FR2310771A1 - Nouveaux sels d'((oxepannylidene-2)methyl)triphenylphosphonium, utiles notamment comme analgesiques et leur procede de preparation - Google Patents

Nouveaux sels d'((oxepannylidene-2)methyl)triphenylphosphonium, utiles notamment comme analgesiques et leur procede de preparation

Info

Publication number
FR2310771A1
FR2310771A1 FR7614693A FR7614693A FR2310771A1 FR 2310771 A1 FR2310771 A1 FR 2310771A1 FR 7614693 A FR7614693 A FR 7614693A FR 7614693 A FR7614693 A FR 7614693A FR 2310771 A1 FR2310771 A1 FR 2310771A1
Authority
FR
France
Prior art keywords
oxepannylidene
triphenylphosphonium
analgesics
methyl
useful
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7614693A
Other languages
English (en)
Other versions
FR2310771B1 (fr
Inventor
R A Mueller
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GD Searle LLC
Original Assignee
GD Searle LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by GD Searle LLC filed Critical GD Searle LLC
Publication of FR2310771A1 publication Critical patent/FR2310771A1/fr
Application granted granted Critical
Publication of FR2310771B1 publication Critical patent/FR2310771B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/655—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms
    • C07F9/65525—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms the oxygen atom being part of a seven-(or more) membered ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/58—Preparation of carboxylic acid halides
    • C07C51/60—Preparation of carboxylic acid halides by conversion of carboxylic acids or their anhydrides or esters, lactones, salts into halides with the same carboxylic acid part
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C53/00—Saturated compounds having only one carboxyl group bound to an acyclic carbon atom or hydrogen
    • C07C53/38—Acyl halides
    • C07C53/46—Acyl halides containing halogen outside the carbonyl halide group
    • C07C53/50—Acyl halides containing halogen outside the carbonyl halide group of acids containing three or more carbon atoms
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Pyrane Compounds (AREA)
FR7614693A 1975-05-15 1976-05-14 Nouveaux sels d'((oxepannylidene-2)methyl)triphenylphosphonium, utiles notamment comme analgesiques et leur procede de preparation Granted FR2310771A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/577,675 US3997588A (en) 1975-05-15 1975-05-15 3,5-Bisoxygenated 2-(ω-halo-3-oxygenated-1-alkenyl)-cyclopentane-1-heptanoic acids and derivatives thereof

Publications (2)

Publication Number Publication Date
FR2310771A1 true FR2310771A1 (fr) 1976-12-10
FR2310771B1 FR2310771B1 (fr) 1978-11-17

Family

ID=24309688

Family Applications (2)

Application Number Title Priority Date Filing Date
FR7614692A Granted FR2310754A1 (fr) 1975-05-15 1976-05-14 Acides (o-halo-oxygene en 3 alcene-1 yl)-2 cyclopentaneheptanoiques-1 bis-oxygenes en 3,5, derives correspondants et procede de leur preparation
FR7614693A Granted FR2310771A1 (fr) 1975-05-15 1976-05-14 Nouveaux sels d'((oxepannylidene-2)methyl)triphenylphosphonium, utiles notamment comme analgesiques et leur procede de preparation

Family Applications Before (1)

Application Number Title Priority Date Filing Date
FR7614692A Granted FR2310754A1 (fr) 1975-05-15 1976-05-14 Acides (o-halo-oxygene en 3 alcene-1 yl)-2 cyclopentaneheptanoiques-1 bis-oxygenes en 3,5, derives correspondants et procede de leur preparation

Country Status (16)

Country Link
US (1) US3997588A (fr)
JP (2) JPS51141888A (fr)
AU (2) AU499157B2 (fr)
BE (1) BE841848A (fr)
CA (1) CA1095514A (fr)
CH (1) CH624930A5 (fr)
DE (2) DE2621539A1 (fr)
DK (1) DK214076A (fr)
ES (1) ES447942A1 (fr)
FR (2) FR2310754A1 (fr)
GB (1) GB1497011A (fr)
IE (1) IE43689B1 (fr)
NL (1) NL7605189A (fr)
NZ (1) NZ180863A (fr)
SE (1) SE7605518L (fr)
ZA (1) ZA762888B (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2493323A1 (fr) * 1980-08-06 1982-05-07 Searle & Co Nouveaux sels d'oxacycloalkylidenemethyltripheny (alkyl) phosphonium utiles notamment comme agents analgesiques moderes et leur procede de preparation

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4056562A (en) * 1975-05-15 1977-11-01 G. D. Searle & Co. 3,5-Bisoxygenated 2-(ω-halo-3-oxygenated-1-alkenyl)-cyclopentane-1-heptanoic acids and derivatives thereof
JPS6022708B2 (ja) * 1977-07-14 1985-06-03 小野薬品工業株式会社 プロスタグランジン類似化合物
SE531315C2 (sv) * 2005-04-15 2009-02-17 Jerzy Hawranek Axiell rörvärmeväxlare
JP4648340B2 (ja) * 2006-02-07 2011-03-09 株式会社アールテック・ウエノ １５−ケトプロスタグランジンｅ誘導体の製造法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3833640A (en) * 1968-07-29 1974-09-03 Upjohn Co Prostaglandin e1,f1,and a1 analogs
US3843712A (en) * 1971-07-13 1974-10-22 Upjohn Co Endo-bicyclo(3.1.0)-hexane glycol intermediates for preparing prostaglandins e1,a1,and analogs thereof
US3853951A (en) * 1971-07-14 1974-12-10 American Cyanamid Co Preparation of 9-oxo-13-trans-prostenoic acid esters by alanate addition to cyclopentenone

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
NEANT *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2493323A1 (fr) * 1980-08-06 1982-05-07 Searle & Co Nouveaux sels d'oxacycloalkylidenemethyltripheny (alkyl) phosphonium utiles notamment comme agents analgesiques moderes et leur procede de preparation

Also Published As

Publication number Publication date
SE7605518L (sv) 1976-11-16
AU499841B2 (en) 1979-05-03
ZA762888B (en) 1977-06-29
JPS51141888A (en) 1976-12-07
BE841848A (fr) 1976-11-16
DK214076A (da) 1976-11-16
FR2310754A1 (fr) 1976-12-10
NL7605189A (nl) 1976-11-17
DE2621576A1 (de) 1976-12-02
AU1395776A (en) 1977-11-17
CH624930A5 (fr) 1981-08-31
GB1497011A (en) 1978-01-05
FR2310754B1 (fr) 1979-09-28
ES447942A1 (es) 1977-06-16
AU1395876A (en) 1977-11-17
JPS51141845A (en) 1976-12-07
NZ180863A (en) 1978-06-20
AU499157B2 (en) 1979-04-05
IE43689B1 (en) 1981-05-06
IE43689L (en) 1976-11-15
DE2621539A1 (de) 1976-11-25
FR2310771B1 (fr) 1978-11-17
CA1095514A (fr) 1981-02-10
US3997588A (en) 1976-12-14

Similar Documents

Publication Publication Date Title
BE827127A (fr) Nouveaux derives d'acide oxy-16 prostanoique, leur procede de preparation et leur utilisation therapeutique
LU79335A1 (fr) Procede de preparation de derives d'acetamides utiles notamment en therapeutique
FR2303080A1 (fr) Procede de preparation d'une composition microbienne hydrosoluble et composition obtenue
BE866031A (fr) Nouveaux 2-(2,2-diarylalkyl)-1-azabicyclo (2,2,2)octanes, utiles notamment comme antidiarrheiques, et leur procede de preparation
FR2326922A1 (fr) Nouveaux sels de pilocarpine et leur procede de preparation
FR2317934A1 (fr) Nouveaux 16-dehydro-androstanes, utiles notamment en dermatologie, et leur procede de preparation
FR2325368A1 (fr) Nouveaux derives phenylacetiques utiles notamment comme hypolipemiants et leur procede de preparation
FR2310771A1 (fr) Nouveaux sels d'((oxepannylidene-2)methyl)triphenylphosphonium, utiles notamment comme analgesiques et leur procede de preparation
BE856464A (fr) Nouveaux derives 16-acythio de l'acide fusidique, utiles notamment comme antimicrobiens et leur procede de preparation
BE884782A (fr) Nouveaux acides alcoxybenzofuranne-2-carboxyliques, leurs sels et esters, utiles notamment comme agents hypolipemiants, et leur procede de preparation
FR2316937A1 (fr) Nouveaux 9-hydroxy-7,8,9,10-tetrahydro-6h-dibenzo (b)-(d)pyrannes et pyrannones, utiles notamment comme analgesiques, et leur procede de preparation
FR2304605A1 (fr) Nouveaux acides amidosulfocarboxyliques et leurs sels, leur procede de preparation et leur utilisation notamment comme agents protecteurs anticorrosion
FR2320746A1 (fr) Nouveau thiopyranno(4,3-c)pyrasoles, utiles notamment comme anti-inflammatoires et leur procede de preparation
BE866548A (fr) Nouveaux derives d'acide naphtalenetris (sulfonamidobenzenemono-,di- ou tricarboxyliques), utiles notamment comme inhibiteurs du complement, et leur procede de preparation
BE875013A (fr) Nouveaux derives de 2-hydroxymethyl-pyrazine, utiles notamment comme hypolipemiants, et leur procede de preparation
FR2299859A1 (fr) Derives d'acide glycyrrhetinique, leur procede de preparation et leur application
FR2348217A1 (fr) Nouveaux bis-penicillanoyloxyalcanes utiles notamment comme antibiotiques et leur procede de preparation
BE839521A (fr) Nouveaux carbamates de 2-halogenoergolines et 2-halogenoergolenes, utiles notamment comme vasodilatateurs, et leur procede de preparation
BE856326A (fr) Nouveaux derives d'acide prostanoique et leur procede de preparation
BE833079A (fr) Derives n-acyles de l'orgoteine, utiles notamment comme anti-inflammatoires, et leur procede de preparation
BE873412A (fr) Nouveaux derives d'acides 1,5-cyclohexadienecarboxyliques substitues, utiles notamment comme antiepileptiques, et leur procede de preparation
BE840944A (fr) Procede de preparation d'acides carboxy-alcane-phosphoniques et d'acides carboxy-alkyl-phosphiniques
MC1058A1 (fr) Procede de preparation d'hydroxocobalamine et de ses sels
BE873411A (fr) Nouveaux derives d'acides 1,4-cyclohexadienecarboxyliques substitues, utiles notamment comme antiepileptiques, et leur procede de preparation
BE838890R (fr) Nouvelles isoxy-11-protaglandines et des series e et f, utiles notamment comme inhibiteurs de la secretion gastrique d'acide et leur procede de preparation

Legal Events

Date Code Title Description
ST Notification of lapse