FR2295741A1 - Derives de la pyridoxine, leur procede de preparation et leur application - Google Patents
Derives de la pyridoxine, leur procede de preparation et leur applicationInfo
- Publication number
- FR2295741A1 FR2295741A1 FR7531075A FR7531075A FR2295741A1 FR 2295741 A1 FR2295741 A1 FR 2295741A1 FR 7531075 A FR7531075 A FR 7531075A FR 7531075 A FR7531075 A FR 7531075A FR 2295741 A1 FR2295741 A1 FR 2295741A1
- Authority
- FR
- France
- Prior art keywords
- hypolipaemic
- pyridoxine
- amino acids
- phosphate salts
- hypocholesterolaemic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 230000000055 hyoplipidemic effect Effects 0.000 title abstract 2
- 150000001413 amino acids Chemical class 0.000 title 1
- 230000000871 hypocholesterolemic effect Effects 0.000 title 1
- WHOMFKWHIQZTHY-UHFFFAOYSA-L pyridoxine 5'-phosphate(2-) Chemical class CC1=NC=C(COP([O-])([O-])=O)C(CO)=C1O WHOMFKWHIQZTHY-UHFFFAOYSA-L 0.000 title 1
- XXJGBENTLXFVFI-UHFFFAOYSA-N 1-amino-methylene Chemical group N[CH2] XXJGBENTLXFVFI-UHFFFAOYSA-N 0.000 abstract 1
- 239000003529 anticholesteremic agent Substances 0.000 abstract 1
- 125000000816 ethylene group Chemical group [H]C([H])([*:1])C([H])([H])[*:2] 0.000 abstract 1
- 125000002485 formyl group Chemical group [H]C(*)=O 0.000 abstract 1
- CBOIHMRHGLHBPB-UHFFFAOYSA-N hydroxymethyl Chemical group O[CH2] CBOIHMRHGLHBPB-UHFFFAOYSA-N 0.000 abstract 1
- WHOMFKWHIQZTHY-UHFFFAOYSA-N pyridoxine 5'-phosphate Chemical class CC1=NC=C(COP(O)(O)=O)C(CO)=C1O WHOMFKWHIQZTHY-UHFFFAOYSA-N 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
- C07F9/576—Six-membered rings
- C07F9/58—Pyridine rings
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE2461742A DE2461742C2 (de) | 1974-12-28 | 1974-12-28 | Pyridoxin-5'-phosphorsäureester-Derivate sowie deren Herstellung und diese Verbindungen enthaltende Arzneimittel |
Publications (2)
Publication Number | Publication Date |
---|---|
FR2295741A1 true FR2295741A1 (fr) | 1976-07-23 |
FR2295741B1 FR2295741B1 (fr) | 1979-09-14 |
Family
ID=5934705
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR7531075A Granted FR2295741A1 (fr) | 1974-12-28 | 1975-10-10 | Derives de la pyridoxine, leur procede de preparation et leur application |
Country Status (2)
Country | Link |
---|---|
DE (1) | DE2461742C2 (fr) |
FR (1) | FR2295741A1 (fr) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0282696A2 (fr) * | 1987-02-18 | 1988-09-21 | Steigerwald Arzneimittelwerk Gmbh | Emploi de dérivés de pyridoxine pour la prophylaxie et le traitement de l'hyperlipémie et de l'athérosclérose |
EP0458287A2 (fr) * | 1990-05-25 | 1991-11-27 | Steigerwald Arzneimittelwerk Gmbh | Utilisation de magnésium-pyridoxal-5'-phosphate-glutaminate pour la prévention des maladies résultant des lésions vasculaires |
Families Citing this family (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6716858B1 (en) | 1995-08-28 | 2004-04-06 | Kansas University Medical Center | Methods for inhibiting diabetic complications |
US6228858B1 (en) | 1995-09-12 | 2001-05-08 | University Of Kansas Medical Center | Advanced glycation end-product intermediaries and post-amadori inhibition |
US6740668B1 (en) | 1995-08-28 | 2004-05-25 | Kansas University Medical Center | Methods for inhibiting diabetic complications |
DE19532625C2 (de) * | 1995-09-04 | 2000-04-20 | Steigerwald Arzneimittelwerk | Verfahren zur Herstellung von Magnesium-pyridoxal-5'-phosphat-glutamat und dabei erhaltene Zwischenprodukte |
US6730686B1 (en) | 1995-09-12 | 2004-05-04 | Kansas University Medical Center | Methods for inhibiting oxidative modification of proteins |
US6750209B1 (en) | 1995-09-12 | 2004-06-15 | Kansas University Medical Center | Advanced glycation end-product intermediaries and post-amadori inhibition |
US5744451A (en) | 1995-09-12 | 1998-04-28 | Warner-Lambert Company | N-substituted glutamic acid derivatives with interleukin-1 β converting enzyme inhibitory activity |
US7030146B2 (en) | 1996-09-10 | 2006-04-18 | University Of South Carolina | Methods for treating diabetic neuropathy |
US6043259A (en) * | 1998-07-09 | 2000-03-28 | Medicure Inc. | Treatment of cardiovascular and related pathologies |
WO2000022094A2 (fr) * | 1998-10-09 | 2000-04-20 | Kansas University Medical Center | Procede permettant d'inhiber la modification oxydative des proteines |
ES2250112T3 (es) | 1999-03-08 | 2006-04-16 | Medicure Inc. | Analogos de piridoxal para el tratamiento de trastornos causados por carencia de vitamina b6. |
CA2376029A1 (fr) | 1999-07-13 | 2001-01-18 | Medicure Inc. | Traitement du diabete et des pathologies associees |
WO2001013900A2 (fr) | 1999-08-24 | 2001-03-01 | Medicure International Inc. | Traitement des pathologies cardio-vasculaires et connexes |
ATE293119T1 (de) | 2000-02-29 | 2005-04-15 | Medicure Int Inc | Cardioprotektive phosphonate |
AU784840B2 (en) | 2000-03-28 | 2006-07-06 | Medicure International Inc. | Treatment of cerebrovascular disease |
EP1299358B1 (fr) | 2000-07-07 | 2007-06-13 | Medicure International Inc. | Analogues de pyridoxine et de pyridoxal comme agents de therapie cardio-vasculaire |
US6897228B2 (en) | 2000-07-07 | 2005-05-24 | Medicure International Inc. | Pyridoxine and pyridoxal analogues: new uses |
US6548519B1 (en) | 2001-07-06 | 2003-04-15 | Medicure International Inc. | Pyridoxine and pyridoxal analogues: novel uses |
AU2005304220A1 (en) | 2004-10-28 | 2006-05-18 | Medicure International Inc. | Dual antiplatelet/anticoagulant pyridoxine analogs |
US7375112B2 (en) * | 2005-01-05 | 2008-05-20 | Medicure International Inc. | Compounds and methods for regulating triglyceride levels |
WO2006087232A1 (fr) * | 2005-02-17 | 2006-08-24 | Instituto Del Metabolismo Celular, S.L. | Acide l-aspartique destine au traitement de problemes lies au metabolisme des graisses ou du glucose |
-
1974
- 1974-12-28 DE DE2461742A patent/DE2461742C2/de not_active Expired
-
1975
- 1975-10-10 FR FR7531075A patent/FR2295741A1/fr active Granted
Non-Patent Citations (1)
Title |
---|
NEANT * |
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0282696A2 (fr) * | 1987-02-18 | 1988-09-21 | Steigerwald Arzneimittelwerk Gmbh | Emploi de dérivés de pyridoxine pour la prophylaxie et le traitement de l'hyperlipémie et de l'athérosclérose |
EP0282696A3 (en) * | 1987-02-18 | 1989-06-14 | Ulrich Dr. Speck | Use of pyridoxine derivatives in the prophylaxis and treatment of hyperlipemia and atherosclerosis |
EP0458287A2 (fr) * | 1990-05-25 | 1991-11-27 | Steigerwald Arzneimittelwerk Gmbh | Utilisation de magnésium-pyridoxal-5'-phosphate-glutaminate pour la prévention des maladies résultant des lésions vasculaires |
EP0458287A3 (en) * | 1990-05-25 | 1992-04-08 | Steigerwald Arzneimittelwerk Gmbh | Use of magnesium-pyridoxal-5'-phosphate-glutaminate for the prevention of diseases which result from vascular lesions |
Also Published As
Publication number | Publication date |
---|---|
FR2295741B1 (fr) | 1979-09-14 |
DE2461742C2 (de) | 1983-01-27 |
DE2461742A1 (de) | 1976-07-08 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
FR2295741A1 (fr) | Derives de la pyridoxine, leur procede de preparation et leur application | |
GB1527191A (en) | Process for the production of n-phosphonomethyl glycine | |
GB1377687A (en) | Aminoalkyl esters of perfluoroalkyl-terminated alkylene thioalkanoic acids and derivatives thereof | |
DE3867445D1 (de) | Injizierbare loesung des thioctsaeuresalzes mit trometamol und/oder basischen aminosaeuren. | |
SE7710114L (sv) | 7-acylamino-8-oxo-3-oxa-1-azabicyklo(4.2.0)oktan-2-karbonsyraderivat | |
GB1456627A (en) | Pyridobenzodiazepinones | |
BG34036A3 (en) | A method of obtaining propargyl- 2- phenylamino- imidazolines- (2) and their acid salts | |
IL51272A (en) | Production of 3,3-dimethyl-2-oxo-butyric acid salts | |
ATE35994T1 (de) | Dihydroxyalkandiphosphonsaeuren. | |
ATE9328T1 (de) | 2-nitro-5-(substituiertes phenoxy) phenylalkanon- oxim- und -imin-derivate mit herbizider wirkung. | |
ES435003A1 (es) | Un proceso para la produccion de un compuesto cefem. | |
CH609669A5 (en) | Process for the preparation of metformin clofibrate | |
ES444508A1 (es) | Procedimiento para la preparacion de florogucina. | |
NL7410333A (en) | 2'-Aminoethyl 3,5'-dimethyl (thio)benzoates - as anti-ulcerogenic agents | |
FR2276035A1 (fr) | Nouveaux derives de l'indane | |
ZA83851B (en) | Carbacyclins, process for the preparation thereof, and use thereof as medicinal agents | |
ES8604556A1 (es) | Procedimiento para preparar derivados de flaveno y tioflave-no | |
GB1364615A (en) | Preparation of n -diethylaminoethyl - 2 - methoxy- 5 - methyl sulphonylbenzamide | |
EP0147152A3 (en) | Improvements in or relating to novel salts of dimeric indole-dihydroindole alkaloids | |
FR2278326A1 (fr) | Derives de l'acide 3,5 dimethyl-benzoique | |
FR2298321A1 (fr) | Medicament a base de cinnarizine et d'acides phenoxyalcane-carboxyliques ou de leurs derives, | |
GB1355005A (en) | Process for making betaines | |
FR2258186A1 (en) | 10-((4-hydroxyethylpiperidino)alkyl)-phenothiazines - with antiemetic activity | |
FR2290907A2 (fr) | Nouveaux derives de la phenothiazine, leur preparation et les compositions qui les contiennent | |
ES8601695A1 (es) | Procedimiento para la preparacion de compuestos de pteridina |