン化合物
JPS609515B2 (ja) * 1976-08-09 1985-03-11 塩野義製薬株式会社 ３′−ノルオキサセファロスポリン類
US4197402A (en) * 1976-08-09 1980-04-08 Shionogi & Co., Ltd. Cephalosporin analogues
JPS5331690A (en) * 1976-09-01 1978-03-25 Shionogi & Co Ltd Oxadithiacephalosporins
US4089956A (en) * 1976-09-08 1978-05-16 Smithkline Corporation 7-Acylamino-8-oxo-3-oxa-1-azabicyclo[4.2.0]octane-2-carboxylic acid derivatives and bactericidal compositions and use thereof
US4187375A (en) * 1976-09-08 1980-02-05 Smithkline Corporation Process for preparing oxazine ring compounds
AU514377B2 (en) * 1977-02-15 1981-02-05 Shionogi & Co., Ltd. l-OXADETHIACEPHAM COMPOUNDS
US4533730A (en) * 1977-02-15 1985-08-06 Shionogi & Co., Ltd. 1-Oxadethiacepham compounds
US4443598A (en) * 1977-02-15 1984-04-17 Shionogi & Co., Ltd. 1-Oxadethiacepham compounds
JPS53105491A (en) 1977-02-25 1978-09-13 Shionogi & Co Ltd Oxazolinoazethidinylbutyrylic acid derivatives
CA1100962A (fr) * 1977-04-28 1981-05-12 Yoshio Hamashima Haloarylmalonamidooxacephalosporines
IT1102408B (it) * 1977-12-23 1985-10-07 Fujisawa Pharmaceutical Co Composti analoghi della cefalosforina e procedimenti per la loro preparazione
US4243588A (en) * 1979-06-19 1981-01-06 Eli Lilly And Company Process for novel oxazolinoazetidinones
JPS5690088A (en) * 1979-11-02 1981-07-21 Meiji Seika Kaisha Ltd Novel cephalosporin analog compound
US4301282A (en) * 1980-09-17 1981-11-17 Eli Lilly And Company 1-Oxa-β-lactam antibiotics
US4368156A (en) * 1981-03-09 1983-01-11 Eli Lilly And Company Preparation of 4-haloazetidin-2-ones from 4-sulfinoazetidin-2-ones
US4500456A (en) * 1981-03-09 1985-02-19 Eli Lilly And Company Preparation of 4-fluoroazetidinones using FClO3
US4391975A (en) * 1981-12-15 1983-07-05 Queen's University At Kingston Process for 1-oxacephem derivatives
DE3225269A1 (de) * 1982-07-06 1984-01-12 Bayer Ag, 5090 Leverkusen Verfahren zur herstellung von 7-amino-1-dethia-1-oxa-3-hydroxymethyl-cephem-4-carbonsaeuren
JPS59104389A (ja) * 1982-12-06 1984-06-16 Shionogi & Co Ltd オキサセファム誘導体
US4558123A (en) * 1983-07-22 1985-12-10 Eli Lilly And Company 3-Exomethylene cephalosporins
JP2525170B2 (ja) * 1987-03-09 1996-08-14 大塚製薬株式会社 ２―オキサイソセフェム誘導体の製造方法
US5412094A (en) * 1993-06-28 1995-05-02 Eli Lilly And Company Bicyclic beta-lactam/paraben complexes
SK13897A3 (en) 1996-02-06 1998-05-06 Pliva Pharm & Chem Works 3-bromo- and 3,3-dibromo-4-oxo-1-azetidines, method for preparation thereof and their use
HRP970146A2 (en) * 1997-03-13 1998-10-31 Mice Kovacevic Epoxi-azetidines, preparation and use
AU2002322247A1 (en) * 2001-08-03 2003-02-17 Chirologix Pharmaceutical Inc. Antibacterial oxazinones and methods for their use and synthesis
WO2003018565A1 (fr) * 2001-08-29 2003-03-06 Chirologix Pharmaceuticals Inc. Procede de synthese d'oxazinones

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1914366A1 (de) * 1969-03-21 1970-10-01 Bayer Ag Arzneimittel auf Basis neuer,heterocyclischer Verbindungen
CH581140A5 (fr) * 1971-05-28 1976-10-29 Lilly Co Eli

Also Published As

Publication number Publication date
US4013653A (en) 1977-03-22
FR2318158B1 (fr) 1979-03-23
AT342769B (de) 1978-04-25
FR2318157A1 (fr) 1977-02-11
DE2531843A1 (de) 1976-02-19
JPS5141385A (en) 1976-04-07
FI752225A (fr) 1976-02-07
DK356075A (da) 1976-02-07
CA1052787A (fr) 1979-04-17
GB1510794A (en) 1978-05-17
NL7509353A (nl) 1976-02-10
FI63237B (fi) 1983-01-31
FR2318158A1 (fr) 1977-02-11
BE832174A (fr) 1975-12-01
FI63237C (fi) 1983-05-10
CH616681A5 (fr) 1980-04-15
FR2281119A1 (fr) 1976-03-05
ATA599175A (de) 1977-08-15
FR2281119B1 (fr) 1982-04-23

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Legal Events

Date Code Title Description
ST Notification of lapse