FR2265368A1 - Substd. tetrahydro-gamma-carbolines and pyrrolo-(3,4-b)-indoles - as tranquillizers for the treatment of schizophrenia - Google Patents

Substd. tetrahydro-gamma-carbolines and pyrrolo-(3,4-b)-indoles - as tranquillizers for the treatment of schizophrenia

Info

Publication number
FR2265368A1
FR2265368A1 FR7510139A FR7510139A FR2265368A1 FR 2265368 A1 FR2265368 A1 FR 2265368A1 FR 7510139 A FR7510139 A FR 7510139A FR 7510139 A FR7510139 A FR 7510139A FR 2265368 A1 FR2265368 A1 FR 2265368A1
Authority
FR
France
Prior art keywords
indoles
schizophrenia
treatment
tranquillizers
carbolines
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7510139A
Other languages
English (en)
French (fr)
Other versions
FR2265368B1 (no
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Inc
Original Assignee
Pfizer Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US456641A external-priority patent/US3925409A/en
Application filed by Pfizer Inc filed Critical Pfizer Inc
Publication of FR2265368A1 publication Critical patent/FR2265368A1/fr
Application granted granted Critical
Publication of FR2265368B1 publication Critical patent/FR2265368B1/fr
Granted legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Anesthesiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Epidemiology (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
FR7510139A 1974-04-01 1975-04-01 Substd. tetrahydro-gamma-carbolines and pyrrolo-(3,4-b)-indoles - as tranquillizers for the treatment of schizophrenia Granted FR2265368A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US45664074A 1974-04-01 1974-04-01
US456641A US3925409A (en) 1974-04-01 1974-04-01 4-Aryl-1,2,3,4-tetrahydropyrrolo{8 3,4-b{9 indoles

Publications (2)

Publication Number Publication Date
FR2265368A1 true FR2265368A1 (en) 1975-10-24
FR2265368B1 FR2265368B1 (no) 1978-07-28

Family

ID=27038317

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7510139A Granted FR2265368A1 (en) 1974-04-01 1975-04-01 Substd. tetrahydro-gamma-carbolines and pyrrolo-(3,4-b)-indoles - as tranquillizers for the treatment of schizophrenia

Country Status (15)

Country Link
JP (1) JPS587635B2 (no)
AR (2) AR207799A1 (no)
AU (1) AU7955975A (no)
DD (1) DD118879A5 (no)
DE (1) DE2514084A1 (no)
DK (2) DK130575A (no)
ES (3) ES436157A1 (no)
FI (1) FI750940A (no)
FR (1) FR2265368A1 (no)
IL (1) IL46925A0 (no)
LU (1) LU72182A1 (no)
NL (1) NL7503700A (no)
NO (1) NO751055L (no)
RO (1) RO72884A (no)
SE (2) SE423630B (no)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4224329A (en) * 1979-01-23 1980-09-23 Pfizer Inc. 2-Substituted-trans-5-aryl-2,3,4,4a,5,9b-hexahydro-1H-pyrido[4,3-b]indoles
US4451655A (en) * 1982-05-17 1984-05-29 Pfizer Inc. Process for preparing carboline derivatives and compounds used in their preparation
CZ294532B6 (cs) * 1998-12-21 2005-01-12 Janssen Pharmaceutica N. V. Benzisoxazoly a fenony jako alfa2-antagonisté, způsob jejich přípravy a použití a farmaceutický prostředek
RU2320662C1 (ru) * 2006-08-24 2008-03-27 Андрей Александрович Иващенко ЗАМЕЩЕННЫЕ ПИРРОЛО[4,3-b]ИНДОЛЫ, КОМБИНАТОРНАЯ И ФОКУСИРОВАННАЯ БИБЛИОТЕКИ, ФАРМАЦЕВТИЧЕСКАЯ КОМПОЗИЦИЯ, СПОСОБЫ ИХ ПОЛУЧЕНИЯ И ПРИМЕНЕНИЯ
US8993572B2 (en) * 2010-04-22 2015-03-31 Intra-Cellular Therapies, Inc. Pyrido[3′,4′:4,5]pyrrolo[1,2,3-de]quinoxalines derivatives and [1,4]oxazino[2,3,4-hi]pyrido[4,3-b]indole derivatives

Also Published As

Publication number Publication date
NL7503700A (nl) 1975-10-03
JPS50140494A (no) 1975-11-11
ES436157A1 (es) 1977-04-16
IL46925A0 (en) 1975-05-22
DD118879A5 (no) 1976-03-20
DE2514084A1 (de) 1975-11-20
DK187878A (da) 1978-05-01
ES453787A1 (es) 1978-01-01
AU7955975A (en) 1976-09-30
RO72884B (ro) 1983-07-30
SE7502927L (no) 1975-10-02
DK130575A (no) 1975-10-02
JPS587635B2 (ja) 1983-02-10
SE8200047L (sv) 1982-01-07
NO751055L (no) 1975-10-02
LU72182A1 (no) 1976-03-02
FR2265368B1 (no) 1978-07-28
SE423630B (sv) 1982-05-17
FI750940A (no) 1975-10-02
AR206812A1 (es) 1976-08-23
AR207799A1 (es) 1976-10-29
ES453788A1 (es) 1978-01-01
RO72884A (ro) 1983-08-03

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Legal Events

Date Code Title Description
ST Notification of lapse