DK356075A - Fremgangsmade til fremstilling af 1-oxacephemer samt mellemprodukter dertil - Google Patents
Fremgangsmade til fremstilling af 1-oxacephemer samt mellemprodukter dertilInfo
- Publication number
- DK356075A DK356075A DK356075A DK356075A DK356075A DK 356075 A DK356075 A DK 356075A DK 356075 A DK356075 A DK 356075A DK 356075 A DK356075 A DK 356075A DK 356075 A DK356075 A DK 356075A
- Authority
- DK
- Denmark
- Prior art keywords
- oxacephemes
- procedure
- preparation
- intermediate products
- products
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
- C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
- C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
- C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
- C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
- C07D205/085—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams with a nitrogen atom directly attached in position 3
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D499/88—Compounds with a double bond between positions 2 and 3 and a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D505/00—Heterocyclic compounds containing 5-oxa-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. oxacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB34614/74A GB1510794A (en) | 1974-08-06 | 1974-08-06 | 1-oxacephems and intermediates therefor |
Publications (1)
Publication Number | Publication Date |
---|---|
DK356075A true DK356075A (da) | 1976-02-07 |
Family
ID=10367850
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK356075A DK356075A (da) | 1974-08-06 | 1975-08-05 | Fremgangsmade til fremstilling af 1-oxacephemer samt mellemprodukter dertil |
Country Status (12)
Country | Link |
---|---|
US (1) | US4013653A (fr) |
JP (1) | JPS5141385A (fr) |
AT (1) | AT342769B (fr) |
BE (1) | BE832174A (fr) |
CA (1) | CA1052787A (fr) |
CH (1) | CH616681A5 (fr) |
DE (1) | DE2531843A1 (fr) |
DK (1) | DK356075A (fr) |
FI (1) | FI63237C (fr) |
FR (3) | FR2281119A1 (fr) |
GB (1) | GB1510794A (fr) |
NL (1) | NL7509353A (fr) |
Families Citing this family (31)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4226866A (en) * | 1972-11-06 | 1980-10-07 | Merck & Co., Inc. | Novel antibiotic analogues of cephalosporins |
US4108992A (en) * | 1975-05-10 | 1978-08-22 | Beecham Group Limited | Cephalosporin analogues and compositions |
US4143038A (en) * | 1975-11-12 | 1979-03-06 | Shionogi & Co., Ltd. | Cephalosporin analogues |
CA1085392A (fr) * | 1976-03-25 | 1980-09-09 | Masayuki Narisada | Arylmalonamido-1-oxadethiacephalosporines |
JPS607635B2 (ja) * | 1976-04-27 | 1985-02-26 | 塩野義製薬株式会社 | オキサゾリジン化合物 |
JPS609515B2 (ja) * | 1976-08-09 | 1985-03-11 | 塩野義製薬株式会社 | 3′−ノルオキサセファロスポリン類 |
US4197402A (en) * | 1976-08-09 | 1980-04-08 | Shionogi & Co., Ltd. | Cephalosporin analogues |
JPS5331690A (en) * | 1976-09-01 | 1978-03-25 | Shionogi & Co Ltd | Oxadithiacephalosporins |
US4089956A (en) * | 1976-09-08 | 1978-05-16 | Smithkline Corporation | 7-Acylamino-8-oxo-3-oxa-1-azabicyclo[4.2.0]octane-2-carboxylic acid derivatives and bactericidal compositions and use thereof |
US4187375A (en) * | 1976-09-08 | 1980-02-05 | Smithkline Corporation | Process for preparing oxazine ring compounds |
AU514377B2 (en) * | 1977-02-15 | 1981-02-05 | Shionogi & Co., Ltd. | l-OXADETHIACEPHAM COMPOUNDS |
US4533730A (en) * | 1977-02-15 | 1985-08-06 | Shionogi & Co., Ltd. | 1-Oxadethiacepham compounds |
US4443598A (en) * | 1977-02-15 | 1984-04-17 | Shionogi & Co., Ltd. | 1-Oxadethiacepham compounds |
JPS53105491A (en) | 1977-02-25 | 1978-09-13 | Shionogi & Co Ltd | Oxazolinoazethidinylbutyrylic acid derivatives |
CA1100962A (fr) * | 1977-04-28 | 1981-05-12 | Yoshio Hamashima | Haloarylmalonamidooxacephalosporines |
IT1102408B (it) * | 1977-12-23 | 1985-10-07 | Fujisawa Pharmaceutical Co | Composti analoghi della cefalosforina e procedimenti per la loro preparazione |
US4243588A (en) * | 1979-06-19 | 1981-01-06 | Eli Lilly And Company | Process for novel oxazolinoazetidinones |
JPS5690088A (en) * | 1979-11-02 | 1981-07-21 | Meiji Seika Kaisha Ltd | Novel cephalosporin analog compound |
US4301282A (en) * | 1980-09-17 | 1981-11-17 | Eli Lilly And Company | 1-Oxa-β-lactam antibiotics |
US4368156A (en) * | 1981-03-09 | 1983-01-11 | Eli Lilly And Company | Preparation of 4-haloazetidin-2-ones from 4-sulfinoazetidin-2-ones |
US4500456A (en) * | 1981-03-09 | 1985-02-19 | Eli Lilly And Company | Preparation of 4-fluoroazetidinones using FClO3 |
US4391975A (en) * | 1981-12-15 | 1983-07-05 | Queen's University At Kingston | Process for 1-oxacephem derivatives |
DE3225269A1 (de) * | 1982-07-06 | 1984-01-12 | Bayer Ag, 5090 Leverkusen | Verfahren zur herstellung von 7-amino-1-dethia-1-oxa-3-hydroxymethyl-cephem-4-carbonsaeuren |
JPS59104389A (ja) * | 1982-12-06 | 1984-06-16 | Shionogi & Co Ltd | オキサセファム誘導体 |
US4558123A (en) * | 1983-07-22 | 1985-12-10 | Eli Lilly And Company | 3-Exomethylene cephalosporins |
JP2525170B2 (ja) * | 1987-03-09 | 1996-08-14 | 大塚製薬株式会社 | 2―オキサイソセフェム誘導体の製造方法 |
US5412094A (en) * | 1993-06-28 | 1995-05-02 | Eli Lilly And Company | Bicyclic beta-lactam/paraben complexes |
SK13897A3 (en) | 1996-02-06 | 1998-05-06 | Pliva Pharm & Chem Works | 3-bromo- and 3,3-dibromo-4-oxo-1-azetidines, method for preparation thereof and their use |
HRP970146A2 (en) * | 1997-03-13 | 1998-10-31 | Mice Kovacevic | Epoxi-azetidines, preparation and use |
AU2002322247A1 (en) * | 2001-08-03 | 2003-02-17 | Chirologix Pharmaceutical Inc. | Antibacterial oxazinones and methods for their use and synthesis |
WO2003018565A1 (fr) * | 2001-08-29 | 2003-03-06 | Chirologix Pharmaceuticals Inc. | Procede de synthese d'oxazinones |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE1914366A1 (de) * | 1969-03-21 | 1970-10-01 | Bayer Ag | Arzneimittel auf Basis neuer,heterocyclischer Verbindungen |
CH581140A5 (fr) * | 1971-05-28 | 1976-10-29 | Lilly Co Eli |
-
1974
- 1974-08-06 GB GB34614/74A patent/GB1510794A/en not_active Expired
-
1975
- 1975-07-16 DE DE19752531843 patent/DE2531843A1/de not_active Withdrawn
- 1975-07-21 US US05/597,128 patent/US4013653A/en not_active Expired - Lifetime
- 1975-07-21 CA CA231,940A patent/CA1052787A/fr not_active Expired
- 1975-08-01 AT AT599175A patent/AT342769B/de not_active IP Right Cessation
- 1975-08-04 FR FR7524276A patent/FR2281119A1/fr active Granted
- 1975-08-05 FI FI752225A patent/FI63237C/fi not_active IP Right Cessation
- 1975-08-05 CH CH1019675A patent/CH616681A5/fr not_active IP Right Cessation
- 1975-08-05 DK DK356075A patent/DK356075A/da unknown
- 1975-08-06 JP JP50095724A patent/JPS5141385A/ja active Pending
- 1975-08-06 BE BE158981A patent/BE832174A/fr unknown
- 1975-08-06 NL NL7509353A patent/NL7509353A/xx not_active Application Discontinuation
-
1976
- 1976-10-13 FR FR7630727A patent/FR2318157A1/fr active Granted
- 1976-10-13 FR FR7630728A patent/FR2318158A1/fr active Granted
Also Published As
Publication number | Publication date |
---|---|
US4013653A (en) | 1977-03-22 |
FR2318158B1 (fr) | 1979-03-23 |
AT342769B (de) | 1978-04-25 |
FR2318157B1 (fr) | 1979-03-09 |
FR2318157A1 (fr) | 1977-02-11 |
DE2531843A1 (de) | 1976-02-19 |
JPS5141385A (en) | 1976-04-07 |
FI752225A (fr) | 1976-02-07 |
CA1052787A (fr) | 1979-04-17 |
GB1510794A (en) | 1978-05-17 |
NL7509353A (nl) | 1976-02-10 |
FI63237B (fi) | 1983-01-31 |
FR2318158A1 (fr) | 1977-02-11 |
BE832174A (fr) | 1975-12-01 |
FI63237C (fi) | 1983-05-10 |
CH616681A5 (fr) | 1980-04-15 |
FR2281119A1 (fr) | 1976-03-05 |
ATA599175A (de) | 1977-08-15 |
FR2281119B1 (fr) | 1982-04-23 |
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