FR2259589A1 - 2-Acylamino-chromones - with cardiac stimulant, analgesic and antiinflammatory, and some with normolipaemic activity - Google Patents
2-Acylamino-chromones - with cardiac stimulant, analgesic and antiinflammatory, and some with normolipaemic activityInfo
- Publication number
- FR2259589A1 FR2259589A1 FR7403584A FR7403584A FR2259589A1 FR 2259589 A1 FR2259589 A1 FR 2259589A1 FR 7403584 A FR7403584 A FR 7403584A FR 7403584 A FR7403584 A FR 7403584A FR 2259589 A1 FR2259589 A1 FR 2259589A1
- Authority
- FR
- France
- Prior art keywords
- substd
- opt
- alkyl
- co2h
- phenyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/22—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
2-Acylamino-chromones of formula (I) (where R is a group where (1) R' is H or alkyl, R2 is alkyl, -CO2H phenyl or phenoxy opt. substd. by >=1 halogens, R3 is H halogen, alkyl or phenyl, or (2) R is alpha-styryl opt. substd. on the aromatic ring by >=1 alkoxy or by a methylenedioxy group to form, with the aromatic ring, a benzo-1,3-dioxol-5-yl group, or (3) R is phenyl, pref. substd. by >=1 halogen, OH, alkoxy or acyloxy, or (4) R is pyridyl-N-oxide or thiazolidinyl-N-oxide, opt. substd. by -CO2H with the free bond on a C-atom, or (5) R is OR4 where R4 is opt. unsatd, alkyl or cycloalkyl substd. by NH2, dialkylamino, OH, -CO2H, phenyl or phenoxy opt. substd. by one or more halogen, OH or alkoxy, isoxazolyl, tetrahydropyranyl, piperidino, morpholino, N-alkyl- or N-arylpiperazino opt. substd. by one or more OH, acetamido or by phenyl opt. substd. by one or more halogen or alkoxy or (6) R is the group where R5 is the group -A-R7 where A is alkylene, R7 is H, dialkylamino, opt. esterified -CO2H, -CONH2, -CONH alkyl CON (alkyl)2 or heterocyclic e.g. imidazolyl or R5 is phenyl opt. substd. by >=1 halogen, CF3 or opt. esterified -CO2H, R6 is H or arlkyl, or R5 + R6 and the attached N-atom may form a piperidino or piperazino group, opt. substd. by alkyl, phenyl, halophenyl, -CO2H or alkoxycarbonyl, Ra and Rb are in positions 5,6,7, or 8 on the benzopyran ring and may be H, halogen, OH, acyloxy or alkoxy). Also their acid-addition salts and the salts of the -CO2H substd. cpds. with bases have analgesic, antiinflammatory, cardiac stimulant activity, and some have normolipaemic activity.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR7403584A FR2259589A1 (en) | 1974-02-04 | 1974-02-04 | 2-Acylamino-chromones - with cardiac stimulant, analgesic and antiinflammatory, and some with normolipaemic activity |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR7403584A FR2259589A1 (en) | 1974-02-04 | 1974-02-04 | 2-Acylamino-chromones - with cardiac stimulant, analgesic and antiinflammatory, and some with normolipaemic activity |
Publications (2)
Publication Number | Publication Date |
---|---|
FR2259589A1 true FR2259589A1 (en) | 1975-08-29 |
FR2259589B1 FR2259589B1 (en) | 1977-11-10 |
Family
ID=9134416
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR7403584A Granted FR2259589A1 (en) | 1974-02-04 | 1974-02-04 | 2-Acylamino-chromones - with cardiac stimulant, analgesic and antiinflammatory, and some with normolipaemic activity |
Country Status (1)
Country | Link |
---|---|
FR (1) | FR2259589A1 (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2411186A1 (en) * | 1977-12-12 | 1979-07-06 | Philagro Sa | NEW DERIVATIVES OF UREIDO-3 (THIO) CHROMONES AND HERBICIDE COMPOSITIONS CONTAINING THEM |
-
1974
- 1974-02-04 FR FR7403584A patent/FR2259589A1/en active Granted
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2411186A1 (en) * | 1977-12-12 | 1979-07-06 | Philagro Sa | NEW DERIVATIVES OF UREIDO-3 (THIO) CHROMONES AND HERBICIDE COMPOSITIONS CONTAINING THEM |
US4259506A (en) * | 1977-12-12 | 1981-03-31 | Philagro | New 3-ureido-(thio)-chromone derivatives |
Also Published As
Publication number | Publication date |
---|---|
FR2259589B1 (en) | 1977-11-10 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
ST | Notification of lapse |